| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pavel Krejci, Bernard Masri, Vincent Fontaine, Pertchoui B Mekikian, Maryann Weis, Herve Prats, William R Wilco. Interaction of fibroblast growth factor and C-natriuretic peptide signaling in regulation of chondrocyte proliferation and extracellular matrix homeostasis. Journal of cell science. vol 118. issue Pt 21. 2005-12-13. PMID:16234329. |
cnp partially antagonized fgf2-induced expression, release and activation of several matrix-remodeling molecules including matrix metalloproteinase 2 (mmp2), mmp3, mmp9, mmp10 and mmp13. |
2005-12-13 |
2023-08-12 |
mouse |
| Jitesh Pratap, Amjad Javed, Lucia R Languino, Andre J van Wijnen, Janet L Stein, Gary S Stein, Jane B Lia. The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Molecular and cellular biology. vol 25. issue 19. 2005-12-05. PMID:16166639. |
the runx2 (cbfa1/aml3) transcription factor and matrix metalloproteinase 9 (mmp9) are key regulators of growth plate maturation and bone formation. |
2005-12-05 |
2023-08-12 |
mouse |
| Finn Edler von Eyben, Grete Krag Jacobsen, Rolf Inge Skothei. Microinvasive germ cell tumor of the testis. Virchows Archiv : an international journal of pathology. vol 447. issue 3. 2005-11-30. PMID:15968545. |
the mrna levels of invasion-related genes were evaluated based on a dna microarray data set, and we found two gene abnormalities most relevant for the invasion of malignant germ cells: matrix metalloproteinase 9 (mmp9) and plasminogen activator, urokinase (plau) genes were up-regulated in a study comparing tissue samples of tgct and igcn. |
2005-11-30 |
2023-08-12 |
Not clear |
| Xiwu Chen, Yan Su, Barbara Fingleton, Heath Acuff, Lynn M Matrisian, Roy Zent, Ambra Pozz. An orthotopic model of lung cancer to analyze primary and metastatic NSCLC growth in integrin alpha1-null mice. Clinical & experimental metastasis. vol 22. issue 2. 2005-09-26. PMID:16086239. |
mmp9 promotes local tumor progression and distant metastasis in mouse models by enhancing extracellular matrix degradation, releasing vegf from extracellular matrix and promoting vascular pericyte recruitment. |
2005-09-26 |
2023-08-12 |
mouse |
| C Rodolico, A Mazzeo, A Toscano, S Messina, M Aguennouz, M Gaeta, C Messina, G Vit. Specific matrix metalloproteinase expression in focal myositis: an immunopathological study. Acta neurologica Scandinavica. vol 112. issue 3. 2005-09-22. PMID:16097959. |
the aim of our study was to investigate immunoexpression of matrix metalloproteinases mmp2, mmp7 and mmp9 in muscle specimens from patients with focal myositis (fm) vs polymyositis (pm) and dermatomyositis. |
2005-09-22 |
2023-08-12 |
Not clear |
| A Reich, N Jaffe, A Tong, I Lavelin, O Genina, M Pines, D Sklan, A Nussinovitch, E Monsonego-Orna. Weight loading young chicks inhibits bone elongation and promotes growth plate ossification and vascularization. Journal of applied physiology (Bethesda, Md. : 1985). vol 98. issue 6. 2005-08-19. PMID:15677737. |
moreover, weight loading enhanced the penetration of blood vessels into the growth plates and enhanced the gene expression of the matrix metalloproteinases mmp9 and mmp13 in those growth plates. |
2005-08-19 |
2023-08-12 |
Not clear |
| M H Biezeveld, G van Mierlo, R Lutter, I M Kuipers, T Dekker, C E Hack, J W Newburger, T W Kuijper. Sustained activation of neutrophils in the course of Kawasaki disease: an association with matrix metalloproteinases. Clinical and experimental immunology. vol 141. issue 1. 2005-07-29. PMID:15958085. |
plasma levels of human neutrophil elastase (hne), matrix metalloproteinases-2 and -9 (mmp2, mmp9), and neutrophil gelatinase-associated lipocalin (ngal), macrophage neopterin and crp were measured. |
2005-07-29 |
2023-08-12 |
human |
| Perttu J Pöllänen, Terho Lehtimäki, Jussi Mikkelsson, Erkki Ilveskoski, Tarja Kunnas, Markus Perola, Antti Penttilä, Kari M Mattila, Seppo T Nikkari, Kirsi Syrjäkoski, Pekka J Karhune. Matrix metalloproteinase3 and 9 gene promoter polymorphisms: joint action of two loci as a risk factor for coronary artery complicated plaques. Atherosclerosis. vol 180. issue 1. 2005-07-28. PMID:15823277. |
matrix metalloproteinases 3 and 9 (mmp3 and mmp9) are present in atherosclerotic plaques and co-operate in the degradation of the fibrous cap of the atheroma, leading to fissuring and ultimately to acute coronary thrombosis. |
2005-07-28 |
2023-08-12 |
Not clear |
| Ivan Bièche, Tarik Asselah, Ingrid Laurendeau, Dominique Vidaud, Claude Degot, Valérie Paradis, Pierre Bedossa, Dominique-Charles Valla, Patrick Marcellin, Michel Vidau. Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection. Virology. vol 332. issue 1. 2005-05-02. PMID:15661146. |
other genes dysregulated in f1-ch-c, albeit less markedly than ifn-alpha/beta- and ifn-gamma-inducible genes, were mainly involved in the activation of lymphocytes infiltrating the liver (ifng, tnf, cxcl6, il6, ccl8, cxcr3, cxcr4, ccr2), cell proliferation (p16/cdkn2a, mki67, p14/arf), extracellular matrix remodeling (mmp9, itga2), lymphangiogenesis (xlkd1/lyve), oxidative stress (cyp2e1), and cytoskeleton microtubule organization (stmn2/scg10). |
2005-05-02 |
2023-08-12 |
Not clear |
| C M Bamberger, T Else, I Ellebrecht, K Milde-Langosch, D Pankoke, F U Beil, A-M Bamberge. Vitamin B6 modulates glucocorticoid-dependent gene transcription in a promoter- and cell type-specific manner. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. vol 112. issue 10. 2005-04-21. PMID:15578335. |
in contrast, gr-mediated transactivation was strongly inhibited by vitamin b6 in hela cells, while gr-mediated transrepression of a matrix metalloproteinase 9 (mmp9) promoter construct was not affected. |
2005-04-21 |
2023-08-12 |
human |
| Vladimir Vinarsky, Donald L Atkinson, Tamara J Stevenson, Mark T Keating, Shannon J Odelber. Normal newt limb regeneration requires matrix metalloproteinase function. Developmental biology. vol 279. issue 1. 2005-04-18. PMID:15708560. |
this analysis, coupled with a direct cloning approach, identified a previously unknown notophthalmus collagenase gene (ncol) and three known matrix metalloproteinase (mmp) genes, mmp3/10a, mmp3/10b, and mmp9, all of which are upregulated within hours of limb amputation. |
2005-04-18 |
2023-08-12 |
Not clear |
| Peiyu Pu, Chunsheng Kang, Jie Li, Hao Jian. Antisense and dominant-negative AKT2 cDNA inhibits glioma cell invasion. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 25. issue 4. 2005-04-14. PMID:15557754. |
the secretion of matrix metalloproteinases (mmps), mmp2 and mmp9, was determined by gelatin zymography. |
2005-04-14 |
2023-08-12 |
rat |
| Mepur H Ravindranath, Sakunthala Muthugounder, Naftali Presser, Subramanian Viswanatha. Anticancer therapeutic potential of soy isoflavone, genistein. Advances in experimental medicine and biology. vol 546. 2005-03-22. PMID:15584372. |
by blocking the activities of ptk, topoisomerase ii and matrix metalloprotein (mmp9) and by down-regulating the expression of about 11 genes, including that of vascular endothelial growth factor (vegf), genistein can arrest cell growth and proliferation, cell cycle at g2/m, invasion and angiogenesis. |
2005-03-22 |
2023-08-12 |
human |
| Jian-Guo Tang, Xuan Li, Ping Che. Expression of matrix metalloproteinase 9 in nasopharyngeal carcinoma and association with Epstein-Barr virus infection. Journal of Zhejiang University. Science. vol 5. issue 10. 2005-03-08. PMID:15362205. |
to evaluate the expression of matrix metalloproteinase-9 (mmp9) in nasopharyngeal carcinoma and the association between mmp9 and epstein-barr virus infection. |
2005-03-08 |
2023-08-12 |
Not clear |
| E Kettunen, A G Nicholson, B Nagy, H Wikman, J K Seppänen, T Stjernvall, T Ollikainen, V Kinnula, S Nordling, J Hollmén, S Anttila, S Knuutil. L1CAM, INP10, P-cadherin, tPA and ITGB4 over-expression in malignant pleural mesotheliomas revealed by combined use of cDNA and tissue microarray. Carcinogenesis. vol 26. issue 1. 2005-02-22. PMID:15447976. |
there was a type-specific up-regulation of semaphorin e, itgb4 and p-cadherin in epithelioid mm, matrix metalloproteinase 9 (mmp9) and tissue-type plasminogen activator (tpa) in sarcomatoid mm and neural cell adhesion molecule l1 (l1cam) and inp10 in biphasic mm. |
2005-02-22 |
2023-08-12 |
Not clear |
| Natalie K Schiller, Audrey S Black, Gary P Bradshaw, David J Bonnet, Linda K Curtis. Participation of macrophages in atherosclerotic lesion morphology in LDLr-/- mice. Journal of lipid research. vol 45. issue 8. 2005-02-08. PMID:15175354. |
cultured bone marrow-derived macrophages from ldlr-/- and beige,ldlr-/- mice were compared for their ability to accumulate cholesterol, efflux cholesterol, migrate in response to chemotactic stimuli through matrigel-coated membranes, and express matrix metalloproteinase 9 (mmp9). |
2005-02-08 |
2023-08-12 |
mouse |
| J Hulkkonen, M Pertovaara, J Antonen, A Pasternack, M Hurme, P Pöllänen, T Lehtimäk. Matrix metalloproteinase 9 (MMP-9) gene polymorphism and MMP-9 plasma levels in primary Sjogren's syndrome. Rheumatology (Oxford, England). vol 43. issue 12. 2005-02-03. PMID:15316122. |
to determine whether plasma matrix metalloproteinase 9 (mmp-9) and mmp9 (-1562c-->t) polymorphism have an effect on the disease phenotype in primary sjogren's syndrome (pss). |
2005-02-03 |
2023-08-12 |
Not clear |
| Emilia Mira, Rosa Ana Lacalle, José María Buesa, Gonzalo González de Buitrago, Sonia Jiménez-Baranda, Concepción Gómez-Moutón, Carlos Martínez-A, Santos Mañe. Secreted MMP9 promotes angiogenesis more efficiently than constitutive active MMP9 bound to the tumor cell surface. Journal of cell science. vol 117. issue Pt 9. 2004-12-28. PMID:15075244. |
association of matrix metalloprotease 9 (mmp9) to the cell membrane is considered important in tumor growth and angiogenesis. |
2004-12-28 |
2023-08-12 |
mouse |
| J Dittmer, M Vetter, S G Blumenthal, R K Lindemann, H Kölb. Importance of ets1 proto-oncogene for breast cancer progression. Zentralblatt fur Gynakologie. vol 126. issue 4. 2004-12-09. PMID:15389378. |
of the ets1-responsive proteases, matrix metalloproteases mmp1 and mmp9, but not mmp3 or upa, showed reduced rna levels when endogenous ets1 expression was suppressed. |
2004-12-09 |
2023-08-12 |
Not clear |
| Jack Lawler, Michael Detma. Tumor progression: the effects of thrombospondin-1 and -2. The international journal of biochemistry & cell biology. vol 36. issue 6. 2004-12-02. PMID:15094119. |
the normal suppression of angiogenesis by tsp-1 and -2 involves multiple mechanisms including direct interaction with vascular endothelial cell growth factor (vegf), inhibition of matrix metalloproteinase 9 (mmp9) activation, inhibition of endothelial cell migration and induction of endothelial cell apoptosis. |
2004-12-02 |
2023-08-12 |
Not clear |