| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David A Sorrell, Malgorzata Szymanowska, Marion Boutinaud, Claire Robinson, Richard W E Clarkson, Torsten Stein, David J Flint, Andreas F Kol. Regulation of genes encoding proteolytic enzymes during mammary gland development. The Journal of dairy research. vol 72. issue 4. 2006-01-26. PMID:16223458. |
matrix metalloproteinases (mmp) are expressed in several cell types of the mammary gland including stromal fibroblasts (e.g., mmp3, mmp2), epithelial cells (e.g., mmp7 or mmp9), adipocytes (e.g., mmp2) and lymphoid cells (e.g., mmp9) (crawford et al. |
2006-01-26 |
2023-08-12 |
mouse |
| Pavel Krejci, Bernard Masri, Vincent Fontaine, Pertchoui B Mekikian, Maryann Weis, Herve Prats, William R Wilco. Interaction of fibroblast growth factor and C-natriuretic peptide signaling in regulation of chondrocyte proliferation and extracellular matrix homeostasis. Journal of cell science. vol 118. issue Pt 21. 2005-12-13. PMID:16234329. |
cnp partially antagonized fgf2-induced expression, release and activation of several matrix-remodeling molecules including matrix metalloproteinase 2 (mmp2), mmp3, mmp9, mmp10 and mmp13. |
2005-12-13 |
2023-08-12 |
mouse |
| Jitesh Pratap, Amjad Javed, Lucia R Languino, Andre J van Wijnen, Janet L Stein, Gary S Stein, Jane B Lia. The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Molecular and cellular biology. vol 25. issue 19. 2005-12-05. PMID:16166639. |
the runx2 (cbfa1/aml3) transcription factor and matrix metalloproteinase 9 (mmp9) are key regulators of growth plate maturation and bone formation. |
2005-12-05 |
2023-08-12 |
mouse |
| Finn Edler von Eyben, Grete Krag Jacobsen, Rolf Inge Skothei. Microinvasive germ cell tumor of the testis. Virchows Archiv : an international journal of pathology. vol 447. issue 3. 2005-11-30. PMID:15968545. |
the mrna levels of invasion-related genes were evaluated based on a dna microarray data set, and we found two gene abnormalities most relevant for the invasion of malignant germ cells: matrix metalloproteinase 9 (mmp9) and plasminogen activator, urokinase (plau) genes were up-regulated in a study comparing tissue samples of tgct and igcn. |
2005-11-30 |
2023-08-12 |
Not clear |
| Xiwu Chen, Yan Su, Barbara Fingleton, Heath Acuff, Lynn M Matrisian, Roy Zent, Ambra Pozz. An orthotopic model of lung cancer to analyze primary and metastatic NSCLC growth in integrin alpha1-null mice. Clinical & experimental metastasis. vol 22. issue 2. 2005-09-26. PMID:16086239. |
mmp9 promotes local tumor progression and distant metastasis in mouse models by enhancing extracellular matrix degradation, releasing vegf from extracellular matrix and promoting vascular pericyte recruitment. |
2005-09-26 |
2023-08-12 |
mouse |
| C Rodolico, A Mazzeo, A Toscano, S Messina, M Aguennouz, M Gaeta, C Messina, G Vit. Specific matrix metalloproteinase expression in focal myositis: an immunopathological study. Acta neurologica Scandinavica. vol 112. issue 3. 2005-09-22. PMID:16097959. |
the aim of our study was to investigate immunoexpression of matrix metalloproteinases mmp2, mmp7 and mmp9 in muscle specimens from patients with focal myositis (fm) vs polymyositis (pm) and dermatomyositis. |
2005-09-22 |
2023-08-12 |
Not clear |
| A Reich, N Jaffe, A Tong, I Lavelin, O Genina, M Pines, D Sklan, A Nussinovitch, E Monsonego-Orna. Weight loading young chicks inhibits bone elongation and promotes growth plate ossification and vascularization. Journal of applied physiology (Bethesda, Md. : 1985). vol 98. issue 6. 2005-08-19. PMID:15677737. |
moreover, weight loading enhanced the penetration of blood vessels into the growth plates and enhanced the gene expression of the matrix metalloproteinases mmp9 and mmp13 in those growth plates. |
2005-08-19 |
2023-08-12 |
Not clear |
| M H Biezeveld, G van Mierlo, R Lutter, I M Kuipers, T Dekker, C E Hack, J W Newburger, T W Kuijper. Sustained activation of neutrophils in the course of Kawasaki disease: an association with matrix metalloproteinases. Clinical and experimental immunology. vol 141. issue 1. 2005-07-29. PMID:15958085. |
plasma levels of human neutrophil elastase (hne), matrix metalloproteinases-2 and -9 (mmp2, mmp9), and neutrophil gelatinase-associated lipocalin (ngal), macrophage neopterin and crp were measured. |
2005-07-29 |
2023-08-12 |
human |
| Perttu J Pöllänen, Terho Lehtimäki, Jussi Mikkelsson, Erkki Ilveskoski, Tarja Kunnas, Markus Perola, Antti Penttilä, Kari M Mattila, Seppo T Nikkari, Kirsi Syrjäkoski, Pekka J Karhune. Matrix metalloproteinase3 and 9 gene promoter polymorphisms: joint action of two loci as a risk factor for coronary artery complicated plaques. Atherosclerosis. vol 180. issue 1. 2005-07-28. PMID:15823277. |
matrix metalloproteinases 3 and 9 (mmp3 and mmp9) are present in atherosclerotic plaques and co-operate in the degradation of the fibrous cap of the atheroma, leading to fissuring and ultimately to acute coronary thrombosis. |
2005-07-28 |
2023-08-12 |
Not clear |
| Ivan Bièche, Tarik Asselah, Ingrid Laurendeau, Dominique Vidaud, Claude Degot, Valérie Paradis, Pierre Bedossa, Dominique-Charles Valla, Patrick Marcellin, Michel Vidau. Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection. Virology. vol 332. issue 1. 2005-05-02. PMID:15661146. |
other genes dysregulated in f1-ch-c, albeit less markedly than ifn-alpha/beta- and ifn-gamma-inducible genes, were mainly involved in the activation of lymphocytes infiltrating the liver (ifng, tnf, cxcl6, il6, ccl8, cxcr3, cxcr4, ccr2), cell proliferation (p16/cdkn2a, mki67, p14/arf), extracellular matrix remodeling (mmp9, itga2), lymphangiogenesis (xlkd1/lyve), oxidative stress (cyp2e1), and cytoskeleton microtubule organization (stmn2/scg10). |
2005-05-02 |
2023-08-12 |
Not clear |
| C M Bamberger, T Else, I Ellebrecht, K Milde-Langosch, D Pankoke, F U Beil, A-M Bamberge. Vitamin B6 modulates glucocorticoid-dependent gene transcription in a promoter- and cell type-specific manner. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. vol 112. issue 10. 2005-04-21. PMID:15578335. |
in contrast, gr-mediated transactivation was strongly inhibited by vitamin b6 in hela cells, while gr-mediated transrepression of a matrix metalloproteinase 9 (mmp9) promoter construct was not affected. |
2005-04-21 |
2023-08-12 |
human |
| Vladimir Vinarsky, Donald L Atkinson, Tamara J Stevenson, Mark T Keating, Shannon J Odelber. Normal newt limb regeneration requires matrix metalloproteinase function. Developmental biology. vol 279. issue 1. 2005-04-18. PMID:15708560. |
this analysis, coupled with a direct cloning approach, identified a previously unknown notophthalmus collagenase gene (ncol) and three known matrix metalloproteinase (mmp) genes, mmp3/10a, mmp3/10b, and mmp9, all of which are upregulated within hours of limb amputation. |
2005-04-18 |
2023-08-12 |
Not clear |
| Peiyu Pu, Chunsheng Kang, Jie Li, Hao Jian. Antisense and dominant-negative AKT2 cDNA inhibits glioma cell invasion. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 25. issue 4. 2005-04-14. PMID:15557754. |
the secretion of matrix metalloproteinases (mmps), mmp2 and mmp9, was determined by gelatin zymography. |
2005-04-14 |
2023-08-12 |
rat |
| Mepur H Ravindranath, Sakunthala Muthugounder, Naftali Presser, Subramanian Viswanatha. Anticancer therapeutic potential of soy isoflavone, genistein. Advances in experimental medicine and biology. vol 546. 2005-03-22. PMID:15584372. |
by blocking the activities of ptk, topoisomerase ii and matrix metalloprotein (mmp9) and by down-regulating the expression of about 11 genes, including that of vascular endothelial growth factor (vegf), genistein can arrest cell growth and proliferation, cell cycle at g2/m, invasion and angiogenesis. |
2005-03-22 |
2023-08-12 |
human |
| Jian-Guo Tang, Xuan Li, Ping Che. Expression of matrix metalloproteinase 9 in nasopharyngeal carcinoma and association with Epstein-Barr virus infection. Journal of Zhejiang University. Science. vol 5. issue 10. 2005-03-08. PMID:15362205. |
to evaluate the expression of matrix metalloproteinase-9 (mmp9) in nasopharyngeal carcinoma and the association between mmp9 and epstein-barr virus infection. |
2005-03-08 |
2023-08-12 |
Not clear |
| E Kettunen, A G Nicholson, B Nagy, H Wikman, J K Seppänen, T Stjernvall, T Ollikainen, V Kinnula, S Nordling, J Hollmén, S Anttila, S Knuutil. L1CAM, INP10, P-cadherin, tPA and ITGB4 over-expression in malignant pleural mesotheliomas revealed by combined use of cDNA and tissue microarray. Carcinogenesis. vol 26. issue 1. 2005-02-22. PMID:15447976. |
there was a type-specific up-regulation of semaphorin e, itgb4 and p-cadherin in epithelioid mm, matrix metalloproteinase 9 (mmp9) and tissue-type plasminogen activator (tpa) in sarcomatoid mm and neural cell adhesion molecule l1 (l1cam) and inp10 in biphasic mm. |
2005-02-22 |
2023-08-12 |
Not clear |
| Natalie K Schiller, Audrey S Black, Gary P Bradshaw, David J Bonnet, Linda K Curtis. Participation of macrophages in atherosclerotic lesion morphology in LDLr-/- mice. Journal of lipid research. vol 45. issue 8. 2005-02-08. PMID:15175354. |
cultured bone marrow-derived macrophages from ldlr-/- and beige,ldlr-/- mice were compared for their ability to accumulate cholesterol, efflux cholesterol, migrate in response to chemotactic stimuli through matrigel-coated membranes, and express matrix metalloproteinase 9 (mmp9). |
2005-02-08 |
2023-08-12 |
mouse |
| J Hulkkonen, M Pertovaara, J Antonen, A Pasternack, M Hurme, P Pöllänen, T Lehtimäk. Matrix metalloproteinase 9 (MMP-9) gene polymorphism and MMP-9 plasma levels in primary Sjogren's syndrome. Rheumatology (Oxford, England). vol 43. issue 12. 2005-02-03. PMID:15316122. |
to determine whether plasma matrix metalloproteinase 9 (mmp-9) and mmp9 (-1562c-->t) polymorphism have an effect on the disease phenotype in primary sjogren's syndrome (pss). |
2005-02-03 |
2023-08-12 |
Not clear |
| Emilia Mira, Rosa Ana Lacalle, José María Buesa, Gonzalo González de Buitrago, Sonia Jiménez-Baranda, Concepción Gómez-Moutón, Carlos Martínez-A, Santos Mañe. Secreted MMP9 promotes angiogenesis more efficiently than constitutive active MMP9 bound to the tumor cell surface. Journal of cell science. vol 117. issue Pt 9. 2004-12-28. PMID:15075244. |
association of matrix metalloprotease 9 (mmp9) to the cell membrane is considered important in tumor growth and angiogenesis. |
2004-12-28 |
2023-08-12 |
mouse |
| J Dittmer, M Vetter, S G Blumenthal, R K Lindemann, H Kölb. Importance of ets1 proto-oncogene for breast cancer progression. Zentralblatt fur Gynakologie. vol 126. issue 4. 2004-12-09. PMID:15389378. |
of the ets1-responsive proteases, matrix metalloproteases mmp1 and mmp9, but not mmp3 or upa, showed reduced rna levels when endogenous ets1 expression was suppressed. |
2004-12-09 |
2023-08-12 |
Not clear |