| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J H Helderman, D Elahi, D K Andersen, G S Raizes, J D Tobin, D Shocken, R Andre. Prevention of the glucose intolerance of thiazide diuretics by maintenance of body potassium. Diabetes. vol 32. issue 2. 1983-04-15. PMID:6337892. |
serial insulin (iri) and gastric inhibitory polypeptide (gip) levels were measured as well as the level of glucose infusion necessary to maintain the stable hyperglycemic level. |
1983-04-15 |
2023-08-12 |
human |
| J H Helderman, D Elahi, D K Andersen, G S Raizes, J D Tobin, D Shocken, R Andre. Prevention of the glucose intolerance of thiazide diuretics by maintenance of body potassium. Diabetes. vol 32. issue 2. 1983-04-15. PMID:6337892. |
when potassium losses were prevented, thiazides induced no alterations in glucose tolerance, beta-cell sensitivity to glucose, gip-cell sensitivity to glucose, beta-cell sensitivity to gip, or tissue sensitivity to insulin. |
1983-04-15 |
2023-08-12 |
human |
| B Ahrén, P Hedner, I Lundquis. Interaction of gastric inhibitory polypeptide (GIP) and cholecystokinin (CCK-8) with basal and stimulated insulin secretion in mice. Acta endocrinologica. vol 102. issue 1. 1983-03-24. PMID:6130663. |
interaction of gastric inhibitory polypeptide (gip) and cholecystokinin (cck-8) with basal and stimulated insulin secretion in mice. |
1983-03-24 |
2023-08-12 |
mouse |
| B Ahrén, P Hedner, I Lundquis. Interaction of gastric inhibitory polypeptide (GIP) and cholecystokinin (CCK-8) with basal and stimulated insulin secretion in mice. Acta endocrinologica. vol 102. issue 1. 1983-03-24. PMID:6130663. |
the interaction of gip and cck-8 with basal insulin secretion and with insulin release induced by glucose or by the beta-adrenoceptor agonist l-isopropylnoradrenaline (l-ipna) was studied in mice. |
1983-03-24 |
2023-08-12 |
mouse |
| B Ahrén, P Hedner, I Lundquis. Interaction of gastric inhibitory polypeptide (GIP) and cholecystokinin (CCK-8) with basal and stimulated insulin secretion in mice. Acta endocrinologica. vol 102. issue 1. 1983-03-24. PMID:6130663. |
gip and cck-8, when injected in threshold doses not affecting basal insulin secretion, did markedly enhance basal insulin release when given simultaneously. |
1983-03-24 |
2023-08-12 |
mouse |
| B Ahrén, P Hedner, I Lundquis. Interaction of gastric inhibitory polypeptide (GIP) and cholecystokinin (CCK-8) with basal and stimulated insulin secretion in mice. Acta endocrinologica. vol 102. issue 1. 1983-03-24. PMID:6130663. |
insulin release induced by a half-maximal dose of glucose was slightly potentiated by the threshold dose of gip and markedly potentiated by the maximal dose i.e. |
1983-03-24 |
2023-08-12 |
mouse |
| B Ahrén, P Hedner, I Lundquis. Interaction of gastric inhibitory polypeptide (GIP) and cholecystokinin (CCK-8) with basal and stimulated insulin secretion in mice. Acta endocrinologica. vol 102. issue 1. 1983-03-24. PMID:6130663. |
the combination of gip and cck-8 did not display the potentiating effect of gip alone on glucose-stimulated insulin release. |
1983-03-24 |
2023-08-12 |
mouse |
| B Ahrén, P Hedner, I Lundquis. Interaction of gastric inhibitory polypeptide (GIP) and cholecystokinin (CCK-8) with basal and stimulated insulin secretion in mice. Acta endocrinologica. vol 102. issue 1. 1983-03-24. PMID:6130663. |
insulin release stimulated by a half-maximal dose of l-ipna was not affected by either gip or cck-8 at the threshold doses. |
1983-03-24 |
2023-08-12 |
mouse |
| B Ahrén, P Hedner, I Lundquis. Interaction of gastric inhibitory polypeptide (GIP) and cholecystokinin (CCK-8) with basal and stimulated insulin secretion in mice. Acta endocrinologica. vol 102. issue 1. 1983-03-24. PMID:6130663. |
similarly, at the high dose level of the peptides, the combination of gip plus cck-8 and l-ipna as well as cck-8 alone plus l-ipna displayed a lower insulin response than that expected from an additive effect. |
1983-03-24 |
2023-08-12 |
mouse |
| A J McCullough, L J Miller, F J Service, V L G. Effect of graded intraduodenal glucose infusions on the release and physiological action of gastric inhibitory polypeptide. The Journal of clinical endocrinology and metabolism. vol 56. issue 2. 1983-03-11. PMID:6337173. |
gastric inhibitory polypeptide (gip) is the leading candidate for gut hormonal augmentation of insulin release. |
1983-03-11 |
2023-08-12 |
human |
| J M Falko, J C Reynolds, T M O'Dorisio, B Bossetti, S Catalan. The role of gastric inhibitory polypeptide in the augmented insulin response to sucrose. Diabetes care. vol 5. issue 4. 1983-03-11. PMID:6759077. |
to evaluate the role of gastric inhibitory polypeptide (gip) in the augmented insulin response to sucrose, seven normal volunteers ingested four separate meals of 100 g sucrose (s), 50 g glucose (g), 50 g fructose (f), and 50 g glucose + 50 g fructose (g + f). |
1983-03-11 |
2023-08-12 |
human |
| J M Falko, J C Reynolds, T M O'Dorisio, B Bossetti, S Catalan. The role of gastric inhibitory polypeptide in the augmented insulin response to sucrose. Diabetes care. vol 5. issue 4. 1983-03-11. PMID:6759077. |
serum insulin, glucose, and gip were measured. |
1983-03-11 |
2023-08-12 |
human |
| J M Falko, J C Reynolds, T M O'Dorisio, B Bossetti, S Catalan. The role of gastric inhibitory polypeptide in the augmented insulin response to sucrose. Diabetes care. vol 5. issue 4. 1983-03-11. PMID:6759077. |
although significant insulin and glucose responses to (f) occurred in hour 1, g + f led to insulin and glucose responses similar to g. g + f led to greater gip levels than g in hour 3. |
1983-03-11 |
2023-08-12 |
human |
| J M Falko, J C Reynolds, T M O'Dorisio, B Bossetti, S Catalan. The role of gastric inhibitory polypeptide in the augmented insulin response to sucrose. Diabetes care. vol 5. issue 4. 1983-03-11. PMID:6759077. |
these studies show that gip may play a role in the augmented insulin response to s in hours 2 and 3. |
1983-03-11 |
2023-08-12 |
human |
| J M Falko, J C Reynolds, T M O'Dorisio, B Bossetti, S Catalan. The role of gastric inhibitory polypeptide in the augmented insulin response to sucrose. Diabetes care. vol 5. issue 4. 1983-03-11. PMID:6759077. |
the augmentation of insulin to s in the first hour may result from fructose, extra glucose equivalent of the sucrose test solution, or from endocrine mechanisms other than those subserved by gip. |
1983-03-11 |
2023-08-12 |
human |
| M Salera, P Giacomoni, L Pironi, C Ustra, M Capelli, A Giorgi, M Miglioli, L Barbar. Circadian rhythm of gastric inhibitory polypeptide (GIP) in man. Metabolism: clinical and experimental. vol 32. issue 1. 1983-02-25. PMID:6336815. |
the diurnal variations of serum gastric inhibitory polypeptide (gip), serum insulin, plasma glucagon, plasma glucose and serum triglycerides were studied for 24 hr in 6 healthy young men, consuming three meals and performing their usual physical activities. |
1983-02-25 |
2023-08-12 |
Not clear |
| N A Sysoeva, R G Oganov, I L Mikhaĭlov. [Metabolic effects of a glucose-insulin-potassium mixture in acute myocardial infarct]. Kardiologiia. vol 22. issue 10. 1983-02-14. PMID:6757523. |
in order to limit the spread of myocardial infarction, 56 patients with acute myocardial infarction, admitted to hospital within 10 hours from the attack, were for two days treated with continuous intravenous drip infusion of glucose-insulin-potassium mixture (gip) (300 ml glucose, 50 u common insulin, 60 meqv potassium chloride at the rate of 1 ml/kg/hour). |
1983-02-14 |
2023-08-12 |
Not clear |
| B Ahrén, I Lundquis. Influence of glucagon, gastric inhibitory polypeptide, pancreatic polypeptide and somatostatin on beta-adrenergically induced insulin secretion in the mouse. Diabete & metabolisme. vol 8. issue 3. 1983-01-27. PMID:6128264. |
the effect of four polypeptides, glucagon, gastric inhibitory polypeptide (gip), pancreatic polypeptide (pp) and somatostatin on beta-adrenoceptor stimulated insulin secretion in vivo in the mouse was investigated. |
1983-01-27 |
2023-08-12 |
mouse |
| B Ahrén, I Lundquis. Influence of glucagon, gastric inhibitory polypeptide, pancreatic polypeptide and somatostatin on beta-adrenergically induced insulin secretion in the mouse. Diabete & metabolisme. vol 8. issue 3. 1983-01-27. PMID:6128264. |
gip and pp did not change ipna-induced insulin release. |
1983-01-27 |
2023-08-12 |
mouse |
| B Ahrén, I Lundquis. Influence of glucagon, gastric inhibitory polypeptide, pancreatic polypeptide and somatostatin on beta-adrenergically induced insulin secretion in the mouse. Diabete & metabolisme. vol 8. issue 3. 1983-01-27. PMID:6128264. |
it is concluded from this and earlier published studies that glucagon, but not always gip, serves as a positive modulator of basal and stimulated insulin secretion, and that somatostatin is a general inhibitor of insulin release. |
1983-01-27 |
2023-08-12 |
mouse |