| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Yang, K W Olse. Thermal stability of hemoglobin crosslinked in the T-state by bis(3,5-dibromosalicyl) fumarate. Biochemical and biophysical research communications. vol 174. issue 2. 1991-03-08. PMID:1993051. |
both alpha and beta crosslinked methemoglobins have a denaturation temperature in 0.9 m guanidine of 57 degrees c compared to 41 degrees c of hb a. |
1991-03-08 |
2023-08-11 |
Not clear |
| A Villegas Martíne. [Analysis of a program for atypical familial microcytosis. Molecular basis of alpha-thalassemia]. Sangre. vol 35. issue 4. 1991-02-28. PMID:2274839. |
of the 98 patients, 3 had hb h disease, 70 corresponded to heterozygous alpha 0-thalassaemia, 11 to homozygous alpha(+)-thalassaemia, and 14 to heterozygous alpha (+)-thalassaemia. |
1991-02-28 |
2023-08-11 |
Not clear |
| K D Egeberg, B A Springer, S A Martinis, S G Sligar, D Morikis, P M Champio. Alteration of sperm whale myoglobin heme axial ligation by site-directed mutagenesis. Biochemistry. vol 29. issue 42. 1991-02-27. PMID:2176857. |
his(f8)tyr mb is high-spin, five-coordinate in both the oxidized and reduced states, with the ferric heme iron liganded to the proximal tyrosine, resembling hb m iwate [his(alpha f8)tyr] and hb m hyde park [his(beta f8)tyr]. |
1991-02-27 |
2023-08-11 |
Not clear |
| D Plaseska, F Kutlar, J B Wilson, B B Webber, Y T Zeng, T H Huisma. Hb F-Jiangsu, the first gamma chain variant with a valine----methionine substitution: alpha 2A gamma 2 134(H12)Val----Met. Hemoglobin. vol 14. issue 2. 1991-02-26. PMID:1703137. |
hb f-jiangsu, the first gamma chain variant with a valine----methionine substitution: alpha 2a gamma 2 134(h12)val----met. |
1991-02-26 |
2023-08-11 |
Not clear |
| D Plaseska, H J Li, J B Wilson, F Kutlar, A Kutlar, T H Huisman, J Kulp. Hb F-Brooklyn or alpha 2G gamma 2(66)(E10)Lys----Gln. Hemoglobin. vol 14. issue 2. 1991-02-26. PMID:1703138. |
hb f-brooklyn or alpha 2g gamma 2(66)(e10)lys----gln. |
1991-02-26 |
2023-08-11 |
Not clear |
| T Harano, K Harano, K Doi, S Ueda, K Imai, Y Ohba, F Kutlar, T H Huisma. Hb F-Onoda or alpha 2G gamma 2(146)(HC3)His----Tyr, a newly discovered fetal hemoglobin variant in a Japanese newborn. Hemoglobin. vol 14. issue 2. 1991-02-26. PMID:1703139. |
hb f-onoda or alpha 2g gamma 2(146)(hc3)his----tyr, a newly discovered fetal hemoglobin variant in a japanese newborn. |
1991-02-26 |
2023-08-11 |
Not clear |
| P C Giordano, R Fodde, R Amons, J E Ploem, L F Bernin. Hb J-Anatolia [alpha 61(E10)Lys----Thr]: structural characterization and gene localization of a new alpha chain variant. Hemoglobin. vol 14. issue 2. 1991-02-26. PMID:2272835. |
hb j-anatolia [alpha 61(e10)lys----thr]: structural characterization and gene localization of a new alpha chain variant. |
1991-02-26 |
2023-08-11 |
Not clear |
| J Bardakdjian-Michau, F Galactéros, C T Craesc. Functional and NMR studies of Hb Sassari (Asp-126 alpha----His); role of the inter-subunit contacts in the affinity control of human hemoglobin. Biochimica et biophysica acta. vol 1041. issue 3. 1991-02-21. PMID:2268670. |
functional and nmr studies of hb sassari (asp-126 alpha----his); role of the inter-subunit contacts in the affinity control of human hemoglobin. |
1991-02-21 |
2023-08-11 |
human |
| C Poyart, O Schaad, J Kister, F Galacteros, S J Edelstein, Y Blouquit, N Arou. Hemoglobin Saint Mandé [beta 102 (G4) Asn----Tyr]. Functional studies and structural modeling reveal an altered T state. European journal of biochemistry. vol 194. issue 2. 1991-02-20. PMID:2269272. |
in addition, molecular graphics modeling of hb sm in the oxy and deoxy structures indicate the possibility of a new hydrogen bond in the t state between beta(1)102 tyr and alpha(2)42 tyr. |
1991-02-20 |
2023-08-11 |
Not clear |
| I Weiss, F E Cash, M B Coleman, A Pressley, J G Adams, T Sanguansermsri, S A Liebhaber, M H Steinber. Molecular basis for alpha-thalassemia associated with the structural mutant hemoglobin Suan-Dok (alpha 2 109leu----arg) Blood. vol 76. issue 12. 1991-02-14. PMID:2265255. |
molecular basis for alpha-thalassemia associated with the structural mutant hemoglobin suan-dok (alpha 2 109leu----arg) hemoglobin (hb) suan-dok (alpha 109arg) is a rare alpha-globin structural mutation that is linked to an alpha-thalassemia (alpha-thal) determinant. |
1991-02-14 |
2023-08-11 |
mouse |
| H J Li, X N Zhao, F Qin, H W Li, L Li, X J He, X S Chang, Z M Li, K X Liang, F L Xin. Abnormal hemoglobins in the Silk Road region of China. Human genetics. vol 86. issue 2. 1991-02-12. PMID:2265836. |
two variants [hb tashikuergan or alpha 19(ab1)ala----glu; hb tianshui or beta 39(c5) gln----arg] were observed for the first time. |
1991-02-12 |
2023-08-11 |
Not clear |
| Y Yuthavong, A Bunyaratvej, S Kamchonwongpaisa. Increased susceptibility of malaria-infected variant erythrocytes to the mononuclear phagocyte system. Blood cells. vol 16. issue 2-3. 1991-01-31. PMID:2098019. |
the increased susceptibility to phagocytosis of infected erythrocytes was also found for a number of genetic variants involving the alpha-globin chain, namely, alpha-thal 1 trait (--/alpha alpha), alpha-thal 2 trait (-alpha/alpha alpha), hb h (--/-alpha), hb h/hb constant spring (cs) (--/alpha cs alpha), hb cs trait, and homozygous hb cs erythrocytes. |
1991-01-31 |
2023-08-11 |
Not clear |
| J F Codrington, H W Li, F Kutlar, L H Gu, M Ramachandran, T H Huisma. Observations on the levels of Hb A2 in patients with different beta-thalassemia mutations and a delta chain variant. Blood. vol 76. issue 6. 1990-10-23. PMID:1698102. |
hb a2 and its variant b2 (alpha 2 delta 2(16)(a13)gly----arg) were quantitated in the blood of subjects with three different types of beta-thalassemia and with the delta-b2 anomaly in cis or in trans to the beta-thalassemia determinant. |
1990-10-23 |
2023-08-11 |
human |
| J F Codrington, H W Li, F Kutlar, L H Gu, M Ramachandran, T H Huisma. Observations on the levels of Hb A2 in patients with different beta-thalassemia mutations and a delta chain variant. Blood. vol 76. issue 6. 1990-10-23. PMID:1698102. |
one is consistent with a general mechanism concerning the relative excess of alpha chains in beta chain deficiencies which will combine with delta chains to form variable levels of hb a2 dependent on the severity of the beta chain deficiency. |
1990-10-23 |
2023-08-11 |
human |
| J M de Pablos, M A de las Nieves, A Romero, M Jurado, A García, W F Moo Pen. [Hemoglobin Setif (alpha 94 (G1) Asp----Tyr) in a Spanish family]. Sangre. vol 35. issue 3. 1990-10-11. PMID:2396167. |
the structural analysis of the anomalous globin chain showed substitution of residual aspartic acid in position 94 of the alpha chain by tyrosine (hb setif). |
1990-10-11 |
2023-08-11 |
Not clear |
| R E Benesch, S Kwon. The stability of the heme-globin linkage in some normal, mutant, and chemically modified hemoglobins. The Journal of biological chemistry. vol 265. issue 25. 1990-10-09. PMID:1697581. |
taken together with the finding that the rate was 10 times greater for hb rothschild, which is completely dissociated into alpha beta dimers and 10 times smaller for two cross-linked hemoglobins, the subunits of which cannot dissociate, this showed that the rate of dissociation of heme from alpha beta dimers is very much greater than from tetramers. |
1990-10-09 |
2023-08-11 |
human |
| S H Lin, N T Yu, J Tame, D Shih, J P Renaud, J Pagnier, K Naga. Effect of the distal residues on the vibrational modes of the Fe-CO bond in hemoglobin studied by protein engineering. Biochemistry. vol 29. issue 23. 1990-09-27. PMID:2201408. |
the replacement of val-e11 by ala, leu, ile, and met has no effect on the v(c-o), v(fe-co) stretching or delta(fe-c-o) bending frequencies in both the alpha and beta subunits of hb, although some of these mutations affect the co affinity as much as 40-fold. |
1990-09-27 |
2023-08-11 |
human |
| G Martín, A Villegas, F Calero, S del Palacio, J C López, M López, D Espinó. Hb O Padova in a Spanish Family. Acta haematologica. vol 84. issue 1. 1990-09-20. PMID:2117321. |
haematological and biochemical aspects of a new family with heterozygous hb o padova [alpha 30(b11) glu----lys] is described. |
1990-09-20 |
2023-08-11 |
Not clear |
| J Hundrieser, T Sanguansermsri, M Laig, M Pape, W Kühnau, G Flat. Direct demonstration of the HB Suan-Dok mutation in the alpha 2-globin gene by restriction analysis with Sma I. Hemoglobin. vol 14. issue 1. 1990-09-14. PMID:2384313. |
direct demonstration of the hb suan-dok mutation in the alpha 2-globin gene by restriction analysis with sma i. hb suan-dok [alpha 2(109)(g16)leu-greater than arg beta 2] has an alpha-thalassemia-like effect due to low production and instability of the altered alpha-globin chain. |
1990-09-14 |
2023-08-11 |
Not clear |
| G V Sciarratta, G Ivald. Hb Matera [beta 55(D6)Met----Lys]: a new unstable hemoglobin variant in an Italian family. Hemoglobin. vol 14. issue 1. 1990-09-14. PMID:2384314. |
hb matera's instability is due to an interference in the alpha 1-beta 1 contact of the hemoglobin molecule. |
1990-09-14 |
2023-08-11 |
Not clear |