| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying-Chun Zhang, Xiao-Mei Liao, Jian-Zhi Wan. [Effect of different culture media on viability and tau protein expression in rat hippocampal slices]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 27. issue 4. 2006-04-28. PMID:16178451. |
[effect of different culture media on viability and tau protein expression in rat hippocampal slices]. |
2006-04-28 |
2023-08-12 |
rat |
| Ying-Chun Zhang, Xiao-Mei Liao, Jian-Zhi Wan. [Effect of different culture media on viability and tau protein expression in rat hippocampal slices]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 27. issue 4. 2006-04-28. PMID:16178451. |
to explore the effect of different culture media on viability and expression of tau protein in organotypic hippocampal slice. |
2006-04-28 |
2023-08-12 |
rat |
| Karin Boekhoorn, Dick Terwel, Barbara Biemans, Peter Borghgraef, Olof Wiegert, Ger J A Ramakers, Koos de Vos, Harm Krugers, Takami Tomiyama, Hiroshi Mori, Marian Joels, Fred van Leuven, Paul J Lucasse. Improved long-term potentiation and memory in young tau-P301L transgenic mice before onset of hyperphosphorylation and tauopathy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 13. 2006-04-18. PMID:16571759. |
the data demonstrate that learning and memory processes in the hippocampus of young tau-p301l mice are not impaired and actually improved in the absence of marked phosphorylation of human tau. |
2006-04-18 |
2023-08-12 |
mouse |
| Karin Boekhoorn, Dick Terwel, Barbara Biemans, Peter Borghgraef, Olof Wiegert, Ger J A Ramakers, Koos de Vos, Harm Krugers, Takami Tomiyama, Hiroshi Mori, Marian Joels, Fred van Leuven, Paul J Lucasse. Improved long-term potentiation and memory in young tau-P301L transgenic mice before onset of hyperphosphorylation and tauopathy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 13. 2006-04-18. PMID:16571759. |
we conclude that protein tau plays an important beneficial role in normal neuronal processes of hippocampal memory, and conversely, that not tau mutations per se, but the ensuing hyperphosphorylation must be critical for cognitive decline in tauopathies. |
2006-04-18 |
2023-08-12 |
mouse |
| M J de Leon, S DeSanti, R Zinkowski, P D Mehta, D Pratico, S Segal, H Rusinek, J Li, W Tsui, L A Saint Louis, C M Clark, C Tarshish, Y Li, L Lair, E Javier, K Rich, P Lesbre, L Mosconi, B Reisberg, M Sadowski, J F DeBernadis, D J Kerkman, H Hampel, L-O Wahlund, P Davie. Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment. Neurobiology of aging. vol 27. issue 3. 2006-04-13. PMID:16125823. |
the lesions of alzheimer's disease: amyloid beta (abeta) deposits, tau pathology and cellular oxidative damage, affect the hippocampus in the earlier stages causing memory impairment. |
2006-04-13 |
2023-08-12 |
Not clear |
| M J de Leon, S DeSanti, R Zinkowski, P D Mehta, D Pratico, S Segal, H Rusinek, J Li, W Tsui, L A Saint Louis, C M Clark, C Tarshish, Y Li, L Lair, E Javier, K Rich, P Lesbre, L Mosconi, B Reisberg, M Sadowski, J F DeBernadis, D J Kerkman, H Hampel, L-O Wahlund, P Davie. Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment. Neurobiology of aging. vol 27. issue 3. 2006-04-13. PMID:16125823. |
relative to control, mci patients showed decreased memory and hippocampal volumes and elevated csf levels of hyperphosphorylated tau and isoprostane. |
2006-04-13 |
2023-08-12 |
Not clear |
| M J de Leon, S DeSanti, R Zinkowski, P D Mehta, D Pratico, S Segal, H Rusinek, J Li, W Tsui, L A Saint Louis, C M Clark, C Tarshish, Y Li, L Lair, E Javier, K Rich, P Lesbre, L Mosconi, B Reisberg, M Sadowski, J F DeBernadis, D J Kerkman, H Hampel, L-O Wahlund, P Davie. Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment. Neurobiology of aging. vol 27. issue 3. 2006-04-13. PMID:16125823. |
among mci patients, over 2 years, longitudinal hippocampal volume losses were closely associated with increasing hyperphosphorylated tau and decreasing amyloid beta-42 levels. |
2006-04-13 |
2023-08-12 |
Not clear |
| Sara Johansson, Ann-Cathrin Radesäter, Richard F Cowburn, Johan Thyberg, Johan Luthma. Modelling of amyloid beta-peptide induced lesions using roller-drum incubation of hippocampal slice cultures from neonatal rats. Experimental brain research. vol 168. issue 1-2. 2006-03-30. PMID:16175362. |
the developed in vitro system may constitute a useful tool for screening novel drugs against abeta-induced alterations of tau and degeneration of hippocampal neurons. |
2006-03-30 |
2023-08-12 |
rat |
| So-Young Park, Adriana Ferreir. The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates beta-amyloid-induced neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 22. 2006-03-02. PMID:15930385. |
recently, we have shown that the microtubule-associated protein tau is essential for beta-amyloid (abeta)-induced neurotoxicity in hippocampal neurons. |
2006-03-02 |
2023-08-12 |
Not clear |
| So-Young Park, Adriana Ferreir. The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates beta-amyloid-induced neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 22. 2006-03-02. PMID:15930385. |
our results showed that pre-aggregated abeta induced the generation of a 17 kda tau fragment in cultured hippocampal neurons. |
2006-03-02 |
2023-08-12 |
Not clear |
| Masashi Kitazawa, Salvatore Oddo, Tritia R Yamasaki, Kim N Green, Frank M LaFerl. Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 39. 2006-02-21. PMID:16192374. |
we further show that administration of roscovitine, a selective and potent inhibitor of cdk5, markedly blocked the lps-induced tau phosphorylation in the hippocampus. |
2006-02-21 |
2023-08-12 |
mouse |
| John G Mielke, Tanya Comas, John Woulfe, Robert Monette, Balu Chakravarthy, Geoffrey A R Mealin. Cytoskeletal, synaptic, and nuclear protein changes associated with rat interface organotypic hippocampal slice culture development. Brain research. Developmental brain research. vol 160. issue 2. 2006-02-07. PMID:16271399. |
between 7 and 28 days following explantation, altered hippocampal morphology could not be detected despite a significant decrease in both map-2c and a mid-range tau isoform by 21 div. |
2006-02-07 |
2023-08-12 |
rat |
| Annica Johansson, Henrik Zetterberg, Harald Hampel, Katharina Buerger, Jonathan A Prince, Lennart Minthon, Lars-Olof Wahlund, Kaj Blenno. Genetic association of CDC2 with cerebrospinal fluid tau in Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 20. issue 6. 2006-01-24. PMID:16192727. |
cdc2 genotypes were evaluated in relation to csf protein levels of total tau, phospho-tau and beta-amyloid(1-42) in ad patients and control individuals, and in relation to the amount of senile plaques and nft in the frontal cortex and in the hippocampus in patients with autopsy-proven ad and controls. |
2006-01-24 |
2023-08-12 |
Not clear |
| David Butler, Queenie B Brown, Douglas J Chin, Lara Batey, Sanjida Karim, Manpreet S Mutneja, David A Karanian, Ben A Bah. Cellular responses to protein accumulation involve autophagy and lysosomal enzyme activation. Rejuvenation research. vol 8. issue 4. 2006-01-24. PMID:16313222. |
these responses were studied in a hippocampal slice model well known for amyloidogenic species, tau aggregates, and ubiquitinated proteins in response to chloroquine-mediated disruption of degradative processes. |
2006-01-24 |
2023-08-12 |
Not clear |
| Isidro Ferrer, Marta Barrachina, Berta Puig, M Martínez de Lagrán, Eulalia Martí, Jesús Avila, Mara Diersse. Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models. Neurobiology of disease. vol 20. issue 2. 2006-01-23. PMID:16242644. |
transgenic mice bearing a triple tau mutation (g272v, p301l, and r406w) and expressing hyper-phosphoyrylated tau in neurons of the entorhinal cortex, hippocampus, and cerebral neocortex show increased expression of dyrk1a in individual neurons in the same regions. |
2006-01-23 |
2023-08-12 |
mouse |
| Songhee Jeon, Yong-Sik Kim, Joobae Park, Chang-Dae Ba. Microtubule affinity-regulating kinase 1 (MARK1) is activated by electroconvulsive shock in the rat hippocampus. Journal of neurochemistry. vol 95. issue 6. 2006-01-20. PMID:16238695. |
mark1 activation and subsequent tau phosphorylation in the hippocampus after ecs was confirmed by an in-gel kinase assay using tau protein as a substrate. |
2006-01-20 |
2023-08-12 |
rat |
| Songhee Jeon, Yong-Sik Kim, Joobae Park, Chang-Dae Ba. Microtubule affinity-regulating kinase 1 (MARK1) is activated by electroconvulsive shock in the rat hippocampus. Journal of neurochemistry. vol 95. issue 6. 2006-01-20. PMID:16238695. |
both mark1 activity and tau phosphorylation were increased in the rat hippocampus after chronic ecs where axonal remodeling was apparent. |
2006-01-20 |
2023-08-12 |
rat |
| W Härtig, M Oklejewicz, A M Strijkstra, A S Boerema, J Stieler, T Arend. Phosphorylation of the tau protein sequence 199-205 in the hippocampal CA3 region of Syrian hamsters in adulthood and during aging. Brain research. vol 1056. issue 1. 2005-11-21. PMID:16095576. |
the present study provides data on the tau phosphorylation status in the hippocampus of euthermic syrian hamsters (mesocricetus auratus), laboratory animals potentially prone to hibernation. |
2005-11-21 |
2023-08-12 |
Not clear |
| Qiong Feng, Bo Cheng, Ru Yang, Feng-Yan Sun, Cui-Qing Zh. Dynamic changes of phosphorylated tau in mouse hippocampus after cold water stress. Neuroscience letters. vol 388. issue 1. 2005-10-28. PMID:16005567. |
dynamic changes of phosphorylated tau in mouse hippocampus after cold water stress. |
2005-10-28 |
2023-08-12 |
mouse |
| Qiong Feng, Bo Cheng, Ru Yang, Feng-Yan Sun, Cui-Qing Zh. Dynamic changes of phosphorylated tau in mouse hippocampus after cold water stress. Neuroscience letters. vol 388. issue 1. 2005-10-28. PMID:16005567. |
to explore the possible long-tem effects of cws on tau phosphorylation, we employed the immunoblot and immunohistochemical methods to analyze the phosphorylation of tau in the hippocampus of mice subjected to cws. |
2005-10-28 |
2023-08-12 |
mouse |