| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Varda Lev-Ram, Sakina Palida Lemieux, Thomas J Deerinck, Eric A Bushong, Alex J Perez, Denise R Pritchard, Brandon H Toyama, Sung Kyu R Park, Daniel B McClatchy, Jeffrey N Savas, Michael Whitney, Stephen R Adams, Mark H Ellisman, John Yates, Roger Y Tsie. Do Perineuronal Nets Stabilize the Engram of a Synaptic Circuit? Cells. vol 13. issue 19. 2024-10-15. PMID:39404392. |
preventing pnn erosion by using pharmacological inhibition of pnn-modifying proteases or matrix metalloproteases 9 (mmp9) knockout mice allowed normal fear memory acquisition but diminished long-term memory stabilization, supporting the above hypothesis. |
2024-10-15 |
2024-10-17 |
mouse |
| Peiqiang Liu, Xiaomin Wu, Hao Lv, Jingyu Huang, Tian Gu, Duo Liu, Yu X. Oridonin alleviates cigarette smoke-induced nasal polyp formation by promoting autophagy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 180. 2024-10-15. PMID:39405900. |
following treatment with oridonin, the levels of ova-specific ige, il-6, ifn-γ, il-5, il-13 and il-17a in serum were observed to decrease; the levels of tgf-β1, matrix metalloproteinase 2 (mmp2), mmp7, mmp9 and mmp12 levels in nasal lavage fluid were reduced, while tissue inhibitor of metalloproteinase-1 (timp-1) levels were increased. |
2024-10-15 |
2024-10-18 |
mouse |
| Zhengyuan Li, Lin Hao, Shenghong Chen, Wenhan Fu, Hui Zhang, Zongsheng Yin, Yin Wang, Jun Wan. Forkhead box C1 promotes the pathology of osteoarthritis in subchondral bone osteoblasts via the Piezo1/YAP axis. Cellular signalling. 2024-10-13. PMID:39396563. |
mechanistically, the overexpression of foxc1 through piezo1 activation, in combination with downstream yap signaling, led to increased levels of alkaline phosphatase (alp), collagen type 1 (col1) a1, runx2, osteocalcin, matrix metalloproteinase (mmp) 3, and mmp9 expression. |
2024-10-13 |
2024-10-16 |
mouse |
| Olga V Stepanenko, Maksim I Sulatsky, Ekaterina V Mikhailova, Olesya V Stepanenko, Anna I Sulatskay. Degradation of pathogenic amyloids induced by matrix metalloproteinase-9. International journal of biological macromolecules. 2024-10-12. PMID:39395518. |
this study examines poorly understood effects of an immune enzyme, extracellular matrix metalloproteinase-9 (mmp9), on amyloids associated with alzheimer's and parkinson's diseases, lysozyme, insulin, and dialysis-related amyloidoses. |
2024-10-12 |
2024-10-15 |
Not clear |
| Ming Liu, Hanshu Zhang, Yuanyuan Li, Delan Huang, Huanyan Zuo, Jingwen Yang, Zhi Che. Loss of MMP9 disturbs cranial suture fusion via suppressing cell proliferation, chondrogenesis and osteogenesis in mice. Matrix biology : journal of the International Society for Matrix Biology. 2024-10-07. PMID:39374863. |
mmp9 is a member of the gelatinases that degrades components of the extracellular matrix. |
2024-10-07 |
2024-10-10 |
mouse |
| Tugba Soydas, Guven Yenmis, Matem Tuncdemir, Mustafa Tunaya Kalkan, Elif Yaprak Sarac, Ayhan Bilir, Gonul Kanigur Sultuybe. Metformin represses the carcinogenesis potentially induced by 50 Hz magnetic fields in aged mouse fibroblasts via inhibition of NF-kB. Journal of cellular and molecular medicine. vol 28. issue 19. 2024-10-01. PMID:39350724. |
this in vitro study, therefore, was set out to assess the effects of 5mt mf in 50 hz frequency and met treatment on the viability and proliferation of aged mouse nih/3t3 fibroblasts and expression of rela/p65, matrix metalloproteinases mmp2 and mmp9, and e-cadherin (cdh1) genes. |
2024-10-01 |
2024-10-03 |
mouse |
| Halliru Zailani, Wen-Lung Wang, Senthil Kumaran Satyanarayanan, Wei-Che Chiu, Wen-Chun Liu, Yi-Shan Sung, Jane Pei-Chen Chang, Kuan-Pin S. Omega-3 Polyunsaturated Fatty Acids and Blood-Brain Barrier Integrity in Major Depressive Disorder: Restoring Balance for Neuroinflammation and Neuroprotection. The Yale journal of biology and medicine. vol 97. issue 3. 2024-10-01. PMID:39351324. |
this review examines blood-brain barrier (bbb) dysfunction in mdd, focusing on key regulators like matrix metalloproteinase 9 (mmp9), aquaporin-4 (aqp4), and atp-binding cassette subfamily b member 1 (abcb1). |
2024-10-01 |
2024-10-03 |
Not clear |
| Qiuling Wu, Qilong Zhou, Chengyu Wan, Guang Xin, Tao Wang, Yu Gao, Ting Liu, Xiuxian Yu, Boli Zhang, Wen Huan. Mechanism Actions of Coniferyl Alcohol in Improving Cardiac Dysfunction in Renovascular Hypertension Studied by Experimental Verification and Network Pharmacology. International journal of molecular sciences. vol 25. issue 18. 2024-09-28. PMID:39337549. |
western blot analysis confirmed that ca reduced the expression of il-17, matrix metallopeptidase 9 (mmp9), cyclooxygenase 2 (cox2), and tnf α in heart tissues and the h9c2 cells. |
2024-09-28 |
2024-10-01 |
mouse |
| Reut Meiri, Shay-Lee Aharoni Lotati, Yaron Orenstein, Niv Pap. Deep neural networks for predicting the affinity landscape of protein-protein interactions. iScience. vol 27. issue 9. 2024-09-24. PMID:39310756. |
by inserting an affinity-reducing n-terminal alanine in the n-terminal domain of the tissue inhibitor of metalloproteinases-2 (n-timp2), we overcame the limitation of its narrow affinity range for matrix metalloproteinase 9 (mmp9 |
2024-09-24 |
2024-09-26 |
Not clear |
| Sucheesmita Padhee, Debajani Mohanty, Swagat Mohanty, Ambika Sahoo, Sudipta Jena, Jeetendranath Patnaik, Pratap Chandra Panda, Chitta Ranjan Deb, Asit Ray, Sanghamitra Naya. Identification of the active constituents and molecular mechanism of Eulophia nuda extract in the treatment of osteoarthritis by network pharmacology, molecular modelling and experimental assays. Naunyn-Schmiedeberg's archives of pharmacology. 2024-09-23. PMID:39311920. |
ene exhibited considerable anti-inflammatory effect by reducing pge2, il-6 and il8 levels as well as reducing the mrna expression of matrix metalloproteinases (mmp2 and mmp9). |
2024-09-23 |
2024-09-26 |
Not clear |
| Rui Ding, Xiang-Yang Li, Xiang Wang, Liang Wang, Peng Zhou, Jin-Ling Huan. [Mechanism of Linggui Zhugan Decoction in inhibiting myocardial fibrosis by regulating Wnt/β-catenin pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 15. 2024-09-22. PMID:39307750. |
rt-qpcr was used to detect the gene expression of β-catenin and matrix metalloproteinase 9(mmp9), and immunofluorescence technique was used to detect the expression and localization of key proteins α-sma and β-catenin. |
2024-09-22 |
2024-09-26 |
Not clear |
| Amit Kumar, Da'Kuawn Johnson, Alicia Bukowski, Michael J Noto, Nicholas H Carbonett. IFNλ signaling in neutrophils enhances the pathogenesis of Bordetella pertussis infection. Journal of leukocyte biology. 2024-09-20. PMID:39302155. |
contributing to the differential killing, we found that ifnlr1-/- neutrophils exhibit higher levels of reactive oxygen species, myeloperoxidase [1], matrix metalloproteinase-9 (mmp9) activity, neutrophil extracellular traps (nets), and ifn-γ secretion than wt neutrophils, and inhibiting nadph oxidase inhibited bacterial killing in ifnlr1-/- neutrophils. |
2024-09-20 |
2024-09-22 |
mouse |
| Amena Rezk Mohammed, Wafaa Abdelaziz Emam, Shaymaa A Mohammed, Alshaymaa A Abd Elalim, Eatemad Nabil Abdelhalim Mansour, Haidy Mahmoud Nasr, Aya A Ghamry, Sabah M Alkhawagah, Doaa Sadek Ahmed Fathy, Rasha Sobhy Elattar, Yasser Gaber Ibrahim Abish, Abdullah Hussein, Boshra Ahmed Zaghloul, Marwa K Khairallah, Norah Alharbi, Salwa Seif Eldin, Amal Fahmy Dawood, Marwa A Sabet, Marwa G Gamea, Suzan Eid Elshishtawy Ibrahim, Aliaa A Mosa, Marwa A Dahp. LncRNA ILF3AS1, MMP3, and MMP9 as well as miRNA-212 as emerging novel biomarkers for childhood epilepsy. Frontiers in molecular biosciences. vol 11. 2024-09-14. PMID:39268188. |
interleukin enhancer binding factor 3 antisense rna l (ilf3as1) is a long non-coding rna (lncrna) that enhances the expressions of matrix metalloproteinase 3 (mmp3) and matrix metalloproteinase 9 (mmp9), which are considered to be epileptogenic. |
2024-09-14 |
2024-09-16 |
Not clear |
| Yunbo Jia, Xiaoxi Xu, Yang Liu, Hongfei Shen, Siyu Sun, Guangwei Su. Effect of calcium concentration on metastasis of hepatocellular carcinoma cells cultured in alginate gel beads. Colloids and surfaces. B, Biointerfaces. vol 245. 2024-09-10. PMID:39255748. |
specifically, the expression of activated matrix metalloproteinase 2 (mmp2), matrix metalloproteinase 9 (mmp9), and urokinase-type plasminogen activator system proteins was found to be high. |
2024-09-10 |
2024-09-13 |
Not clear |
| Flobater I Gawargi, Paras K Mishr. MMP9 drives ferroptosis by regulating GPX4 and iron signaling. iScience. vol 27. issue 9. 2024-09-10. PMID:39252956. |
our in-depth research identifies matrix metalloproteinase-9 (mmp9) as a critical modulator of ferroptosis through its influence on gpx4 and iron homeostasis. |
2024-09-10 |
2024-09-13 |
Not clear |
| Helvijs Niedra, Raitis Peculis, Rihards Saksis, Ilona Mandrika, Sofija Vilisova, Jurijs Nazarovs, Austra Breiksa, Aija Gerina, Julie Earl, Ignacio Ruz-Caracuel, Marta Gabriela Rosas, Aldis Pukitis, Natalja Senterjakova, Vita Rovit. Tumor and α-SMA-expressing stromal cells in pancreatic neuroendocrine tumors have a distinct RNA profile depending on tumor grade. Molecular oncology. 2024-09-08. PMID:39245631. |
furthermore, the tumor cells from regions with a rich presence of adjacent α-sma-expressing stromal cells revealed an upregulation of matrix metalloproteinase-9 (mmp9) expression in grade 3 tumors. |
2024-09-08 |
2024-09-11 |
Not clear |
| Zhong Huang, Pengcheng Chen, Yiheng Li. WTAP-mediated m6A modification of circ_0032463 promotes osteosarcoma progression by sponging miR-145-5p and regulating GFRA1 expression. Journal of biochemical and molecular toxicology. vol 38. issue 9. 2024-09-07. PMID:39243199. |
western blot analysis was performed to measure matrix metalloproteinase 2 (mmp2), mmp9, gfra1, and wtap protein levels. |
2024-09-07 |
2024-09-10 |
Not clear |
| Xiaojing Li, Xiujuan Wang, Yongfeng Yang, Jiahui Zhou, Xufei Wu, Jingyuan Zhao, Jianhong Zhang, Xiaoge Guo, Minglong Shao, Meng Song, Xi Su, Yong Han, Qing Liu, Tengfei Chen, Luwen Zhang, Bing Liu, Weihua Yue, Luxian Lv, Wenqiang L. Elevated plasma matrix metalloproteinase 9 in schizophrenia patients associated with poor antipsychotic treatment response and white matter density deficits. Schizophrenia (Heidelberg, Germany). vol 10. issue 1. 2024-08-27. PMID:39191778. |
matrix metalloproteinase 9 (mmp9) is a critical molecular node mediating the interaction between oxidative stress and inflammation, and so may influence treatment efficacy. |
2024-08-27 |
2024-08-30 |
Not clear |
| Yuqin Liu, Ming Nie, Xueyi Li, Hao Wang, Shaoju Ren, Dezheng Zou, Jianhui Liu, Ruidong L. Garlic-derived Exosomes Alleviate Osteoarthritis Through Inhibiting the MAPK Signaling Pathway. Applied biochemistry and biotechnology. 2024-08-27. PMID:39190086. |
chondrocytes were treated with il-1β and incubated with gdes in vitro, and the expression of cartilage matrix components (collagen ii and aggrecan) and matrix degrading enzymes (mmp3 and mmp9) was evaluated via western blotting. |
2024-08-27 |
2024-08-30 |
mouse |
| Kuo-Liang Chiu, Jie-Long He, Guan-Liang Chen, Te-Chun Shen, Li-Hsiou Chen, Jaw-Chyun Chen, Chia-Wen Tsai, Wen-Shin Chang, Te-Chun Hsia, DA-Tian Ba. Impacts of Matrix Metalloproteinase-9 Promoter Genotypes on Asthma Risk. In vivo (Athens, Greece). vol 38. issue 5. 2024-08-26. PMID:39187355. |
the overexpression of matrix metalloproteinase-9 (mmp9) has been observed in asthmatic patients, yet the role of mmp9 genotype in determining asthma susceptibility remains unresolved. |
2024-08-26 |
2024-08-30 |
Not clear |