| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhihui Gai, Donghong Su, Yawen Wang, Wenlong Li, Bo Cui, Kang Li, Xiaojun She, Rui Wan. Effects of chronic noise on the corticotropin-releasing factor system in the rat hippocampus: relevance to Alzheimer's disease-like tau hyperphosphorylation. Environmental health and preventive medicine. vol 22. issue 1. 2018-09-04. PMID:29228900. |
effects of chronic noise on the corticotropin-releasing factor system in the rat hippocampus: relevance to alzheimer's disease-like tau hyperphosphorylation. |
2018-09-04 |
2023-08-13 |
rat |
| Zhihui Gai, Donghong Su, Yawen Wang, Wenlong Li, Bo Cui, Kang Li, Xiaojun She, Rui Wan. Effects of chronic noise on the corticotropin-releasing factor system in the rat hippocampus: relevance to Alzheimer's disease-like tau hyperphosphorylation. Environmental health and preventive medicine. vol 22. issue 1. 2018-09-04. PMID:29228900. |
in this study, we explored the effects of long-term noise exposure on the corticotropin-releasing factor (crf) system in the hippocampus and its role in noise-induced tau phosphorylation. |
2018-09-04 |
2023-08-13 |
rat |
| Gabor G Kovacs, Linda K Kwong, Murray Grossman, David J Irwin, Edward B Lee, John L Robinson, Eunran Suh, Vivianna M Van Deerlin, Virginia M Lee, John Q Trojanowsk. Tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases. Brain pathology (Zurich, Switzerland). vol 28. issue 2. 2018-08-30. PMID:28019685. |
tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases. |
2018-08-30 |
2023-08-13 |
human |
| Gabor G Kovacs, Linda K Kwong, Murray Grossman, David J Irwin, Edward B Lee, John L Robinson, Eunran Suh, Vivianna M Van Deerlin, Virginia M Lee, John Q Trojanowsk. Tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases. Brain pathology (Zurich, Switzerland). vol 28. issue 2. 2018-08-30. PMID:28019685. |
common neuropathological features included neuronal loss in the hippocampus and dentate gyrus associated with spherical basophilic pick body-like inclusions showing 4r tau immunoreactivity, which was supported by the detection of predominantly 4r tau species by western blot examination. |
2018-08-30 |
2023-08-13 |
human |
| Gabor G Kovacs, Linda K Kwong, Murray Grossman, David J Irwin, Edward B Lee, John L Robinson, Eunran Suh, Vivianna M Van Deerlin, Virginia M Lee, John Q Trojanowsk. Tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases. Brain pathology (Zurich, Switzerland). vol 28. issue 2. 2018-08-30. PMID:28019685. |
in addition, accumulation of tau immunoreactive argyrophilic astrocytes in the hippocampus and amygdala and oligodendroglial coiled bodies in the hippocampal white matter were observed. |
2018-08-30 |
2023-08-13 |
human |
| Gabor G Kovacs, Linda K Kwong, Murray Grossman, David J Irwin, Edward B Lee, John L Robinson, Eunran Suh, Vivianna M Van Deerlin, Virginia M Lee, John Q Trojanowsk. Tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases. Brain pathology (Zurich, Switzerland). vol 28. issue 2. 2018-08-30. PMID:28019685. |
we suggest that this tauopathy variant with hippocampal 4r tau immunoreactive spherical inclusions might contribute to the cognitive deficits in the patients reported here. |
2018-08-30 |
2023-08-13 |
human |
| Anaclara Prada Jardim, Joan Liu, Jack Baber, Zuzanna Michalak, Cheryl Reeves, Matthew Ellis, Jan Novy, Jane de Tisi, Andrew McEvoy, Anna Miserocchi, Elza Marcia Targas Yacubian, Sanjay Sisodiya, Pamela Thompson, Maria Tho. Characterising subtypes of hippocampal sclerosis and reorganization: correlation with pre and postoperative memory deficit. Brain pathology (Zurich, Switzerland). vol 28. issue 2. 2018-08-30. PMID:28380661. |
we also evaluated hippocampal regenerative activity (mcm2, nestin, olig2, calbindin), degeneration (at8/phosphorylated tau) and mossy-fiber pathway re-organization (znt3). |
2018-08-30 |
2023-08-13 |
Not clear |
| Tong Li, Kerstin E Braunstein, Juhong Zhang, Ashley Lau, Leslie Sibener, Christopher Deeble, Philip C Won. The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model. Nature communications. vol 7. 2018-08-27. PMID:27373369. |
we show that this tau fragment seeds the neuritic plaque-dependent pathological conversion of wild-type tau that spreads from the cortex and hippocampus to the brain stem. |
2018-08-27 |
2023-08-13 |
mouse |
| Miho Uematsu, Ayako Nakamura, Momoko Ebashi, Katsuiku Hirokawa, Ryosuke Takahashi, Toshiki Uchihar. Brainstem tau pathology in Alzheimer's disease is characterized by increase of three repeat tau and independent of amyloid\\xc2\\xa0\\xce\\xb2. Acta neuropathologica communications. vol 6. issue 1. 2018-08-20. PMID:29298724. |
in the hippocampus, the number of nfts, and the proportion of 3r tau progressively increases. |
2018-08-20 |
2023-08-13 |
Not clear |
| Qing-Hua Ma, Liu-Fang Jiang, Jian-Liang Mao, Wen-Xin Xu, Min Huan. Vildagliptin prevents cognitive deficits and neuronal apoptosis in a rat model of Alzheimer's disease. Molecular medicine reports. vol 17. issue 3. 2018-08-15. PMID:29257340. |
these results indicate that vildagliptin administration exerts a protective effect against cognitive deficits by reducing tau phosphorylation and increasing the expression of proteins associated with synaptic plasticity in the hippocampus. |
2018-08-15 |
2023-08-13 |
rat |
| Melike Yuksel, Kevser Biberoglu, Seda Onder, K Gonca Akbulut, Ozden Taca. Toluidine blue O modifies hippocampal amyloid pathology in a transgenic mouse model of Alzheimer's disease. Biochimie. vol 146. 2018-08-13. PMID:29248542. |
similarly, tbo did not recover hyperphosphorylation of tau at residues thr181 and ser202/thr205 significantly in soluble and insoluble hippocampal fractions of 3xtg-ad mice. |
2018-08-13 |
2023-08-13 |
mouse |
| M Bol\\xc3\\xb3s, N Pallas-Bazarra, J Terreros-Roncal, J R Perea, J Jurado-Arjona, J \\xc3\\x81vila, M Llorens-Mart\\xc3\\xad. Soluble Tau has devastating effects on the structural plasticity of hippocampal granule neurons. Translational psychiatry. vol 7. issue 12. 2018-07-30. PMID:29217824. |
soluble tau has devastating effects on the structural plasticity of hippocampal granule neurons. |
2018-07-30 |
2023-08-13 |
mouse |
| M Bol\\xc3\\xb3s, N Pallas-Bazarra, J Terreros-Roncal, J R Perea, J Jurado-Arjona, J \\xc3\\x81vila, M Llorens-Mart\\xc3\\xad. Soluble Tau has devastating effects on the structural plasticity of hippocampal granule neurons. Translational psychiatry. vol 7. issue 12. 2018-07-30. PMID:29217824. |
here we evaluated the long-term impact of a single stereotaxic injection of human soluble tau on hippocampal granule neurons in mice. |
2018-07-30 |
2023-08-13 |
mouse |
| Satoshi Okuyama, Yoshimi Kotani, Kana Yamamoto, Atsushi Sawamoto, Kuniaki Sugawara, Masahiko Sudo, Yuu Ohkubo, Arisa Tamanaha, Mitsunari Nakajima, Yoshiko Furukaw. The peel of Citrus kawachiensis (kawachi bankan) ameliorates microglial activation, tau hyper-phosphorylation, and suppression of neurogenesis in the hippocampus of senescence-accelerated mice. Bioscience, biotechnology, and biochemistry. vol 82. issue 5. 2018-07-30. PMID:29424280. |
the peel of citrus kawachiensis (kawachi bankan) ameliorates microglial activation, tau hyper-phosphorylation, and suppression of neurogenesis in the hippocampus of senescence-accelerated mice. |
2018-07-30 |
2023-08-13 |
mouse |
| Satoshi Okuyama, Yoshimi Kotani, Kana Yamamoto, Atsushi Sawamoto, Kuniaki Sugawara, Masahiko Sudo, Yuu Ohkubo, Arisa Tamanaha, Mitsunari Nakajima, Yoshiko Furukaw. The peel of Citrus kawachiensis (kawachi bankan) ameliorates microglial activation, tau hyper-phosphorylation, and suppression of neurogenesis in the hippocampus of senescence-accelerated mice. Bioscience, biotechnology, and biochemistry. vol 82. issue 5. 2018-07-30. PMID:29424280. |
the c. kawachiensis treatment inhibited microglial activation in the hippocampus, the hyper-phosphorylation of tau at 231 of threonine in hippocampal neurons, and ameliorated the suppression of neurogenesis in the dentate gyrus of the hippocampus. |
2018-07-30 |
2023-08-13 |
mouse |
| Chunyan Zhu, Bing Xu, Xiaohong Sun, Qiwen Zhu, Yi Su. Targeting CCR3 to Reduce Amyloid-\\xce\\xb2 Production, Tau Hyperphosphorylation, and Synaptic Loss in a Mouse Model of Alzheimer's Disease. Molecular neurobiology. vol 54. issue 10. 2018-07-27. PMID:27878757. |
in the present study, we showed that ccr3, the receptor for ccl11, was expressed by hippocampal neurons and treatment of primary hippocampal neuronal cultures (14\xc2\xa0days in vitro) with ccl11 resulted in activation of cyclin-dependent kinase 5 and glycogen synthase kinase-3\xce\xb2, associated with elevated tau phosphorylation at multiple sites. |
2018-07-27 |
2023-08-13 |
mouse |
| Huan Zhou, Ying Guo, Xing Li, Zheng-Yu Liuyang, Yang-Ping Shentu, Xiao-Peng Jing, Jia-Wei Liang, Xin-Wen Zhou, Xiao-Chuan Wang, Jian-Zhi Wang, Ji Zeng, Rong Li. Long-term Helicobacter pylori infection does not induce tauopathy and memory impairment in SD rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 37. issue 6. 2018-07-26. PMID:29270738. |
however, there was no significant change of tau phosphorylation at thr205 (pt205), thr231 (pt231), ser396 (ps396) and ser404 (ps404) sites in the hippocampus and cerebral cortex. |
2018-07-26 |
2023-08-13 |
human |
| S L Angulo, R Orman, S A Neymotin, L Liu, L Buitrago, E Cepeda-Prado, D Stefanov, W W Lytton, M Stewart, S A Small, K E Duff, H Moren. Tau and amyloid-related pathologies in the entorhinal cortex have divergent effects in the hippocampal circuit. Neurobiology of disease. vol 108. 2018-07-23. PMID:28860088. |
tau and amyloid-related pathologies in the entorhinal cortex have divergent effects in the hippocampal circuit. |
2018-07-23 |
2023-08-13 |
mouse |
| Miranda Tuwaig, M\\xc3\\xa9lissa Savard, Beno\\xc3\\xaet Jutras, Judes Poirier, D Louis Collins, Pedro Rosa-Neto, David Fontaine, John C S Breitne. Deficit in Central Auditory Processing as a Biomarker of Pre-Clinical Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 60. issue 4. 2018-07-23. PMID:28984583. |
adjusting for age, sex, education, pure-tone hearing, and apoe\xc9\x9b4 status, we observed a persistent relationship between cap scores and csf tau levels, entorhinal and hippocampal cortex volumes, cortical thickness, and deficits in cognition (repeatable battery for assessment of neuropsychological status total score, and several of its index scales). |
2018-07-23 |
2023-08-13 |
Not clear |
| Zhong-Hong Kong, Xin Chen, Hui-Po Hua, Liang Liang, Long-Juan Li. The Oral Pretreatment of Glycyrrhizin Prevents Surgery-Induced Cognitive Impairment in Aged Mice by Reducing Neuroinflammation and Alzheimer's-Related Pathology via HMGB1 Inhibition. Journal of molecular neuroscience : MN. vol 63. issue 3-4. 2018-07-20. PMID:29034441. |
additionally, the pretreatment of glycyrrhizin reduced the postoperative neuroinflammation (production of pro-inflammatory cytokines including il-1\xce\xb2, tnf-\xce\xb1, and il-6 as well as nf-\xce\xbab nuclear expression) and alzheimer's-related pathology (tau phosphorylation at the site of at-8 and ser396 as well as a\xce\xb240 and 42 concentrations) in the hippocampus of the aged mice undergoing splenectomy surgery. |
2018-07-20 |
2023-08-13 |
mouse |