| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peter C Meighan, Starla E Meighan, Elizabeth D Rich, R Lane Brown, Michael D Varnu. Matrix metalloproteinase-9 and -2 enhance the ligand sensitivity of photoreceptor cyclic nucleotide-gated channels. Channels (Austin, Tex.). vol 6. issue 3. 2012-12-07. PMID:22699690. |
extracellular proteases mmp9 and -2 are present in the interphotoreceptor matrix adjacent to photoreceptor outer segments. |
2012-12-07 |
2023-08-12 |
mouse |
| Nathanael D Pruett, Zoltan Hajdu, Jing Zhang, Richard P Visconti, Michael J Kern, Deneen M Wellik, Mark W Majesky, Alexander Awgulewitsc. Changing topographic Hox expression in blood vessels results in regionally distinct vessel wall remodeling. Biology open. vol 1. issue 5. 2012-12-06. PMID:23213434. |
the results suggest direct transcriptional control of two members of the matrix metalloproteinase (mmp) family, including mmp2 and mmp9 that are known as key players in the inception and progression of vascular remodeling events. |
2012-12-06 |
2023-08-12 |
mouse |
| Alpna Tyagi, Chapla Agarwal, Lori D Dwyer-Nield, Rana P Singh, Alvin M Malkinson, Rajesh Agarwa. Silibinin modulates TNF-α and IFN-γ mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells. Molecular carcinogenesis. vol 51. issue 10. 2012-11-30. PMID:21882257. |
importantly, silibinin pretreatment inhibited cytokine mixture-induced phosphorylation of stat3, stat1, and erk1/2, nf-κb-dna binding, and expression of cox2, inos, matrix metalloproteinases (mmp)2, and mmp9, which was mediated through impairment of stat3 and stat1 nuclear localization. |
2012-11-30 |
2023-08-12 |
mouse |
| Avshesh Mishra, Anshika Srivastava, T Mittal, N Garg, B Mitta. Association of matrix metalloproteinases (MMP2, MMP7 and MMP9) genetic variants with left ventricular dysfunction in coronary artery disease patients. Clinica chimica acta; international journal of clinical chemistry. vol 413. issue 19-20. 2012-11-28. PMID:22664146. |
association of matrix metalloproteinases (mmp2, mmp7 and mmp9) genetic variants with left ventricular dysfunction in coronary artery disease patients. |
2012-11-28 |
2023-08-12 |
Not clear |
| Chunhong Wang, Guangru Fei, Zhongmin Liu, Qinchuan Li, Zengguang Xu, Tao Re. HMGB1 was a pivotal synergistic effecor for CpG oligonucleotide to enhance the progression of human lung cancer cells. Cancer biology & therapy. vol 13. issue 9. 2012-11-26. PMID:22617774. |
we observed a myd88-dependent upregulation of matrix metalloproteinase (mmp) 2, mmp9 and cyclin-dependent kinase (cdk) 2 in 95d cells in response to hmgb1. |
2012-11-26 |
2023-08-12 |
human |
| Bimmer E Claessen, Gregg W Stone, Roxana Mehran, Bernhard Witzenbichler, Bruce R Brodie, Jochen Wöhrle, Adam Witkowski, Giulio Guagliumi, Krzysztof Zmudka, José P S Henriques, Jan G P Tijssen, Elias A Sanidas, Vasiliki Chantziara, Diaa Hakim, Selene Leon, Ke Xu, George D Danga. Relationship between biomarkers and subsequent clinical and angiographic restenosis after paclitaxel-eluting stents for treatment of STEMI: a HORIZONS-AMI substudy. Journal of thrombosis and thrombolysis. vol 34. issue 2. 2012-11-19. PMID:22466810. |
at 30-day follow-up lower values of il-1ra (il-1ra), matrix metalloproteinase 9 (mmp9), and myeloperoxidase (mpo), and a decline relative to admission in il-1ra, monocyte chemotactic protein-1 (mcp-1), and mmp9 were associated with higher in-stent late loss. |
2012-11-19 |
2023-08-12 |
Not clear |
| Jennifer M Wu, Anthony G Visco, Elizabeth A Grass, Damian M Craig, Rebekah G Fulton, Carol Haynes, Alison C Weidner, Svati H Sha. Matrix metalloproteinase-9 genetic polymorphisms and the risk for advanced pelvic organ prolapse. Obstetrics and gynecology. vol 120. issue 3. 2012-10-29. PMID:22914468. |
matrix metalloproteinase-9 (mmp9) is a protease associated with degradation of collagen and elastin. |
2012-10-29 |
2023-08-12 |
Not clear |
| Teni G Ebrahimian, Claire Squiban, Telma Roque, Haydee Lugo-Martinez, Mohamad Hneino, Valerie Buard, Patrick Gourmelon, Marc Benderitter, Fabien Milliat, Radia Tamara. Plasminogen activator inhibitor-1 controls bone marrow-derived cells therapeutic effect through MMP9 signaling: role in physiological and pathological wound healing. Stem cells (Dayton, Ohio). vol 30. issue 7. 2012-10-19. PMID:22570200. |
we assessed the role of plasminogen activator inhibitor-1 (pai-1) and matrix metalloproteinase 9 (mmp9) in wound healing process and in the bone marrow mononuclear cells (bmmnc)-related effects on physiological and pathological wound healing. |
2012-10-19 |
2023-08-12 |
mouse |
| Jea-Hyun Baek, Carmen Birchmeier, Martin Zenke, Thomas Hieronymu. The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity. Journal of immunology (Baltimore, Md. : 1950). vol 189. issue 4. 2012-10-19. PMID:22802413. |
additionally, we found that met signaling regulates matrix metalloproteinase mmp2 and mmp9 activity, which is important for dc migration through extracellular matrix. |
2012-10-19 |
2023-08-12 |
mouse |
| Donna K Arnett, Robyn L McClelland, Alan Bank, David A Bluemke, Mary Cushman, Alexander J Szalai, Nishank Jain, Antoinette S Gomes, Susan R Heckbert, W Gregory Hundley, João A Lim. Biomarkers of inflammation and hemostasis associated with left ventricular mass: The Multiethnic Study of Atherosclerosis (MESA). International journal of molecular epidemiology and genetics. vol 2. issue 4. 2012-10-02. PMID:22200000. |
we studied relationships of c-reactive protein (crp), interleukin-6 (il6), d-dimer, soluble intercellular adhesion molecule-1 (sicam-1), plasminogen activator inhibitor 1 (pai-1), soluble thrombomodulin (stm), soluble tumor necrosis factor type 1 receptor (stnfr1), von willebrand factor (vwf), soluble e-selectin (se-selectin), factor viii, fibrinogen, matrix metalloproteinase 3 (mmp3), and matrix metalloproteinase 9 (mmp9) with lv mass in an asymptomatic population. |
2012-10-02 |
2023-08-12 |
human |
| Stephen W Mamber, Volkan Gurel, Ryan G Rhodes, John McMichae. Effects of streptolysin o on extracellular matrix gene expression in normal human epidermal keratinocytes. Dose-response : a publication of International Hormesis Society. vol 9. issue 4. 2012-10-02. PMID:22461761. |
downregulated genes of interest were mmp9 (encoding matrix metalloproteinase 9) and spp1 (encoding osteopontin). |
2012-10-02 |
2023-08-12 |
human |
| Ida K Lund, Morten G Rasch, Signe Ingvarsen, Jesper Pass, Daniel H Madsen, Lars H Engelholm, Niels Behrendt, Gunilla Høyer-Hanse. Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo. Frontiers in pharmacology. vol 3. 2012-10-02. PMID:22754528. |
mabs against proteins involved in extracellular proteolysis, including plasminogen activators urokinase plasminogen activator (upa), tissue-type plasminogen activator (tpa), their inhibitor pai-1, the upa receptor (upar), two matrix metalloproteinases (mmp9 and mmp14), as well as the collagen internalization receptor uparap, have been developed. |
2012-10-02 |
2023-08-12 |
mouse |
| I Dafnis, A K Tzinia, E C Tsilibary, V I Zannis, A Chron. An apolipoprotein E4 fragment affects matrix metalloproteinase 9, tissue inhibitor of metalloproteinase 1 and cytokine levels in brain cell lines. Neuroscience. vol 210. 2012-09-21. PMID:22445724. |
western blot and zymography analysis showed that treatment of sk-n-sh cells with apoe4[Δ(186-299)], but not full-length apoe4 or the shorter apoe4[Δ(166-299)] fragment, leads to increased extracellular levels of matrix metalloproteinase 9 (mmp9) and tissue inhibitor of metalloproteinase 1 (timp1). |
2012-09-21 |
2023-08-12 |
human |
| Fang Yu, Qingping Jiang, Ying Zhou, Zhen Yang, Xiaoli Yu, Hao Wang, Zhen Liu, Lijing Wang, Weiyi Fang, Suiqun Gu. Abnormal expression of matrix metalloproteinase-9 (MMP9) correlates with clinical course in Chinese patients with endometrial cancer. Disease markers. vol 32. issue 5. 2012-09-21. PMID:22674412. |
abnormal expression of matrix metalloproteinase-9 (mmp9) correlates with clinical course in chinese patients with endometrial cancer. |
2012-09-21 |
2023-08-12 |
Not clear |
| Fang Yu, Qingping Jiang, Ying Zhou, Zhen Yang, Xiaoli Yu, Hao Wang, Zhen Liu, Lijing Wang, Weiyi Fang, Suiqun Gu. Abnormal expression of matrix metalloproteinase-9 (MMP9) correlates with clinical course in Chinese patients with endometrial cancer. Disease markers. vol 32. issue 5. 2012-09-21. PMID:22674412. |
the aim of the present study was to analyze the expression of matrix metalloproteinase-9 (mmp9) in endometrial cancer and its correlation with clinicopathologic features in chinese patients, including the survival of patients with endometrial cancer. |
2012-09-21 |
2023-08-12 |
Not clear |
| Bing Xu, Hui Chen, Wei Xu, Wenming Zhang, Sue Buckley, Song Guo Zheng, David Warburton, Martin Kolb, Jack Gauldie, Wei Sh. Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. American journal of physiology. Lung cellular and molecular physiology. vol 303. issue 2. 2012-09-20. PMID:22610349. |
previous studies have found that inappropriate elevation of matrix metalloproteinase-9 (mmp9) expression and activity is coincident with early onset of emphysema in smad3-null mice. |
2012-09-20 |
2023-08-12 |
mouse |
| Sang Jun Han, Shannon M Hawkins, Khurshida Begum, Sung Yun Jung, Ertug Kovanci, Jun Qin, John P Lydon, Francesco J DeMayo, Bert W O'Malle. A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nature medicine. vol 18. issue 7. 2012-09-19. PMID:22660634. |
tnf⁻/⁻ and mmp9⁻/⁻ mice with surgically induced endometriosis showed that activation of tumor necrosis factor a (tnf-α)-induced matrix metallopeptidase 9 (mmp9) activity mediates formation of the 70-kda src-1 c-terminal isoform in endometriotic mouse tissue. |
2012-09-19 |
2023-08-12 |
mouse |
| Pei-Li Yao, Yi-Chen Lin, John H Richbur. Mono-(2-ethylhexyl) phthalate (MEHP) promotes invasion and migration of human testicular embryonal carcinoma cells. Biology of reproduction. vol 86. issue 5. 2012-09-17. PMID:22321834. |
in this study, we show that mono-(2-ethylhexyl) phthalate (mehp) induces matrix metalloproteinase 2 (mmp2) expression in testicular embryonal carcinoma nt2/d1 cells but has no significant effect on mmp9 expression. |
2012-09-17 |
2023-08-12 |
human |
| Song Li, Sixun Yu, Chunqing Zhang, Haifeng Shu, Shiyong Liu, Ning An, Meihua Yang, Qing Yin, Hui Yan. Increased expression of matrix metalloproteinase 9 in cortical lesions from patients with focal cortical dysplasia type IIb and tuberous sclerosis complex. Brain research. vol 1453. 2012-09-17. PMID:22459050. |
matrix metalloproteinase 9 (mmp9), a typical extracellular matrix proteolytic protease, has been shown to participate in the occurrence of seizures in experimental models. |
2012-09-17 |
2023-08-12 |
Not clear |
| Eliza Wiercinska, Hildegonda P H Naber, Evangelia Pardali, Gabri van der Pluijm, Hans van Dam, Peter ten Dijk. The TGF-β/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system. Breast cancer research and treatment. vol 128. issue 3. 2012-09-13. PMID:20821046. |
interestingly, both a broad spectrum matrix metalloproteinase (mmp) inhibitor and a selective mmp2 and mmp9 inhibitor mitigated tgf-β-induced invasion of m4 cells, while leaving basal invasion intact. |
2012-09-13 |
2023-08-12 |
Not clear |