| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Benjarat Janson, Janjira Prasomthong, Wachirawadee Malakul, Tantip Boonsong, Sakara Tunsopho. Hibiscus sabdariffa L. calyx extract prevents the adipogenesis of 3T3-L1 adipocytes, and obesity-related insulin resistance in high-fat diet-induced obese rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 138. 2021-07-22. PMID:33721756. |
the results demonstrated that roselle had the potential to reduce body weight, food intake, lipid profiles, inflammatory cytokines, lipid peroxidation, serum leptin, insulin and duodenal glucose absorption, while significantly increased glucose uptake of adipose tissue and muscle when compared to the hfd group. |
2021-07-22 |
2023-08-13 |
rat |
| Liwei Zhang, Wen Chu, Lei Zheng, Juanjuan Li, Yuling Ren, Liping Xue, Wenhua Duan, Qing Wang, Hua L. Zinc oxide nanoparticles from Cyperus rotundus attenuates diabetic retinopathy by inhibiting NLRP3 inflammasome activation in STZ-induced diabetic rats. Journal of biochemical and molecular toxicology. vol 34. issue 12. 2021-07-02. PMID:32692483. |
also, the effect of cr-znonps on drp-induced rats was determined by food intake, fasting blood glucose (fbg), hba1c, insulin, retina thickness, inner nuclear layer (inl), outer nuclear layer (onl) thickness, lipid peroxidation (lpo), catalase (cat), glutathione peroxidase (gpx), and superoxide dismutase (sod). |
2021-07-02 |
2023-08-13 |
rat |
| Liwei Zhang, Wen Chu, Lei Zheng, Juanjuan Li, Yuling Ren, Liping Xue, Wenhua Duan, Qing Wang, Hua L. Zinc oxide nanoparticles from Cyperus rotundus attenuates diabetic retinopathy by inhibiting NLRP3 inflammasome activation in STZ-induced diabetic rats. Journal of biochemical and molecular toxicology. vol 34. issue 12. 2021-07-02. PMID:32692483. |
the administration of streptozotocin (stz)-induced drp rats were increased in the levels of hba1c, fbg, food intake, lpo, and reduced levels of insulin, sod, gpx, and cat. |
2021-07-02 |
2023-08-13 |
rat |
| Glen D Lawrenc. Perspective: The Saturated Fat-Unsaturated Oil Dilemma: Relations of Dietary Fatty Acids and Serum Cholesterol, Atherosclerosis, Inflammation, Cancer, and All-Cause Mortality. Advances in nutrition (Bethesda, Md.). vol 12. issue 3. 2021-06-22. PMID:33693484. |
pufas are susceptible to lipid peroxidation, which can lead to oxidative stress, inflammation, atherosclerosis, cancer, and disorders associated with inflammation, such as insulin resistance, arthritis, and numerous inflammatory syndromes. |
2021-06-22 |
2023-08-13 |
Not clear |
| Kehinde S Olaniyi, Adesola A Oniyide, Oluwaseun A Adeyanju, Lekan S Ojulari, Adams O Omoaghe, Oluranti E Olaiy. Low dose spironolactone-mediated androgen-adiponectin modulation alleviates endocrine-metabolic disturbances in letrozole-induced PCOS. Toxicology and applied pharmacology. vol 411. 2021-05-11. PMID:33359182. |
additionally, elevated fasting blood glucose, 1 h-postload glucose and plasma insulin, impaired glucose tolerance, insulin resistance, reduced insulin sensitivity, increased plasma and ovarian lipid profile, plasma lipid peroxidation, tnf-α, il-6 and decreased plasma glutathione peroxidase and glutathione content were observed. |
2021-05-11 |
2023-08-13 |
rat |
| Dheeraj Kumar Posa, Shahid P Bab. Intracellular pH Regulation of Skeletal Muscle in the Milieu of Insulin Signaling. Nutrients. vol 12. issue 10. 2021-04-12. PMID:32977552. |
numerous reports suggest that pathways such as inflammation, lipid peroxidation products, acidosis and autophagy could cross-talk with insulin-signaling pathway and contribute to diminished insulin responses. |
2021-04-12 |
2023-08-13 |
Not clear |
| Adewumi O Oyabambi, Kehinde S Olaniyi, Ayodele O Soladoye, Lawrence A Olatunj. Suppression of uric acid and lactate production by sodium acetate ameliorates hepatic triglyceride accumulation in fructose-insulin resistant pregnant rats. Environmental toxicology and pharmacology. vol 80. 2021-02-10. PMID:32610186. |
fructose intake resulted in increased body weight gain, liver weight, fluid intake, visceral fat, insulin resistance, fasting blood glucose, insulin, plasma and hepatic tg, total cholesterol, free fatty acid, lipid peroxidation, adenosine deaminase, xanthine oxidase, uric acid, lactate, lactate dehydrogenase, and liver injury marker enzymes. |
2021-02-10 |
2023-08-13 |
rat |
| Muthukumaran Jayachandran, Ramachandran Vinayagam, Baojun X. Guava leaves extract ameliorates STZ induced diabetes mellitus via activation of PI3K/AKT signaling in skeletal muscle of rats. Molecular biology reports. vol 47. issue 4. 2021-02-01. PMID:32240465. |
at the end of the study the lipid peroxidation products, antioxidants, insulin signaling genes were analyzed. |
2021-02-01 |
2023-08-13 |
rat |
| Muthukumaran Jayachandran, Ramachandran Vinayagam, Baojun X. Guava leaves extract ameliorates STZ induced diabetes mellitus via activation of PI3K/AKT signaling in skeletal muscle of rats. Molecular biology reports. vol 47. issue 4. 2021-02-01. PMID:32240465. |
treatment with gle resulted in decreased plasma and skeletal muscle lipid peroxidation markers, increased antioxidants, and improved insulin signaling genes. |
2021-02-01 |
2023-08-13 |
rat |
| Prabhakar Yellanur Konda, Vijayakumar Poondla, Krishna Kumar Jaiswal, Sreenivasulu Dasari, Reddemma Uyyala, Venkata Prasad Surtineni, Janardhan Yadav Egi, Anthony Johnson Antony Masilamani, Lakshmi Bestha, Sreenath Konanki, Muthukumaran Muthulingam, Lakshman Kumar Lingamgunta, Bindu Prasuna Aloor, Sridevi Tirumalaraju, Ankanna Sade, Venkata Ratnam Kamsala, Sreeharsha Nagaraja, Ranjani Ramakrishnan, Vijayakumar Natesa. Pathophysiology of high fat diet induced obesity: impact of probiotic banana juice on obesity associated complications and hepatosteatosis. Scientific reports. vol 10. issue 1. 2021-01-12. PMID:33037249. |
reduction (p < 0.05) in insulin resistance (5.20 ± 0.03), lipid profile (tc 120 ± 0.05; tg 160 ± 0.24; hdl 38 ± 0.03), liver lipid peroxidation (0.7 ± 0.01), hepatic enzyme markers (ast 82 ± 0.06; alt 78 ± 0.34; alp 42 ± 0.22), and hepatic steatosis by increasing liver antioxidant potential (cat 1.4 ± 0.30; gsh 1.04 ± 0.04; sod 0.82 ± 0.22) with normal hepatic triglycerides (15 ± 0.02) and glycogen (0.022 ± 0.15) contents and also showed normal liver size, less accumulation of lipid droplets with only a few congestion. |
2021-01-12 |
2023-08-13 |
rat |
| Sara Nunes, André Alves, Inês Preguiça, Adelaide Barbosa, Pedro Vieira, Fernando Mendes, Diana Martins, Sofia D Viana, Flávio Rei. Crescent-Like Lesions as an Early Signature of Nephropathy in a Rat Model of Prediabetes Induced by a Hypercaloric Diet. Nutrients. vol 12. issue 4. 2020-12-15. PMID:32218109. |
when compared with the control animals, hsuhf-treated rats displayed a metabolic phenotype compatible with obese prediabetes, displaying impaired glucose tolerance and insulin sensitivity, along with hypertriglyceridemia, and lipid peroxidation. |
2020-12-15 |
2023-08-13 |
rat |
| Phiwayinkosi V Dludla, Sonia Silvestri, Patrick Orlando, Kwazi B Gabuza, Sithandiwe E Mazibuko-Mbeje, Tawanda M Nyambuya, Vuyolwethu Mxinwa, Kabelo Mokgalaboni, Rabia Johnson, Christo J F Muller, Luca Tiano, Johan Louw, Bongani B Nkambul. Exploring the Comparative Efficacy of Metformin and Resveratrol in the Management of Diabetes-associated Complications: A Systematic Review of Preclinical Studies. Nutrients. vol 12. issue 3. 2020-12-09. PMID:32168855. |
in particular, both compounds showed strong ameliorative effects against hyperglycemia, dyslipidemia, insulin resistance, a pro-inflammatory response, and lipid peroxidation in various experimental models of diabetes. |
2020-12-09 |
2023-08-13 |
Not clear |
| Tomoki Nishikawa, Naoto Nagata, Tetsuro Shimakami, Takashi Shirakura, Chieko Matsui, Yinhua Ni, Fen Zhuge, Liang Xu, Guanliang Chen, Mayumi Nagashimada, Taro Yamashita, Yoshio Sakai, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Shuichi Kaneko, Tsuguhito Ot. Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice. Scientific reports. vol 10. issue 1. 2020-11-24. PMID:31965018. |
these reductions in hepatic xo activity and ua levels were accompanied by attenuation of insulin resistance, lipid peroxidation, and classically activated m1-like macrophage accumulation in the liver. |
2020-11-24 |
2023-08-13 |
mouse |
| Mona H Hafez, Samar S Elblehi, Yasser S El-Saye. Date palm fruit extract ameliorated pancreatic apoptosis, endocrine dysfunction and regulatory inflammatory cytokines in Streptozotocin-induced diabetes in rats. Environmental science and pollution research international. vol 27. issue 34. 2020-11-04. PMID:32737781. |
diabetic rats exhibited hyperglycemia; increment of pancreatic malondialdehyde (lipid peroxidation biomarker), tumor necrosis factor-α (tnf-α), and interleukin-1β (il-1β); and decrement of plasma insulin and pancreatic antioxidants: glutathione, superoxide dismutase, and catalase values. |
2020-11-04 |
2023-08-13 |
rat |
| Liana L Rodrigues, Jamie A Cooper, Chad M Pato. Acute consumption of Black walnuts increases fullness and decreases lipid peroxidation in humans. Nutrition research (New York, N.Y.). vol 71. 2020-11-03. PMID:31757635. |
we hypothesized that walnut-containing meals would mitigate post-meal increases in glucose, insulin, triglycerides, and lipid peroxidation while increasing tac compared to the traditional meal without nuts. |
2020-11-03 |
2023-08-13 |
human |
| Dragana Rajcic, Annette Brandt, Cheng Jun Jin, Victor Sánchez, Anna Janina Engstler, Finn Jung, Anika Nier, Anja Baumann, Ina Berghei. Exchanging dietary fat source with extra virgin olive oil does not prevent progression of diet-induced non-alcoholic fatty liver disease and insulin resistance. PloS one. vol 15. issue 9. 2020-10-28. PMID:32881925. |
markers of lipid metabolism and lipid peroxidation in liver and of insulin signaling in liver and muscle were also similarly altered in bfc- and ofc-fed mice. |
2020-10-28 |
2023-08-13 |
mouse |
| Edgar Acosta-García, Diamela Carias, María Páez, Gloria Naddaf, Zury Domíngue. [Lipid peroxidation in pubescent adolescents]. Revista de salud publica (Bogota, Colombia). vol 20. issue 5. 2020-10-28. PMID:33111897. |
to assess lipid peroxidation in pubescent adolescents with excess weight and the presence or absence of insulin resistance. |
2020-10-28 |
2023-08-13 |
Not clear |
| Seong-Hee Ko, Hyun-Sook Ki. Menopause-Associated Lipid Metabolic Disorders and Foods Beneficial for Postmenopausal Women. Nutrients. vol 12. issue 1. 2020-10-23. PMID:31941004. |
alterations in lipid metabolism and excessive adipose tissue play a key role in the synthesis of excess fatty acids, adipocytokines, proinflammatory cytokines, and reactive oxygen species, which cause lipid peroxidation and result in the development of insulin resistance, abdominal adiposity, and dyslipidemia. |
2020-10-23 |
2023-08-13 |
Not clear |
| Muthuraman Pandurangan, Doo Hwan Ki. Therapeutic potential of cyanobacteria against streptozotocin-induced diabetic rats. 3 Biotech. vol 6. issue 1. 2020-10-01. PMID:28330164. |
normal and streptozotocin-diabetic rats were orally administered cyanobacteria for 60 consecutive days, and their blood levels of glucose, insulin, c-peptide, lipid peroxidation, body weight and enzyme changes were determined using standard methods. |
2020-10-01 |
2023-08-13 |
rat |
| Suthat Liangpunsakul, Naga Chalasan. Treatment of Nonalcoholic Fatty Liver Disease. Current treatment options in gastroenterology. vol 6. issue 6. 2020-09-30. PMID:14585234. |
the pathogenesis of nafld and nash is not fully known; however, current evidence suggests that insulin resistance and lipid peroxidation play a role in the pathogenesis of this condition. |
2020-09-30 |
2023-08-12 |
human |