| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong-Kun Li, Xiao-Chun Chen, Yuan-Gui Zhu, Xiao-Song Peng, Yu-Qi Zeng, Jie Sheng, Tian-Wen Huan. [Ginsenoside Rb1 attenuates okadaic acid-induced Tau protein hyperphosphorylation in rat hippocampal neurons]. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 2. 2012-06-28. PMID:15830099. |
the present study was aimed to investigate the effects of ginsenoside rb1 on okadaic acid (oa)-induced tau hyperphosphorylation in hippocampal neurons of sparague-dawley rat and to explore its possible mechanism. |
2012-06-28 |
2023-08-12 |
rat |
| Yong-Kun Li, Xiao-Chun Chen, Yuan-Gui Zhu, Xiao-Song Peng, Yu-Qi Zeng, Jie Sheng, Tian-Wen Huan. [Ginsenoside Rb1 attenuates okadaic acid-induced Tau protein hyperphosphorylation in rat hippocampal neurons]. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 2. 2012-06-28. PMID:15830099. |
on the thirteen day of pretreatment, animals in rb1 pretreatment group as well as animals in oa group received a bolus injection of 0.483 microg of oa (1.5 microl of solution in dmso) at right dorsal aspect of hippocampus to induce tau hyperphosphrylation. |
2012-06-28 |
2023-08-12 |
rat |
| Yong-Kun Li, Xiao-Chun Chen, Yuan-Gui Zhu, Xiao-Song Peng, Yu-Qi Zeng, Jie Sheng, Tian-Wen Huan. [Ginsenoside Rb1 attenuates okadaic acid-induced Tau protein hyperphosphorylation in rat hippocampal neurons]. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 2. 2012-06-28. PMID:15830099. |
these results indicate that oa-induced hyperphosphorylation of tau protein in rat hippocampal neurons can be attenuated by the pretreatment of ginsenoside rb1. |
2012-06-28 |
2023-08-12 |
rat |
| Qian Chen, Zhou Zhou, Lei Zhang, Yuan Wang, Yan-wen Zhang, Min Zhong, Shang-cheng Xu, Chun-hai Chen, Li Li, Zheng-ping Y. Tau protein is involved in morphological plasticity in hippocampal neurons in response to BDNF. Neurochemistry international. vol 60. issue 3. 2012-06-25. PMID:22226842. |
tau protein is involved in morphological plasticity in hippocampal neurons in response to bdnf. |
2012-06-25 |
2023-08-12 |
rat |
| Qian Chen, Zhou Zhou, Lei Zhang, Yuan Wang, Yan-wen Zhang, Min Zhong, Shang-cheng Xu, Chun-hai Chen, Li Li, Zheng-ping Y. Tau protein is involved in morphological plasticity in hippocampal neurons in response to BDNF. Neurochemistry international. vol 60. issue 3. 2012-06-25. PMID:22226842. |
stimulation of the cultured rat hippocampal neurons with bdnf resulted in increased tau protein expression, as detected by western blotting. |
2012-06-25 |
2023-08-12 |
rat |
| Tohru Matsuki, Mariam Zaka, Rita Guerreiro, Marcel P van der Brug, Jonathan A Cooper, Mark R Cookson, John A Hardy, Brian W Howel. Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice. PloS one. vol 7. issue 2. 2012-06-18. PMID:22355340. |
tau is hyperphosphorylated in the hippocampus of dab1-null mice in a strain-dependent manner; however, it has not been clear if the tau phosphorylation phenotype is a secondary effect of the morbidity of these mutants. |
2012-06-18 |
2023-08-12 |
mouse |
| Sarah M Rothman, Nathan Herdener, Simonetta Camandola, Sarah J Texel, Mohamed R Mughal, Wei-Na Cong, Bronwen Martin, Mark P Mattso. 3xTgAD mice exhibit altered behavior and elevated Aβ after chronic mild social stress. Neurobiology of aging. vol 33. issue 4. 2012-06-15. PMID:21855175. |
a triple-transgenic mouse model of ad (3xtgad mice) and nontransgenic control mice were used to test for an affect of chronic mild social stress on blood glucose, plasma glucocorticoids, plasma insulin, anxiety, and hippocampal amyloid β-particle (aβ), phosphorylated tau (ptau), and brain-derived neurotrophic factor (bdnf) levels. |
2012-06-15 |
2023-08-12 |
mouse |
| Rodolfo Pinto-Almazán, Claudia C Calzada-Mendoza, María G Campos-Lara, Christian Guerra-Araiz. Effect of chronic administration of estradiol, progesterone, and tibolone on the expression and phosphorylation of glycogen synthase kinase-3β and the microtubule-associated protein tau in the hippocampus and cerebellum of female rat. Journal of neuroscience research. vol 90. issue 4. 2012-06-12. PMID:22183707. |
effect of chronic administration of estradiol, progesterone, and tibolone on the expression and phosphorylation of glycogen synthase kinase-3β and the microtubule-associated protein tau in the hippocampus and cerebellum of female rat. |
2012-06-12 |
2023-08-12 |
rat |
| Rodolfo Pinto-Almazán, Claudia C Calzada-Mendoza, María G Campos-Lara, Christian Guerra-Araiz. Effect of chronic administration of estradiol, progesterone, and tibolone on the expression and phosphorylation of glycogen synthase kinase-3β and the microtubule-associated protein tau in the hippocampus and cerebellum of female rat. Journal of neuroscience research. vol 90. issue 4. 2012-06-12. PMID:22183707. |
we studied the effect of chronic administration of estradiol (e2), progesterone (p4), and tibolone (tib) on the expression and phosphorylation of microtubule-associated protein tau and glycogen synthase kinase-3β (gsk3β) in the hippocampus and cerebellum of ovariectomized rats. |
2012-06-12 |
2023-08-12 |
rat |
| Rodolfo Pinto-Almazán, Claudia C Calzada-Mendoza, María G Campos-Lara, Christian Guerra-Araiz. Effect of chronic administration of estradiol, progesterone, and tibolone on the expression and phosphorylation of glycogen synthase kinase-3β and the microtubule-associated protein tau in the hippocampus and cerebellum of female rat. Journal of neuroscience research. vol 90. issue 4. 2012-06-12. PMID:22183707. |
we observed that, in the hippocampus, administration of e2, p4, or tib significantly decreased the protein content of hyperphosphorylated tau and increased the tau dephosphorylated form, whereas only treatment with tib increased the content of the phosphorylated form of gsk3β. |
2012-06-12 |
2023-08-12 |
rat |
| Rodolfo Pinto-Almazán, Claudia C Calzada-Mendoza, María G Campos-Lara, Christian Guerra-Araiz. Effect of chronic administration of estradiol, progesterone, and tibolone on the expression and phosphorylation of glycogen synthase kinase-3β and the microtubule-associated protein tau in the hippocampus and cerebellum of female rat. Journal of neuroscience research. vol 90. issue 4. 2012-06-12. PMID:22183707. |
these results indicate that chronic administration of gonadal hormones and tibolone modulates tau and gsk3β phosphorylation in hippocampus and cerebellum of the rat and may exert a neuroprotective effect in these tissues. |
2012-06-12 |
2023-08-12 |
rat |
| Eun Ji Gong, Hee Ra Park, Mi Eun Kim, Shunfu Piao, Eunjin Lee, Dong-Gyu Jo, Hae Young Chung, Nam-Chul Ha, Mark P Mattson, Jaewon Le. Morin attenuates tau hyperphosphorylation by inhibiting GSK3β. Neurobiology of disease. vol 44. issue 2. 2012-06-11. PMID:21782947. |
furthermore, treatment of 3xtg-ad mice with morin resulted in reductions in tau hyperphosphorylation and paired helical filament-like immunoreactivity in hippocampal neurons. |
2012-06-11 |
2023-08-12 |
mouse |
| Evelin L Schaeffer, Vanessa J De-Paula, Emanuelle R da Silva, Barbara de A Novaes, Heni D Skaf, Orestes V Forlenza, Wagner F Gatta. Inhibition of phospholipase A2 in rat brain decreases the levels of total Tau protein. Journal of neural transmission (Vienna, Austria : 1996). vol 118. issue 9. 2012-06-01. PMID:21387172. |
the aim of this study was to conduct a preliminary investigation into the effects of in vivo infusion of mafp into rat brain on pla(2) activity and total tau levels in the postmortem frontal cortex and dorsal hippocampus. |
2012-06-01 |
2023-08-12 |
human |
| Daowei Lin, Lin Cao, Zhi Wang, Jiejie Li, Jacqueline M Washington, Zhiyi Zu. Lidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats. Behavioural brain research. vol 228. issue 2. 2012-05-23. PMID:22192381. |
isoflurane and lidocaine did not affect the amount of β-amyloid peptide, total tau and phospho-tau in the cerebral cortex as well as interleukin-1β and tumor necrosis factor-α in the hippocampus at 29 days after isoflurane exposure. |
2012-05-23 |
2023-08-12 |
rat |
| Thomas van Groen, Inga Kadish, Natalija Popović, Miroljub Popović, María Caballero-Bleda, Beatriz Baño-Otálora, Pablo Vivanco, María Ángeles Rol, Juan Antonio Madri. Age-related brain pathology in Octodon degu: blood vessel, white matter and Alzheimer-like pathology. Neurobiology of aging. vol 32. issue 9. 2012-05-17. PMID:19910078. |
significant amounts of aβ and tau deposits are present in the hippocampal formation of 6-year-old o. degus, primarily in the white matter, but these hippocampal aβ and tau deposits are not present in younger ones. |
2012-05-17 |
2023-08-12 |
Not clear |
| Thomas van Groen, Inga Kadish, Natalija Popović, Miroljub Popović, María Caballero-Bleda, Beatriz Baño-Otálora, Pablo Vivanco, María Ángeles Rol, Juan Antonio Madri. Age-related brain pathology in Octodon degu: blood vessel, white matter and Alzheimer-like pathology. Neurobiology of aging. vol 32. issue 9. 2012-05-17. PMID:19910078. |
the tau deposits in the hippocampal formation coincide with a significant decrease in staining for myelin in the same areas, indicating hippocampal disconnection and, likely, dysfunction. |
2012-05-17 |
2023-08-12 |
Not clear |
| Heinz-Georg Jahnke, Annett Braesigk, Till G A Mack, Sarah Pönick, Frank Striggow, Andrea A Robitzk. Impedance spectroscopy based measurement system for quantitative and label-free real-time monitoring of tauopathy in hippocampal slice cultures. Biosensors & bioelectronics. vol 32. issue 1. 2012-05-14. PMID:22221799. |
we induced tau hyperphosphorylation in organotypic hippocampal slice cultures (ohsc) and applied marker-independent real-time electrical impedance spectroscopy (eis) for cellular real-time pathology monitoring. |
2012-05-14 |
2023-08-12 |
Not clear |
| Bo Cui, Mingquan Wu, Xiaojun She, Hongtao Li. Impulse noise exposure in rats causes cognitive deficits and changes in hippocampal neurotransmitter signaling and tau phosphorylation. Brain research. vol 1427. 2012-05-11. PMID:22055774. |
impulse noise exposure in rats causes cognitive deficits and changes in hippocampal neurotransmitter signaling and tau phosphorylation. |
2012-05-11 |
2023-08-12 |
rat |
| Bo Cui, Mingquan Wu, Xiaojun She, Hongtao Li. Impulse noise exposure in rats causes cognitive deficits and changes in hippocampal neurotransmitter signaling and tau phosphorylation. Brain research. vol 1427. 2012-05-11. PMID:22055774. |
effects of noise on the glutamate (glu)-n-methyl-d-aspartic acid receptor (nmdar) signaling system and hippocampal tau phosphorylation were investigated by high performance liquid chromatography, western blotting, and immunohistochemistry. |
2012-05-11 |
2023-08-12 |
rat |
| Bo Cui, Mingquan Wu, Xiaojun She, Hongtao Li. Impulse noise exposure in rats causes cognitive deficits and changes in hippocampal neurotransmitter signaling and tau phosphorylation. Brain research. vol 1427. 2012-05-11. PMID:22055774. |
impulse noise stress also caused a significant increase in nmdar 2b subunit (nr2b) expression and a two-phase increase in tau phosphorylation in hippocampus. |
2012-05-11 |
2023-08-12 |
rat |