| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Groff, F Galacteros, G Kalmes, Y Blouquit, H Wajcma. Hb Luxembourg [alpha 24(B5) Tyr----His]: a new unstable variant. Hemoglobin. vol 13. issue 5. 1990-02-01. PMID:2599879. |
hb luxembourg [alpha 24(b5) tyr----his]: a new unstable variant. |
1990-02-01 |
2023-08-11 |
Not clear |
| P Groff, F Galacteros, G Kalmes, Y Blouquit, H Wajcma. Hb Luxembourg [alpha 24(B5) Tyr----His]: a new unstable variant. Hemoglobin. vol 13. issue 5. 1990-02-01. PMID:2599879. |
hb luxembourg [alpha 24(b5)tyr----his] was found in association with mild hemolytic anemia and increased indirect bilirubinemia in a family originating from the netherlands. |
1990-02-01 |
2023-08-11 |
Not clear |
| Y Blouquit, J Bardakdjian, D Lena-Russo, N Arous, H Perrimond, A Orsini, J Rosa, F Galactero. Hb Bruxelles: alpha 2A beta (2)41 or 42(C7 or CD1)Phe deleted. Hemoglobin. vol 13. issue 5. 1990-02-01. PMID:2599881. |
hb bruxelles: alpha 2a beta (2)41 or 42(c7 or cd1)phe deleted. |
1990-02-01 |
2023-08-11 |
Not clear |
| A Villegas, G Martín, J B Wilson, B B Webber, H Hu, A Kutlar, F Kutlar, T H Huisma. Hb Extremadura or alpha 2 beta 2133 (H11)Val----Leu, a new mildly unstable hemoglobin in a Spanish female. Hemoglobin. vol 13. issue 5. 1990-02-01. PMID:2599886. |
hb extremadura or alpha 2 beta 2133 (h11)val----leu, a new mildly unstable hemoglobin in a spanish female. |
1990-02-01 |
2023-08-11 |
Not clear |
| L Ulukutlu, H Ozsahin, J B Wilson, B B Webber, H Hu, A Kutlar, F Kutlar, T H Huisma. Hb Brockton [alpha 2 beta 2138(H16)Ala----Pro] observed in a Turkish girl. Hemoglobin. vol 13. issue 5. 1990-02-01. PMID:2599887. |
hb brockton [alpha 2 beta 2138(h16)ala----pro] observed in a turkish girl. |
1990-02-01 |
2023-08-11 |
Not clear |
| K D Vandegriff, F Medina, M A Marini, R M Winslo. Equilibrium oxygen binding to human hemoglobin cross-linked between the alpha chains by bis(3,5-dibromosalicyl) fumarate. The Journal of biological chemistry. vol 264. issue 30. 1989-11-27. PMID:2808353. |
oxygen equilibrium curves of human hemoglobin ao (hbao) and human hemoglobin cross-linked between the alpha chains (alpha alpha hb) by bis(3,5-dibromosalicyl) fumarate were measured as a function of ph and chloride or organic phosphate concentration. |
1989-11-27 |
2023-08-11 |
human |
| K D Vandegriff, F Medina, M A Marini, R M Winslo. Equilibrium oxygen binding to human hemoglobin cross-linked between the alpha chains by bis(3,5-dibromosalicyl) fumarate. The Journal of biological chemistry. vol 264. issue 30. 1989-11-27. PMID:2808353. |
compared to hbao, the oxygen affinity of alpha alpha hb was lower, cooperativity was maintained, although slightly reduced, and all heterotropic effects were diminished. |
1989-11-27 |
2023-08-11 |
human |
| K D Vandegriff, F Medina, M A Marini, R M Winslo. Equilibrium oxygen binding to human hemoglobin cross-linked between the alpha chains by bis(3,5-dibromosalicyl) fumarate. The Journal of biological chemistry. vol 264. issue 30. 1989-11-27. PMID:2808353. |
however, while the oxygen affinity of t-state alpha alpha hb was slightly reduced at physiologic chloride concentration and in the absence of organic phosphates, kt was the same for both hemoglobins in the presence of 2,3-diphosphoglycerate (or high salt) and higher for alpha alpha hb in the presence of inositol hexaphosphate. |
1989-11-27 |
2023-08-11 |
human |
| K D Vandegriff, F Medina, M A Marini, R M Winslo. Equilibrium oxygen binding to human hemoglobin cross-linked between the alpha chains by bis(3,5-dibromosalicyl) fumarate. The Journal of biological chemistry. vol 264. issue 30. 1989-11-27. PMID:2808353. |
the reduced o2 affinity arises from smaller binding constants for both t- and r-state alpha alpha hb rather than through stabilization of the low affinity conformation. |
1989-11-27 |
2023-08-11 |
human |
| K D Vandegriff, F Medina, M A Marini, R M Winslo. Equilibrium oxygen binding to human hemoglobin cross-linked between the alpha chains by bis(3,5-dibromosalicyl) fumarate. The Journal of biological chemistry. vol 264. issue 30. 1989-11-27. PMID:2808353. |
all four adair constants could be determined for alpha alpha hb under most conditions, but a3 could not be resolved for hbao without constraining a4, suggesting that the cross-link stabilizes triply ligated intermediates of hemoglobin. |
1989-11-27 |
2023-08-11 |
human |
| H Moscoso, M Shyamala, C R Kiefer, F A Garve. Monoclonal antibody to the gamma chain of human fetal hemoglobin used to develop an enzyme immunoassay. Clinical chemistry. vol 35. issue 10. 1989-11-17. PMID:2477174. |
the mab reacts with hb f (alpha 2 gamma 2), hb bart's (gamma 4), and hb kenya (gamma-beta hybrid), but does not cross-react with hb a (alpha 2 beta 2) or hb a2 (alpha 2 delta 2). |
1989-11-17 |
2023-08-11 |
human |
| H W Peng, K B Choo, C H Ho, M S Yen, W Y Liung, C K Lin, Z L Yang, H T Ng, K N Ching, S H Ha. Arrangements of alpha-globin gene cluster in Taiwan. Acta haematologica. vol 82. issue 2. 1989-11-14. PMID:2508397. |
in a gene mapping study on 217 newborn babies in taiwan with alpha- and zeta-globin probes, we have observed 4 cases (1.84%) of alpha-thalassemia-2 heterozygotes (zeta zeta-alpha/zeta zeta alpha alpha) without increased levels of hemoglobin (hb) bart's in the cord blood. |
1989-11-14 |
2023-08-11 |
human |
| H W Peng, K B Choo, C H Ho, M S Yen, W Y Liung, C K Lin, Z L Yang, H T Ng, K N Ching, S H Ha. Arrangements of alpha-globin gene cluster in Taiwan. Acta haematologica. vol 82. issue 2. 1989-11-14. PMID:2508397. |
eleven subjects (5.07%) were found to have the south east asian alpha-thalassemia-1 haplotype (zeta zeta--sea/zeta zeta alpha alpha) with increased hb bart's levels ranging from 2.2 to 9%. |
1989-11-14 |
2023-08-11 |
human |
| H W Peng, K B Choo, C H Ho, M S Yen, W Y Liung, C K Lin, Z L Yang, H T Ng, K N Ching, S H Ha. Arrangements of alpha-globin gene cluster in Taiwan. Acta haematologica. vol 82. issue 2. 1989-11-14. PMID:2508397. |
one case, with hb bart's level of 14% in the cord blood, was found to have the genotype of zeta zeta--sea/zeta zeta alpha alpha t (0.46%). |
1989-11-14 |
2023-08-11 |
human |
| J F Codrington, F Kutlar, H F Harris, J B Wilson, T A Stoming, T H Huisma. Hb A2-Wrens or alpha 2 delta 2 98(FG5) Val----Met, an unstable delta chain variant identified by sequence analysis of amplified DNA. Biochimica et biophysica acta. vol 1009. issue 1. 1989-10-30. PMID:2477064. |
hb a2-wrens or alpha 2 delta 2 98(fg5) val----met, an unstable delta chain variant identified by sequence analysis of amplified dna. |
1989-10-30 |
2023-08-11 |
Not clear |
| H Wajcman, J Delaunay, A Francina, J Rosa, F Galactero. Hemoglobin Nouakchott [alpha 114(GH2)Pro----Leu]: a new hemoglobin variant displaying an unusual increase in hydrophobicity. Biochimica et biophysica acta. vol 998. issue 1. 1989-10-28. PMID:2790052. |
the most striking fact in hb nouakchott [alpha 114(gh2)pro----leu] is the highly increased hydrophobicity of the abnormal chain. |
1989-10-28 |
2023-08-11 |
Not clear |
| T Yang, K W Olse. The effect of crosslinking by bis(3,5-dibromosalicyl) fumarate on the autoxidation of hemoglobin. Biochemical and biophysical research communications. vol 163. issue 2. 1989-10-20. PMID:2783118. |
(1979) biochemistry 18, 4265) and deoxy hb a between lys 99 alpha 1 and lys 99 alpha 2 (chatterjee r. y., et al. |
1989-10-20 |
2023-08-11 |
Not clear |
| T Yang, K W Olse. The effect of crosslinking by bis(3,5-dibromosalicyl) fumarate on the autoxidation of hemoglobin. Biochemical and biophysical research communications. vol 163. issue 2. 1989-10-20. PMID:2783118. |
the autoxidation at 37 degrees c of oxy alpha 99 crosslinked hemoglobin was found to be 1.8 times as fast as that of hb a while that of the oxy beta 82 crosslinked hemoglobin was only 1.2 times as fast. |
1989-10-20 |
2023-08-11 |
Not clear |
| T Yang, K W Olse. The effect of crosslinking by bis(3,5-dibromosalicyl) fumarate on the autoxidation of hemoglobin. Biochemical and biophysical research communications. vol 163. issue 2. 1989-10-20. PMID:2783118. |
after 5 hours the formation of methemoglobin in the alpha crosslinked hb a is 21.3% compared to 10.8% in beta crosslinked hb a and 6.4% in hb a. |
1989-10-20 |
2023-08-11 |
Not clear |
| K Ishimori, I Morishima, K Imai, K Fushitani, G Miyazaki, D Shih, J Tame, J Pegnier, K Niga. NMR study of human mutant hemoglobins synthesized in Escherichia coli. Consequences of tyrosine alpha 42 substitutions. The Journal of biological chemistry. vol 264. issue 25. 1989-10-11. PMID:2670922. |
the site-directed mutagenesis of the tyr alpha 42----phe removes the hydrogen bond described above and prevents transition to the t-state so that the mutant hb is rather similar to the "r-state" even when deoxygenated. |
1989-10-11 |
2023-08-11 |
human |