| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R E Benesch, S Kwon. The stability of the heme-globin linkage in some normal, mutant, and chemically modified hemoglobins. The Journal of biological chemistry. vol 265. issue 25. 1990-10-09. PMID:1697581. |
taken together with the finding that the rate was 10 times greater for hb rothschild, which is completely dissociated into alpha beta dimers and 10 times smaller for two cross-linked hemoglobins, the subunits of which cannot dissociate, this showed that the rate of dissociation of heme from alpha beta dimers is very much greater than from tetramers. |
1990-10-09 |
2023-08-11 |
human |
| S H Lin, N T Yu, J Tame, D Shih, J P Renaud, J Pagnier, K Naga. Effect of the distal residues on the vibrational modes of the Fe-CO bond in hemoglobin studied by protein engineering. Biochemistry. vol 29. issue 23. 1990-09-27. PMID:2201408. |
the replacement of val-e11 by ala, leu, ile, and met has no effect on the v(c-o), v(fe-co) stretching or delta(fe-c-o) bending frequencies in both the alpha and beta subunits of hb, although some of these mutations affect the co affinity as much as 40-fold. |
1990-09-27 |
2023-08-11 |
human |
| G Martín, A Villegas, F Calero, S del Palacio, J C López, M López, D Espinó. Hb O Padova in a Spanish Family. Acta haematologica. vol 84. issue 1. 1990-09-20. PMID:2117321. |
haematological and biochemical aspects of a new family with heterozygous hb o padova [alpha 30(b11) glu----lys] is described. |
1990-09-20 |
2023-08-11 |
Not clear |
| J Hundrieser, T Sanguansermsri, M Laig, M Pape, W Kühnau, G Flat. Direct demonstration of the HB Suan-Dok mutation in the alpha 2-globin gene by restriction analysis with Sma I. Hemoglobin. vol 14. issue 1. 1990-09-14. PMID:2384313. |
direct demonstration of the hb suan-dok mutation in the alpha 2-globin gene by restriction analysis with sma i. hb suan-dok [alpha 2(109)(g16)leu-greater than arg beta 2] has an alpha-thalassemia-like effect due to low production and instability of the altered alpha-globin chain. |
1990-09-14 |
2023-08-11 |
Not clear |
| G V Sciarratta, G Ivald. Hb Matera [beta 55(D6)Met----Lys]: a new unstable hemoglobin variant in an Italian family. Hemoglobin. vol 14. issue 1. 1990-09-14. PMID:2384314. |
hb matera's instability is due to an interference in the alpha 1-beta 1 contact of the hemoglobin molecule. |
1990-09-14 |
2023-08-11 |
Not clear |
| [Analysis of a program for atypical familial microcytosis. Molecular basis for alpha-thalassemia. GEHBTA]. Sangre. vol 35. issue 2. 1990-08-08. PMID:2363092. |
of the 98 patients, 3 had hb h disease, 70 corresponded to heterozygous alpha zero-thalassaemia, 11 to homozygous alpha(+)-thalassaemia, and 14 to heterozygous alpha(+)-thalassaemia. |
1990-08-08 |
2023-08-11 |
Not clear |
| C Oner, A Gurgey, C Altay, F Kutlar, T H Huisma. Variation in the level of fetal hemoglobin in (delta beta) (0)-thalassemia heterozygotes with different numbers of alpha-globin genes. American journal of hematology. vol 34. issue 3. 1990-08-07. PMID:1694630. |
the father with approximately 21% hb f had five alpha-globin genes (alpha alpha/alpha alpha alpha) and the mother with approximately 10% hb f had an alpha-thal-2 heterozygosity (alpha alpha/-alpha). |
1990-08-07 |
2023-08-11 |
Not clear |
| C Oner, A Gurgey, C Altay, F Kutlar, T H Huisma. Variation in the level of fetal hemoglobin in (delta beta) (0)-thalassemia heterozygotes with different numbers of alpha-globin genes. American journal of hematology. vol 34. issue 3. 1990-08-07. PMID:1694630. |
the difference in hb f level is explained by a decreased formation of alpha 2 gamma 2 tetramers in the mother with an alpha-chain deficiency while the extra alpha-globin gene in the father will promote hb f production. |
1990-08-07 |
2023-08-11 |
Not clear |
| R D'Avino, C Caruso, M E Schinina, B Rutigliano, M Romano, L Camardella, F Bossa, D Barra, G di Prisc. Hemoglobin from the antarctic fish Notothenia coriiceps neglecta. Amino acid sequence of the beta chain. Comparative biochemistry and physiology. B, Comparative biochemistry. vol 96. issue 2. 1990-08-07. PMID:2361365. |
the two components differ by the alpha chain; the amino acid sequence of the beta chain in common to the two hemoglobins has been established, thus completing the elucidation of the primary structure of the major component hb 1. |
1990-08-07 |
2023-08-11 |
Not clear |
| A Bellelli, R Ippoliti, A Brancaccio, E Lendaro, M Brunor. Cooperative ligand binding of crosslinked hemoglobins at very high temperatures. Journal of molecular biology. vol 213. issue 4. 1990-08-01. PMID:2359113. |
human hemoglobin was reacted with the bifunctional reagent bis(3,5-dibromosalicyl) fumarate to yield a derivative (hb alpha alpha) crosslinked between the two alpha-chains; when the reaction was carried out with hba already crosslinked between the two beta-chains by 2-nor-2-formylpyridoxal 5'-phosphate, a doubly crosslinked derivative (hb alpha alpha beta beta) was obtained. |
1990-08-01 |
2023-08-11 |
human |
| H Wajcman, Y Blouquit, J Riou, J Kister, C Poyart, J Soria, F Galactero. A new hemoglobin variant found during investigations of diabetes mellitus: Hb Pavie [alpha 135 (H18) Val----Glu]. Clinica chimica acta; international journal of clinical chemistry. vol 188. issue 1. 1990-07-12. PMID:2347082. |
a new hemoglobin variant found during investigations of diabetes mellitus: hb pavie [alpha 135 (h18) val----glu]. |
1990-07-12 |
2023-08-11 |
Not clear |
| H Wajcman, Y Blouquit, J Riou, J Kister, C Poyart, J Soria, F Galactero. A new hemoglobin variant found during investigations of diabetes mellitus: Hb Pavie [alpha 135 (H18) Val----Glu]. Clinica chimica acta; international journal of clinical chemistry. vol 188. issue 1. 1990-07-12. PMID:2347082. |
hb pavie [alpha 135 (h18) val----glu], found during hba1c measurement in a patient of italian origin investigated for diabetes mellitus, exemplifies how the presence of an abnormal hemoglobin interferes with the measurement of glycated hemoglobin. |
1990-07-12 |
2023-08-11 |
Not clear |
| F Marongiu, M Conti, G Mameli, G G Sorano, E Cossu, R Cirillo, A Balestrier. Is the imbalance between thrombin and plasmin activity in diabetes related to the behaviour of antiplasmin activity? Thrombosis research. vol 58. issue 2. 1990-07-11. PMID:1693451. |
a non linear correlation was found between hb a1c and alpha 2 ap in both diabetic groups. |
1990-07-11 |
2023-08-11 |
Not clear |
| J Pagnier, V Baudin-Chich, N Lacaze, B Bohn, C Poyar. Haemoglobin alpha 2 beta 2 23Val----Ile produced in Escherichia coli facilitates Hb S polymerization. British journal of haematology. vol 74. issue 4. 1990-07-11. PMID:2189492. |
haemoglobin alpha 2 beta 2 23val----ile produced in escherichia coli facilitates hb s polymerization. |
1990-07-11 |
2023-08-11 |
Not clear |
| J Pagnier, V Baudin-Chich, N Lacaze, B Bohn, C Poyar. Haemoglobin alpha 2 beta 2 23Val----Ile produced in Escherichia coli facilitates Hb S polymerization. British journal of haematology. vol 74. issue 4. 1990-07-11. PMID:2189492. |
the csat value for pure deoxyhb s-antilles is nearly half that of deoxyhb s. dilute solutions of pure hb s-antilles have a lower oxygen affinity than those of hb a or hb s. the mutant hb alpha 2 beta 2 23 val----ile was synthesized in e. coli. |
1990-07-11 |
2023-08-11 |
Not clear |
| B E Glader, D Zwerdling, F Kutlar, A Kutlar, J B Wilson, T H Huisma. Hb F-M-Osaka or alpha 2G gamma 2(63)(E7)His----Tyr in a Caucasian male infant. Hemoglobin. vol 13. issue 7-8. 1990-06-07. PMID:2483933. |
hb f-m-osaka or alpha 2g gamma 2(63)(e7)his----tyr in a caucasian male infant. |
1990-06-07 |
2023-08-11 |
Not clear |
| Y Ohba, K Imai, R Uenaka, M Ami, K Fujisawa, K Itoh, K Hirakawa, T Miyaj. Hb Miyano or alpha 41(C6)Thr----Ser: a new high oxygen affinity alpha chain variant found in an erythremic blood donor. Hemoglobin. vol 13. issue 7-8. 1990-06-07. PMID:2634665. |
hb miyano or alpha 41(c6)thr----ser: a new high oxygen affinity alpha chain variant found in an erythremic blood donor. |
1990-06-07 |
2023-08-11 |
Not clear |
| Y Ohba, K Imai, R Uenaka, M Ami, K Fujisawa, K Itoh, K Hirakawa, T Miyaj. Hb Miyano or alpha 41(C6)Thr----Ser: a new high oxygen affinity alpha chain variant found in an erythremic blood donor. Hemoglobin. vol 13. issue 7-8. 1990-06-07. PMID:2634665. |
an abnormal hemoglobin found in an erythremic blood donor was separable only by isoelectrofocusing, where it was located at the cathodic edge of hb a. cation exchange high performance liquid chromatography of a tryptic digest from the total alpha chain revealed splitting of the alpha t-6 peak, although our routine procedures failed to uncover the abnormality. |
1990-06-07 |
2023-08-11 |
Not clear |
| J Bardakdjian-Michau, J Rosa, F Galactéros, M Lancelot, F X Marquar. Hb Reims [alpha 2(23)(B4)Glu----Gly beta 2]: a new alpha chain variant with slightly decreased stability. Hemoglobin. vol 13. issue 7-8. 1990-06-07. PMID:2634669. |
hb reims [alpha 2(23)(b4)glu----gly beta 2]: a new alpha chain variant with slightly decreased stability. |
1990-06-07 |
2023-08-11 |
Not clear |
| M Z Abd. Hb Setif [alpha 94(G1)Asp----Tyr] in a Saudi Arabian family. Hemoglobin. vol 13. issue 7-8. 1990-06-07. PMID:2634670. |
hb setif [alpha 94(g1)asp----tyr] in a saudi arabian family. |
1990-06-07 |
2023-08-11 |
Not clear |