| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexander S Bayden, Edwin F Gomez, Joseph Audie, Dhruva K Chakravorty, David J Dille. A combined cheminformatic and bioinformatic approach to address the proteolytic stability challenge in peptide-based drug discovery. Biopolymers. vol 104. issue 6. 2016-11-07. PMID:26270398. |
we have created models to predict cleavage sites for several human proteases including caspase-1, caspase-3, caspase-6, caspase-7, cathepsin b, cathepsin d, cathepsin g, cathepsin k, cathepsin l, elastase-2, granzyme a, granzyme b, matrix metallopeptidase-2 (mmp2), mmp7, mmp9, thrombin, and trypsin-1. |
2016-11-07 |
2023-08-13 |
human |
| Yoshimitsu Akiyama, Yuki Koda, Sun-Ju Byeon, Shu Shimada, Taketo Nishikawaji, Ayuna Sakamoto, Yingxuan Chen, Kazuyuki Kojima, Tatsuyuki Kawano, Yoshinobu Eishi, Dajun Deng, Woo Ho Kim, Wei-Guo Zhu, Yasuhito Yuasa, Shinji Tanak. Reduced expression of SET7/9, a histone mono-methyltransferase, is associated with gastric cancer progression. Oncotarget. vol 7. issue 4. 2016-11-01. PMID:26701885. |
expression of srek1ip1, pgc and ccdc28b were inhibited in gc cells with set7/9 knockdown, while matrix metalloproteinase genes (mmp1, mmp7 and mmp9) were activated. |
2016-11-01 |
2023-08-13 |
Not clear |
| Ji-Cheng Tantai, Yao Zhang, Heng Zha. Heterophyllin B inhibits the adhesion and invasion of ECA-109 human esophageal carcinoma cells by targeting PI3K/AKT/β-catenin signaling. Molecular medicine reports. vol 13. issue 2. 2016-10-31. PMID:26647768. |
the mrna and protein expression levels of e-cadherin, vimentin, snail, matrix metalloproteinase (mmp)2 and mmp9 were detected using reverse transcription-quantitative polymerase chain reaction and western blot analyses, respectively. |
2016-10-31 |
2023-08-13 |
human |
| Zixun Dai, Jie Xie, Pengfei Lei, Yihe H. Knockdown of PREX2a inhibits the malignant phenotype of osteosarcoma cells. Molecular medicine reports. vol 13. issue 2. 2016-10-31. PMID:26718453. |
inhibition of prex2a also markedly suppressed the invasion and migration of os cells, at least partly by suppressing the protein expression of matrix metalloproteinase (mmp)2 and mmp9. |
2016-10-31 |
2023-08-13 |
Not clear |
| Cuizhen Zhou, Min Huang, Lijian Xie, Jie Shen, Tingting Xiao, Renjian Wan. IVIG inhibits TNF-α-induced MMP9 expression and activity in monocytes by suppressing NF-κB and P38 MAPK activation. International journal of clinical and experimental pathology. vol 8. issue 12. 2016-10-31. PMID:26884859. |
matrix metalloproteinase-9 (mmp9) has been involved in inflammatory and pathologic processes of coronary artery lesions (cal) in kawasaki disease (kd). |
2016-10-31 |
2023-08-13 |
Not clear |
| Ruijing Tang, Yujun Xu, Feiya Ma, Jing Ren, Sunan Shen, Youwei Du, Yayi Hou, Tingting Wan. Extremely low frequency magnetic fields regulate differentiation of regulatory T cells: Potential role for ROS-mediated inhibition on AKT. Bioelectromagnetics. vol 37. issue 2. 2016-10-28. PMID:26807660. |
compared to the control group, expressions of matrix metalloproteinase (mmp2, mmp9) and forkhead box p3 (foxp3) in lung nodules significantly decreased in the elf-mf group. |
2016-10-28 |
2023-08-13 |
mouse |
| Yi Wang, Jiao-Jiao Zhang, Wei-Rong Yang, Hong-Yan Luo, Jia-Hua Zhang, Xian-Zhong Wan. Lipopolysaccharide-induced expression of FAS ligand in cultured immature boar sertoli cells through the regulation of pro-inflammatory cytokines and miR-187. Molecular reproduction and development. vol 82. issue 11. 2016-10-27. PMID:26256020. |
lps also had no effect on the activity or expression of matrix metalloproteinases 2 or 9 (mmp2 or mmp9). |
2016-10-27 |
2023-08-13 |
Not clear |
| Zhiyu Zhang, Feng Wang, Qin Li, Haifei Zhang, Yan Cui, Chengbin Ma, Jiajun Zhu, Xueyuan Gu, Zhenguo Su. CD151 knockdown inhibits osteosarcoma metastasis through the GSK-3β/β-catenin/MMP9 pathway. Oncology reports. vol 35. issue 3. 2016-10-27. PMID:26707073. |
we further investigated the molecular mechanism of cd151 by inhibiting genes known to be involved in metastasis in os cells and found that cd151 modulated matrix metalloproteinase 9 (mmp9) expression through the glycogen synthase kinase 3 (gsk-3β)/β-catenin signaling pathway. |
2016-10-27 |
2023-08-13 |
Not clear |
| Bo Peng, Hua Zhu, Christian Klausen, Liyang Ma, Yan-Ling Wang, Peter C K Leun. GnRH regulates trophoblast invasion via RUNX2-mediated MMP2/9 expression. Molecular human reproduction. vol 22. issue 2. 2016-10-19. PMID:26660506. |
we hypothesized that runt-related transcription factor 2 (runx2), matrix metalloproteinase (mmp)2 and mmp9 are involved in basal and gonadotrophin-releasing hormone (gnrh)-induced human extravillous trophoblast (evt) cell invasion. |
2016-10-19 |
2023-08-13 |
human |
| Dongfan Li, Xusheng Du, An Liu, Peng L. Suppression of nucleosome-binding protein 1 by miR-326 impedes cell proliferation and invasion in non-small cell lung cancer cells. Oncology reports. vol 35. issue 2. 2016-10-17. PMID:26548724. |
furthermore, suppression of nsbp1 by nsbp1 sirna or mir‑326 overexpression remarkably repressed the expression of cyclin b1 and matrix metalloproteinase 9 (mmp9), which are associated with cancer cell proliferation and invasion. |
2016-10-17 |
2023-08-13 |
human |
| Amir Kiani, Khadijeh Almasi, Yalda Shokoohinia, Komail Sadrjavadi, Amin Nowroozi, Mohsen Shahlae. Combined spectroscopy and molecular modeling studies on the binding of galbanic acid and MMP9. International journal of biological macromolecules. vol 81. 2016-10-13. PMID:26253511. |
the molecular mechanism of galbanic acid (gba) binding to matrix metalloproteinase 9 (mmp9) was investigated by fluorescence quenching, absorption spectroscopy, ft-ir, molecular docking and molecular dynamics (md) simulation procedures. |
2016-10-13 |
2023-08-13 |
Not clear |
| Chenggui Xu, Zhibin Huang, Lijuan Liu, Chufan Luo, Guihua Lu, Qinglang Li, Xiuren Ga. Zinc Regulates Lipid Metabolism and MMPs Expression in Lipid Disturbance Rabbits. Biological trace element research. vol 168. issue 2. 2016-10-12. PMID:25987270. |
since matrix metalloprotease 2 (mmp2) and matrix metalloprotease 9 (mmp9)'s expressions are changed under many pathological conditions, we would like to know how zinc affects lipid metabolism and mmp2, mmp9's expressions in the lipid disturbance rabbits. |
2016-10-12 |
2023-08-13 |
Not clear |
| Ayse Bakir, Philippa D Darbr. Effect of aluminium on migration of oestrogen unresponsive MDA-MB-231 human breast cancer cells in culture. Journal of inorganic biochemistry. vol 152. 2016-10-11. PMID:26365320. |
in parallel, al exposure was found to give rise to increased secretion of active matrix metalloproteinase mmp9 as measured by zymography, and increased intracellular levels of activated mmp14 as measured by western immunoblotting. |
2016-10-11 |
2023-08-13 |
human |
| O A Azzam, D A Bassiouny, M S El-Hawary, Z M El Maadawi, R M Sobhi, M S El-Mesid. Treatment of hypertrophic scars and keloids by fractional carbon dioxide laser: a clinical, histological, and immunohistochemical study. Lasers in medical science. vol 31. issue 1. 2016-10-10. PMID:26498451. |
the aim of the present study was the assessment of the clinical response as well as histological changes in k and hts treated by fractional co2 laser and the role of matrix metalloproteinase 9 (mmp9) in the response. |
2016-10-10 |
2023-08-13 |
Not clear |
| Federica Quattrone, Ana Maria Sanchez, Maria Pannese, Teresa Hemmerle, Paola Viganò, Massimo Candiani, Felice Petraglia, Dario Neri, Paola Panina-Bordigno. The Targeted Delivery of Interleukin 4 Inhibits Development of Endometriotic Lesions in a Mouse Model. Reproductive sciences (Thousand Oaks, Calif.). vol 22. issue 9. 2016-10-05. PMID:25850899. |
expression of genes involved in cell adhesion, extracellular matrix invasion, and neovascularization was significantly downregulated in f8-il4-treated mice compared to their controls (integrin β1: p = .02; metalloproteinase [mmp] 3: p = .02; mmp9: p = .04; vascular endothelial growth factor: p = .04). |
2016-10-05 |
2023-08-13 |
mouse |
| Sonia DaSilva-Arnold, Joanna L James, Abdulla Al-Khan, Stacy Zamudio, Nicholas P Illsle. Differentiation of first trimester cytotrophoblast to extravillous trophoblast involves an epithelial-mesenchymal transition. Placenta. vol 36. issue 12. 2016-10-05. PMID:26545962. |
another 30 genes were up-regulated in evt compared to ctb including mesenchymal markers such as vimentin (235-fold) and fibronectin (107-fold) as well as the matrix metalloproteinases, mmp2 and mmp9 (357-fold, 129-fold). |
2016-10-05 |
2023-08-13 |
Not clear |
| Hyeon-Son Choi, Eu Ddeum Park, Yooheon Park, Hyung Joo Su. Spent coffee ground extract suppresses ultraviolet B-induced photoaging in hairless mice. Journal of photochemistry and photobiology. B, Biology. vol 153. 2016-09-28. PMID:26410040. |
these results were supported by down-regulation of collagen-degrading matrix metalloproteinase 2 (mmp2) and 9 (mmp9) expressions. |
2016-09-28 |
2023-08-13 |
mouse |
| Rongzi Shan, Joanna Szmydynger-Chodobska, Otis U Warren, Farah Mohammad, Brian J Zink, Adam Chodobsk. A New Panel of Blood Biomarkers for the Diagnosis of Mild Traumatic Brain Injury/Concussion in Adults. Journal of neurotrauma. vol 33. issue 1. 2016-09-27. PMID:25794137. |
four candidate biomarkers were identified: copeptin; galectin 3 (lgals3); matrix metalloproteinase 9 (mmp9); and occludin (ocln). |
2016-09-27 |
2023-08-13 |
human |
| Yun Luo, Qi-Wei Jiang, Jie-Ying Wu, Jian-Ge Qiu, Wen-Ji Zhang, Xiao-Long Mei, Zhi Shi, Jin-Ming D. Regulation of migration and invasion by Toll-like receptor-9 signaling network in prostate cancer. Oncotarget. vol 6. issue 26. 2016-09-27. PMID:26087186. |
tlr9 signaling network analysis of the migration and invasion related genes identified several genes, like matrix metallopeptidase 2 (mmp2), matrix metallopeptidase 9 (mmp9), chemokine receptor 4 (cxcr4) and interleukin 8 (il8), formed the core interaction network based on their known biological relationships. |
2016-09-27 |
2023-08-13 |
Not clear |
| Mahesh Sapkota, Liang Li, Hyukjae Choi, William H Gerwick, Yunjo So. Bromo-honaucin A inhibits osteoclastogenic differentiation in RAW 264.7 cells via Akt and ERK signaling pathways. European journal of pharmacology. vol 769. 2016-09-26. PMID:26550952. |
the inhibitory effects on in-vitro osteoclastogenesis was evaluated by counting the number of tartarate resistant acid phospatase (trap) positive multinucleated cells and by measuring the expression level of osteoclast-specific genes like matrix metalloproteinase 9 (mmp9), cathepsin k (cath k), grb2-associated-binding protein 2 (gab2), c-terminal myc kinase (c-myc), c-terminal src kinase (c-src) and microphthalmia-associated transcription factor (mitf). |
2016-09-26 |
2023-08-13 |
Not clear |