| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y T Zeng, S Z Huang, M J Che. The types and distribution of alpha-thalassemia-2 in China. Hemoglobin. vol 12. issue 5-6. 1989-02-16. PMID:3209388. |
we studied the nondeletional hb h type by dna gene mapping, digestion with msp i, and hybridization with a 32p-alpha probe for the presence of the hb quong sze [alpha 125(h8)leu----pro] mutation. |
1989-02-16 |
2023-08-11 |
Not clear |
| Y E Hsia, J Yuen, J A Hunt, P Rattamanasay, J Hall, N Takaesu, E A Titus, J Fujita, C A For. The different types of alpha-thalassemia: practical and genetic aspects. Hemoglobin. vol 12. issue 5-6. 1989-02-16. PMID:3209390. |
gene frequencies in the unselected lao subjects were approximately 0.2 for hb e, at least 0.1 for (-alpha), usually a rightward (alpha -3.7) type, 0.04 for (-), and 0.01 for a beta-thal. |
1989-02-16 |
2023-08-11 |
human |
| V V Chan, T K Chan, D Tod. Different forms of Hb H disease in the Chinese. Hemoglobin. vol 12. issue 5-6. 1989-02-16. PMID:3209392. |
of 33 alpha-thal-2 defects studied, 26 were the rightward deletion (alpha -3.7 kb, all type i defects) and seven the leftward deletion (alpha -4.2 kb); one of the latter was associated with hb q. |
1989-02-16 |
2023-08-11 |
Not clear |
| V V Chan, T K Chan, D Tod. Different forms of Hb H disease in the Chinese. Hemoglobin. vol 12. issue 5-6. 1989-02-16. PMID:3209392. |
one patient who inherited classical hb h disease and hb new york (ny) [alpha 113(g15)val----glu] had severe anemia, and required frequent blood transfusions due to the deleterious effect of an increased alpha-ny chain turnover. |
1989-02-16 |
2023-08-11 |
Not clear |
| A Horvath, A Butkus, R J MacIsaac, L Pontefract, E M Wintou. Effect of hormone-induced premature parturition on hemoglobin switching in sheep. Pediatric research. vol 24. issue 6. 1989-02-07. PMID:2462709. |
this study examines the effect of premature delivery on the switch from fetal (alpha 2 tau 2) to adult (alpha 2 beta 2) hb, in lambs in which premature parturition was induced by the intrafetal infusion of acth or corticotropin releasing hormone. |
1989-02-07 |
2023-08-11 |
Not clear |
| R Vestri, A Crema, A Testa, O Losti. Kinetics of the Hb A to Hb C switch and erythropoietin plasma levels in sheep. Animal genetics. vol 19. issue 3. 1989-02-02. PMID:3207219. |
the induction of hb a (alpha 2 beta a2) and hb c (alpha 2 beta c2) synthesis in three adult sheep has been sequentially analysed, in relation to the reduction of the haematocrit (ht) and to the changes of erythropoietin (epo) concentration in plasma. |
1989-02-02 |
2023-08-11 |
Not clear |
| M L North, M C Piffaut, I Duwig, A G Locoh-Donou, A M Locoh-Dono. Detection of haemoglobinopathies at birth in Togo. Nouvelle revue francaise d'hematologie. vol 30. issue 4. 1989-01-12. PMID:3194188. |
our work also confirmed the presence of alpha and beta + thalassaemias (acetyl hb f greater than hb a) in togo. |
1989-01-12 |
2023-08-11 |
Not clear |
| F Baklouti, V Baudin-Chich, J Kister, M Marden, G Teyssier, C Poyart, J Delaunay, H Wajcma. Increased oxygen affinity with normal heterotropic effects in hemoglobin Loire [alpha 88(F9)Ala----Ser]. European journal of biochemistry. vol 177. issue 2. 1989-01-03. PMID:3142772. |
the effects of bezafibrate, which binds specifically to the alpha chains, was similar to that observed in hb a. |
1989-01-03 |
2023-08-11 |
Not clear |
| F Baklouti, V Baudin-Chich, J Kister, M Marden, G Teyssier, C Poyart, J Delaunay, H Wajcma. Increased oxygen affinity with normal heterotropic effects in hemoglobin Loire [alpha 88(F9)Ala----Ser]. European journal of biochemistry. vol 177. issue 2. 1989-01-03. PMID:3142772. |
the functional properties of hb loire may be explained by a slight displacement of some key residues of the c-terminal region of the alpha chain destabilizing the t structure. |
1989-01-03 |
2023-08-11 |
Not clear |
| V B Jogessar, K Westermeyer, B B Webber, J B Wilson, H Hu, J M Gonzalez-Redondo, A Kutlar, T H Huisma. Hb natal or alpha 2(minus Tyr-Arg) beta 2: a high oxygen affinity alpha chain variant with a deleted carboxy-terminus resulting from a TAC----TAA (Tyr----terminating codon) mutation in codon alpha 140. Biochimica et biophysica acta. vol 951. issue 1. 1988-12-28. PMID:3191134. |
hb natal or alpha 2(minus tyr-arg) beta 2: a high oxygen affinity alpha chain variant with a deleted carboxy-terminus resulting from a tac----taa (tyr----terminating codon) mutation in codon alpha 140. |
1988-12-28 |
2023-08-11 |
Not clear |
| V B Jogessar, K Westermeyer, B B Webber, J B Wilson, H Hu, J M Gonzalez-Redondo, A Kutlar, T H Huisma. Hb natal or alpha 2(minus Tyr-Arg) beta 2: a high oxygen affinity alpha chain variant with a deleted carboxy-terminus resulting from a TAC----TAA (Tyr----terminating codon) mutation in codon alpha 140. Biochimica et biophysica acta. vol 951. issue 1. 1988-12-28. PMID:3191134. |
the discovery is reported of a fast-moving alpha chain variant (hb natal) which is characterized by a shortened alpha polypeptide chain because of the deletion of the tyr-arg carboxy-terminal residues. |
1988-12-28 |
2023-08-11 |
Not clear |
| V B Jogessar, K Westermeyer, B B Webber, J B Wilson, H Hu, J M Gonzalez-Redondo, A Kutlar, T H Huisma. Hb natal or alpha 2(minus Tyr-Arg) beta 2: a high oxygen affinity alpha chain variant with a deleted carboxy-terminus resulting from a TAC----TAA (Tyr----terminating codon) mutation in codon alpha 140. Biochimica et biophysica acta. vol 951. issue 1. 1988-12-28. PMID:3191134. |
hb natal or alpha 2 (minus tyr-arg) beta 2 has a high affinity for oxygen without a bohr effect and heme-heme interaction. |
1988-12-28 |
2023-08-11 |
Not clear |
| S L Thein, C Hesketh, R B Wallace, D J Weatheral. The molecular basis of thalassaemia major and thalassaemia intermedia in Asian Indians: application to prenatal diagnosis. British journal of haematology. vol 70. issue 2. 1988-12-23. PMID:2903765. |
comparison of the beta-globin gene cluster haplotypes, alpha globin genotypes and beta gene mutations of the thalassaemia major group with the thalassaemia intermedia group suggests that the co-inheritance of a high hb f determinant associated with the - + - + + 5' beta haplotype and the inheritance of a mild beta-thalassaemia mutation are the major ameliorating factors of disease severity in asian indians. |
1988-12-23 |
2023-08-11 |
Not clear |
| J M González Redondo, J M De Pablo. [Association of alpha thalassemia and Hb G Philadelphia in a Spanish family]. Sangre. vol 33. issue 3. 1988-11-22. PMID:3175819. |
[association of alpha thalassemia and hb g philadelphia in a spanish family]. |
1988-11-22 |
2023-08-11 |
Not clear |
| Y Arata, Y Seno, J Otsuk. A study on the quaternary structure change of hemoglobin in the ligation process. Biochimica et biophysica acta. vol 956. issue 3. 1988-11-16. PMID:3167072. |
when either alpha or beta subunit is substituted with the corresponding subunit in carbonmonoxy hb, serious steric hindrances are produced between alpha 1fg4(92)arg and beta 2c3(37)trp or between alpha 1c6(41)thr and beta 2fg4(97)his, all of which belong to the allosteric core affected directly by ligand binding. |
1988-11-16 |
2023-08-11 |
human |
| R Fodde, M Losekoot, M H van den Broek, M Oldenburg, N Rashida, A Schreuder, J T Wijnen, P C Giordano, N V Nayudu, P M Kha. Prevalence and molecular heterogeneity of alfa+ thalassemia in two tribal populations from Andhra Pradesh, India. Human genetics. vol 80. issue 2. 1988-11-08. PMID:3169739. |
we have confirmed the strict relationship between hb s levels and the number of alpha globin genes in double heterozygotes for the s gene and alpha thalassemia. |
1988-11-08 |
2023-08-11 |
Not clear |
| R Fodde, M Losekoot, M H van den Broek, M Oldenburg, N Rashida, A Schreuder, J T Wijnen, P C Giordano, N V Nayudu, P M Kha. Prevalence and molecular heterogeneity of alfa+ thalassemia in two tribal populations from Andhra Pradesh, India. Human genetics. vol 80. issue 2. 1988-11-08. PMID:3169739. |
in this population sample we did not find either heterozygous carriers of alpha 0 thalassemia (deletion of both alpha genes in "cis") or individuals showing hemolytic anemia due to inactivation of three alpha-globin genes (hb h disease). |
1988-11-08 |
2023-08-11 |
Not clear |
| J M de Pablos, J B Cleg. Hb F-Granada or alpha 2G gamma (2)22(B4)Asp----Val: a new human fetal hemoglobin variant. Hemoglobin. vol 12. issue 4. 1988-11-03. PMID:2459082. |
hb f-granada or alpha 2g gamma (2)22(b4)asp----val: a new human fetal hemoglobin variant. |
1988-11-03 |
2023-08-11 |
human |
| A Kutlar, F Kutlar, J B Wilson, B B Webber, H Hu, T H Huisma. Hb F-Austell or alpha 2G gamma (2)40(C6)Arg----Lys. Hemoglobin. vol 12. issue 4. 1988-11-03. PMID:2459083. |
hb f-austell or alpha 2g gamma (2)40(c6)arg----lys. |
1988-11-03 |
2023-08-11 |
Not clear |
| E N Kosasih, S P Cai, Y W Kan, L E Lie-Inj. Hemoglobin constant spring defined by specific oligonucleotide hybridization and hemoglobin D Punjab (beta 121----Gln) in a Batak Indonesian family. American journal of hematology. vol 29. issue 1. 1988-11-03. PMID:3177365. |
a batak indonesian from north sumatra with hemoglobin (hb) d punjab (alpha 2 beta 2 121----gln) and hemoglobin constant spring (hb cosp) is described. |
1988-11-03 |
2023-08-11 |
Not clear |