| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Caleigh M Sawicki, Diane L McKay, Nicola M McKeown, Gerard Dallal, C -Y Oliver Chen, Jeffrey B Blumber. Phytochemical Pharmacokinetics and Bioactivity of Oat and Barley Flour: A Randomized Crossover Trial. Nutrients. vol 8. issue 12. 2017-04-17. PMID:27983687. |
in addition to plasma phytochemical concentrations, glucose and insulin responses, biomarkers of antioxidant activity, lipid peroxidation, inflammation, and vascular remodeling were determined over a 24-h period. |
2017-04-17 |
2023-08-13 |
human |
| Kolanji Vinothiya, Natarajan Ashokkuma. Modulatory effect of vanillic acid on antioxidant status in high fat diet-induced changes in diabetic hypertensive rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 87. 2017-02-22. PMID:28088113. |
the effects of vanillic acid on glucose, plasma insulin, systolic and diastolic blood pressure, thiobarbituric acid reactive substances (tbars), hydroperoxides as a lipid peroxidation marker, and the activities of superoxide dismutase (sod), catalase (cat), glutathione peroxidase (gpx), reduced glutathione (gsh), vitamin c and vitamin e as an antioxidant marker, ast and alt as a liver function marker, urea, uric acid and creatinine as a kidney function marker were investigated. |
2017-02-22 |
2023-08-13 |
rat |
| J S Oliveira, A A N Silva, V A Silv. Phytotherapy in reducing glycemic index and testicular oxidative stress resulting from induced diabetes: a review. Brazilian journal of biology = Revista brasleira de biologia. vol 0. 2017-01-12. PMID:27409225. |
plant extracts were evaluated according to their effects on blood glucose and insulin levels, antioxidant enzymes and oxidant levels, lipid peroxidation, total protein, testosterone levels, gonadosomatic index, diameter of seminiferous tubules, seminiferous epithelium height and integrity, number of germ cells at stage vii and apoptosis in the seminiferous epithelium, sperm production, motility, viability and morphology. |
2017-01-12 |
2023-08-13 |
Not clear |
| Valéria Nunes-Souza, Cheila Juliana César-Gomes, Lucas José Sá Da Fonseca, Glaucevane Da Silva Guedes, Salete Smaniotto, Luíza Antas Rabel. Aging Increases Susceptibility to High Fat Diet-Induced Metabolic Syndrome in C57BL/6 Mice: Improvement in Glycemic and Lipid Profile after Antioxidant Therapy. Oxidative medicine and cellular longevity. vol 2016. 2016-12-16. PMID:27057272. |
nevertheless, the old group presented significant increase in fasting insulin levels, insulin resistance, plasma and hepatic lipid peroxidation, and pronounced steatosis. |
2016-12-16 |
2023-08-13 |
mouse |
| C Zou, Q Qiu, H Chen, L Dou, J Lian. Hepatoprotective effects of selenium during diabetes in rats. Human & experimental toxicology. vol 35. issue 2. 2016-10-14. PMID:25820154. |
the effects of different treatments were studied on various parameters in rat liver, which included serum glucose levels, serum insulin levels, alkaline phosphatase (alp), aspartate aminotransferase (ast), alanine aminotransferase (alt), lipid peroxidation (lpo), glutathione reduced (gsh), oxidized glutathione (gssg), total glutathione (tg), superoxide dismutase (sod), catalase (cat), glutathione reductase, glutathione peroxidase, metallothionein (mt), and histoarchitecture. |
2016-10-14 |
2023-08-13 |
rat |
| Javier Martinez-Useros, Jesus Garcia-Foncilla. Obesity and colorectal cancer: molecular features of adipose tissue. Journal of translational medicine. vol 14. 2016-10-10. PMID:26801617. |
other product of lipid peroxidation is malondialdehyde (mda) being able to regulate insulin through wnt-pathway as well as having demonstrated its mutagenic capability. |
2016-10-10 |
2023-08-13 |
Not clear |
| Matthew J Picklo, John W Newma. Antioxidant supplementation and obesity have independent effects on hepatic oxylipin profiles in insulin-resistant, obesity-prone rats. Free radical biology & medicine. vol 89. 2016-09-22. PMID:26398714. |
recent studies have focused on the extent to which obesity-induced insulin resistance is mediated through oxylipins, derived from enzymatic and nonenzymatic lipid peroxidation. |
2016-09-22 |
2023-08-13 |
rat |
| Georgina Del Vecchyo-Tenorio, Maricela Rodríguez-Cruz, Adolfo Andrade-Cetto, René Cárdenas-Vázque. Creosote Bush (Larrea tridentata) Improves Insulin Sensitivity and Reduces Plasma and Hepatic Lipids in Hamsters Fed a High Fat and Cholesterol Diet. Frontiers in pharmacology. vol 7. 2016-07-22. PMID:27445827. |
the beneficial effects of creosote bush ethanolic extract in the hfd hamster model were a reduction of insulin resistance, associated with lower serum insulin and leptin, lower hepatic lipid peroxidation and higher liver antioxidant capacity. |
2016-07-22 |
2023-08-13 |
Not clear |
| Savannah Tallino, Megan Duffy, Martina Ralle, María Paz Cortés, Mauricio Latorre, Jason L Burkhea. Nutrigenomics analysis reveals that copper deficiency and dietary sucrose up-regulate inflammation, fibrosis and lipogenic pathways in a mature rat model of nonalcoholic fatty liver disease. The Journal of nutritional biochemistry. vol 26. issue 10. 2016-06-16. PMID:26033743. |
low dietary cu decreased hepatic and serum cu (p ≤ 0.05), promoted lipid peroxidation and induced nafld-like histopathology, while the combined factors also induced fasting hepatic insulin resistance and liver damage. |
2016-06-16 |
2023-08-13 |
rat |
| Stéphanie Dal, Nathalie Jeandidier, Elodie Seyfritz, William Bietiger, Claude Péronet, François Moreau, Michel Pinget, Elisa Maillard, Séverine Sigris. Featured Article: Oxidative stress status and liver tissue defenses in diabetic rats during intensive subcutaneous insulin therapy. Experimental biology and medicine (Maywood, N.J.). vol 241. issue 2. 2016-05-18. PMID:26385497. |
body weight, fructosamine level, total cholesterol, insulin growth factor-1 (igf-1) level, lipid peroxidation, and total antioxidant capacity were measured. |
2016-05-18 |
2023-08-13 |
rat |
| Chandrabose Sureka, Thiyagarajan Ramesh, Vavamohaideen Hazeena Begu. Attenuation of erythrocyte membrane oxidative stress by Sesbania grandiflora in streptozotocin-induced diabetic rats. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 93. issue 4. 2016-05-16. PMID:26176361. |
in this study plasma insulin and haemoglobin levels were decreased and blood glucose, glycosylated haemoglobin, protein oxidation, lipid peroxidation markers, and osmotic fragility levels were increased in diabetic rats. |
2016-05-16 |
2023-08-13 |
rat |
| V Ramachandran, R Saravana. Glucose uptake through translocation and activation of GLUT4 in PI3K/Akt signaling pathway by asiatic acid in diabetic rats. Human & experimental toxicology. vol 34. issue 9. 2016-05-16. PMID:26286522. |
oral treatment with aa (20 mg/kg body weight) showed near-normalized levels of plasma glucose, lipid peroxidation products, and antioxidants and improved insulin, ir, irs-1/2, pi3k, akt, and glut4 proteins. |
2016-05-16 |
2023-08-13 |
rat |
| Narendra Kumar, Anand Ka. Pyrroloquinoline quinone (PQQ) has potential to ameliorate streptozotocin-induced diabetes mellitus and oxidative stress in mice: A histopathological and biochemical study. Chemico-biological interactions. vol 240. 2016-03-15. PMID:26343954. |
stz-treated animals developed oxidative stress as indicated by a significant increase in tissue lipid peroxidation (lpo) and lipid hydroperoxide, serum glucose, total cholesterol, triglyceride and urea, with a parallel decrease in the levels of serum insulin and tissue antioxidants. |
2016-03-15 |
2023-08-13 |
mouse |
| Manijheh Sabokdast, Mehran Habibi-Rezaei, Ali Akbar Moosavi-Movahedi, Maryam Ferdousi, Effat Azimzadeh-Irani, Najmeh Poursasa. Protection by beta-Hydroxybutyric acid against insulin glycation, lipid peroxidation and microglial cell apoptosis. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences. vol 23. 2016-03-09. PMID:26311627. |
protection by beta-hydroxybutyric acid against insulin glycation, lipid peroxidation and microglial cell apoptosis. |
2016-03-09 |
2023-08-13 |
Not clear |
| Manijheh Sabokdast, Mehran Habibi-Rezaei, Ali Akbar Moosavi-Movahedi, Maryam Ferdousi, Effat Azimzadeh-Irani, Najmeh Poursasa. Protection by beta-Hydroxybutyric acid against insulin glycation, lipid peroxidation and microglial cell apoptosis. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences. vol 23. 2016-03-09. PMID:26311627. |
here, we report the effect of beta-hydroxy butyrate (bhb) (the predominant ketone body) on the formation of insulin-age, insulin glycation derived liposomal lipid peroxidation and insulin-age toxicity in microglial cells. |
2016-03-09 |
2023-08-13 |
Not clear |
| R Amini, R Yazdanparast, S H Ghaffar. Apigenin modulates the expression levels of pro-inflammatory mediators to reduce the human insulin amyloid-induced oxidant damages in SK-N-MC cells. Human & experimental toxicology. vol 34. issue 6. 2016-03-02. PMID:25304968. |
in addition, apigenin attenuated insulin fibril-induced ros production and lipid peroxidation. |
2016-03-02 |
2023-08-13 |
human |
| María Eugenia D'Alessandro, Dante Selenscig, Paola Illesca, Adriana Chicco, Yolanda B Lombard. Time course of adipose tissue dysfunction associated with antioxidant defense, inflammatory cytokines and oxidative stress in dyslipemic insulin resistant rats. Food & function. vol 6. issue 4. 2016-03-01. PMID:25765549. |
the results suggest that lipid peroxidation, depletion of antioxidant defenses and changes in inflammatory cytokines induced by a sucrose-rich diet contribute to the dysregulation of adipose tissue and insulin resistance. |
2016-03-01 |
2023-08-13 |
rat |
| Nayara Simon Gonzalez Schumacher, Talita Cristina Colomeu, Daniella de Figueiredo, Virginia de Campos Carvalho, Cinthia Baú Betim Cazarin, Marcelo Alexandre Prado, Laura Maria Molina Meletti, Ricardo de Lima Zollne. Identification and Antioxidant Activity of the Extracts of Eugenia uniflora Leaves. Characterization of the Anti-Inflammatory Properties of Aqueous Extract on Diabetes Expression in an Experimental Model of Spontaneous Type 1 Diabetes (NOD Mice). Antioxidants (Basel, Switzerland). vol 4. issue 4. 2016-01-20. PMID:26783951. |
we verified that the chronic consumption of aqueous extract reduces the inflammatory infiltrate index in pancreatic islets, maintaining serum insulin levels and hepatic glutathione, and reducing serum lipid peroxidation as well as the risk for diabetes. |
2016-01-20 |
2023-08-13 |
mouse |
| S A Köse, M Nazıroğl. N-acetyl cysteine reduces oxidative toxicity, apoptosis, and calcium entry through TRPV1 channels in the neutrophils of patients with polycystic ovary syndrome. Free radical research. vol 49. issue 3. 2015-12-16. PMID:25666878. |
serum lipid peroxidation, luteinizing hormone, testosterone, insulin, interleukin-1 beta, and homocysteine levels were decreased by nac treatment although serum vitamin a, beta-carotene, vitamin e, and total antioxidant status were increased by the nac treatment. |
2015-12-16 |
2023-08-13 |
human |
| Mohammad A Rezvanfar, Sepideh Saadat, Habib A Shojaei Saadi, Parisa Mansoori, Sarah Saeedi, Maziar Gooshe, Maryam Baeeri, Mohammad Abdollah. Cellular and molecular mechanisms of pentoxifylline's beneficial effects in experimental polycystic ovary. Theriogenology. vol 83. issue 6. 2015-12-01. PMID:25557188. |
the inflammatory and os responses and their connections with ovarian functionality in induced pco rats were investigated through ovarian histopathologic examination and a series of biochemical measurements including serum estradiol, progesterone, testosterone, insulin, and tnf-α, ovarian and serum lipid peroxidation, total antioxidant power, and reactive oxygen species. |
2015-12-01 |
2023-08-13 |
rat |