Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Brad Bolon, Amber Moser, Elizabeth Chlipal. Myelin Methods: A Mini-Review. Toxicologic pathology. 2025-01-20. PMID:39829055. |
some ihc methods reveal enhanced marker expression in damaged myelin (eg, matrix metalloproteinase-9 [mmp9], s100). |
2025-01-20 |
2025-01-23 |
Not clear |
Isha Ranadive, Sonam Patel, Siddharth Pai, Kashmira Khaire, Suresh Balakrishna. Disruption of BMP and FGF signaling prior to blastema formation causes permanent bending and skeletal malformations in Poecilia latipinna tail fin. Zoology (Jena, Germany). vol 168. 2025-01-19. PMID:39827581. |
additionally, ecm remodeling and epithelial-to-mesenchymal transition (emt) were impaired, as shown by reduced matrix metalloproteinases (mmp2 and mmp9), hindering cell migration and blastema stability. |
2025-01-19 |
2025-01-23 |
Not clear |
Rahul Kumar Vempati, Rama Rao Mall. Coralyne Targets the Catalytic Domain of MMP9: An In Silico and In Vitro Investigation. Critical reviews in oncogenesis. vol 30. issue 1. 2025-01-17. PMID:39819436. |
cor reduces the proliferation and migration of breast cancer cells by inhibiting the expression and activity of matrix metalloproteinase 9 (mmp9). |
2025-01-17 |
2025-01-20 |
human |
Fang Fang, Tiange Wu, Mengxue Wang, Wenchao Li, Zonghao You, Ming Chen, Han Gua. Matrix Metalloproteinase-9 is associated with tumor microenvironment remodeling of bladder cancer. Biology direct. vol 20. issue 1. 2025-01-17. PMID:39819701. |
matrix metalloproteinase-9 (mmp9) was identified as a predictive biomarker related to immune microenvironment. |
2025-01-17 |
2025-01-20 |
Not clear |
Xian Tong, Lijuan Xiao, Yanxuan Xi. TFDP1 overexpression promotes apoptosis of nucleus pulposus cells in intervertebral disc degeneration through regulating ADAM15/MMP9 axis. General physiology and biophysics. vol 44. issue 1. 2025-01-16. PMID:39815900. |
western blot or quantitative real-time reverse transcription polymerase chain reaction was applied to assess expressions of tfdp1, matrix metallopeptidase 9 (mmp9), a disintegrin and metalloproteinase 15 (adam15), and apoptosis-associated proteins. |
2025-01-16 |
2025-01-19 |
Not clear |
Satya W Yenny, Jamsari Jamsari, Auliya A Hazmi, Kevin N Cuandra, Wafiq Hanifah, Angela S Yahono, Dhyani P Wahyudi, Gherriandi R Buana, Awalil Rk Rahman, Annisa D Maharani, Muhammad F Firjatullah, Rafi Maulana, Norbertus M Prayogi, Christopher D Trista. In silico analysis of Narra J. vol 4. issue 3. 2025-01-16. PMID:39816070. |
in silico analysis of skin aging is one of the degenerative processes influenced by tyrosinase, elastase, collagenase, hyaluronidase, and matrix metalloproteinase-9 (mmp9) activity. |
2025-01-16 |
2025-01-19 |
Not clear |
Pei-Ping Chen, Qian Wang, Feng-Yu Huang, Xiang-Ying Kong, Na Lin, Xiao-Hui S. [Mechanism of Colquhounia Root Tablets in inhibiting osteoclast differentiation based on HSP90 target modulation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 23. 2025-01-13. PMID:39805785. |
western blot results showed that the expression of hsp90 protein was significantly reduced after intervention with colquhounia root tablets at 20 and 40 μg·ml~(-1)(p<0.01); colquhounia root tablets at 10 μg·ml~(-1) could significantly decrease the expression of necrosis factor receptor associated molecule 6(traf6) and nuclear factor of activated t cells 1(nfatc1) proteins(p<0.01); moreover, all doses of colquhounia root tablets significantly reduced the expression of osteoclast differentiation marker proteins matrix metalloproteinase 9(mmp9) and cathepsin k(ctsk)(p<0.01).immunofluorescence results further confirmed that colquhounia root tablets significantly inhibited hsp90 and ctsk levels, as well as nfatc1 activation in osteoblasts. |
2025-01-13 |
2025-01-16 |
Not clear |
Seyede Nazanin Zarneshan, Elham Arkan, Amir Kiani, Seyede Zahra Hosseini, Fatemeh Abbaszadeh, Sajad Fakhr. Protective effects of polydatin amphiphilic chitosan nanocarriers against an aluminum chloride-induced model of Alzheimer's disease in rats: relevance to its anti-inflammatory and antioxidant effects. Naunyn-Schmiedeberg's archives of pharmacology. 2025-01-09. PMID:39786589. |
npd, as a newly synthesized formulation for pd, potentially improved memory and cognitive behavioral parameters and reduced the activity of inflammatory matrix metalloproteinase 9 (mmp9) and serum nitrite levels, while increasing anti-inflammatory mmp2, antioxidant catalase, and glutathione. |
2025-01-09 |
2025-01-13 |
rat |
Barbara Alves Fonseca, Thaís de Oliveira Fernandes, Dalila Ferreira Silvano de Moura, Caio Luiz Bittencourt Reis, Erika Calvano Küchler, Flares Baratto-Filho, Leonardo Santos Antunes, Lívia Azeredo Alves Antune. Single-Nucleotide Polymorphisms in MMP3, TIMP1, and MTR Genes are Associated With Delayed Deciduous Tooth Eruption. Biochemical genetics. 2025-01-08. PMID:39776370. |
to analyze whether the single-nucleotide polymorphisms (snps) in matrix metalloproteinases 2, 3, and 9 (mmp2, mmp3, and mmp9), tissue inhibitor of metalloproteinases 1 and 2 (timp1 and timp2), methionine synthase (mtr) and methionine synthase reductase (mtrr) influence delayed deciduous tooth eruption (ddte). |
2025-01-08 |
2025-01-13 |
Not clear |
Craig C Ulrich, Lauren L Parker, Janet A Lambert, Lexa Baldwin, Iain L O Buxton, Neda Etezadi-Amoli, Normand Leblanc, Heather R Burki. Matrix Metallopeptidase 9 Promotes Contraction in Human Uterine Myometrium. Reproductive sciences (Thousand Oaks, Calif.). 2025-01-08. PMID:39776427. |
matrix metallopeptidase 9 (mmp9) is a secreted zinc-dependent peptidase known for extracellular remodeling. |
2025-01-08 |
2025-01-13 |
human |
Craig C Ulrich, Lauren L Parker, Janet A Lambert, Lexa Baldwin, Iain L O Buxton, Neda Etezadi-Amoli, Normand Leblanc, Heather R Burki. Matrix Metallopeptidase 9 Promotes Contraction in Human Uterine Myometrium. Reproductive sciences (Thousand Oaks, Calif.). 2025-01-08. PMID:39776427. |
mmp9 is elevated in tissues from women experiencing preterm labor, and previous research has shown that the addition of combined matrix metallopeptidases 2 and 9 (mmp2/9) enhances uterine contractions. |
2025-01-08 |
2025-01-13 |
human |
Sanjeeb Shrestha, Jae-Han Jeon, Chang-Won Hon. Neutrophils in MASLD and MASH. BMB reports. 2025-01-05. PMID:39757200. |
in contrast, neutrophils contribute to liver protection and repair through mechanisms involving microrna-223 and matrix metalloproteinase 9 (mmp9). |
2025-01-05 |
2025-01-08 |
human |
Tao Zhong, Shun Wu, Guolin Chen, Siyuan Zhan, Linjie Wang, Jiaxue Cao, Jiazhong Guo, Li Li, Hongping Zhang, Lili Ni. Integrated analyses of transcriptomes, metabolomes, and proteomes unveil the role of FoXO signaling axis in buck semen cryopreservation. Theriogenology. vol 235. 2025-01-05. PMID:39756112. |
during sperm cryopreservation, the expression level of g protein subunit alpha i3 (gnai3) was significantly downregulated in post-thaw sperm (p < 0.001), while matrix metallopeptidase 9 (mmp9) was upregulated compared to fs groups (p < 0.01). |
2025-01-05 |
2025-01-08 |
cat |
Kate E Foley, Erica M Weekman, Donna M Wilcoc. Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 20 Suppl 1. 2025-01-03. PMID:39751186. |
furthermore, coincident with microhemorrhage occurrence is increased expression and activity of matrix metalloproteinases (mmps) mmp9 and mmp3. |
2025-01-03 |
2025-01-05 |
mouse |
Jun-Xing Zhu, Can Zhou, Lu-Zhe Huang, Jian-Wei Guo, Nian-Pei Yin, Fang Yang, Yu-Da Zhang, Ying Yan. Intervention effect of regulating GABA-A receptor activity on the formation of experimental abdominal aortic aneurysm in rats. Scientific reports. vol 14. issue 1. 2024-12-29. PMID:39732918. |
additionally, topiramate decreases the secretion of matrix metalloproteinases mmp2 and mmp9, thereby inhibiting extracellular matrix degradation and slowing the progression of aneurysms. |
2024-12-29 |
2024-12-31 |
rat |
Zhigang Wang, Longzhi Fang, Meng Han, Kangzhe Liu, Yuanmei Zheng, Yibei Zha. Exploring the mechanism of avenanthramide in the treatment of atherosclerosis based on network pharmacology and molecular docking: An observational study. Medicine. vol 103. issue 51. 2024-12-20. PMID:39705422. |
five pivotal genes, matrix metalloproteinase-9 (mmp9), epidermal growth factor receptor (egfr), icam1, casp3, and mmp2, were selected from the ppi network. |
2024-12-20 |
2024-12-23 |
Not clear |
Mingzhen Tian, Meysam Keshavarz, Ali Anil Demircali, Bing Han, Guang-Zhong Yan. Localized Microrobotic Delivery of Enzyme-Responsive Hydrogel-Immobilized Therapeutics to Suppress Triple-Negative Breast Cancer. Small (Weinheim an der Bergstrasse, Germany). 2024-12-18. PMID:39692188. |
crucially, the drug release mechanism is engineered to be responsive to the tumor microenvironment and is regulated by the overexpression of the enzymatic activity of matrix metalloproteinases (mmp2 and mmp9) in tnbc tumors, triggering the degradation of the hydrogel matrix, leading to controlled release of the immobilized therapeutic drug. |
2024-12-18 |
2024-12-21 |
Not clear |
Xianjie Ai, Xinyu Wang, Taotao Ren, Zhong Li, Bo Wu, Ming L. MMP9 in pan-cancer and computational study to screen for MMP9 inhibitors. American journal of translational research. vol 16. issue 11. 2024-12-16. PMID:39678601. |
the stromal cell protein metalloproteinase 9 (mmp9), associated with extracellular matrix degradation and remodeling, promotes tumor invasion and metastasis and regulates cell adhesion molecule and cytokine activity. |
2024-12-16 |
2024-12-21 |
Not clear |
Amira M Kamel, Mona Moaness, Abeer Salama, Manar M Ahmed, Hanan H Beherei, Mostafa Mabrou. Smart hydrogels for rapid wound repair: Chitosan-PVP matrices empowered by bimetallic MOF nanocages. International journal of biological macromolecules. 2024-12-13. PMID:39672442. |
this rapid healing occurred due to the reduction of inflammation and il-1 content in the dermis; the downregulation of mmp9 halted the breakdown of the extracellular matrix (ecm); the upregulation of tgf accelerated cell growth and raised the levels of collagen 1 and -sma in the ecm. |
2024-12-13 |
2024-12-21 |
Not clear |
Cynthia Rosa Regalado, Mihály Balog. MMP9: Link between neuropathy and colorectal cancer? Frontiers in molecular biosciences. vol 11. 2024-12-12. PMID:39664453. |
this review investigates the role of matrix metalloproteinase 9 (mmp9) in linking crc to neuropathy, aiming to uncover shared mechanisms that could offer new therapeutic targets. |
2024-12-12 |
2024-12-14 |
Not clear |