| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A E Kulozik, B C Kar, G R Serjeant, B E Serjeant, D J Weatheral. The molecular basis of alpha thalassemia in India. Its interaction with the sickle cell gene. Blood. vol 71. issue 2. 1988-03-04. PMID:2827816. |
patients with sickle cell disease and alpha thalassemia had higher hemoglobin (hb) levels, rbc counts, and hb a2 levels, and lower reticulocyte counts, mcv, mch, and hb f levels than those with a normal alpha genotype. |
1988-03-04 |
2023-08-11 |
Not clear |
| S L Thein, R B Wallace, L Pressley, J B Clegg, D J Weatherall, D R Higg. The polyadenylation site mutation in the alpha-globin gene cluster. Blood. vol 71. issue 2. 1988-03-04. PMID:3337900. |
the alpha 2 polyadenylation signal mutation occurs in other middle eastern and the mediterranean populations and is responsible for the clinical phenotype of hb h disease in some saudi arabian individuals with five alpha genes (alpha t saudi alpha/(alpha alpha alpha)t saudi). |
1988-03-04 |
2023-08-11 |
human |
| Y Wada, E Ikkala, K Imai, T Matsuo, H Matsuda, M Lehtinen, A Hayashi, H Lehman. Structure and function of a new hemoglobin variant, Hb meilahti (alpha 2 beta 2 36(C2)Pro----Thr), characterized by mass spectrometry. Acta haematologica. vol 78. issue 2-3. 1988-01-07. PMID:3120455. |
structure and function of a new hemoglobin variant, hb meilahti (alpha 2 beta 2 36(c2)pro----thr), characterized by mass spectrometry. |
1988-01-07 |
2023-08-11 |
Not clear |
| B Masala, L Manca, A Stangoni, G B Cuccuru, J B Wilson, B B Webber, A Kutlar, T H Huisma. Hb Sassari or alpha (2)126(H9)Asp---His beta 2 observed in a family from Northern Sardinia. Hemoglobin. vol 11. issue 4. 1987-12-03. PMID:3667323. |
hb sassari or alpha (2)126(h9)asp---his beta 2 observed in a family from northern sardinia. |
1987-12-03 |
2023-08-11 |
Not clear |
| C Altay, A Kutlar, J B Wilson, B B Webber, T H Huisma. Hb P-Nilotic or alpha 2(beta delta)2 in a Turkish family. Hemoglobin. vol 11. issue 4. 1987-12-03. PMID:3667326. |
hb p-nilotic or alpha 2(beta delta)2 in a turkish family. |
1987-12-03 |
2023-08-11 |
Not clear |
| K Kleman, B Lubin, A Kutlar, J B Wilson, B B Webber, T H Huisma. A second family with Hb Minneapolis-Laos or alpha 2 beta (2)118(GH1)Phe----Tyr. Hemoglobin. vol 11. issue 4. 1987-12-03. PMID:3667327. |
a second family with hb minneapolis-laos or alpha 2 beta (2)118(gh1)phe----tyr. |
1987-12-03 |
2023-08-11 |
Not clear |
| R E Weber, T Kleinschmidt, G Braunitze. Embryonic pig hemoglobins Gower I (zeta 2 epsilon 2), Gower II (alpha 2 epsilon 2), Heide I (zeta 2 theta 2) and Heide II (alpha 2 theta 2): oxygen-binding functions related to structure and embryonic oxygen supply. Respiration physiology. vol 69. issue 3. 1987-11-18. PMID:2443953. |
the common pig lacks a fetal hemoglobin but has four embryonic hemoglobins: gower i (zeta 2 epsilon 2), gower ii (alpha 2 epsilon 2), heide i (zeta 2 theta 2) and heide ii (alpha 2 theta 2) as well as adult hb a (alpha 2 beta 2) and the amino acid sequence for each of the five constituent polypeptide chains has been established. |
1987-11-18 |
2023-08-11 |
Not clear |
| P J Fleming, D R Sumner, K Wyatt, W G Hughes, W D Melrose, D M Jupe, M J Baiki. Hemoglobin Hobart or alpha 20(Bl)His----Arg: a new alpha chain hemoglobin variant. Hemoglobin. vol 11. issue 3. 1987-11-12. PMID:3654264. |
a new alpha chain hemoglobin variant, hb hobart, alpha 20(bl)his----arg, was detected in a 60-year-old female of british nationality. |
1987-11-12 |
2023-08-11 |
Not clear |
| P J Fleming, D R Sumner, K Wyatt, W G Hughes, W D Melrose, D M Jupe, M J Baiki. Hemoglobin Hobart or alpha 20(Bl)His----Arg: a new alpha chain hemoglobin variant. Hemoglobin. vol 11. issue 3. 1987-11-12. PMID:3654264. |
the substitution in hb hobart is at the first residue in the b helix of the alpha chain of hemoglobin. |
1987-11-12 |
2023-08-11 |
Not clear |
| F Kutlar, A Kutlar, Y C Gu, T H Huisma. Adult hemoglobin levels in newborn babies from different countries and in babies with some significant hemoglobinopathies. Acta haematologica. vol 78. issue 1. 1987-11-02. PMID:3116804. |
the presence of an alpha 2-thalassemia homozygosity (-alpha/ -alpha versus alpha alpha/alpha alpha) did not affect the average hb a level. |
1987-11-02 |
2023-08-11 |
Not clear |
| H Fabritius, L Ferney-Saris, I Sanogo, A Sangare, R Cabanne. [A case of association of Hb C Ziguinchor (alpha A2 beta 6-2 (A3) Glu replaced by Val beta 58 (E2) Pro replaced by Arg) with a hereditary persistence of fetal hemoglobin (HPFH). Clinical and biological results]. Medecine tropicale : revue du Corps de sante colonial. vol 47. issue 2. 1987-10-08. PMID:2442578. |
[a case of association of hb c ziguinchor (alpha a2 beta 6-2 (a3) glu replaced by val beta 58 (e2) pro replaced by arg) with a hereditary persistence of fetal hemoglobin (hpfh). |
1987-10-08 |
2023-08-11 |
Not clear |
| K Kleman, B Lubin, J B Wilson, A Kutlar, B B Webber, T H Huisma. Hb F-Oakland or alpha 2G gamma I2(26)(B8)Glu----Lys. Hemoglobin. vol 11. issue 2. 1987-10-02. PMID:2442122. |
hb f-oakland or alpha 2g gamma i2(26)(b8)glu----lys. |
1987-10-02 |
2023-08-11 |
Not clear |
| A Kutlar, F Kutlar, J B Wilson, B B Webber, J M Gonzalez Redondo, T H Huisma. Hb F-Clarke or alpha 2G gamma 2(65)(E9)Lys----Asn. Hemoglobin. vol 11. issue 2. 1987-10-02. PMID:2442123. |
hb f-clarke or alpha 2g gamma 2(65)(e9)lys----asn. |
1987-10-02 |
2023-08-11 |
Not clear |
| K Indrak, B F Wiedermann, F Batek, J B Wilson, B B Webber, A Kutlar, T H Huisma. Hb Olomouc or alpha 2 beta 2(86)(F2)Ala----Asp, a new high oxygen affinity variant. Hemoglobin. vol 11. issue 2. 1987-10-02. PMID:3623975. |
hb olomouc or alpha 2 beta 2(86)(f2)ala----asp, a new high oxygen affinity variant. |
1987-10-02 |
2023-08-11 |
Not clear |
| A R Bird, T E Elliot, J B Wilson, B B Webber, F Kutlar, A Kutlar, T H Huisma. Hb Borås or alpha 2 beta 2(88)(F4)Leu----Arg in a South African female. Hemoglobin. vol 11. issue 2. 1987-10-02. PMID:3623976. |
hb borås or alpha 2 beta 2(88)(f4)leu----arg in a south african female. |
1987-10-02 |
2023-08-11 |
Not clear |
| F Kutlar, Y J Fei, J B Wilson, A Kutlar, T H Huisma. Detection of the embryonic zeta chain in blood from newborn babies by reversed-phase high-performance liquid chromatography. Journal of chromatography. vol 394. issue 2. 1987-09-28. PMID:2442182. |
the quantity of zeta in normal babies is less than 0.7% [% of (alpha + zeta)] and is dependent upon the maturity of the baby as it was only present in babies with low levels of beta chain or hemoglobin (hb) a. |
1987-09-28 |
2023-08-11 |
Not clear |
| A E Felice, K M McKie, M P Cleek, E M Marino, A Kutlar, V C McKi. Effects of alpha-thalassemia-2 on the developmental changes of hematological values in children with sickle cell disease from Georgia. American journal of hematology. vol 25. issue 4. 1987-09-18. PMID:2441597. |
the hematology and pathophysiology of sickle cell disease during the postnatal development of younger hemoglobin (hb) s homozygotes (ss) could be considerably affected by a variability of alpha globin gene numbers. |
1987-09-18 |
2023-08-11 |
Not clear |
| A E Felice, K M McKie, M P Cleek, E M Marino, A Kutlar, V C McKi. Effects of alpha-thalassemia-2 on the developmental changes of hematological values in children with sickle cell disease from Georgia. American journal of hematology. vol 25. issue 4. 1987-09-18. PMID:2441597. |
around the age of 7, the ss patients with -alpha/-alpha developed a higher hb concentration than that of the ss (-alpha/alpha alpha), which in turn was higher than that of the ss (alpha alpha/alpha alpha). |
1987-09-18 |
2023-08-11 |
Not clear |
| A E Felice, K M McKie, M P Cleek, E M Marino, A Kutlar, V C McKi. Effects of alpha-thalassemia-2 on the developmental changes of hematological values in children with sickle cell disease from Georgia. American journal of hematology. vol 25. issue 4. 1987-09-18. PMID:2441597. |
the emergence of this difference coincided with a developmental increase of the mean corpuscular hemoglobin concentration (mchc) in patients with ss (alpha alpha/alpha alpha) and the decline of hb f % under 15%. |
1987-09-18 |
2023-08-11 |
Not clear |
| A E Felice, K M McKie, M P Cleek, E M Marino, A Kutlar, V C McKi. Effects of alpha-thalassemia-2 on the developmental changes of hematological values in children with sickle cell disease from Georgia. American journal of hematology. vol 25. issue 4. 1987-09-18. PMID:2441597. |
although the proportion of hb f was independent of alpha globin gene numbers, the absence of hb bart's suggested that alpha-thalassemia promotes the intracellular assembly of hb f over hb s tetramers. |
1987-09-18 |
2023-08-11 |
Not clear |