| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Fodde, M Losekoot, M H van den Broek, M Oldenburg, N Rashida, A Schreuder, J T Wijnen, P C Giordano, N V Nayudu, P M Kha. Prevalence and molecular heterogeneity of alfa+ thalassemia in two tribal populations from Andhra Pradesh, India. Human genetics. vol 80. issue 2. 1988-11-08. PMID:3169739. |
we have confirmed the strict relationship between hb s levels and the number of alpha globin genes in double heterozygotes for the s gene and alpha thalassemia. |
1988-11-08 |
2023-08-11 |
Not clear |
| R Fodde, M Losekoot, M H van den Broek, M Oldenburg, N Rashida, A Schreuder, J T Wijnen, P C Giordano, N V Nayudu, P M Kha. Prevalence and molecular heterogeneity of alfa+ thalassemia in two tribal populations from Andhra Pradesh, India. Human genetics. vol 80. issue 2. 1988-11-08. PMID:3169739. |
in this population sample we did not find either heterozygous carriers of alpha 0 thalassemia (deletion of both alpha genes in "cis") or individuals showing hemolytic anemia due to inactivation of three alpha-globin genes (hb h disease). |
1988-11-08 |
2023-08-11 |
Not clear |
| J M de Pablos, J B Cleg. Hb F-Granada or alpha 2G gamma (2)22(B4)Asp----Val: a new human fetal hemoglobin variant. Hemoglobin. vol 12. issue 4. 1988-11-03. PMID:2459082. |
hb f-granada or alpha 2g gamma (2)22(b4)asp----val: a new human fetal hemoglobin variant. |
1988-11-03 |
2023-08-11 |
human |
| A Kutlar, F Kutlar, J B Wilson, B B Webber, H Hu, T H Huisma. Hb F-Austell or alpha 2G gamma (2)40(C6)Arg----Lys. Hemoglobin. vol 12. issue 4. 1988-11-03. PMID:2459083. |
hb f-austell or alpha 2g gamma (2)40(c6)arg----lys. |
1988-11-03 |
2023-08-11 |
Not clear |
| E N Kosasih, S P Cai, Y W Kan, L E Lie-Inj. Hemoglobin constant spring defined by specific oligonucleotide hybridization and hemoglobin D Punjab (beta 121----Gln) in a Batak Indonesian family. American journal of hematology. vol 29. issue 1. 1988-11-03. PMID:3177365. |
a batak indonesian from north sumatra with hemoglobin (hb) d punjab (alpha 2 beta 2 121----gln) and hemoglobin constant spring (hb cosp) is described. |
1988-11-03 |
2023-08-11 |
Not clear |
| E N Kosasih, S P Cai, Y W Kan, L E Lie-Inj. Hemoglobin constant spring defined by specific oligonucleotide hybridization and hemoglobin D Punjab (beta 121----Gln) in a Batak Indonesian family. American journal of hematology. vol 29. issue 1. 1988-11-03. PMID:3177365. |
the father of propositus who had hb cosp trait gave a positive signal with the normal alpha 2taa oligonucleotide probe as well as with the alpha 2caa oligonucleotide probe, showing him to be heterozygous for the alpha 2caa-globin gene. |
1988-11-03 |
2023-08-11 |
Not clear |
| E N Kosasih, S P Cai, Y W Kan, L E Lie-Inj. Hemoglobin constant spring defined by specific oligonucleotide hybridization and hemoglobin D Punjab (beta 121----Gln) in a Batak Indonesian family. American journal of hematology. vol 29. issue 1. 1988-11-03. PMID:3177365. |
this result shows that the hb cosp in the batak family is indeed due to a replacement of t by c in the taa termination codon of the alpha 2-globin gene changing it to caa the condon for glutamine. |
1988-11-03 |
2023-08-11 |
Not clear |
| K Ishimori, I Morishim. Ruthenium-iron hybrid hemoglobins as a model for partially liganded hemoglobin: NMR studies of their tertiary and quaternary structures. Biochemistry. vol 27. issue 11. 1988-10-18. PMID:3415973. |
diruthenium-substituted ru-fe hybrid hemoglobins (hb) were synthesized by heme substitution from protoheme to ruthenium (ii) carbonyldeuteroporphyrin in the alpha or beta subunits. |
1988-10-18 |
2023-08-11 |
Not clear |
| I Hiebl, R E Weber, D Schneeganss, J Kösters, G Braunitze. High-altitude respiration of birds. Structural adaptations in the major and minor hemoglobin components of adult Rüppell's Griffon (Gyps rueppellii, Aegypiinae): a new molecular pattern for hypoxic tolerance. Biological chemistry Hoppe-Seyler. vol 369. issue 4. 1988-09-21. PMID:3401327. |
the two main components hb a and hb a' differ at position alpha 34 thr/ile. |
1988-09-21 |
2023-08-11 |
Not clear |
| I Hiebl, R E Weber, D Schneeganss, J Kösters, G Braunitze. High-altitude respiration of birds. Structural adaptations in the major and minor hemoglobin components of adult Rüppell's Griffon (Gyps rueppellii, Aegypiinae): a new molecular pattern for hypoxic tolerance. Biological chemistry Hoppe-Seyler. vol 369. issue 4. 1988-09-21. PMID:3401327. |
in case of ile as found in hb a' an alpha 1 beta 1-interface is interrupted raising oxygen affinity compared to hb a. |
1988-09-21 |
2023-08-11 |
Not clear |
| M Castagnola, M Dobosz, R Landolfi, V L Pascali, F de Angelis, L Vettore, G Peron. Determination of neutral haemoglobin variants by immobilized pH gradient, reversed-phase high-performance liquid chromatography and fast-atom bombardment mass spectrometry: the case of a Hb Torino alpha 43 (CE1) Phe----Val. Biological chemistry Hoppe-Seyler. vol 369. issue 4. 1988-09-21. PMID:3401329. |
determination of neutral haemoglobin variants by immobilized ph gradient, reversed-phase high-performance liquid chromatography and fast-atom bombardment mass spectrometry: the case of a hb torino alpha 43 (ce1) phe----val. |
1988-09-21 |
2023-08-11 |
Not clear |
| J Kasten-Jolly, E C Abraha. The cat hemoglobin polymorphism: Southern blot analysis of the beta-globin gene region from cats of various Hb A/Hb B phenotypes. Biochemical genetics. vol 26. issue 3-4. 1988-09-15. PMID:2841921. |
the molecular basis for the genetic control of variable proportions of the two cat hemoglobins hb a(alpha 2 beta a2) and hb b (alpha 2 beta b2) was investigated. |
1988-09-15 |
2023-08-11 |
human |
| V A Spivak, E A Aseeva, I N Lutsenk. [Micropreparative thin-layer peptide maps in the molecular diagnosis of abnormal human hemoglobins]. Molekuliarnaia genetika, mikrobiologiia i virusologiia. issue 4. 1988-09-12. PMID:3405233. |
the results of structural identification of hb d punjab beta 121 glu----gln at a cypriot; hb o arab; beta 121 glu----lys at a bulgarian woman, living in kalinin region (the second case in the ussr); hb m saskatoon beta 63 his----tyr at a woman from georgia (the second case in the ussr); hb buenos aires beta 85 phe----ser at a russian girl (the first case in the ussr and the third case in the world); hb dagestan alpha 60 lys----glu at two members of a lesgin family from dagestan; hb agenogi beta 90 glu----lys at a hungarian woman; hb setif alpha 94 asp----tyr at three patients from cyprus and hb detroit beta 95 lys----asn at an azerbaijanian woman (the first case in the ussr and the second case in the world) are presented. |
1988-09-12 |
2023-08-11 |
human |
| J G Gilman, N Mishima, X J Wen, F Kutlar, T H Huisma. Upstream promoter mutation associated with a modest elevation of fetal hemoglobin expression in human adults. Blood. vol 72. issue 1. 1988-08-19. PMID:2455576. |
in hereditary persistence of fetal hemoglobin, hb f (alpha 2 gamma 2) is elevated after birth. |
1988-08-19 |
2023-08-11 |
human |
| K Kitagishi, C D'Ambrosio, T Yonetan. Electron paramagnetic resonance study on crosslinked asymmetric Fe(II)-Co(II) hybrids of hemoglobin. Archives of biochemistry and biophysics. vol 264. issue 1. 1988-08-19. PMID:2840023. |
the epr signal of the alpha (co) ion is sensitive to the release of alkaline bohr proton(s) and consequently to the allosteric quaternary structural change of hb. |
1988-08-19 |
2023-08-11 |
Not clear |
| F A Garver, H Moscoso, S Swamy, C R Kiefe. Generation of a monoclonal antibody specific for Hb G-Philadelphia [alpha 2(68)(E17)Asn----Lys beta 2] and development of an immunoassay. Hemoglobin. vol 12. issue 2. 1988-08-09. PMID:3384705. |
generation of a monoclonal antibody specific for hb g-philadelphia [alpha 2(68)(e17)asn----lys beta 2] and development of an immunoassay. |
1988-08-09 |
2023-08-11 |
mouse |
| F A Garver, H Moscoso, S Swamy, C R Kiefe. Generation of a monoclonal antibody specific for Hb G-Philadelphia [alpha 2(68)(E17)Asn----Lys beta 2] and development of an immunoassay. Hemoglobin. vol 12. issue 2. 1988-08-09. PMID:3384705. |
a murine hybridoma was generated which secreted a monoclonal antibody (mab) that specifically recognized the alpha 2(68)(e17)asn----lys beta 2 substitution of hb g-philadelphia. |
1988-08-09 |
2023-08-11 |
mouse |
| J J Malcorra-Azpiazu, M I Balda-Aguirre, J C Diaz-Chico, H Hu, J B Wilson, B B Webber, F Kutlar, A Kutlar, T H Huisma. Hb Las Palmas or alpha 2 beta 2(49)(CD8)Ser----Phe, a mildly unstable hemoglobin variant. Hemoglobin. vol 12. issue 2. 1988-08-09. PMID:3384708. |
hb las palmas or alpha 2 beta 2(49)(cd8)ser----phe, a mildly unstable hemoglobin variant. |
1988-08-09 |
2023-08-11 |
Not clear |
| V Baudin-Chich, H Wajcman, G Gombaud-Saintonge, N Arous, J Riou, J Brière, F Galactero. Hemoglobin Brest [beta 127 (H5)Gln----Lys] a new unstable human hemoglobin variant located at the alpha 1 beta 1 interface with specific electrophoretic behavior. Hemoglobin. vol 12. issue 2. 1988-08-09. PMID:3384710. |
hb brest [beta 127 (h5)gln----lys] is a new unstable variant located at the alpha 1 beta 1 interface at the same position as hb complutense [beta 127(h5)gln----glu]. |
1988-08-09 |
2023-08-11 |
human |
| J J Malcorra-Azpiazu, M I Balda-Aguirre, J C Diaz-Chico, F Kutlar, A Kutlar, J B Wilson, H Hu, T H Huisma. Hb Le Lamentin or alpha 2 20(B1)His----GLN beta 2 found in a Spanish family. Hemoglobin. vol 12. issue 2. 1988-08-09. PMID:3384713. |
hb le lamentin or alpha 2 20(b1)his----gln beta 2 found in a spanish family. |
1988-08-09 |
2023-08-11 |
Not clear |