| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Santosh Gowda, David A Weinstein, Timothy D Blalock, Kavita Gandhi, Bruce A Mast, Gloria Chin, Gregory S Schult. Topical application of recombinant platelet-derived growth factor increases the rate of healing and the level of proteins that regulate this response. International wound journal. vol 12. issue 5. 2016-07-07. PMID:24118782. |
levels of tumour necrosis factor-alpha (tnfa), interleukin 1-beta (il1b) and both the latent and active forms of matrix metalloproteinase 2 (mmp2) and 9 (mmp9) were measured. |
2016-07-07 |
2023-08-12 |
rat |
| Hui Li, Yu-Han Meng, Wen-Qing Shang, Li-Bing Liu, Xuan Chen, Min-Min Yuan, Li-Ping Jin, Ming-Qing Li, Da-Jin L. Chemokine CCL24 promotes the growth and invasiveness of trophoblasts through ERK1/2 and PI3K signaling pathways in human early pregnancy. Reproduction (Cambridge, England). vol 150. issue 5. 2016-07-06. PMID:26316550. |
in addition, analysis of the downstream signaling pathways of ccl24/ccr3 show that extracellular signal-regulated kinases (erk1/2) and phosphoinositide 3-kinase (pi3k) pathways may contribute to the proliferation, viability and invasiveness of trophoblasts by activating intracellular molecules ki67 and matrix metallopeptidase 9 (mmp9). |
2016-07-06 |
2023-08-13 |
human |
| Min Long, Montserrat Rojo de la Vega, Qing Wen, Manish Bharara, Tao Jiang, Rui Zhang, Shiwen Zhou, Pak K Wong, Georg T Wondrak, Hongting Zheng, Donna D Zhan. An Essential Role of NRF2 in Diabetic Wound Healing. Diabetes. vol 65. issue 3. 2016-07-06. PMID:26718502. |
in a streptozotocin-induced diabetes mouse model, nrf2(-/-) mice have delayed wound closure rates compared with nrf2(+/+) mice, which is, at least partially, due to greater oxidative dna damage, low transforming growth factor-β1 (tgf-β1) and high matrix metalloproteinase 9 (mmp9) expression, and increased apoptosis. |
2016-07-06 |
2023-08-13 |
mouse |
| Zhongshou Zhu, Yiyun Hong, Yan Wang, Guanwen He, Shengnan Y. [The significance of keratinocyte in hyperproliferation of middle ear cholesteatoma]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 30. issue 2. 2016-07-06. PMID:27192911. |
in order to investigate the interaction between the cytokines and keratinocyte and determine the role of cytokines in hyperproliferative of chronic otitis media with cholesteatoma, we observe the expression of matrix metalloproteinase 9 (mmp9), vascular endothelial growth factor (vegf), keratinocyte growth factor (kgf) and its receptor (kgfr) in middle ear cholesteatoma. |
2016-07-06 |
2023-08-13 |
Not clear |
| Hye Jung Ihn, Doohyun Lee, Taeho Lee, Sang-Hyun Kim, Hong-In Shin, Yong Chul Bae, Jung Min Hong, Eui Kyun Par. Inhibitory Effects of KP-A159, a Thiazolopyridine Derivative, on Osteoclast Differentiation, Function, and Inflammatory Bone Loss via Suppression of RANKL-Induced MAP Kinase Signaling Pathway. PloS one. vol 10. issue 11. 2016-06-21. PMID:26536233. |
kp-a159 also dramatically inhibited the expression of marker genes related to osteoclast differentiation, including trap (acp5), cathepsin k (ctsk), dendritic cell-specific transmembrane protein (dcstamp), matrix metallopeptidase 9 (mmp9), and nuclear factor of activated t-cells, cytoplasmic 1 (nfatc1). |
2016-06-21 |
2023-08-13 |
mouse |
| Shaikamjad Umesalma, Frederick Keith Houwen, Gary L Baumbach, Siu-Lung Cha. Roles of Caveolin-1 in Angiotensin II-Induced Hypertrophy and Inward Remodeling of Cerebral Pial Arterioles. Hypertension (Dallas, Tex. : 1979). vol 67. issue 3. 2016-06-21. PMID:26831194. |
in this study, we examined the effects of cav-1 and matrix metalloproteinase-9 (mmp9) on ang ii-mediated structural changes in pial arterioles. |
2016-06-21 |
2023-08-13 |
mouse |
| Nagaraja Tirumuru, Carla D Pretto, Luiza A Castro Jorge, Katherine R Spindle. Mouse Adenovirus Type 1 Early Region 1A Effects on the Blood-Brain Barrier. mSphere. vol 1. issue 2. 2016-06-15. PMID:27303733. |
both wt and e1a mutant virus infection of mice led to similar increases in the activity of two matrix metalloproteinases known to correlate with bbb disruption, mmp2 and mmp9, while causing no increase in the steady-state expression of mmp2 or mmp9 mrna. |
2016-06-15 |
2023-08-13 |
mouse |
| K J Thornton, E Kamange-Sollo, M E White, W R Dayto. Role of G protein-coupled receptors (GPCR), matrix metalloproteinases 2 and 9 (MMP2 and MMP9), heparin-binding epidermal growth factor-like growth factor (hbEGF), epidermal growth factor receptor (EGFR), erbB2, and insulin-like growth factor 1 receptor (IGF-1R) in trenbolone acetate-stimulated bovine satellite cell proliferation. Journal of animal science. vol 93. issue 9. 2016-06-14. PMID:26440329. |
role of g protein-coupled receptors (gpcr), matrix metalloproteinases 2 and 9 (mmp2 and mmp9), heparin-binding epidermal growth factor-like growth factor (hbegf), epidermal growth factor receptor (egfr), erbb2, and insulin-like growth factor 1 receptor (igf-1r) in trenbolone acetate-stimulated bovine satellite cell proliferation. |
2016-06-14 |
2023-08-13 |
cattle |
| K J Thornton, E Kamange-Sollo, M E White, W R Dayto. Role of G protein-coupled receptors (GPCR), matrix metalloproteinases 2 and 9 (MMP2 and MMP9), heparin-binding epidermal growth factor-like growth factor (hbEGF), epidermal growth factor receptor (EGFR), erbB2, and insulin-like growth factor 1 receptor (IGF-1R) in trenbolone acetate-stimulated bovine satellite cell proliferation. Journal of animal science. vol 93. issue 9. 2016-06-14. PMID:26440329. |
the classical genomic actions of testosterone have been well characterized; however, our results indicate that tba may also initiate a quicker, nongenomic response that involves activation of g protein-coupled receptors (gpcr) resulting in activation of matrix metalloproteinases 2 and 9 (mmp2 and mmp9) that release membrane-bound heparin-binding epidermal growth factor-like growth factor (hbegf), which then binds to and activates the epidermal growth factor receptor (egfr) and/or erbb2. |
2016-06-14 |
2023-08-13 |
cattle |
| Qinghua Liu, Donghui Pan, Chao Cheng, Dazhi Zhang, Anyu Zhang, Lizhen Wang, Hongdie Jiang, Tao Wang, Hongrui Liu, Yuping Xu, Runlin Yang, Fei Chen, Min Yang, Changjing Zu. Development of a Novel PET Tracer [18F]AlF-NOTA-C6 Targeting MMP2 for Tumor Imaging. PloS one. vol 10. issue 11. 2016-06-13. PMID:26540114. |
the overexpression of gelatinases, that is, matrix metalloproteinase mmp2 and mmp9, has been associated with tumor progression, invasion, and metastasis. |
2016-06-13 |
2023-08-13 |
Not clear |
| Shi-huan Yu, Li-jie Liu, Bin Lv, Chun-li Che, Da-ping Fan, Li-feng Wang, Yi-mei Zhan. Inhibition of bleomycin-induced pulmonary fibrosis by bone marrow-derived mesenchymal stem cells might be mediated by decreasing MMP9, TIMP-1, INF-γ and TGF-β. Cell biochemistry and function. vol 33. issue 6. 2016-06-09. PMID:26178702. |
matrix metalloproteinase (mmp9), tissue inhibitor of metalloproteinase-1 (timp-1), γ-interferon (inf-γ) and transforming growth factor β1 (tgf-β) were detected in both lung tissue and serum. |
2016-06-09 |
2023-08-13 |
mouse |
| Yanfen Zou, Xiang Yu, Jing Lu, Ziyan Jiang, Qing Zuo, Mingsong Fan, Shiyun Huang, Lizhou Su. Decorin-Mediated Inhibition of Human Trophoblast Cells Proliferation, Migration, and Invasion and Promotion of Apoptosis In Vitro. BioMed research international. vol 2015. 2016-06-09. PMID:26357650. |
also the modulations of decorin on trophoblast cells' metastasis and invasion functions were detected through regulating the matrix metalloproteinases (mmp2 and mmp9). |
2016-06-09 |
2023-08-13 |
human |
| Canan Cakir Aktas, N Dilara Zeybek, A Kevser Piski. In vitro effects of phenytoin and DAPT on MDA-MB-231 breast cancer cells. Acta biochimica et biophysica Sinica. vol 47. issue 9. 2016-06-08. PMID:26206582. |
in order to determine the individual and combined effects of these inhibitors, the 4-[3-(4-iyodophenyl)-2-(4-nitrophenyl)-2h-5-tetrazolio]-1,3-benzene disulfonate (wst-1) test, wound healing assay, and zymography were performed to detect the proliferation, lateral motility, and matrix metalloproteinase-9 (mmp9) activity, respectively. |
2016-06-08 |
2023-08-13 |
Not clear |
| Wei-Chiao Chang, Shuo-Lun Wu, Wan-Chen Huang, Jinn-Yuan Hsu, Shih-Hung Chan, Ju-Ming Wang, Jhih-Peng Tsai, Ben-Kuen Che. PTX3 gene activation in EGF-induced head and neck cancer cell metastasis. Oncotarget. vol 6. issue 10. 2016-05-26. PMID:25797258. |
in addition, fibronectin, matrix metalloproteinase-9 (mmp9) and e-cadherin were essential components in egfr/ptx3-mediated cancer metastasis. |
2016-05-26 |
2023-08-13 |
Not clear |
| Sung Ae Koh, Kyung Hee Le. HGF mediated upregulation of lipocalin 2 regulates MMP9 through nuclear factor-κB activation. Oncology reports. vol 34. issue 4. 2016-05-24. PMID:26259977. |
lipocalin 2 (lcn2) is a member of lipocalin family that binds and transports a small lipophilic ligand, sharing a highly conserved tertiary structure and can be found as a monomer, homodimer, heterodimer with matrix metalloproteinase 9 (mmp9). |
2016-05-24 |
2023-08-13 |
Not clear |
| Kun Liu, Qing Zhang, Haitao Lan, Liping Wang, Pengfei Mou, Wei Shao, Dan Liu, Wensheng Yang, Zhen Lin, Qingyuan Lin, Tianhai J. GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling Pathways. International journal of molecular sciences. vol 16. issue 9. 2016-05-24. PMID:26378521. |
in the present study, we firstly reported that gcn5 was frequently overexpressed in human glioma tissues and gcn5 was positively correlated with proliferation of cell nuclear antigen pcna and matrix metallopeptidase mmp9. |
2016-05-24 |
2023-08-13 |
human |
| Erin L Ealba, Andrew H Jheon, Jane Hall, Camille Curantz, Kristin D Butcher, Richard A Schneide. Neural crest-mediated bone resorption is a determinant of species-specific jaw length. Developmental biology. vol 408. issue 1. 2016-05-23. PMID:26449912. |
we compare jaw development in short-beaked quail versus long-billed duck and find that quail have substantially higher levels of enzymes expressed by bone-resorbing cells including tartrate-resistant acid phosphatase (trap), matrix metalloproteinase 13 (mmp13), and mmp9. |
2016-05-23 |
2023-08-13 |
Not clear |
| Jui-Tai Chen, Tyng-Guey Chen, Yung-Chia Chang, Cheng-Yu Chen, Ruei-Ming Che. Roles of NMDARs in maintenance of the mouse cerebrovascular endothelial cell-constructed tight junction barrier. Toxicology. vol 339. 2016-05-23. PMID:26655082. |
interestingly, amounts of matrix metalloproteinase (mmp)2 and mmp9 in mcecs were augmented by nmda. |
2016-05-23 |
2023-08-13 |
mouse |
| Ujjal K Bhawal, Hye-Jin Lee, Kazumune Arikawa, Michiharu Shimosaka, Masatoshi Suzuki, Toshizo Toyama, Takenori Sato, Ryota Kawamata, Chieko Taguchi, Nobushiro Hamada, Ikuo Nasu, Hirohisa Arakawa, Koh Shibutan. Micromolar sodium fluoride mediates anti-osteoclastogenesis in Porphyromonas gingivalis-induced alveolar bone loss. International journal of oral science. vol 7. issue 4. 2016-05-19. PMID:26674426. |
that effect was accompanied by decreased levels of cathepsin k, interleukin (il)-1β, matrix metalloproteinase 9 (mmp9), and tartrate-resistant acid phosphatase, which were up-regulated during p. gingivalis-induced osteoclastogenesis. |
2016-05-19 |
2023-08-13 |
Not clear |
| Makoto Goto, Junji Chiba, Masaaki Matsuura, Sachiko Iwaki-Egawa, Yasuhiro Watanab. Inflammageing assessed by MMP9 in normal Japanese individuals and the patients with Werner syndrome. Intractable & rare diseases research. vol 5. issue 2. 2016-05-19. PMID:27195193. |
to further study the minor inflammatory condition associated with ageing, another possible ageing biomarker: matrix metalloproteinase-9 (mmp9) was examined in the sera from 217 normal japanese individuals aged between 1 and 100 years and 41 mutation-proven japanese ws aged between 32 and 70 years. |
2016-05-19 |
2023-08-13 |
human |