| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emma H Allott, Joanne Lysaght, Mary Clare Cathcart, Claire L Donohoe, Robert Cummins, Sarah A McGarrigle, Elaine Kay, John V Reynolds, Graham P Pidgeo. MMP9 expression in oesophageal adenocarcinoma is upregulated with visceral obesity and is associated with poor tumour differentiation. Molecular carcinogenesis. vol 52. issue 2. 2013-04-15. PMID:22121096. |
following co-culture with visceral adipose tissue explants, expression of genes involved in tumour cell invasion and metastasis (matrix metalloproteinase (mmp)2 and mmp9) were upregulated between 10-fold (mmp2) and 5000-fold (mmp9), and expression of tumour suppressor p53 was downregulated 2-fold in oac cell lines. |
2013-04-15 |
2023-08-12 |
Not clear |
| Z Nasr, F Robert, J A Porco, W J Muller, J Pelletie. eIF4F suppression in breast cancer affects maintenance and progression. Oncogene. vol 32. issue 7. 2013-04-12. PMID:22484424. |
translation of vascular endothelial growth factor (vegf), matrix metallopeptidase 9 (mmp9) and cyclin d1 mrnas, which encode products associated with the metastatic phenotype, is inhibited upon eif4e suppression. |
2013-04-12 |
2023-08-12 |
human |
| Cangel Pui-yee Chan, Hui-lin Jiang, Ling-yan Leung, Wai-man Wan, Nga-man Cheng, Wai-sze Ip, Kwan-yee Cheung, Rebecca Wing-yan Chan, Lawrence Ka-sing Wong, Colin Alexander Graham, Reinhard Renneberg, Timothy Hudson Raine. Multiple atherosclerosis-related biomarkers associated with short- and long-term mortality after stroke. Clinical biochemistry. vol 45. issue 16-17. 2013-04-08. PMID:22728010. |
we investigated the relationships of biomarkers of various pathophysiologic pathways including high-sensitivity c-reactive protein (hs-crp), lipocalin-2 (lcn2), myeloperoxidase (mpo) and matrix metalloproteinases 9 (mmp9) with mortality in stroke patients. |
2013-04-08 |
2023-08-12 |
Not clear |
| Lou Zhong, Fei Cao, Qingsheng Yo. Effect of TRAF6 on the biological behavior of human lung adenocarcinoma cell. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 34. issue 1. 2013-03-28. PMID:23055197. |
at the same time, we explored the effects of traf6 on the expression of the following proteins: phosphor-nf-κb (p-p65), cyclin d1, caspase-3, and matrix metalloproteinase 9 (mmp9). |
2013-03-28 |
2023-08-12 |
human |
| Maria Schache, Paul N Bair. Assessment of the association of matrix metalloproteinases with myopia, refractive error and ocular biometric measures in an Australian cohort. PloS one. vol 7. issue 10. 2013-03-28. PMID:23077567. |
the matrix metalloproteinases (mmps) falling into the collagenase (mmp1, mmp8, mmp13), gelatinase (mmp2, mmp9) and stromelysin (mmp3, mmp10, mmp11) functional groups are particularly important. |
2013-03-28 |
2023-08-12 |
Not clear |
| Qinmin Li, Ruihua Shi, Yundong Wang, Xiaoping Ni. TAGLN suppresses proliferation and invasion, and induces apoptosis of colorectal carcinoma cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 34. issue 1. 2013-03-28. PMID:23138394. |
the effect of talgn on the expression of matrix metalloproteinase 9 (mmp9) was detected by western blot. |
2013-03-28 |
2023-08-12 |
Not clear |
| Xiaodong Wang, Yan Yiu Yu, Shirley Lieu, Frank Yang, Jeffrey Lang, Chuanyong Lu, Zena Werb, Diane Hu, Theodore Miclau, Ralph Marcucio, Céline Colno. MMP9 regulates the cellular response to inflammation after skeletal injury. Bone. vol 52. issue 1. 2013-03-25. PMID:23010105. |
we then exploited matrix metalloproteinase 9 (mmp9) that is expressed in inflammatory cells and osteoclasts, and which we previously showed is a potential regulator of cell fate decisions during fracture repair. |
2013-03-25 |
2023-08-12 |
mouse |
| Xiangrui Meng, Peng Lu, Hua Bai, Peng Xiao, Qingxia Fa. Transcriptional regulatory networks in human lung adenocarcinoma. Molecular medicine reports. vol 6. issue 5. 2013-03-19. PMID:22895549. |
among these genes, it appears that: pparg promotes the ppar signaling pathway via the upregulation of lipoprotein lipase (lpl) expression, but suppresses the cell cycle pathway via downregulation of growth arrest and dna-damage-inducible, γ (gadd45g) expression; etv4 stimulates matrix metallopeptidase 9 (mmp9) expression to induce the bladder cancer pathway; fli upregulates transforming growth factor, β receptor ii (tgfbr2) expression to activate tgf-β signaling and upregulates cyclin d3 (ccnd3) expression to promote the cell cycle pathway; nfkb1 upregulates interleukin 1, β (il-1b) expression and initiates the prostate cancer pathway; cebpb upregulates il-6 expression and promotes pathways in cancer; and tal1 promotes kinase insert domain receptor (kdr) expression to promote the tgf-β signaling pathway. |
2013-03-19 |
2023-08-12 |
human |
| Sherif A Ibrahim, George W Yip, Christian Stock, Jun-Wei Pan, Claudia Neubauer, Michaela Poeter, Danute Pupjalis, Chuay Yeng Koo, Reinhard Kelsch, Roland Schüle, Ursula Rescher, Ludwig Kiesel, Martin Gött. Targeting of syndecan-1 by microRNA miR-10b promotes breast cancer cell motility and invasiveness via a Rho-GTPase- and E-cadherin-dependent mechanism. International journal of cancer. vol 131. issue 6. 2013-03-11. PMID:22573479. |
affymetrix screening and confirmatory qpcr and western blotting analysis of syndecan-1-deficient cells revealed upregulation of atf-2, cox-2, cadherin-11, vinculin, actin γ 2, myl9, transgelin-1, rhoa/c, matrix metalloproteinase 2 (mmp2) and heparanase, and downregulation of aml1/runx1, e-cadherin, cldn1, p21waf/cip, cyclin-dependent kinase 6, tlr-4, pai1/2, collagen1alpha1, jhdm1d, mpp4, mmp9, matrilin-2 and anxa3/a10. |
2013-03-11 |
2023-08-12 |
Not clear |
| Xiang-Rong Liu, Mei Luo, Feng Yan, Chen-Cheng Zhang, Si-Jie Li, Hai-Ping Zhao, Xun-Ming Ji, Yu-Min Lu. Ischemic postconditioning diminishes matrix metalloproteinase 9 expression and attenuates loss of the extracellular matrix proteins in rats following middle cerebral artery occlusion and reperfusion. CNS neuroscience & therapeutics. vol 18. issue 10. 2013-03-08. PMID:22925005. |
this study aimed at validating the neuroprotective effects of ipostc and investigating whether the neuroprotection of ipostc is associated with matrix metalloproteinase 9 (mmp9) and the extracellular matrix proteins, laminin and fibronectin, following cerebral ischemia/reperfusion in rats. |
2013-03-08 |
2023-08-12 |
rat |
| Dawei Li, Xing Sun, Dongwang Yan, Jianfeng Huang, Qiongzhen Luo, Huamei Tang, Zhihai Pen. Piwil2 modulates the proliferation and metastasis of colon cancer via regulation of matrix metallopeptidase 9 transcriptional activity. Experimental biology and medicine (Maywood, N.J.). vol 237. issue 10. 2013-02-05. PMID:23104504. |
the possible roles of piwil2 in the regulation of a 2 kb matrix metallopeptidase 9 (mmp9) promoter fragment and on the regulation of apoptotic pathways were evaluated by using a luciferase reporter construct and western blots, respectively. |
2013-02-05 |
2023-08-12 |
human |
| M Dolcino, E Cozzani, S Riva, A Parodi, E Tinazzi, C Lunardi, A Puccett. Gene expression profiling in dermatitis herpetiformis skin lesions. Clinical & developmental immunology. vol 2012. 2013-01-31. PMID:22991566. |
degs also indicate overproduction of matrix proteases (mmp9, adam9, and adam19) and proteolytic enzymes (ctsg, ela2, cpa3, tpsb2, and cma1) that may contribute to epidermal splitting and blister formation. |
2013-01-31 |
2023-08-12 |
Not clear |
| Tingting Qiu, Xiaofei Qi, Jiannong Cen, Zixing Che. Rap1GAP alters leukemia cell differentiation, apoptosis and invasion in vitro. Oncology reports. vol 28. issue 2. 2013-01-24. PMID:22614916. |
in addition, we found that increased expression of rap1gap promoted leukemia cell invasion may be due to matrix metalloproteinase 9 (mmp9). |
2013-01-24 |
2023-08-12 |
human |
| Z Zhang, Z-Y Zhang, Y Wu, H J Schluesene. Valproic acid ameliorates inflammation in experimental autoimmune encephalomyelitis rats. Neuroscience. vol 221. 2013-01-23. PMID:22800566. |
both preventive (from day 0 to day 18) and therapeutic (from day 7 to day 18 or from day 9 to day 19) vpa (500 mg/kg, intra-gastric) administration to eae rats once daily greatly reduced the severity and duration of eae, and suppressed mrna levels of interferon-γ (ifn-γ), tumor necrosis factor-α (tnf-α), interleukin-1β (il-1β) and il-17, matrix metalloproteinase 9 (mmp9), inducible nitric oxide synthase (inos) and transcription factor t-bet, but increased levels of il-4 mrna in eae spinal cords. |
2013-01-23 |
2023-08-12 |
rat |
| Luke Martin McCaffrey, JoAnne Montalbano, Constantina Mihai, Ian G Macar. Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis. Cancer cell. vol 22. issue 5. 2013-01-21. PMID:23153534. |
par3 depletion was associated with induction of mmp9, destruction of the extracellular matrix, and invasion, all mediated by atypical pkc-dependant jak/stat3 activation. |
2013-01-21 |
2023-08-12 |
human |
| Mervi Toriseva, Matti Laato, Olli Carpén, Suvi T Ruohonen, Eriika Savontaus, Masaki Inada, Stephen M Krane, Veli-Matti Kähär. MMP-13 regulates growth of wound granulation tissue and modulates gene expression signatures involved in inflammation, proteolysis, and cell viability. PloS one. vol 7. issue 8. 2013-01-10. PMID:22880047. |
the expression of matrix metalloproteinases mmp2, mmp3, mmp9 was also significantly downregulated in granulation tissue of mmp13(-/-) mice compared to wt mice. |
2013-01-10 |
2023-08-12 |
mouse |
| Guoqing Li, Yu Zhang, Yayun Qian, Hua Zhang, Shiyu Guo, Masataka Sunagawa, Tadashi Hisamitsu, Yanqing Li. Interleukin-17A promotes rheumatoid arthritis synoviocytes migration and invasion under hypoxia by increasing MMP2 and MMP9 expression through NF-κB/HIF-1α pathway. Molecular immunology. vol 53. issue 3. 2013-01-10. PMID:22960198. |
we further showed that a proinvasive effect of il-17a on flss under hypoxia might be through upregulation of matrix metalloproteinase 2 (mmp2) and mmp9. |
2013-01-10 |
2023-08-12 |
Not clear |
| Rui T Peixoto, Portia A Kunz, Hyungbae Kwon, Angela M Mabb, Bernardo L Sabatini, Benjamin D Philpot, Michael D Ehler. Transsynaptic signaling by activity-dependent cleavage of neuroligin-1. Neuron. vol 76. issue 2. 2013-01-02. PMID:23083741. |
nlg1 cleavage is triggered by nmda receptor activation, requires ca2+ /calmodulin-dependent protein kinase, and is mediated by proteolytic activity of matrix metalloprotease 9 (mmp9). |
2013-01-02 |
2023-08-12 |
Not clear |
| A V Mali, U V Wagh, M V Hegde, S S Chandorkar, S V Surve, M V Patol. In vitro anti-metastatic activity of enterolactone, a mammalian lignan derived from flax lignan, and down-regulation of matrix metalloproteinases in MCF-7 and MDA MB 231 cell lines. Indian journal of cancer. vol 49. issue 1. 2012-12-31. PMID:22842186. |
actin cytoskeleton is involved in actin-based cell adhesion, cell motility, and matrix metalloproteinases(mmps) mmp2, mmp9, mmp11 and mmp14 are responsible for cell invasion in breast cancer metastasis. |
2012-12-31 |
2023-08-12 |
human |
| Christelle Langevin, Mar Blanco, Samuel A M Martin, Luc Jouneau, Jean-Francois Bernardet, Armel Houel, Aurélie Lunazzi, Eric Duchaud, Christian Michel, Edwige Quillet, Pierre Boudino. Transcriptional responses of resistant and susceptible fish clones to the bacterial pathogen Flavobacterium psychrophilum. PloS one. vol 7. issue 6. 2012-12-13. PMID:22720048. |
the matrix metalloproteases mmp9 and mmp13 were among the most highly induced genes in both genetic backgrounds. |
2012-12-13 |
2023-08-12 |
Not clear |