| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tobias Engel, Paloma Goñi-Oliver, José J Lucas, Jesús Avila, Félix Hernánde. Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert. Journal of neurochemistry. vol 99. issue 6. 2007-02-15. PMID:17059563. |
this transgenic line shows tau hyperphosphorylation in hippocampal neurones accompanied by neurofibrillary tangles (nfts). |
2007-02-15 |
2023-08-12 |
mouse |
| Buffie J Clodfelder-Miller, Anna A Zmijewska, Gail V W Johnson, Richard S Jop. Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency. Diabetes. vol 55. issue 12. 2007-01-16. PMID:17130475. |
a massive (fivefold average increase) and widespread at multiple residues (detected with eight different phosphorylation-dependent tau antibodies) increase in the phosphorylation of tau was found in mouse cerebral cortex and hippocampus within 3 days of insulin depletion by streptozotocin treatment. |
2007-01-16 |
2023-08-12 |
mouse |
| Miguel A Riudavets, Ana Rubio, Christopher Cox, Gay Rudow, David Fowler, Juan C Troncos. The prevalence of Alzheimer neuropathologic lesions is similar in blacks and whites. Journal of neuropathology and experimental neurology. vol 65. issue 12. 2007-01-16. PMID:17146288. |
histologic sections of the hippocampus and entorhinal and neocortices were immunostained for abeta and tau proteins. |
2007-01-16 |
2023-08-12 |
human |
| Ying C Yang, Cheng H Lin, Eminy H Y Le. Serum- and glucocorticoid-inducible kinase 1 (SGK1) increases neurite formation through microtubule depolymerization by SGK1 and by SGK1 phosphorylation of tau. Molecular and cellular biology. vol 26. issue 22. 2007-01-09. PMID:16982696. |
in vivo transfection of sgk1 also phosphorylated tau ser214 in hek293t cells and hippocampal neurons. |
2007-01-09 |
2023-08-12 |
Not clear |
| Estefanía T Sáez, Mariana Pehar, Marcelo R Vargas, Luis Barbeito, Ricardo B Maccion. Production of nerve growth factor by beta-amyloid-stimulated astrocytes induces p75NTR-dependent tau hyperphosphorylation in cultured hippocampal neurons. Journal of neuroscience research. vol 84. issue 5. 2006-11-28. PMID:16862561. |
production of nerve growth factor by beta-amyloid-stimulated astrocytes induces p75ntr-dependent tau hyperphosphorylation in cultured hippocampal neurons. |
2006-11-28 |
2023-08-12 |
Not clear |
| Estefanía T Sáez, Mariana Pehar, Marcelo R Vargas, Luis Barbeito, Ricardo B Maccion. Production of nerve growth factor by beta-amyloid-stimulated astrocytes induces p75NTR-dependent tau hyperphosphorylation in cultured hippocampal neurons. Journal of neuroscience research. vol 84. issue 5. 2006-11-28. PMID:16862561. |
abeta-stimulated astrocytes increased tau phosphorylation and reduced the survival of cocultured hippocampal neurons. |
2006-11-28 |
2023-08-12 |
Not clear |
| Estefanía T Sáez, Mariana Pehar, Marcelo R Vargas, Luis Barbeito, Ricardo B Maccion. Production of nerve growth factor by beta-amyloid-stimulated astrocytes induces p75NTR-dependent tau hyperphosphorylation in cultured hippocampal neurons. Journal of neuroscience research. vol 84. issue 5. 2006-11-28. PMID:16862561. |
moreover, exogenous ngf was sufficient to induce tau hyperphosphorylation and death of hippocampal neurons, a phenomenon that was potentiated by a low steady-state concentration of nitric oxide. |
2006-11-28 |
2023-08-12 |
Not clear |
| Carole Abi Farah, Sébastien Perreault, Dalinda Liazoghli, Mylène Desjardins, Angela Anton, Michel Lauzon, Jacques Paiement, Nicole Lecler. Tau interacts with Golgi membranes and mediates their association with microtubules. Cell motility and the cytoskeleton. vol 63. issue 11. 2006-11-28. PMID:16960886. |
overexpression of human tau in primary hippocampal neurons induced the formation of large golgi vesicles that were found in close vicinity to tau-containing microtubules. |
2006-11-28 |
2023-08-12 |
human |
| Ming Li, Guo-dong Gao, Jun Zheng, Li-zhong Sun, Cun Lon. [Effects of taurine on early changes of excitatory amino acids in rabbit brain due to deep hypothermic circulatory arrest]. Zhonghua wai ke za zhi [Chinese journal of surgery]. vol 43. issue 6. 2006-11-20. PMID:15854340. |
to study the effects of taurine (tau) on early changes of excitatory amino acids (eaa) in hippocampus rabbit brain due to deep hypothermic circulatory arrest (dhca). |
2006-11-20 |
2023-08-12 |
rabbit |
| Ian R Mackenzie, Stefanie L Butland, Rebecca S Devon, Emily Dwosh, Howard Feldman, Caroline Lindholm, Scott J Neal, B F Francis Ouellette, Blair R Leavit. Familial frontotemporal dementia with neuronal intranuclear inclusions is not a polyglutamine expansion disease. BMC neurology. vol 6. 2006-11-20. PMID:16945149. |
most of the remaining familial cases do not exhibit tau pathology, but display neuropathology similar to patients with dementia and motor neuron disease, characterized by the presence of ubiquitin-immunoreactive (ub-ir), dystrophic neurites and neuronal cytoplasmic inclusions in the neocortex and hippocampus (ftld-u). |
2006-11-20 |
2023-08-12 |
Not clear |
| Björn Granseth, Benjamin Odermatt, Stephen J Royle, Leon Lagnad. Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses. Neuron. vol 51. issue 6. 2006-11-07. PMID:16982422. |
using an improved fluorescent reporter comprising phluorin fused to synaptophysin, we find that only a slow mode of endocytosis (tau = 15 s) operates at hippocampal synapses when vesicle fusion is triggered by a single nerve impulse or short burst. |
2006-11-07 |
2023-08-12 |
Not clear |
| Eizo Iseki, Ryoko Yamamoto, Norio Murayama, Michiko Minegishi, Takashi Togo, Omi Katsuse, Kenji Kosaka, Haruhiko Akiyama, Kuniaki Tsuchiya, Rohan de Silva, Lees Andrew, Heii Ara. Immunohistochemical investigation of neurofibrillary tangles and their tau isoforms in brains of limbic neurofibrillary tangle dementia. Neuroscience letters. vol 405. issue 1-2. 2006-10-24. PMID:16859829. |
in the present study, we immunohistochemically investigated regional numbers and tau isoforms of nft in the hippocampal area of nine lntd patients with anti-three-repeat (3r) tau-specific and anti-four-repeat (4r) tau-specific antibodies, differentiating nft into three developmental stages of pretangles (pt), nft and ghost tangles (gt). |
2006-10-24 |
2023-08-12 |
Not clear |
| Gloria Patricia Cardona-Gómez, Cesar Arango-Davila, Juan Carlos Gallego-Gómez, Alvaro Barrera-Ocampo, Hernan Pimienta, Luis Miguel Garcia-Segur. Estrogen dissociates Tau and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor subunit in postischemic hippocampus. Neuroreport. vol 17. issue 12. 2006-10-18. PMID:16951581. |
estrogen dissociates tau and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor subunit in postischemic hippocampus. |
2006-10-18 |
2023-08-12 |
Not clear |
| Gloria Patricia Cardona-Gómez, Cesar Arango-Davila, Juan Carlos Gallego-Gómez, Alvaro Barrera-Ocampo, Hernan Pimienta, Luis Miguel Garcia-Segur. Estrogen dissociates Tau and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor subunit in postischemic hippocampus. Neuroreport. vol 17. issue 12. 2006-10-18. PMID:16951581. |
here, we show that transient occlusion of the middle cerebral artery results in the hyperphosphorylation of tau and in a significant increase in the association of tau with glycogen synthase kinase-3beta and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid type glutamate receptor subunits 2/3 in the hippocampus. |
2006-10-18 |
2023-08-12 |
Not clear |
| Gloria Patricia Cardona-Gómez, Cesar Arango-Davila, Juan Carlos Gallego-Gómez, Alvaro Barrera-Ocampo, Hernan Pimienta, Luis Miguel Garcia-Segur. Estrogen dissociates Tau and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor subunit in postischemic hippocampus. Neuroreport. vol 17. issue 12. 2006-10-18. PMID:16951581. |
estradiol treatment decreased hippocampal injury, inhibited glycogen synthase kinase-3beta and decreased the hyperphosphorylation of tau and the interaction of tau with glycogen synthase kinase-3beta and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor. |
2006-10-18 |
2023-08-12 |
Not clear |
| L Pennanen, D P Wolfer, R M Nitsch, J Göt. Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice. Genes, brain, and behavior. vol 5. issue 5. 2006-10-16. PMID:16879631. |
in these mice, tau aggregates are found in many brain areas including the hippocampus and the amygdala, both of which are characterized by nft formation in ad. |
2006-10-16 |
2023-08-12 |
mouse |
| C A Colton, M P Vitek, D A Wink, Q Xu, V Cantillana, M L Previti, W E Van Nostrand, J B Weinberg, B Weinberg, H Dawso. NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 34. 2006-09-29. PMID:16908860. |
genetic removal of no synthase 2 in mice expressing mutated amyloid precursor protein results in pathological hyperphosphorylation of mouse tau, its redistribution to the somatodendritic compartment in cortical and hippocampal neurons, and aggregate formation. |
2006-09-29 |
2023-08-12 |
mouse |
| Othman Ghribi, Brian Larsen, Matthew Schrag, Mary M Herma. High cholesterol content in neurons increases BACE, beta-amyloid, and phosphorylated tau levels in rabbit hippocampus. Experimental neurology. vol 200. issue 2. 2006-09-21. PMID:16696972. |
high cholesterol content in neurons increases bace, beta-amyloid, and phosphorylated tau levels in rabbit hippocampus. |
2006-09-21 |
2023-08-12 |
rabbit |
| Young Hae Chong, Yoo Jeong Shin, Eun Ok Lee, Rakez Kayed, Charles G Glabe, Andrea J Tenne. ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures. The Journal of biological chemistry. vol 281. issue 29. 2006-09-19. PMID:16714296. |
erk1/2 activation mediates abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures. |
2006-09-19 |
2023-08-12 |
rat |
| Young Hae Chong, Yoo Jeong Shin, Eun Ok Lee, Rakez Kayed, Charles G Glabe, Andrea J Tenne. ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures. The Journal of biological chemistry. vol 281. issue 29. 2006-09-19. PMID:16714296. |
therefore, these results suggest that local targeting of the erk1/2 signaling pathway to reduce tau cleavage, as occurs with the inhibition of caspase-3 activation, may modulate the neurotoxic effects of soluble abeta oligomer in the hippocampus and provide the rationale for symptomatic treatment of ad. |
2006-09-19 |
2023-08-12 |
rat |