| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sylvia Fong, Leslie Mounkes, Yong Liu, Michael Maibaum, Eric Alonzo, Pierre-Yves Desprez, Ann D Thor, Mohammed Kashani-Sabet, Robert J Deb. Functional identification of distinct sets of antitumor activities mediated by the FKBP gene family. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 24. 2004-02-02. PMID:14612567. |
we then used gene expression profiling to identify syndecan 1 (sdc1) and matrix metalloproteinase 9 (mmp9) as genes directly regulated by fkbp1a and fkbp8. |
2004-02-02 |
2023-08-12 |
mouse |
| Koh-ichi Sakata, Masaaki Satoh, Masanori Someya, Hiroko Asanuma, Hisayasu Nagakura, Atushi Oouchi, Kensei Nakata, Katsuhisa Kogawa, Kazumitsu Koito, Masato Hareyama, Tetsuo Him. Expression of matrix metalloproteinase 9 is a prognostic factor in patients with non-Hodgkin lymphoma. Cancer. vol 100. issue 2. 2004-01-30. PMID:14716772. |
in in vitro studies, matrix metalloproteinase 9 (mmp9) was reportedly expressed by human nhl cells and elevated levels of mmp9 have been observed in a subset of patients with high-grade nhl. |
2004-01-30 |
2023-08-12 |
human |
| Hirotaka Kuga, Takashi Morisaki, Katsuya Nakamura, Hideya Onishi, Hirokazu Noshiro, Akihiko Uchiyama, Masao Tanaka, Mitsuo Katan. Interferon-gamma suppresses transforming growth factor-beta-induced invasion of gastric carcinoma cells through cross-talk of Smad pathway in a three-dimensional culture model. Oncogene. vol 22. issue 49. 2003-12-03. PMID:14586410. |
tgf-beta induced the enhanced expression of matrix metalloproteinase 9 (mmp9) and urokinase-type plasminogen activator (upa) in gctm-1 at both the protein and enzymatic activity levels. |
2003-12-03 |
2023-08-12 |
human |
| Dorina Belotti, Paola Paganoni, Luigi Manenti, Angela Garofalo, Sergio Marchini, Giulia Taraboletti, Raffaella Giavazz. Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation. Cancer research. vol 63. issue 17. 2003-11-06. PMID:14500349. |
matrix metalloproteinases (mmp9 and mmp2) induce the release of vascular endothelial growth factor (vegf) by ovarian carcinoma cells: implications for ascites formation. |
2003-11-06 |
2023-08-12 |
mouse |
| Céline Colnot, Zachary Thompson, Theodore Miclau, Zena Werb, Jill A Helm. Altered fracture repair in the absence of MMP9. Development (Cambridge, England). vol 130. issue 17. 2003-10-06. PMID:12874132. |
here, we provide the first genetic evidence that matrix metalloproteinase 9 (mmp9) regulates crucial events during adult fracture repair. |
2003-10-06 |
2023-08-12 |
mouse |
| Yi Sun, Lu-Jia Don. [Role of matrix metalloproteinases in the pathogenesis and therapy of leukemia]. Zhongguo shi yan xue ye xue za zhi. vol 11. issue 3. 2003-09-09. PMID:12844422. |
mmp2 and mmp9 are the unique types of proteinase that hydrolyze the bone structure of excellulary matrix (type iv collagen). |
2003-09-09 |
2023-08-12 |
Not clear |
| J E Nutt, G C Durkan, J K Mellon, J Lune. Matrix metalloproteinases (MMPs) in bladder cancer: the induction of MMP9 by epidermal growth factor and its detection in urine. BJU international. vol 91. issue 1. 2003-03-25. PMID:12614260. |
matrix metalloproteinases (mmps) in bladder cancer: the induction of mmp9 by epidermal growth factor and its detection in urine. |
2003-03-25 |
2023-08-12 |
Not clear |
| Brigitte Lelongt, Pierre Ronc. Role of matrix metalloproteinases in kidney development and glomerulopathy: lessons from transgenic mice. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. vol 17 Suppl 9. 2003-03-18. PMID:12386280. |
matrix metalloproteinase-9 (mmp9) is required for renal organogenesis in vitro and is increased in various nephropathies. |
2003-03-18 |
2023-08-12 |
mouse |
| Alison M Wallace, Andrew J Sandfor. Genetic polymorphisms of matrix metalloproteinases: functional importance in the development of chronic obstructive pulmonary disease? American journal of pharmacogenomics : genomics-related research in drug development and clinical practice. vol 2. issue 3. 2003-03-03. PMID:12383023. |
here we review evidence that genetic polymorphisms in matrix metalloproteinase genes mmp1, mmp9 and mmp12 may be important in the development of copd. |
2003-03-03 |
2023-08-12 |
Not clear |
| Patricia A Elkins, Yen Sen Ho, Ward W Smith, Cheryl A Janson, Karla J D'Alessio, Michael S McQueney, Maxwell D Cummings, Anne M Romani. Structure of the C-terminally truncated human ProMMP9, a gelatin-binding matrix metalloproteinase. Acta crystallographica. Section D, Biological crystallography. vol 58. issue Pt 7. 2003-02-11. PMID:12077439. |
the x-ray crystal structure of the proform of human matrix metalloproteinase mmp9 has been solved to 2.5 a resolution. |
2003-02-11 |
2023-08-12 |
human |
| Mijung Kwon, Sooryun Seo, Hoyoung Chun, Jun-Mo Chung, In Kwon Chung, Kyu Chung Hu. Dual effect of nerve growth factor on cell death of PC12 cells Induced by serum deprivation. Molecules and cells. vol 13. issue 2. 2003-01-29. PMID:12018837. |
the acceleration of cell death in the ngf-treated cells was anoikis, caused by the loss of the anchorage of the cell via the action of increased activities of matrix metalloproteinases (mmp2, mmp9). |
2003-01-29 |
2023-08-12 |
Not clear |
| Carol A Hitchon, Carol L Danning, Gabor G Illei, Hani S El-Gabalawy, Dimitrios T Boumpa. Gelatinase expression and activity in the synovium and skin of patients with erosive psoriatic arthritis. The Journal of rheumatology. vol 29. issue 1. 2002-07-02. PMID:11824946. |
matrix metalloproteinases (mmp), especially the gelatinases (mmp2, mmp9), have been implicated in several features of inflammatory arthritis including angiogenesis and bone erosions. |
2002-07-02 |
2023-08-12 |
Not clear |
| Bruno Legallicier, Germain Trugnan, Gillian Murphy, Brigitte Lelongt, Pierre Ronc. Expression of the type IV collagenase system during mouse kidney development and tubule segmentation. Journal of the American Society of Nephrology : JASN. vol 12. issue 11. 2002-02-15. PMID:11675412. |
type iv collagenases matrix metalloproteinase-2 (mmp2) and mmp9 and their related proteins, mt1-mmp, tissue inhibitor of metalloproteinases 1 (timp1), timp2, and timp3, are expressed during kidney morphogenesis and nephrogenesis, but the renal ontogeny of these proteins is only partially known, and their persistence in the adult remains controversial. |
2002-02-15 |
2023-08-12 |
mouse |
| Bruno Legallicier, Germain Trugnan, Gillian Murphy, Brigitte Lelongt, Pierre Ronc. Expression of the type IV collagenase system during mouse kidney development and tubule segmentation. Journal of the American Society of Nephrology : JASN. vol 12. issue 11. 2002-02-15. PMID:11675412. |
all components persisted in specific segments of the adult renal tubule, where mmp9, mmp2, and mt1-mmp showed an apical expression, suggesting that substrates for these enzymes should be in the tubule lumen or in the apical cell domain and not in the extracellular matrix. |
2002-02-15 |
2023-08-12 |
mouse |
| A S Rigg, N R Lemoin. Adenoviral delivery of TIMP1 or TIMP2 can modify the invasive behavior of pancreatic cancer and can have a significant antitumor effect in vivo. Cancer gene therapy. vol 8. issue 11. 2002-02-14. PMID:11773977. |
pancreatic carcinomas overexpress several matrix metalloproteinases (mmps), in particular mmp2 and mmp9. |
2002-02-14 |
2023-08-12 |
mouse |
| S Lepidi, R D Kenagy, E W Raines, E S Chiu, A Chait, R Ross, A W Clowe. MMP9 production by human monocyte-derived macrophages is decreased on polymerized type I collagen. Journal of vascular surgery. vol 34. issue 6. 2002-01-18. PMID:11743569. |
the production of matrix metalloproteinases (mmps), such as mmp9, by macrophages may be a critical factor in the rupture of unstable atherosclerotic plaques and aortic aneurysms. |
2002-01-18 |
2023-08-12 |
human |
| S Lepidi, R D Kenagy, E W Raines, E S Chiu, A Chait, R Ross, A W Clowe. MMP9 production by human monocyte-derived macrophages is decreased on polymerized type I collagen. Journal of vascular surgery. vol 34. issue 6. 2002-01-18. PMID:11743569. |
therefore, we studied the role of matrix and soluble cytokines in the regulation of monocyte/macrophage expression of mmp9. |
2002-01-18 |
2023-08-12 |
human |
| J F Maddo. Mapping the matrix metalloproteinase 9 (MMP9) gene and the BL1071 microsatellite to ovine chromosome 13 (OAR13). Animal genetics. vol 32. issue 5. 2002-01-17. PMID:11683731. |
mapping the matrix metalloproteinase 9 (mmp9) gene and the bl1071 microsatellite to ovine chromosome 13 (oar13). |
2002-01-17 |
2023-08-12 |
Not clear |
| M H Rabinowitz, R C Andrews, J D Becherer, D M Bickett, D G Bubacz, J G Conway, D J Cowan, M Gaul, K Glennon, M H Lambert, M A Leesnitzer, D L McDougald, M L Moss, D L Musso, M C Rizzoli. Design of selective and soluble inhibitors of tumor necrosis factor-alpha converting enzyme (TACE). Journal of medicinal chemistry. vol 44. issue 24. 2001-12-12. PMID:11708926. |
inhibitors containing these arginine mimetics were found to have increased solubility in simulated gastric fluid (sgf) relative to 1, allowing for the incorporation of lipophilic p1' side chains which had the effect of retaining potent tace inhibition, but reducing potency against matrix metalloproteases (mmps) thus increasing overall selectivity against mmp1, mmp3, and mmp9. |
2001-12-12 |
2023-08-12 |
rat |
| J C Rodriguez-Manzaneque, T F Lane, M A Ortega, R O Hynes, J Lawler, M L Iruela-Arisp. Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 22. 2001-12-04. PMID:11606713. |
interestingly, absence of tsp1 resulted in increased association of vascular endothelial growth factor (vegf) with its receptor vegfr2 and higher levels of active matrix metalloproteinase-9 (mmp9), a molecule previously shown to facilitate both angiogenesis and tumor invasion. |
2001-12-04 |
2023-08-12 |
mouse |