| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Margaret Nieborowska-Skorska, Grazyna Hoser, Lori Rink, Maciej Malecki, Plamen Kossev, Mariusz A Wasik, Tomasz Skorsk. Id1 transcription inhibitor-matrix metalloproteinase 9 axis enhances invasiveness of the breakpoint cluster region/abelson tyrosine kinase-transformed leukemia cells. Cancer research. vol 66. issue 8. 2006-06-07. PMID:16618731. |
the id1-promoted cell invasiveness was seemingly mediated by matrix metalloproteinase 9 (mmp9). |
2006-06-07 |
2023-08-12 |
mouse |
| Christine Varon, Florence Tatin, Violaine Moreau, Ellen Van Obberghen-Schilling, Samantha Fernandez-Sauze, Edith Reuzeau, Ijsbrand Kramer, Elisabeth Géno. Transforming growth factor beta induces rosettes of podosomes in primary aortic endothelial cells. Molecular and cellular biology. vol 26. issue 9. 2006-05-23. PMID:16611998. |
mt1-mmp and metalloprotease 9 (mmp9), both upregulated by tgf-beta, were detected at sites of podosome formation, and mt1-mmp was found to be involved in the local degradation of extracellular matrix proteins beneath the podosomes and required for the invasion of collagen gels by endothelial cells. |
2006-05-23 |
2023-08-12 |
Not clear |
| Douglas G Walker, John Link, Lih-Fen Lue, Jessica E Dalsing-Hernandez, Barry E Boye. Gene expression changes by amyloid beta peptide-stimulated human postmortem brain microglia identify activation of multiple inflammatory processes. Journal of leukocyte biology. vol 79. issue 3. 2006-05-02. PMID:16365156. |
the results demonstrated that abeta activation of microglia induced a large alteration in gene transcription including activation of many proinflammatory cytokines and chemokines, most notably, interleukin (il)-1beta, il-8, and matrix metalloproteinases (mmp), including mmp1, mmp3, mmp9, mmp10, and mmp12. |
2006-05-02 |
2023-08-12 |
human |
| Albert Quintana, Mercedes Giralt, Santiago Rojas, Milena Penkowa, Iain L Campbell, Juan Hidalgo, Amalia Moliner. Differential role of tumor necrosis factor receptors in mouse brain inflammatory responses in cryolesion brain injury. Journal of neuroscience research. vol 82. issue 5. 2006-04-28. PMID:16267827. |
lack of tnfr1 signaling also affected the expression of apoptosis/cell death-related genes (fas, rip, p53), matrix metalloproteinases (mmp3, mmp9, mmp12), and their inhibitors (timp1), suggesting a role of tnfr1 in extracellular matrix remodeling after injury. |
2006-04-28 |
2023-08-12 |
mouse |
| Shazia Malik, Kate Day, Isabelle Perrault, D Stephen Charnock-Jones, Stephen K Smit. Menstrual effluent in endometriosis shows no difference in volume, VEGF-A, MMP2 and MMP9 or sFLT. Reproductive biomedicine online. vol 12. issue 2. 2006-04-24. PMID:16478582. |
in addition, vascular endothelial growth factor-a (vegf-a) message and protein, soluble truncated receptor svegf-r1 (sflt), matrix metalloproteinase (mmp) 2 and mmp9 activities were also shown to be similar between the two groups. |
2006-04-24 |
2023-08-12 |
Not clear |
| Deepak Kumar, Willa Fung, Robert M Moore, Vishal Pandey, Jennifer Fox, Bradley Stetzer, Joseph M Mansour, Brian M Mercer, Raymond W Redline, John J Moor. Proinflammatory cytokines found in amniotic fluid induce collagen remodeling, apoptosis, and biophysical weakening of cultured human fetal membranes. Biology of reproduction. vol 74. issue 1. 2006-04-17. PMID:16148217. |
matrix metalloproteinase 9 (mmp9) protein increased, tissue inhibitor of matrix metalloproteinase 3 (timp3) protein decreased, and poly (adp-ribose) polymerase (parp1) cleavage increased with increasing tnf or il1b doses (all p < 0.05), suggesting collagen remodeling and apoptosis. |
2006-04-17 |
2023-08-12 |
human |
| Ray F Gariano, Diane Hu, Jill Helm. Expression of angiogenesis-related genes during retinal development. Gene expression patterns : GEP. vol 6. issue 2. 2006-04-17. PMID:16330258. |
expression of flk, flt1, the matrix metalloproteinase mt1-mmp, and the tissue inhibitor of metalloproteinase timp2, but not of mmp2, mmp9, timp1, or timp3, correlates with inner retinal vascularization. |
2006-04-17 |
2023-08-12 |
mouse |
| Jerry H Brow. Breaking symmetry in protein dimers: designs and functions. Protein science : a publication of the Protein Society. vol 15. issue 1. 2006-03-23. PMID:16373473. |
these functions include regulation of muscle contraction by tropomyosin, blood clot formation by fibrin, half-of-site reactivity of caspase-9, and adaptive protein recognition in the matrix metalloproteinase mmp9. |
2006-03-23 |
2023-08-12 |
cattle |
| J Decock, W Hendrickx, H Wildiers, M R Christiaens, P Neven, M Drijkoningen, R Paridaen. Plasma gelatinase levels in patients with primary breast cancer in relation to axillary lymph node status, Her2/neu expression and other clinicopathological variables. Clinical & experimental metastasis. vol 22. issue 6. 2006-02-14. PMID:16320112. |
matrix metalloproteinases (mmps), in particular the gelatinases mmp2 and mmp9, are important mediators of tumour invasion and metastasis. |
2006-02-14 |
2023-08-12 |
Not clear |
| David A Sorrell, Malgorzata Szymanowska, Marion Boutinaud, Claire Robinson, Richard W E Clarkson, Torsten Stein, David J Flint, Andreas F Kol. Regulation of genes encoding proteolytic enzymes during mammary gland development. The Journal of dairy research. vol 72. issue 4. 2006-01-26. PMID:16223458. |
matrix metalloproteinases (mmp) are expressed in several cell types of the mammary gland including stromal fibroblasts (e.g., mmp3, mmp2), epithelial cells (e.g., mmp7 or mmp9), adipocytes (e.g., mmp2) and lymphoid cells (e.g., mmp9) (crawford et al. |
2006-01-26 |
2023-08-12 |
mouse |
| Pavel Krejci, Bernard Masri, Vincent Fontaine, Pertchoui B Mekikian, Maryann Weis, Herve Prats, William R Wilco. Interaction of fibroblast growth factor and C-natriuretic peptide signaling in regulation of chondrocyte proliferation and extracellular matrix homeostasis. Journal of cell science. vol 118. issue Pt 21. 2005-12-13. PMID:16234329. |
cnp partially antagonized fgf2-induced expression, release and activation of several matrix-remodeling molecules including matrix metalloproteinase 2 (mmp2), mmp3, mmp9, mmp10 and mmp13. |
2005-12-13 |
2023-08-12 |
mouse |
| Jitesh Pratap, Amjad Javed, Lucia R Languino, Andre J van Wijnen, Janet L Stein, Gary S Stein, Jane B Lia. The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Molecular and cellular biology. vol 25. issue 19. 2005-12-05. PMID:16166639. |
the runx2 (cbfa1/aml3) transcription factor and matrix metalloproteinase 9 (mmp9) are key regulators of growth plate maturation and bone formation. |
2005-12-05 |
2023-08-12 |
mouse |
| Finn Edler von Eyben, Grete Krag Jacobsen, Rolf Inge Skothei. Microinvasive germ cell tumor of the testis. Virchows Archiv : an international journal of pathology. vol 447. issue 3. 2005-11-30. PMID:15968545. |
the mrna levels of invasion-related genes were evaluated based on a dna microarray data set, and we found two gene abnormalities most relevant for the invasion of malignant germ cells: matrix metalloproteinase 9 (mmp9) and plasminogen activator, urokinase (plau) genes were up-regulated in a study comparing tissue samples of tgct and igcn. |
2005-11-30 |
2023-08-12 |
Not clear |
| Xiwu Chen, Yan Su, Barbara Fingleton, Heath Acuff, Lynn M Matrisian, Roy Zent, Ambra Pozz. An orthotopic model of lung cancer to analyze primary and metastatic NSCLC growth in integrin alpha1-null mice. Clinical & experimental metastasis. vol 22. issue 2. 2005-09-26. PMID:16086239. |
mmp9 promotes local tumor progression and distant metastasis in mouse models by enhancing extracellular matrix degradation, releasing vegf from extracellular matrix and promoting vascular pericyte recruitment. |
2005-09-26 |
2023-08-12 |
mouse |
| C Rodolico, A Mazzeo, A Toscano, S Messina, M Aguennouz, M Gaeta, C Messina, G Vit. Specific matrix metalloproteinase expression in focal myositis: an immunopathological study. Acta neurologica Scandinavica. vol 112. issue 3. 2005-09-22. PMID:16097959. |
the aim of our study was to investigate immunoexpression of matrix metalloproteinases mmp2, mmp7 and mmp9 in muscle specimens from patients with focal myositis (fm) vs polymyositis (pm) and dermatomyositis. |
2005-09-22 |
2023-08-12 |
Not clear |
| A Reich, N Jaffe, A Tong, I Lavelin, O Genina, M Pines, D Sklan, A Nussinovitch, E Monsonego-Orna. Weight loading young chicks inhibits bone elongation and promotes growth plate ossification and vascularization. Journal of applied physiology (Bethesda, Md. : 1985). vol 98. issue 6. 2005-08-19. PMID:15677737. |
moreover, weight loading enhanced the penetration of blood vessels into the growth plates and enhanced the gene expression of the matrix metalloproteinases mmp9 and mmp13 in those growth plates. |
2005-08-19 |
2023-08-12 |
Not clear |
| M H Biezeveld, G van Mierlo, R Lutter, I M Kuipers, T Dekker, C E Hack, J W Newburger, T W Kuijper. Sustained activation of neutrophils in the course of Kawasaki disease: an association with matrix metalloproteinases. Clinical and experimental immunology. vol 141. issue 1. 2005-07-29. PMID:15958085. |
plasma levels of human neutrophil elastase (hne), matrix metalloproteinases-2 and -9 (mmp2, mmp9), and neutrophil gelatinase-associated lipocalin (ngal), macrophage neopterin and crp were measured. |
2005-07-29 |
2023-08-12 |
human |
| Perttu J Pöllänen, Terho Lehtimäki, Jussi Mikkelsson, Erkki Ilveskoski, Tarja Kunnas, Markus Perola, Antti Penttilä, Kari M Mattila, Seppo T Nikkari, Kirsi Syrjäkoski, Pekka J Karhune. Matrix metalloproteinase3 and 9 gene promoter polymorphisms: joint action of two loci as a risk factor for coronary artery complicated plaques. Atherosclerosis. vol 180. issue 1. 2005-07-28. PMID:15823277. |
matrix metalloproteinases 3 and 9 (mmp3 and mmp9) are present in atherosclerotic plaques and co-operate in the degradation of the fibrous cap of the atheroma, leading to fissuring and ultimately to acute coronary thrombosis. |
2005-07-28 |
2023-08-12 |
Not clear |
| Ivan Bièche, Tarik Asselah, Ingrid Laurendeau, Dominique Vidaud, Claude Degot, Valérie Paradis, Pierre Bedossa, Dominique-Charles Valla, Patrick Marcellin, Michel Vidau. Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection. Virology. vol 332. issue 1. 2005-05-02. PMID:15661146. |
other genes dysregulated in f1-ch-c, albeit less markedly than ifn-alpha/beta- and ifn-gamma-inducible genes, were mainly involved in the activation of lymphocytes infiltrating the liver (ifng, tnf, cxcl6, il6, ccl8, cxcr3, cxcr4, ccr2), cell proliferation (p16/cdkn2a, mki67, p14/arf), extracellular matrix remodeling (mmp9, itga2), lymphangiogenesis (xlkd1/lyve), oxidative stress (cyp2e1), and cytoskeleton microtubule organization (stmn2/scg10). |
2005-05-02 |
2023-08-12 |
Not clear |
| C M Bamberger, T Else, I Ellebrecht, K Milde-Langosch, D Pankoke, F U Beil, A-M Bamberge. Vitamin B6 modulates glucocorticoid-dependent gene transcription in a promoter- and cell type-specific manner. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. vol 112. issue 10. 2005-04-21. PMID:15578335. |
in contrast, gr-mediated transactivation was strongly inhibited by vitamin b6 in hela cells, while gr-mediated transrepression of a matrix metalloproteinase 9 (mmp9) promoter construct was not affected. |
2005-04-21 |
2023-08-12 |
human |