| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Thonglairoam, P Winichagoon, S Fucharoen, V S Tanphaichitr, P Pung-amritt, S H Embury, P Was. Hemoglobin constant spring in Bangkok: molecular screening by selective enzymatic amplification of the alpha 2-globin gene. American journal of hematology. vol 38. issue 4. 1992-01-13. PMID:1746536. |
selective enzymatic amplification of the alpha 2-globin gene and allele-specific hybridization for hb cs gene provided accurate diagnosis of hb constant spring. |
1992-01-13 |
2023-08-11 |
human |
| V Thonglairoam, P Winichagoon, S Fucharoen, V S Tanphaichitr, P Pung-amritt, S H Embury, P Was. Hemoglobin constant spring in Bangkok: molecular screening by selective enzymatic amplification of the alpha 2-globin gene. American journal of hematology. vol 38. issue 4. 1992-01-13. PMID:1746536. |
we have used this approach to detect the alpha cs mutation in the cord blood that contained all four alpha-globin genes but had hb bart on electrophoresis. |
1992-01-13 |
2023-08-11 |
human |
| V Thonglairoam, P Winichagoon, S Fucharoen, V S Tanphaichitr, P Pung-amritt, S H Embury, P Was. Hemoglobin constant spring in Bangkok: molecular screening by selective enzymatic amplification of the alpha 2-globin gene. American journal of hematology. vol 38. issue 4. 1992-01-13. PMID:1746536. |
the alpha cs mutation was found in six subjects whose hb bart levels were 3.0, 3.2, 3.7, 4.0, 4.9, and 9.8%. |
1992-01-13 |
2023-08-11 |
human |
| V Thonglairoam, P Winichagoon, S Fucharoen, V S Tanphaichitr, P Pung-amritt, S H Embury, P Was. Hemoglobin constant spring in Bangkok: molecular screening by selective enzymatic amplification of the alpha 2-globin gene. American journal of hematology. vol 38. issue 4. 1992-01-13. PMID:1746536. |
the latter also had -alpha mutation on the other chromosome, giving rise to the genotype alpha cs alpha/-alpha, which produced high hb bart. |
1992-01-13 |
2023-08-11 |
human |
| Y Ohba, K Yamamoto, Y Hattori, K Yamamoto, T Miyaji, F Shiosaki, H Mori, K Yamaguchi, M Takahashi, H Mizoguch. Further cases of Hb Hirosaki in two Japanese families. International journal of hematology. vol 54. issue 1. 1992-01-02. PMID:1954347. |
hb hirosaki (alpha 43(ce1)phe----leu) was recently found anew in two japanese families. |
1992-01-02 |
2023-08-11 |
human |
| M Trudel, N Saadane, M C Garel, J Bardakdjian-Michau, Y Blouquit, J L Guerquin-Kern, P Rouyer-Fessard, D Vidaud, A Pachnis, P H Romé. Towards a transgenic mouse model of sickle cell disease: hemoglobin SAD. The EMBO journal. vol 10. issue 11. 1991-11-18. PMID:1915288. |
in one of the five transgenic lines obtained, sad-1, red blood cells contained 19% human hb sad (alpha 2 human 1 beta 2sad) and mouse-human hybrids in addition to mouse hemoglobin. |
1991-11-18 |
2023-08-11 |
mouse |
| K Adachi, J Kim, N Shibayam. Polymerization and solubility of Ni(II)-Fe(II) hybrid Hb S. Biochimica et biophysica acta. vol 1079. issue 3. 1991-11-08. PMID:1911850. |
polymerization and solubility of ni(ii)-fe(ii) hybrid hb s. polymerization of half-liganded hb s was investigated using ni(ii)-fe(ii) hybrid hb s, in which heme in either alpha or beta s subunits is replaced by ni (ii) protoporphyrin ix. |
1991-11-08 |
2023-08-11 |
Not clear |
| K Adachi, J Kim, N Shibayam. Polymerization and solubility of Ni(II)-Fe(II) hybrid Hb S. Biochimica et biophysica acta. vol 1079. issue 3. 1991-11-08. PMID:1911850. |
both alpha 2 (ni) beta 2s (fe-co) and alpha 2 (fe-co) beta 2s (ni) polymerized with a distinct delay time as do native deoxy-hb s and ni(ii) hb s. however, the critical concentration for polymerization of half-liganded hb s, alpha 2 (ni) beta 2s (fe-co) and alpha 2 (fe-co) beta 2s (ni), was 4- and 8-times higher, respectively, than that of ni(ii)-hb s. kinetics of polymerization of both deoxygenated hybrid hemoglobins with co completely removed were the same, although the critical concentrations for polymerization were intermediate between those for deoxy-hb s and ni(ii)-hb s. these results suggest that the small tertiary conformational change associated with the doubly liganded state may be much less favorable to polymerization than the completely unliganded state of hb s. the conformational change depends on whether alpha or beta chain is liganded. |
1991-11-08 |
2023-08-11 |
Not clear |
| J Lavinha, P Faustino, L Osório-Almeida, Y Hattori, Y Ohba, M C Martin. Hb Himeji [alpha 2 beta 2(140)(H18)Ala----Asp] is linked to different haplotypes in Japanese and Portuguese families. Hemoglobin. vol 15. issue 1-2. 1991-10-31. PMID:1680833. |
hb himeji [alpha 2 beta 2(140)(h18)ala----asp] is linked to different haplotypes in japanese and portuguese families. |
1991-10-31 |
2023-08-11 |
Not clear |
| C Vasseur, A Francina, H Wajcman, F Galactéro. Two new cases of Hb Denmark Hill [alpha 95(G2)Pro----Ala] discovered in south-west France: electrophoretical and chromatographical considerations. Hemoglobin. vol 15. issue 1-2. 1991-10-31. PMID:1917529. |
two new cases of hb denmark hill [alpha 95(g2)pro----ala] discovered in south-west france: electrophoretical and chromatographical considerations. |
1991-10-31 |
2023-08-11 |
Not clear |
| K Indrak, V Brabec, J B Wilson, B B Webber, T H Huisma. Hb Köln or alpha 2 beta 2(98)(FG5)Val----Met in a Czechoslovakian family. Hemoglobin. vol 15. issue 1-2. 1991-10-31. PMID:1917535. |
hb köln or alpha 2 beta 2(98)(fg5)val----met in a czechoslovakian family. |
1991-10-31 |
2023-08-11 |
Not clear |
| W F Moo-Penn, T K Hine, M H Johnson, D L Jue, H Piersma, B Therrell, A Ch. Hb Luxembourg [alpha 24(B5)Tyr----His], Hb Maputo [beta 47(CD6)Asp----Tyr], and Hb Fukuyama [beta 77(EF1)His----Tyr]. Hemoglobin. vol 15. issue 1-2. 1991-10-31. PMID:1917540. |
hb luxembourg [alpha 24(b5)tyr----his], hb maputo [beta 47(cd6)asp----tyr], and hb fukuyama [beta 77(ef1)his----tyr]. |
1991-10-31 |
2023-08-11 |
Not clear |
| J A Ta. An evaluation of the polymerase chain reaction for detection of alpha-globin genes in the prenatal diagnosis of alpha zero-thalassaemia. Annals of the Academy of Medicine, Singapore. vol 20. issue 2. 1991-09-30. PMID:1883186. |
confirmation of alpha zero-thalassaemia by dna gene mapping and electrophoresis of cord blood showed absence of alpha-globin genes and only hb bart's respectively. |
1991-09-30 |
2023-08-11 |
Not clear |
| S C Wong, M Tesanovic, M C Poo. Detection of two abnormal hemoglobins, Hb Manitoba and Hb G-Coushatta, during analysis of glycohemoglobin (A1c) by high-performance liquid chromatography. Clinical chemistry. vol 37. issue 8. 1991-09-19. PMID:1868612. |
structural studies determined the two hb variants to be hb manitoba (alpha 2 102 ser----arg beta 2) and hb g-coushatta (alpha 2 beta 2 22 glu----ala). |
1991-09-19 |
2023-08-11 |
Not clear |
| G Sahni, A K Mallia, A S Achary. Proteosynthetic activity of immobilized Staphylococcus aureus V8 protease: application in the semisynthesis of molecular variants of alpha-globin. Analytical biochemistry. vol 193. issue 2. 1991-09-19. PMID:1872464. |
the complementary fragments from two natural mutant forms of alpha-globin, viz., alpha 1-30 (k16e) from hb i and alpha 31-141 (d47h) from hb sealy, are readily ligated to form the double mutant alpha 1-141 (k16e;d47h). |
1991-09-19 |
2023-08-11 |
Not clear |
| J A Tan, S H Tay, O K Siang, P S Lai, W H Boon, S Kha. Prenatal diagnosis of alpha- and beta-thalassaemias in Singapore--current status. Annals of tropical paediatrics. vol 11. issue 1. 1991-09-18. PMID:1714698. |
homozygous alpha (0)-thalassaemia was detected in four fetuses and the results were subsequently confirmed by electrophoresis of the cord blood where only hb barts was detected. |
1991-09-18 |
2023-08-11 |
Not clear |
| W Zhao, J B Wilson, B B Webber, A Kutlar, G P Tamagnini, B Kuam, T H Huisma. Hb Hekinan observed in three Chinese from Macau; identification of the GAG----GAT mutation in the alpha 1-globin gene. Hemoglobin. vol 14. issue 6. 1991-09-16. PMID:1983218. |
hb hekinan observed in three chinese from macau; identification of the gag----gat mutation in the alpha 1-globin gene. |
1991-09-16 |
2023-08-11 |
Not clear |
| W Zhao, J B Wilson, B B Webber, A Kutlar, G P Tamagnini, B Kuam, T H Huisma. Hb Hekinan observed in three Chinese from Macau; identification of the GAG----GAT mutation in the alpha 1-globin gene. Hemoglobin. vol 14. issue 6. 1991-09-16. PMID:1983218. |
hb hekinan, an alpha chain variant that is characterized by a glu----asp mutation at position alpha 27, was observed in three chinese females attending a prenatal clinic in macau. |
1991-09-16 |
2023-08-11 |
Not clear |
| J B Wilson, B B Webber, D Plaseska, P A de Alarcon, S K McMillan, T H Huisma. Hb Davenport or alpha 2(78)(EF7)Asn----His beta 2. Hemoglobin. vol 14. issue 6. 1991-09-16. PMID:2101836. |
hb davenport or alpha 2(78)(ef7)asn----his beta 2. |
1991-09-16 |
2023-08-11 |
Not clear |
| J B Wilson, B B Webber, D Plaseska, P A de Alarcon, S K McMillan, T H Huisma. Hb Davenport or alpha 2(78)(EF7)Asn----His beta 2. Hemoglobin. vol 14. issue 6. 1991-09-16. PMID:2101836. |
hb davenport is a new, stable alpha chain variant, that was detected in two members of a caucasian family living in iowa. |
1991-09-16 |
2023-08-11 |
Not clear |