All Relations between microtubule-associated protein tau and hippocampus

Publication Sentence Publish Date Extraction Date Species
Angie C A Chiang, Xiaojiao Huo, Annemieke Kavelaars, Cobi J Heijne. Chemotherapy accelerates age-related development of tauopathy and results in loss of synaptic integrity and cognitive impairment. Brain, behavior, and immunity. vol 79. 2020-05-13. PMID:30953771. in contrast, we detected only few small tau clusters in the hippocampus of age-matched 11-12 month-old control mice. 2020-05-13 2023-08-13 mouse
Ryan A Kirk, Raymond P Kesner, Li-Ming Wang, Qi Wu, Rheal A Towner, John M Hoffman, Kathryn A Morto. Lipopolysaccharide exposure in a rat sepsis model results in hippocampal amyloid-β plaque and phosphorylated tau deposition and corresponding behavioral deficits. GeroScience. vol 41. issue 4. 2020-05-12. PMID:31473912. lipopolysaccharide exposure in a rat sepsis model results in hippocampal amyloid-β plaque and phosphorylated tau deposition and corresponding behavioral deficits. 2020-05-12 2023-08-13 rat
Ryan A Kirk, Raymond P Kesner, Li-Ming Wang, Qi Wu, Rheal A Towner, John M Hoffman, Kathryn A Morto. Lipopolysaccharide exposure in a rat sepsis model results in hippocampal amyloid-β plaque and phosphorylated tau deposition and corresponding behavioral deficits. GeroScience. vol 41. issue 4. 2020-05-12. PMID:31473912. the focus of this study was to determine whether aβ plaques and phosphorylated tau aggregates occur in the hippocampus as a consequence of lipopolysaccharide administration, and whether behavioral abnormalities related to the hippocampus, particularly the dentate gyrus, can be demonstrated. 2020-05-12 2023-08-13 rat
Ryan A Kirk, Raymond P Kesner, Li-Ming Wang, Qi Wu, Rheal A Towner, John M Hoffman, Kathryn A Morto. Lipopolysaccharide exposure in a rat sepsis model results in hippocampal amyloid-β plaque and phosphorylated tau deposition and corresponding behavioral deficits. GeroScience. vol 41. issue 4. 2020-05-12. PMID:31473912. seven days post injection, aβ plaques and phosphorylated tau in the hippocampus were quantified following immunostaining. 2020-05-12 2023-08-13 rat
Ryan A Kirk, Raymond P Kesner, Li-Ming Wang, Qi Wu, Rheal A Towner, John M Hoffman, Kathryn A Morto. Lipopolysaccharide exposure in a rat sepsis model results in hippocampal amyloid-β plaque and phosphorylated tau deposition and corresponding behavioral deficits. GeroScience. vol 41. issue 4. 2020-05-12. PMID:31473912. lipopolysaccharide treatment results in the deposition of beta amyloid plaques and intracellular phosphorylated tau in the hippocampus, including the dorsal dentate gyrus. 2020-05-12 2023-08-13 rat
Ryan A Kirk, Raymond P Kesner, Li-Ming Wang, Qi Wu, Rheal A Towner, John M Hoffman, Kathryn A Morto. Lipopolysaccharide exposure in a rat sepsis model results in hippocampal amyloid-β plaque and phosphorylated tau deposition and corresponding behavioral deficits. GeroScience. vol 41. issue 4. 2020-05-12. PMID:31473912. lipopolysaccharide administration results in hippocampal deposition of amyloid-beta plaques and intracellular phosphorylated tau and results in specific behavioral deficits attributable to the dorsal dentate gyrus. 2020-05-12 2023-08-13 rat
Jianghao Zhao, Xiaohui Li, Xiongjin Chen, Yujie Cai, Yan Wang, Wenjing Sun, Hui Mai, Jingqi Yang, Weihao Fan, Pei Tang, Mingqian Ou, Yuan Zhang, Xuemei Huang, Bin Zhao, Lili Cu. GRK5 influences the phosphorylation of tau via GSK3β and contributes to Alzheimer's disease. Journal of cellular physiology. vol 234. issue 7. 2020-05-04. PMID:30511419. the activity of both tau and gsk3β in the hippocampus was increased in aged grk5-knockout mice, which is consistent with what occurs in app/ps1 transgenic mice. 2020-05-04 2023-08-13 mouse
Minori Iwata, Shoji Watanabe, Ayaka Yamane, Tomohiro Miyasaka, Hiroaki Misono. Regulatory mechanisms for the axonal localization of tau protein in neurons. Molecular biology of the cell. vol 30. issue 19. 2020-05-01. PMID:31364926. in this study, we found that the axonal localization of tau in cultured rat hippocampal neurons mainly occur during early neuronal development. 2020-05-01 2023-08-13 human
Susanne Wegmann, Rachel E Bennett, Louis Delorme, Ashley B Robbins, Miwei Hu, Danny McKenzie, Molly J Kirk, Julia Schiantarelli, Nahel Tunio, Ana C Amaral, Zhanyun Fan, Samantha Nicholls, Eloise Hudry, Bradley T Hyma. Experimental evidence for the age dependence of tau protein spread in the brain. Science advances. vol 5. issue 6. 2020-04-30. PMID:31249873. old animals showed more tau spreading in the hippocampus and adjacent cortical areas and accumulated more misfolded tau in ec neurons. 2020-04-30 2023-08-13 mouse
Alan King Lun Liu, Tsz Wing Chau, Ernest Junwei Lim, Idil Ahmed, Raymond Chuen-Chung Chang, Michail E Kalaitzakis, Manuel B Graeber, Steve M Gentleman, Ronald K B Pearc. Hippocampal CA2 Lewy pathology is associated with cholinergic degeneration in Parkinson's disease with cognitive decline. Acta neuropathologica communications. vol 7. issue 1. 2020-04-21. PMID:31023342. hippocampal sections from 67 pd, 34 pd with mild cognitive impairment and 96 pdd cases were immunostained for tau and alpha-synuclein, and the respective pathology burden was assessed semi-quantitatively. 2020-04-21 2023-08-13 Not clear
Zhiva Skachokova, Alfonso Martinisi, Martin Flach, Frederik Sprenger, Yvonne Naegelin, Viviane Steiner-Monard, Marc Sollberger, Andreas U Monsch, Michel Goedert, Markus Tolnay, David T Winkle. Cerebrospinal fluid from Alzheimer's disease patients promotes tau aggregation in transgenic mice. Acta neuropathologica communications. vol 7. issue 1. 2020-04-21. PMID:31064413. csf obtained from ad or mci patients increased hippocampal tau hyperphosphorylation and tau tangle formation in these mice at 4 months post-seeding. 2020-04-21 2023-08-13 mouse
Zhiva Skachokova, Alfonso Martinisi, Martin Flach, Frederik Sprenger, Yvonne Naegelin, Viviane Steiner-Monard, Marc Sollberger, Andreas U Monsch, Michel Goedert, Markus Tolnay, David T Winkle. Cerebrospinal fluid from Alzheimer's disease patients promotes tau aggregation in transgenic mice. Acta neuropathologica communications. vol 7. issue 1. 2020-04-21. PMID:31064413. tau pathology was also accentuated in the contralateral hippocampus, and in anterior and posterior directions, indicative of spreading.we provide first evidence for in vivo prion-like properties of ad patients' csf, accelerating tau pathology in susceptible tau transgenic mice. 2020-04-21 2023-08-13 mouse
Yun Zhang, Jing Yang, Wei Jiang, Rong Li, Min Zhu, Feng Xiong, Cui Son. Brain Development Measured With MRI in Children With Down Syndrome Correlates With Blood Biochemical Biomarkers. Pediatric neurology. vol 92. 2020-04-20. PMID:30612744. in a case-control study, we quantitatively evaluated whole brain and hippocampal volumes of ds children and analyzed the correlation of hippocampal volumes with blood levels of aβ, tau and va. 2020-04-20 2023-08-13 Not clear
Jie Zheng, Hong-Lian Li, Na Tian, Fei Liu, Lu Wang, Yaling Yin, Lupeng Yue, Longyu Ma, You Wan, Jian-Zhi Wan. Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission. Cell stem cell. vol 26. issue 3. 2020-04-20. PMID:32142666. interneuron accumulation of phosphorylated tau impairs adult hippocampal neurogenesis by suppressing gabaergic transmission. 2020-04-20 2023-08-13 Not clear
Paula Moyano, Javier Sanjuan, José Manuel García, María José Anadon, Margarita Lobo, Adela Pelayo, Jimena García, María Teresa Frejo, Javier Del Pin. Primary hippocampal estrogenic dysfunction induces synaptic proteins alteration and neuronal cell death after single and repeated paraquat exposure. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 136. 2020-04-13. PMID:31715309. we researched whether pq induces synaptic protein disruption, tau and amyloid beta protein formation, oxidative stress generation, and hippocampal neuronal cell loss through anti-estrogen action in primary hippocampal neurons, after day and two weeks pq treatment, as a probable mechanism of such learning and memory impairment. 2020-04-13 2023-08-13 Not clear
Ryszard Pluta, Anna Bogucka-Kocka, Marzena Ułamek-Kozioł, Jacek Bogucki, Sławomir Januszewski, Janusz Kocki, Stanisław J Czuczwa. Ischemic tau protein gene induction as an additional key factor driving development of Alzheimer's phenotype changes in CA1 area of hippocampus in an ischemic model of Alzheimer's disease. Pharmacological reports : PR. vol 70. issue 5. 2020-04-10. PMID:32002968. ischemic tau protein gene induction as an additional key factor driving development of alzheimer's phenotype changes in ca1 area of hippocampus in an ischemic model of alzheimer's disease. 2020-04-10 2023-08-13 Not clear
Carine Bossenmeyer-Pourié, A David Smith, Sylvain Lehmann, Vincent Deramecourt, Bernard Sablonnière, Jean-Michel Camadro, Grégory Pourié, Racha Kerek, Deborah Helle, Remy Umoret, Rosa-Maria Guéant-Rodriguez, Valérie Rigau, Audrey Gabelle, Jeffrey M Sequeira, Edward V Quadros, Jean-Luc Daval, Jean-Louis Guéan. N-homocysteinylation of tau and MAP1 is increased in autopsy specimens of Alzheimer's disease and vascular dementia. The Journal of pathology. vol 248. issue 3. 2020-04-08. PMID:30734924. compared with controls, n-homocysteinylated tau and map1 were increased and accumulated in protein aggregates and tangles in the cortex, hippocampus and cerebellum of patients and animals. 2020-04-08 2023-08-13 mouse
Ercan Babür, Burak Tan, Marwa Yousef, Sümeyra Cinbaş, Cem Süer, Nurcan Dursu. Deficiency but Not Supplementation of Selenium Impairs the Hippocampal Long-Term Potentiation and Hippocampus-Dependent Learning. Biological trace element research. vol 192. issue 2. 2020-04-07. PMID:30796616. phosphorylated and total tau levels were measured in whole hippocampus by western blot. 2020-04-07 2023-08-13 rat
Ramona Belfiore, Alexis Rodin, Eric Ferreira, Ramon Velazquez, Caterina Branca, Antonella Caccamo, Salvatore Odd. Temporal and regional progression of Alzheimer's disease-like pathology in 3xTg-AD mice. Aging cell. vol 18. issue 1. 2020-03-30. PMID:30488653. phosphorylated tau at ser202/thr205 and ser422 was apparent in the hippocampus of 100% of 6-month-old mice, while only 50% of mice showed tau phosphorylation at thr212/ser214 at this age. 2020-03-30 2023-08-13 mouse
Samuel Chiquita, Mário Ribeiro, João Castelhano, Francisco Oliveira, José Sereno, Marta Batista, Antero Abrunhosa, Ana C Rodrigues-Neves, Rafael Carecho, Filipa Baptista, Catarina Gomes, Paula I Moreira, António F Ambrósio, Miguel Castelo-Branc. A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss. Human molecular genetics. vol 28. issue 13. 2020-03-30. PMID:30816415. molecular characterization evaluated hippocampal levels of amyloid β (aβ) and hyperphosphorylated tau. 2020-03-30 2023-08-13 mouse