| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hai-Hong Wang, Yan Li, Ang Li, Fang Yan, Zhen-Lin Li, Zhong-Ying Liu, Lei Zhang, Jian Zhang, Wei-Ren Dong, Lin Zhan. Erratum to: Forskolin Induces Hyperphosphorylation of Tau Accompanied by Cell Cycle Reactivation in Primary Hippocampal Neurons. Molecular neurobiology. vol 55. issue 1. 2019-11-20. PMID:29429142. |
erratum to: forskolin induces hyperphosphorylation of tau accompanied by cell cycle reactivation in primary hippocampal neurons. |
2019-11-20 |
2023-08-13 |
Not clear |
| Stanislav Sutovsky, Tomas Smolek, Peter Turcani, Robert Petrovic, Petra Brandoburova, Santosh Jadhav, Petr Novak, Johannes Attems, Norbert Zilk. Neuropathology and biochemistry of early onset familial Alzheimer's disease caused by presenilin-1 missense mutation Thr116Asn. Journal of neural transmission (Vienna, Austria : 1996). vol 125. issue 6. 2019-11-12. PMID:29404783. |
in the neocortex, tau pathology, especially neuropil threads, was more abundant in the frontal and occipital cortex and in the hippocampus. |
2019-11-12 |
2023-08-13 |
human |
| Minh Bao Huynh, Mohand Ouidir Ouidja, Sandrine Chantepie, Gilles Carpentier, Auriane Ma\\xc3\\xafza, Ganlin Zhang, Joao Vilares, Rita Raisman-Vozari, Dulce Papy-Garci. Glycosaminoglycans from Alzheimer's disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau. PloS one. vol 14. issue 1. 2019-11-04. PMID:30608949. |
glycosaminoglycans from alzheimer's disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau. |
2019-11-04 |
2023-08-13 |
Not clear |
| Minh Bao Huynh, Mohand Ouidir Ouidja, Sandrine Chantepie, Gilles Carpentier, Auriane Ma\\xc3\\xafza, Ganlin Zhang, Joao Vilares, Rita Raisman-Vozari, Dulce Papy-Garci. Glycosaminoglycans from Alzheimer's disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau. PloS one. vol 14. issue 1. 2019-11-04. PMID:30608949. |
here, we show that total sulfated gags from hippocampus of alzheimer's disease have altered capacities to bind and potentiate the activities of growth factors including fgf-2, vegf, and bdnf while their capacity to bind to tau is remarkable increased. |
2019-11-04 |
2023-08-13 |
Not clear |
| Donghong Su, Wenlong Li, Xiaojun She, Xuewei Chen, Qingfeng Zhai, Bo Cui, Rui Wan. Chronic noise exposure exacerbates AD-like neuropathology in SAMP8 mice in relation to Wnt signaling in the PFC and hippocampus. Scientific reports. vol 8. issue 1. 2019-10-31. PMID:30279527. |
chronic noise exposure led to progressive overproduction of a\xce\xb2 and increased the hyperphosphorylation of tau at ser396, thr205, and thr231 sites in the hippocampus and the prefrontal cortex (pfc) in young samp8 mice, similar to that observed in aging samp8 mice. |
2019-10-31 |
2023-08-13 |
mouse |
| Donghong Su, Wenlong Li, Xiaojun She, Xuewei Chen, Qingfeng Zhai, Bo Cui, Rui Wan. Chronic noise exposure exacerbates AD-like neuropathology in SAMP8 mice in relation to Wnt signaling in the PFC and hippocampus. Scientific reports. vol 8. issue 1. 2019-10-31. PMID:30279527. |
these findings demonstrate that chronic noise stress exacerbated ad-like neuropathology, possibly by disrupting wnt signaling and triggering aberrant tau hyperphosphorylation and a\xce\xb2 in the pfc and hippocampus. |
2019-10-31 |
2023-08-13 |
mouse |
| Jeremy Koppel, Heidy Jimenez, Leslie Adrien, Eric H Chang, Anil K Malhotra, Peter Davie. Increased tau phosphorylation follows impeded dopamine clearance in a P301L and novel P301L/COMT-deleted (DM) tau mouse model. Journal of neurochemistry. vol 148. issue 1. 2019-10-28. PMID:30238463. |
in another experiment, acutely following reboxetine injections, tau phosphorylation was quantified in the frontal cortex, striatum, and hippocampus of the mice. |
2019-10-28 |
2023-08-13 |
mouse |
| H-B Zheng, Y-T Fu, G Wang, L-H Sun, Y-Y Fan, T-W Yan. Hyperphosphorylation of protein Tau in hippocampus may cause cognitive dysfunction of propofol-anesthetized rats. European review for medical and pharmacological sciences. vol 22. issue 11. 2019-10-22. PMID:29917212. |
hyperphosphorylation of protein tau in hippocampus may cause cognitive dysfunction of propofol-anesthetized rats. |
2019-10-22 |
2023-08-13 |
rat |
| Willem Huijbers, Aaron P Schultz, Kathryn V Papp, Molly R LaPoint, Bernard Hanseeuw, Jasmeer P Chhatwal, Trey Hedden, Keith A Johnson, Reisa A Sperlin. Tau Accumulation in Clinically Normal Older Adults Is Associated with Hippocampal Hyperactivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 3. 2019-10-16. PMID:30482786. |
tau accumulation in clinically normal older adults is associated with hippocampal hyperactivity. |
2019-10-16 |
2023-08-13 |
human |
| Willem Huijbers, Aaron P Schultz, Kathryn V Papp, Molly R LaPoint, Bernard Hanseeuw, Jasmeer P Chhatwal, Trey Hedden, Keith A Johnson, Reisa A Sperlin. Tau Accumulation in Clinically Normal Older Adults Is Associated with Hippocampal Hyperactivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 3. 2019-10-16. PMID:30482786. |
the relationship between hippocampal hyperactivity and early ad molecular pathology (amyloid-\xce\xb2 and tau accumulation) before clinical symptoms remains to be elucidated. |
2019-10-16 |
2023-08-13 |
human |
| Willem Huijbers, Aaron P Schultz, Kathryn V Papp, Molly R LaPoint, Bernard Hanseeuw, Jasmeer P Chhatwal, Trey Hedden, Keith A Johnson, Reisa A Sperlin. Tau Accumulation in Clinically Normal Older Adults Is Associated with Hippocampal Hyperactivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 3. 2019-10-16. PMID:30482786. |
in this subset, we found that inferior temporal tau accumulation was associated with increased fmri activity in the hippocampus, but showed no clear association with amyloid. |
2019-10-16 |
2023-08-13 |
human |
| Willem Huijbers, Aaron P Schultz, Kathryn V Papp, Molly R LaPoint, Bernard Hanseeuw, Jasmeer P Chhatwal, Trey Hedden, Keith A Johnson, Reisa A Sperlin. Tau Accumulation in Clinically Normal Older Adults Is Associated with Hippocampal Hyperactivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 3. 2019-10-16. PMID:30482786. |
together, the findings support a hypothetical model of the evolution of preclinical ad that place hippocampal hyperactivity concurrent with spread of tau pathology to neocortical regions before clinical impairment. |
2019-10-16 |
2023-08-13 |
human |
| Ramon Velazquez, Eric Ferreira, An Tran, Emily C Turner, Ramona Belfiore, Caterina Branca, Salvatore Odd. Acute tau knockdown in the hippocampus of adult mice causes learning and memory deficits. Aging cell. vol 17. issue 4. 2019-10-14. PMID:29749079. |
acute tau knockdown in the hippocampus of adult mice causes learning and memory deficits. |
2019-10-14 |
2023-08-13 |
mouse |
| Ramon Velazquez, Eric Ferreira, An Tran, Emily C Turner, Ramona Belfiore, Caterina Branca, Salvatore Odd. Acute tau knockdown in the hippocampus of adult mice causes learning and memory deficits. Aging cell. vol 17. issue 4. 2019-10-14. PMID:29749079. |
we found that acute knockdown of tau in the adult hippocampus significantly impaired motor coordination and spatial memory. |
2019-10-14 |
2023-08-13 |
mouse |
| Liang Cai, Kai Lu, Xin Chen, Jing-Yuan Huang, Bao-Ping Zhang, Han Zhan. Auricular vagus nerve stimulation protects against postoperative cognitive dysfunction by attenuating neuroinflammation and neurodegeneration in aged rats. Neuroscience letters. vol 703. 2019-10-11. PMID:30904576. |
concomitant with these beneficial effects, we found that treatment with avns attenuated postoperative neuroinflammation (i.e., the protein level of interleukin-1\xce\xb2 and tumor necrosis factor-\xce\xb1, along with the nuclear protein expression of nf-\xce\xbab) and alzheimer's-related pathology (tau phosphorylation at at-8 and ser396, as well as the levels of a\xce\xb240 and a\xce\xb242) in the hippocampus of the aged rats. |
2019-10-11 |
2023-08-13 |
rat |
| Salil Sharma, Ines Khadimallah, Adam Williamson Corya, Yousuf Omar Ali, Xi Rao, Yunlong Liu, Hui-Chen L. Presymptomatic change in microRNAs modulates Tau pathology. Scientific reports. vol 8. issue 1. 2019-10-09. PMID:29915328. |
to explore whether mir alterations in tauopathy contribute to pathological conditions, we first determined which hippocampal mirs are altered at the presymptomatic and symptomatic stages of tauopathy using rtg4510 mice (tau mice), a well-characterized tauopathy model. |
2019-10-09 |
2023-08-13 |
mouse |
| Tomas Ondrejcak, Igor Klyubin, Grant T Corbett, Graham Fraser, Wei Hong, Alexandra J Mably, Matthew Gardener, Jayne Hammersley, Michael S Perkinton, Andrew Billinton, Dominic M Walsh, Michael J Rowa. Cellular Prion Protein Mediates the Disruption of Hippocampal Synaptic Plasticity by Soluble Tau The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 50. 2019-10-09. PMID:30355631. |
cellular prion protein mediates the disruption of hippocampal synaptic plasticity by soluble tau intracellular neurofibrillary tangles (nfts) composed of tau protein are a neuropathological hallmark of several neurodegenerative diseases, the most common of which is alzheimer's disease (ad). |
2019-10-09 |
2023-08-13 |
rat |
| Tomas Ondrejcak, Igor Klyubin, Grant T Corbett, Graham Fraser, Wei Hong, Alexandra J Mably, Matthew Gardener, Jayne Hammersley, Michael S Perkinton, Andrew Billinton, Dominic M Walsh, Michael J Rowa. Cellular Prion Protein Mediates the Disruption of Hippocampal Synaptic Plasticity by Soluble Tau The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 50. 2019-10-09. PMID:30355631. |
here we investigated the effect of different tau species on synaptic plasticity in the male rat hippocampus |
2019-10-09 |
2023-08-13 |
rat |
| Lindsay A Welikovitch, Sonia Do Carmo, Zs\\xc3\\xb3fia Magl\\xc3\\xb3czky, P\\xc3\\xa9ter Szocsics, J\\xc3\\xa1nos L\\xc5\\x91ke, Tam\\xc3\\xa1s Freund, A Claudio Cuell. Evidence of intraneuronal A\\xce\\xb2 accumulation preceding tau pathology in the entorhinal cortex. Acta neuropathologica. vol 136. issue 6. 2019-10-09. PMID:30362029. |
using well-characterized monoclonal antibodies, we demonstrate that the age-dependent intraneuronal accumulation of soluble a\xce\xb2 is pervasive throughout the entorhinal cortex and hippocampus, and that this phase of the amyloid pathology becomes established within ad-vulnerable regions before the deposition of a\xce\xb2 plaques and the formation of tau neurofibrillary tangles. |
2019-10-09 |
2023-08-13 |
human |
| Kurt A Jellinge. Different patterns of hippocampal tau pathology in Alzheimer's disease and PART. Acta neuropathologica. vol 136. issue 5. 2019-10-08. PMID:30088091. |
different patterns of hippocampal tau pathology in alzheimer's disease and part. |
2019-10-08 |
2023-08-13 |
Not clear |