| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hassan Safari, Neda Khanlarkhani, Aligholi Sobhani, Atefeh Najafi, Fardin Amid. Effect of brain-derived neurotrophic factor (BDNF) on sperm quality of normozoospermic men. Human fertility (Cambridge, England). vol 21. issue 4. 2019-03-07. PMID:28678563. |
the objective of the present study was to evaluate the effect of brain-derived neurotrophic factor (bdnf) on the sperm viability and motility, lipid peroxidation (lpo), mitochondrial activity and concentration of leptin, nitric oxide (no) and insulin in normozoospermic men. |
2019-03-07 |
2023-08-13 |
human |
| Amy K Hauck, Tong Zhou, Wendy Hahn, Raphael Petegrosso, Rui Kuang, Yue Chen, David A Bernloh. Obesity-induced protein carbonylation in murine adipose tissue regulates the DNA-binding domain of nuclear zinc finger proteins. The Journal of biological chemistry. vol 293. issue 35. 2019-03-05. PMID:30012885. |
in obesity-linked insulin resistance, oxidative stress in adipocytes leads to lipid peroxidation and subsequent carbonylation of proteins by diffusible lipid electrophiles. |
2019-03-05 |
2023-08-13 |
Not clear |
| Janin Henkel, Charles Dominic Coleman, Anne Schraplau, Korinna Jӧhrens, Daniela Weber, José Pedro Castro, Martin Hugo, Tim Julius Schulz, Stephanie Krämer, Annette Schürmann, Gerhard Paul Püsche. Induction of steatohepatitis (NASH) with insulin resistance in wildtype B6 mice by a western-type diet containing soybean oil and cholesterol. Molecular medicine (Cambridge, Mass.). vol 23. 2019-01-04. PMID:28332698. |
in the current study, a western-type diet containing soybean oil with high n 6-pufa and 0.75% cholesterol (sod+cho) induced steatosis, inflammation and fibrosis accompanied by hepatic lipid peroxidation and oxidative stress in livers of c57bl/6-mice which in addition showed increased weight gain and insulin resistance, thus displaying a phenotype closely resembling all clinical features of nash in patients with metabolic syndrome. |
2019-01-04 |
2023-08-13 |
mouse |
| A V Dontso. [THE INFLUENCE OF DEFICIT OF ENDOGENOUS NEUROPEPTIDES ON THE CLINICAL COURSE OF CORONARY HEART DISEASE]. Klinicheskaia meditsina. vol 95. issue 2. 2018-12-11. PMID:30303664. |
supplementation of conventional therapy with dalargin results in the increased b-endorphin level, enhanced anti-atherogenic effect, reduced activity of pro-inflammatory cytokines and lipid peroxidation, reduction of leptin, insulin and cortisol levels. |
2018-12-11 |
2023-08-13 |
Not clear |
| Tahereh Setayesh, Armen Nersesyan, Miroslav Mišík, Franziska Ferk, Sabine Langie, Vanessa M Andrade, Alexander Haslberger, Siegfried Knasmülle. Impact of obesity and overweight on DNA stability: Few facts and many hypotheses. Mutation research. Reviews in mutation research. vol 777. 2018-11-21. PMID:30115431. |
ros formation and lipid peroxidation were found in several investigations and may be caused by increased insulin, fatty acid and glucose levels or indirectly via inflammation. |
2018-11-21 |
2023-08-13 |
Not clear |
| E Yu Solov'eva, E D Dzhutova, V S Knyazev. [Pathogenetic approaches to treatment of cognitive disorders in patients with diabetes mellitus]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 116. issue 7. 2018-11-05. PMID:28635936. |
metabolic and vascular mechanisms, oxidative stress, hyperglycemia, glutamate excitotoxicity, insulin insufficiency and brain insulin resistance, general vascular and microcirculatory disturbances, death of cortical neurons, decrease in the newly synthesized acetylcholine, activation of lipid peroxidation are considered. |
2018-11-05 |
2023-08-13 |
Not clear |
| Taiwo Betty Ayeleso, Khosi Ramachela, Emmanuel Mukwevh. Aqueous-Methanol Extracts of Orange-Fleshed Sweet Potato ( Molecules (Basel, Switzerland). vol 23. issue 8. 2018-11-05. PMID:30126082. |
this present study investigated the effects of the extracts of an orange-fleshed sweet potato on oxidative stress biomarkers (glutathione status and lipid peroxidation) and activities of antioxidant enzymes (catalase, cat and glutathione peroxidase, gpx) in palmitate-induced insulin resistant c2c12 cells. |
2018-11-05 |
2023-08-13 |
cat |
| Selcen Cakir, Meryem Eren, Meryem Senturk, Zeynep Soyer Saric. The Effect of Boron on Some Biochemical Parameters in Experimental Diabetic Rats. Biological trace element research. vol 184. issue 1. 2018-10-09. PMID:29019104. |
); blood glucose; plasma insulin; lipase and paraoxonase (pon1) activities; and serum triglyceride, total cholesterol, high-density lipoprotein (hdl) and low-density lipoprotein (ldl) cholesterol, lipid peroxidation (mda), and total antioxidant capacity (tac) in streptozotocin (stz)-induced experimental diabetes in rats. |
2018-10-09 |
2023-08-13 |
rat |
| Yan Gao, Rui Chen, Fengxia Lian. [Mechanisms of acupuncture for non-alcoholic fatty liver disease: researches progress and prospects]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 38. issue 1. 2018-08-15. PMID:29354946. |
after analysis, the possible mechanisms of acupuncture for nafld were summarized from 5 following aspects: acupuncture regulating lipid metabolism and participating lipid metabolism-related signaling pathways, acupuncture improving insulin resistance, acupuncture increasing the antioxidant levels of liver tissue to improve lipid peroxidation, acupuncture inhabiting the expression of inflammatory cytokines, and acupuncture improving the morphology and structure of hepatocyte. |
2018-08-15 |
2023-08-13 |
Not clear |
| Jin-Jun Wang, Hao Jin, Shao-Ling Zheng, Peng Xia, Yong Cai, Xiao-Jie N. Phytoecdysteroids from Ajuga iva act as potential antidiabetic agent against alloxan-induced diabetic male albino rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 96. 2018-07-26. PMID:29031208. |
the present study investigated the protective effect of phytoecdysteroids extracted from the ajuga iva plant on body weight changes, blood glucose, insulin total protein, blood urea nitrogen (bun), creatinine, triglycerides (tg), cholesterol, lipid peroxidation, antioxidant enzymes, pancreatic histopathology and hexokinase-i expression in the alloxan-induced diabetic rats. |
2018-07-26 |
2023-08-13 |
rat |
| Arnold N Onyang. The Contribution of Singlet Oxygen to Insulin Resistance. Oxidative medicine and cellular longevity. vol 2017. 2018-07-02. PMID:29081894. |
recent studies showed that elevated singlet oxygen-mediated lipid peroxidation precedes and predicts diet-induced insulin resistance (ir), and neutrophils were suggested to be responsible for such singlet oxygen production. |
2018-07-02 |
2023-08-13 |
Not clear |
| Patricia Chimin, Maynara L Andrade, Thiago Belchior, Vivian A Paschoal, Juliana Magdalon, Alex S Yamashita, Érique Castro, Angela Castoldi, Adriano B Chaves-Filho, Marcos Y Yoshinaga, Sayuri Miyamoto, Niels O Câmara, William T Festucci. Adipocyte mTORC1 deficiency promotes adipose tissue inflammation and NLRP3 inflammasome activation via oxidative stress and de novo ceramide synthesis. Journal of lipid research. vol 58. issue 9. 2018-04-24. PMID:28679588. |
despite reducing adiposity, adipocyte mtorc1 deficiency promoted hepatic steatosis, insulin resistance, and adipose tissue inflammation (increased infiltration of macrophages, neutrophils, and b lymphocytes; crown-like structure density; tnf-α, interleukin (il)-6, and monocyte chemoattractant protein 1 expression; il-1β protein content; lipid peroxidation; and de novo ceramide synthesis). |
2018-04-24 |
2023-08-13 |
mouse |
| Rahmat Ali Kha. Antidiabetic, Antioxidant, and Hypolipidemic Potential of Sonchus asper Hill. Alternative therapies in health and medicine. vol 23. issue 5. 2018-03-21. PMID:28236622. |
outcome measures • the research team performed (1) a serum analysis for glucose, lipase, and insulin; (2) a measurement of the protein concentration of the supernatant from pancreatic tissue; (3) an assay of catalase activity; (4) an assay of superoxide activity; (5) an assessment of lipid peroxidation enzymes; (6) an assay of glutathione-s-transferase activity; (7) an assay of glutathione reductase activity; (8) an assay of glutathione-peroxidase activity; and (9) an assay of lipid peroxidation (tbars) activity. |
2018-03-21 |
2023-08-13 |
rat |
| Oluwafemi Adeleke Ojo, Basiru Olaitan Ajiboye, Adebola Busola Ojo, Babatunji Emmanuel Oyinloye, Oluwatosin Debbie Imiere, Oluwatosin Adeyon. Ameliorative potential of Blighia sapida K.D. Koenig bark against pancreatic β-cell dysfunction in alloxan-induced diabetic rats. Journal of complementary & integrative medicine. vol 14. issue 3. 2018-02-02. PMID:28306534. |
the significant increase in the lipid peroxidation (malonaldehyde), homeostasis model assessment-insulin resistance scores (homa-ir) and decrease in serum insulin, pancreatic β-cell scores as well as antioxidant marker enzymes in untreated diabetic rats compared to normal control rats were reversed by the b. sapida stem bark ethanol extract and glibenclamide. |
2018-02-02 |
2023-08-13 |
rat |
| Sofiane Zidani, Amar Benakmoum, Ali Ammouche, Yasmine Benali, Anissa Bouhadef, Souheila Abbeddo. Effect of dry tomato peel supplementation on glucose tolerance, insulin resistance, and hepatic markers in mice fed high-saturated-fat/high-cholesterol diets. The Journal of nutritional biochemistry. vol 40. 2017-12-29. PMID:27907824. |
the hsf/hc diet significantly increased body weight gain, adipose tissue weight, fasting plasma glucose, fasting plasma insulin and lipid peroxidation and caused the development of liver steatosis and inflammation. |
2017-12-29 |
2023-08-13 |
mouse |
| Parim Brahmanaidu, V V Sathibabu Uddandrao, Vadivukkarasi Sasikumar, Ramavat Ravindar Naik, Suresh Pothani, Mustapha Sabana Begum, M Prasanna Rajeshkumar, Chandrasekar Varatharaju, Balaji Meriga, P Rameshreddy, A Kalaivani, Ganapathy Saravana. Reversal of endothelial dysfunction in aorta of streptozotocin-nicotinamide-induced type-2 diabetic rats by S-Allylcysteine. Molecular and cellular biochemistry. vol 432. issue 1-2. 2017-12-21. PMID:28258439. |
sac (150 mg/kg b.w) showed its therapeutic effects similar to gliclazide in decreasing glucose, insulin resistance, lipid peroxidation, and increasing body weight; insulin, antioxidant enzymes, and mrna levels of nitric oxide synthase, argininosuccinate synthase, and argininosuccinate lyase genes in stz-na rats. |
2017-12-21 |
2023-08-13 |
rat |
| Surya B Kurup, S Min. Averrhoa bilimbi fruits attenuate hyperglycemia-mediated oxidative stress in streptozotocin-induced diabetic rats. Journal of food and drug analysis. vol 25. issue 2. 2017-12-19. PMID:28911678. |
serum glucose, glycated hemoglobin, plasma insulin, hepatic toxicity markers, antioxidant enzymes, lipid peroxidation products, and liver histopathology were assayed checked after 60 days of extract treatment. |
2017-12-19 |
2023-08-13 |
rat |
| Hong Xu, Yang Zhou, Yongxia Liu, Jian Ping, Qiyang Shou, Fangming Chen, Ru Ru. Metformin improves hepatic IRS2/PI3K/Akt signaling in insulin-resistant rats of NASH and cirrhosis. The Journal of endocrinology. vol 229. issue 2. 2017-06-08. PMID:26941037. |
metformin treatment remarkably improved liver function, alleviated lipid peroxidation and histological damages of the liver, and ameliorated glucose intolerance and insulin resistance. |
2017-06-08 |
2023-08-13 |
rat |
| J Oh, M Harper, F Giallongo, D M Bravo, E H Wall, A N Hristo. Effects of rumen-protected Capsicum oleoresin on immune responses in dairy cows intravenously challenged with lipopolysaccharide. Journal of dairy science. vol 100. issue 3. 2017-05-22. PMID:28109601. |
the objective of this experiment was to investigate the effects of rumen-protected capsicum oleoresin (rpc) on productivity and immune responses including feed intake, milk yield and composition, white and red blood cells, lipid peroxidation, and blood concentration of cortisol, haptoglobin, glucose, and insulin in lactating dairy cows experimentally challenged with lipopolysaccharide (lps). |
2017-05-22 |
2023-08-13 |
Not clear |
| Mohamed Elsayed Kelany, Tahir M Hakami, Adel H Oma. Curcumin improves the metabolic syndrome in high-fructose-diet-fed rats: role of TNF-α, NF-κB, and oxidative stress. Canadian journal of physiology and pharmacology. vol 95. issue 2. 2017-05-03. PMID:27901349. |
we evaluated body mass (bm), systolic blood pressure (sbp), homeostasis model assessment of insulin resistance (homa-ir), and serum levels of glucose, insulin, leptin, total cholesterol (tc), triglycerides (tgs), uric acid, malondialdehyde (mda; lipid peroxidation product), and tumor necrosis factor-α (tnf-α; inflammatory cytokine), and serum catalase (endogenous antioxidant) activity and immunohistochemical expression of nuclear factor κb (nf-κb; inflammation-related transcription factor) in hepatocytes. |
2017-05-03 |
2023-08-13 |
rat |