| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Euan Ramsay Orr Allan, Robin Michael Yate. Redundancy between Cysteine Cathepsins in Murine Experimental Autoimmune Encephalomyelitis. PloS one. vol 10. issue 6. 2016-03-04. PMID:26075905. |
utilizing mice deficient in cysteine cathepsins both individually and in combination, we found that the myelin-associated antigen myelin oligodendrocyte glycoprotein (mog) was efficiently processed and presented by macrophages to cd4+ t cells in the individual absence of cathepsin b, s or l. similarly, mice deficient in cathepsin b or s were susceptible to mog-induced eae and displayed clinical progression and immune infiltration into the cns, similar to their wild-type counterparts. |
2016-03-04 |
2023-08-13 |
mouse |
| Maximilian Gahr, Florian Lauda, Moritz E Wigand, Bernhard J Connemann, Angela Rosenbohm, Hayrettin Tumani, Markus Reindl, Zeljko Uzelac, Jan Leweren. Periventricular white matter lesion and incomplete MRZ reaction in a male patient with anti-N-methyl-D-aspartate receptor encephalitis presenting with dysphoric mania. BMJ case reports. vol 2015. 2016-03-01. PMID:25917068. |
in view of the lesion location and the cerebrospinal fluid (csf) findings (incomplete mrz (measles, rubella and varicella zoster) reaction, lymphocytic pleocytosis, intrathecal igg and igm synthesis; absence of aquaporin-4 (aqp4) and myelin oligodendrocyte glycoprotein (mog) antibodies), the presence of a multiple sclerosis-like immune response was discussed. |
2016-03-01 |
2023-08-13 |
Not clear |
| Kaja Kasarello, Barbara Kwiatkowska-Patzer, Andrzej W Lipkowski, Jacek K Bardowski, Agnieszka K Szczepankowsk. Oral Administration of Lactococcus lactis Expressing Synthetic Genes of Myelin Antigens in Decreasing Experimental Autoimmune Encephalomyelitis in Rats. Medical science monitor : international medical journal of experimental and clinical research. vol 21. 2016-02-26. PMID:26026273. |
it was shown in animal models that administration of specific epitopes of the three main myelin proteins - myelin oligodendrocyte glycoprotein (mog), myelin basic protein (mbp), and proteolipid protein (plp) - results in induction of oral tolerance and suppression of disease symptoms. |
2016-02-26 |
2023-08-13 |
human |
| Stylianos Ravanidis, Kyriaki Nepheli Poulatsidou, Roza Lagoudaki, Olga Touloumi, Elena Polyzoidou, Athanasios Lourbopoulos, Evangelia Nousiopoulou, Paschalis Theotokis, Evangelia Kesidou, Dimitrios Tsalikakis, Dimitrios Karacostas, Maria Grigoriou, Katerina Chlichlia, Nikolaos Grigoriadi. Subcutaneous Transplantation of Neural Precursor Cells in Experimental Autoimmune Encephalomyelitis Reduces Chemotactic Signals in the Central Nervous System. Stem cells translational medicine. vol 4. issue 12. 2016-02-23. PMID:26511651. |
npcs were isolated from brains of neonatal c57/bl6 mice and were subcutaneously administered in female mice with myelin oligodendrocyte glycoprotein (mog)-induced eae. |
2016-02-23 |
2023-08-13 |
mouse |
| Youjin Lee, Meike Mitsdoerffer, Sheng Xiao, Guangxiang Gu, Raymond A Sobel, Vijay K Kuchro. IL-21R signaling is critical for induction of spontaneous experimental autoimmune encephalomyelitis. The Journal of clinical investigation. vol 125. issue 11. 2016-02-22. PMID:26413871. |
here, we utilized a transgenic eae mouse model, in which t and b cells overexpress receptors for myelin oligodendrocyte glycoprotein (mog) (referred to as 2d2xth mice), and demonstrated that il-21 is critical for the development of a variant form of spontaneous eae in these animals. |
2016-02-22 |
2023-08-13 |
mouse |
| Adel Mohamed, H M Waris, H Ramadan, M Quereshi, J Kalr. Amelioration of chronic relapsing experimental autoimmune encephalomyelitis (cr-eae) using thymoquinone - biomed 2009. Biomedical sciences instrumentation. vol 45. 2016-02-18. PMID:19369775. |
thirty female mice of strain c57bl/6j and aged between 6 to 12 weeks were placed into 3 groups of 10 and were given myelin oligodendrocyte glycoprotein (mog) subcutaneously (sc) to induce eae. |
2016-02-18 |
2023-08-12 |
mouse |
| B de Andrade Pereira, M Ackermann, S Chaudhary, R Vogel, B Vogt, C Dresch, C Fraefe. Tolerance of activated pathogenic CD4+ T cells by transcriptional targeting of dendritic cells. Gene therapy. vol 22. issue 5. 2016-02-03. PMID:25739989. |
we have recently shown that targeted expression of myelin oligodendrocyte glycoprotein (mog) to dendritic cells with self-inactivating-lentivirus vectors induces antigen-specific tolerance in naive antigen-specific cd4+ t cells and protects mice from experimental autoimmune encephalomyelitis (eae). |
2016-02-03 |
2023-08-13 |
mouse |
| Fernanda Chiuso-Minicucci, Larissa Lumi Watanabe Ishikawa, Luiza Ayumi Nishiyama Mimura, Thais Fernanda de Campos Fraga-Silva, Thais Graziela Donegá França, Sofia Fernanda Gonçalves Zorzella-Pezavento, Camila Marques, Maura Rosane Valerio Ikoma, Alexandrina Sartor. Treatment with Vitamin D/MOG Association Suppresses Experimental Autoimmune Encephalomyelitis. PloS one. vol 10. issue 5. 2016-02-03. PMID:25965341. |
considering the tolerogenic effects of active vitamin d, we evaluated the therapeutic effect of myelin oligodendrocyte glycoprotein (mog) associated with active vitamin d in eae development. |
2016-02-03 |
2023-08-13 |
mouse |
| Jennifer D Hood, Veronika I Zarnitsyna, Cheng Zhu, Brian D Evavol. Regulatory and T Effector Cells Have Overlapping Low to High Ranges in TCR Affinities for Self during Demyelinating Disease. Journal of immunology (Baltimore, Md. : 1950). vol 195. issue 9. 2016-01-27. PMID:26385521. |
it has been demonstrated that during experimental autoimmune encephalomyelitis there are myelin oligodendrocyte glycoprotein (mog)--specific tregs that infiltrate into the cns. |
2016-01-27 |
2023-08-13 |
Not clear |
| Lea Heuer, Martin Beyerbach, Fred Lühder, Andreas Beineke, Christina Strub. Neurotoxocarosis alters myelin protein gene transcription and expression. Parasitology research. vol 114. issue 6. 2016-01-25. PMID:25773181. |
interestingly, 2', 3 ´-cyclic nucleotide 3'-phosphodiesterase (cnp) and myelin oligodendrocyte glycoprotein (mog) were upregulated in both t. canis- and t. cati-infected mice preceding demyelination. |
2016-01-25 |
2023-08-13 |
mouse |
| Min Su, Yinhong Song, Zhixu He, Rong Hu, Debra Rood, Laijun La. Administration of embryonic stem cell-derived thymic epithelial progenitors expressing MOG induces antigen-specific tolerance and ameliorates experimental autoimmune encephalomyelitis. Journal of autoimmunity. vol 58. 2016-01-14. PMID:25618825. |
we show here that transplantation of mesc-teps expressing self-antigen myelin oligodendrocyte glycoprotein (mog) in mice results in enhanced t cell regeneration, long-term expression of mog in the thymus, prevention of experimental autoimmune encephalomyelitis (eae) development, and remission of established eae. |
2016-01-14 |
2023-08-13 |
mouse |
| Masami Tanaka, Keiko Tanak. [Anti-myelin oligodendrocyte glycoprotein (MOG) antibody]. Nihon rinsho. Japanese journal of clinical medicine. vol 73 Suppl 7. 2016-01-14. PMID:26480803. |
[anti-myelin oligodendrocyte glycoprotein (mog) antibody]. |
2016-01-14 |
2023-08-13 |
Not clear |
| Maciej Juryńczyk, Przemysław Lewkowicz, Małgorzata Domowicz, Marcin P Mycko, Krzysztof W Selma. Heat shock protein 70 (Hsp70) interacts with the Notch1 intracellular domain and contributes to the activity of Notch signaling in myelin-reactive CD4 T cells. Journal of neuroimmunology. vol 287. 2016-01-08. PMID:26439956. |
molecular interaction and nuclear colocalization of nicd1 and hsp70 were also detected in cd4 t cells reactive against myelin oligodendrocyte glycoprotein (mog)35-55, which showed hsp70-dependent up-regulation of both nicd1 and notch target genes. |
2016-01-08 |
2023-08-13 |
mouse |
| Hideki Nakajima, Masakatsu Motomura, Keiko Tanaka, Azusa Fujikawa, Ruka Nakata, Yasuhiro Maeda, Tomoaki Shima, Akihiro Mukaino, Shunsuke Yoshimura, Teiichiro Miyazaki, Hirokazu Shiraishi, Atsushi Kawakami, Akira Tsujin. Antibodies to myelin oligodendrocyte glycoprotein in idiopathic optic neuritis. BMJ open. vol 5. issue 4. 2016-01-05. PMID:25838512. |
to investigate the differences of clinical features, cerebrospinal fluid (csf), mri findings and response to steroid therapies between patients with optic neuritis (on) who have myelin oligodendrocyte glycoprotein (mog) antibodies and those who have seronegative on. |
2016-01-05 |
2023-08-13 |
Not clear |
| H-Christian von Büdingen, Feng Mei, Ariele Greenfield, Sarah Jahn, Yun-An A Shen, Hugh H Reid, David D McKemy, Jonah R Cha. The myelin oligodendrocyte glycoprotein directly binds nerve growth factor to modulate central axon circuitry. The Journal of cell biology. vol 210. issue 6. 2015-12-24. PMID:26347141. |
myelin oligodendrocyte glycoprotein (mog) is a central nervous system myelin-specific molecule expressed on the outer lamellae of myelin. |
2015-12-24 |
2023-08-13 |
mouse |
| Phuc T Dang, Quyen Bui, Claretta S D'Souza, Jacqueline M Oria. Modelling MS: Chronic-Relapsing EAE in the NOD/Lt Mouse Strain. Current topics in behavioral neurosciences. vol 26. 2015-12-16. PMID:26126592. |
eae variants generated with the myelin component myelin oligodendrocyte glycoprotein (mog) have emerged as the preferred ones, because in this particular variant disease is associated with both t- and b-cell effector mechanisms, together with demyelination. |
2015-12-16 |
2023-08-13 |
mouse |
| A Rahimi, M Faizi, F Talebi, F Noorbakhsh, F Kahrizi, N Nader. Interaction between the protective effects of cannabidiol and palmitoylethanolamide in experimental model of multiple sclerosis in C57BL/6 mice. Neuroscience. vol 290. 2015-12-15. PMID:25637488. |
we induced experimental autoimmune encephalomyelitis (eae), a model of ms, by injecting myelin oligodendrocyte glycoprotein (mog) to c57bl/6 mice. |
2015-12-15 |
2023-08-13 |
mouse |
| Agostino Bruno, Mario Scrima, Ettore Novellino, Gerardino D'Errico, Anna Maria D'Ursi, Vittorio Limongell. The glycan role in the glycopeptide immunogenicity revealed by atomistic simulations and spectroscopic experiments on the multiple sclerosis biomarker CSF114(Glc). Scientific reports. vol 5. 2015-12-04. PMID:25776265. |
in this conformation csf114(glc) binds the monoclonal antibody mab8-18c5 similarly to the myelin oligodendrocyte glycoprotein mog, which is a known ms auto-antigen, thus explaining its diagnostic activity. |
2015-12-04 |
2023-08-13 |
Not clear |
| Chung-Hsien Li, Ming-Hong Lin, Shih-Han Chu, Pang-Hsien Tu, Cheng-Chieh Fang, Chia-Hung Yen, Peir-In Liang, Jason C Huang, Yu-Chia Su, Huey-Kang Sytwu, Yi-Ming Arthur Che. Role of glycine N-methyltransferase in the regulation of T-cell responses in experimental autoimmune encephalomyelitis. Molecular medicine (Cambridge, Mass.). vol 20. 2015-12-01. PMID:25535034. |
accordingly, myelin oligodendrocyte glycoprotein (mog)-specific t-cell proliferation and induction of t-helper (th)1 and th17 cells were markedly suppressed in mog(35-55)-induced gnmt(-/-) mice. |
2015-12-01 |
2023-08-13 |
mouse |
| Franziska Di Pauli, Romana Höftberger, Markus Reindl, Ronny Beer, Paul Rhomberg, Kathrin Schanda, Douglas Sato, Kazuo Fujihara, Hans Lassmann, Erich Schmutzhard, Thomas Berge. Fulminant demyelinating encephalomyelitis: Insights from antibody studies and neuropathology. Neurology(R) neuroimmunology & neuroinflammation. vol 2. issue 6. 2015-11-20. PMID:26587556. |
antibodies to myelin oligodendrocyte glycoprotein (mog) are detectable in inflammatory demyelinating cns diseases, and mog antibody-associated diseases seem to have a better prognosis despite occasionally severe presentations. |
2015-11-20 |
2023-08-13 |
Not clear |