Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
D L Buchanan, T Setiawan, D B Lubahn, J A Taylor, T Kurita, G R Cunha, P S Cook. Tissue compartment-specific estrogen receptor-alpha participation in the mouse uterine epithelial secretory response. Endocrinology. vol 140. issue 1. 1999-01-28. PMID:9886861. |
in the present study, we addressed the question of whether production of uterine epithelial secretory proteins and their messenger rnas (mrnas) requires er alpha in stroma, epithelium, or both by analyzing tissue recombinations composed of uterine tissue from adult er alpha knockout (ko) and neonatal balb/c (wt) mice. |
1999-01-28 |
2023-08-12 |
mouse |
D L Buchanan, T Kurita, J A Taylor, D B Lubahn, G R Cunha, P S Cook. Role of stromal and epithelial estrogen receptors in vaginal epithelial proliferation, stratification, and cornification. Endocrinology. vol 139. issue 10. 1998-10-08. PMID:9751518. |
vaginal epithelium (e) and stroma (s) from adult er alpha knockout (ko) and wild-type (wt) neonatal balb/c mice were enzymatically separated and used to produce four types of tissue recombinants in which epithelium, stroma, or both lack functional er alpha. |
1998-10-08 |
2023-08-12 |
mouse |
M Papiernik, M L de Moraes, C Pontoux, F Vasseur, C Péni. Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency. International immunology. vol 10. issue 4. 1998-07-30. PMID:9620592. |
the absence of this population and/or an inability to produce il-10 may be the missing link between il-2r alpha ko, il-2 ko and il-10 ko mice, which all die of inflammatory bowel disease. |
1998-07-30 |
2023-08-12 |
mouse |
K Vermeire, H Heremans, M Vandeputte, S Huang, A Billiau, P Matthy. Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 11. 1997-06-19. PMID:9164974. |
here, we describe experiments showing that ifn-gamma receptor knockout (ifn-gammar alpha ko) mice of the dba/1 strain develop cia more readily than their wild-type counterparts. |
1997-06-19 |
2023-08-12 |
mouse |
K Vermeire, H Heremans, M Vandeputte, S Huang, A Billiau, P Matthy. Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 11. 1997-06-19. PMID:9164974. |
histologic examination of the joints revealed a massive infiltration of the synovium with mononuclear cells and neutrophils, hyperplasia, and severe pannus formation in ifn-gammar alpha ko mice when such inflammatory lesions were not yet detectable in wild-type mice. |
1997-06-19 |
2023-08-12 |
mouse |
K Vermeire, H Heremans, M Vandeputte, S Huang, A Billiau, P Matthy. Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 11. 1997-06-19. PMID:9164974. |
significantly higher il-2 and lower il-4 serum levels were found in anti-cd3-challenged ifn-gammar alpha ko mice than in wild-type counterparts, both at an early and at a later stage of the disease. |
1997-06-19 |
2023-08-12 |
mouse |
R Metzger, G Melmer, S Schondelmaier, B Heckl-Ostreicher, C Nerl, K Pechhold, J T Epplen, D Kabelit. Leukaemic T cells from patients with chronic lymphocytic leukaemia of T-cell origin respond to Staphylococcus aureus enterotoxin superantigens. Scandinavian journal of immunology. vol 37. issue 2. 1993-03-18. PMID:8434235. |
cd4+cd8+ tcr alpha beta (v beta 12.1)-expressing leukaemic t cells from patient ko (white blood cell count 120,000/microliters) were activated by seb but not by the other tested ses. |
1993-03-18 |
2023-08-12 |
Not clear |
M F Powell, L M Sanders, A Rogerson, V S. Parenteral peptide formulations: chemical and physical properties of native luteinizing hormone-releasing hormone (LHRH) and hydrophobic analogues in aqueous solution. Pharmaceutical research. vol 8. issue 10. 1992-04-08. PMID:1839059. |
the degradation of native lhrh in aqueous buffers of ph approximately 1-10 obeyed the rate equation, kobs = kh + alpha h+ + ko + kho-(alpha ho-)x, where x at 60-100 degrees c was approximately 0.64 and temperature independent. |
1992-04-08 |
2023-08-11 |
Not clear |
R W Kuijpers, N M Faber, H T Cuypers, W H Ouwehand, A E von dem Born. NH2-terminal globular domain of human platelet glycoprotein Ib alpha has a methionine 145/threonine145 amino acid polymorphism, which is associated with the HPA-2 (Ko) alloantigens. The Journal of clinical investigation. vol 89. issue 2. 1992-03-18. PMID:1346615. |
nh2-terminal globular domain of human platelet glycoprotein ib alpha has a methionine 145/threonine145 amino acid polymorphism, which is associated with the hpa-2 (ko) alloantigens. |
1992-03-18 |
2023-08-11 |
human |
R W Kuijpers, N M Faber, H T Cuypers, W H Ouwehand, A E von dem Born. NH2-terminal globular domain of human platelet glycoprotein Ib alpha has a methionine 145/threonine145 amino acid polymorphism, which is associated with the HPA-2 (Ko) alloantigens. The Journal of clinical investigation. vol 89. issue 2. 1992-03-18. PMID:1346615. |
previously, we have established that an antigenic polymorphism of platelets, the hpa-2 or ko alloantigen system, is located on the 45-kd amino-terminal globular domain of gpib alpha. |
1992-03-18 |
2023-08-11 |
human |
R W Kuijpers, W H Ouwehand, P M Bleeker, D Christie, A E von dem Born. Localization of the platelet-specific HPA-2 (Ko) alloantigens on the N-terminal globular fragment of platelet glycoprotein Ib alpha. Blood. vol 79. issue 1. 1992-01-31. PMID:1370207. |
localization of the platelet-specific hpa-2 (ko) alloantigens on the n-terminal globular fragment of platelet glycoprotein ib alpha. |
1992-01-31 |
2023-08-11 |
human |
P G Burhol, H L Waldu. Radioimmunoassay of secretin in acidified plasma. Acta hepato-gastroenterologica. vol 25. issue 6. 1979-02-23. PMID:726817. |
the effective equilibrium constant (keff) according to scatchard was 3.4 x 10(11) l/mol, the average equilibrium constant (ko) according to sips 3.5 x 10(11) l/mol, and the index of heterogeneity (alpha) according to sips 1,00. |
1979-02-23 |
2023-08-11 |
human |
P G Burhol, I Lygren, H L Waldu. Radioimmunoassay of vasoactive intestinal polypeptide in plasma. Scandinavian journal of gastroenterology. vol 13. issue 7. 1979-02-12. PMID:725503. |
the antiserum showed an effective equilibrium constant (keff) according to scatchard of 7.4 x 1011 l/mol, an average equilibrium constant (ko) according to sips of 7.3 x 1011 l/mol, an index of heterogeneity (alpha) according to sips of 0.99, and a negligible cross-reactivity with secretin. |
1979-02-12 |
2023-08-11 |
Not clear |
P G Burhol, H L Waldu. Production and evaluation of secretin antibodies. Acta hepato-gastroenterologica. vol 25. issue 2. 1978-07-15. PMID:654847. |
the effective equilibrium constants (keff) according to scatchard varied between 0.8 x 10(11) and 3.4 x 10(11), the average equilibrium constants (ko) according to sips varied between 0.8 x 10(11) and 3.6 x 10(11), and the indices of heterogeneity (alpha) according to sips were 1.00 or close to 1.00. |
1978-07-15 |
2023-08-11 |
Not clear |