| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J C Brown, M Dahl, S Kwauk, C H McIntosh, S C Otte, R A Pederso. Actions of GIP. Peptides. vol 2 Suppl 2. 1982-08-14. PMID:7045829. |
gip was also shown to potentiate insulin release initiated by d-glyceraldehyde, l-leucine/l-glutamine and 2-keto-isocaproic acid. |
1982-08-14 |
2023-08-12 |
Not clear |
| J Arendt, S Hampton, J English, P Kwasowski, V Mark. 24-hour profiles of melatonin, cortisol, insulin, C-peptide and GIP following a meal and subsequent fasting. Clinical endocrinology. vol 16. issue 1. 1982-07-19. PMID:7042131. |
24-hour profiles of melatonin, cortisol, insulin, c-peptide and gip following a meal and subsequent fasting. |
1982-07-19 |
2023-08-12 |
human |
| J Arendt, S Hampton, J English, P Kwasowski, V Mark. 24-hour profiles of melatonin, cortisol, insulin, C-peptide and GIP following a meal and subsequent fasting. Clinical endocrinology. vol 16. issue 1. 1982-07-19. PMID:7042131. |
melatonin, free and total cortisol, insulin, c-peptide and glucose-dependent insulin-releasing peptide (gip) were measured in the plasma of twelve normal volunteers (eight women and four men), at hourly intervals for 24 h following a meal and subsequent fasting. |
1982-07-19 |
2023-08-12 |
human |
| D Elahi, G S Raizes, R Andres, R J Hershcopf, D C Muller, J D Tobin, D K Anderse. Interaction of arginine and gastric inhibitory polypeptide on insulin release in man. The American journal of physiology. vol 242. issue 5. 1982-07-08. PMID:7044143. |
the interrelations of the insulin secretagogues, glucose, arginine (arg), and gastric inhibitory polypeptide (gip) were quantified in six normal young men in five sets of experiments with the hyperglycemic clamp technique (125 mg/dl above basal glucose levels for 2 h). |
1982-07-08 |
2023-08-12 |
Not clear |
| b' J Szec\\xc3\\xb3wka, V Grill, E Sandberg, S Efendi\\xc4\\x8. Effect of GIP on the secretion of insulin and somatostatin and the accumulation of cyclic AMP in vitro in the rat. Acta endocrinologica. vol 99. issue 3. 1982-06-21. PMID:6122321.' |
effect of gip on the secretion of insulin and somatostatin and the accumulation of cyclic amp in vitro in the rat. |
1982-06-21 |
2023-08-12 |
rat |
| b' J Szec\\xc3\\xb3wka, V Grill, E Sandberg, S Efendi\\xc4\\x8. Effect of GIP on the secretion of insulin and somatostatin and the accumulation of cyclic AMP in vitro in the rat. Acta endocrinologica. vol 99. issue 3. 1982-06-21. PMID:6122321.' |
the effects of gastric inhibitory polypeptide (gip) on insulin secretion as well as on the intra-islet accumulation of [3h]cyclic amp were investigated in isolated pancreatic islets of the rat. |
1982-06-21 |
2023-08-12 |
rat |
| b' J Szec\\xc3\\xb3wka, V Grill, E Sandberg, S Efendi\\xc4\\x8. Effect of GIP on the secretion of insulin and somatostatin and the accumulation of cyclic AMP in vitro in the rat. Acta endocrinologica. vol 99. issue 3. 1982-06-21. PMID:6122321.' |
in the presence of 6.7 mmol/l of glucose, 3.0 and 30 nmol/l of gip induced both insulin and [3h]cyclic amp responses, while lower and higher concentrations of the peptide were ineffective. |
1982-06-21 |
2023-08-12 |
rat |
| b' J Szec\\xc3\\xb3wka, V Grill, E Sandberg, S Efendi\\xc4\\x8. Effect of GIP on the secretion of insulin and somatostatin and the accumulation of cyclic AMP in vitro in the rat. Acta endocrinologica. vol 99. issue 3. 1982-06-21. PMID:6122321.' |
thus while 30 nmol/l of gip was stimulatory together with 6.7, 16.7 or 33.3 mmol/l of glucose, the peptide stimulated neither insulin release, nor the accumulation of [3h]cyclic amp in the presence of a low concentration of glucose (3.3 mmol/l). |
1982-06-21 |
2023-08-12 |
rat |
| b' J Szec\\xc3\\xb3wka, V Grill, E Sandberg, S Efendi\\xc4\\x8. Effect of GIP on the secretion of insulin and somatostatin and the accumulation of cyclic AMP in vitro in the rat. Acta endocrinologica. vol 99. issue 3. 1982-06-21. PMID:6122321.' |
in this preparation 1.0 to 10 nmol/l of gip stimulated insulin and somatostatin secretion; however while these concentrations were equipotent on insulin release, 10 nmol/l of gip stimulated somatostatin release more than 1 nmol/l, indicating differences in dose-response curves for the gip-induced stimulation of the two hormones. |
1982-06-21 |
2023-08-12 |
rat |
| B Beck, C Villaume, G Debr. Clinical aspects of GIP secretion. Acta diabetologica latina. vol 19. issue 1. 1982-06-14. PMID:6280423. |
the impaired absorption of the food-stuffs and the defective feed-back regulation of gip secretion by insulin are the major causes of these variations. |
1982-06-14 |
2023-08-12 |
Not clear |
| J Takemura, Y Seino, T Yamamura, K Tsuda, S Seino, N Itoh, H Imur. The role of endogenous gastric inhibitory polypeptide in the enteroinsular axis. The Journal of clinical endocrinology and metabolism. vol 54. issue 5. 1982-05-27. PMID:7037822. |
in order to elucidate the relationship between the release of gastric inhibitory polypeptide (gip) and insulin, we compared plasma gip and insulin concentration responses to meal ingestion in normal subjects and patients with various surgical modifications of the food pathway. |
1982-05-27 |
2023-08-12 |
human |
| J Takemura, Y Seino, T Yamamura, K Tsuda, S Seino, N Itoh, H Imur. The role of endogenous gastric inhibitory polypeptide in the enteroinsular axis. The Journal of clinical endocrinology and metabolism. vol 54. issue 5. 1982-05-27. PMID:7037822. |
since the insulin response was enhanced only when both the glucose and gip responses were magnified, we conclude that endogenous gip is a glucose-dependent insulinotropic factor. |
1982-05-27 |
2023-08-12 |
human |
| b' J Szec\\xc3\\xb3wka, P E Lins, S Efendi\\xc4\\x8. Effects of cholecystokinin, gastric inhibitory polypeptide, and secretin on insulin and glucagon secretion in rats. Endocrinology. vol 110. issue 4. 1982-05-21. PMID:7037370.' |
in the basal state, cck-33 and gip produced significant hypoglycemia at all concentrations used, although they elevated insulin levels only at the highest dose. |
1982-05-21 |
2023-08-12 |
rat |
| b' J Szec\\xc3\\xb3wka, P E Lins, S Efendi\\xc4\\x8. Effects of cholecystokinin, gastric inhibitory polypeptide, and secretin on insulin and glucagon secretion in rats. Endocrinology. vol 110. issue 4. 1982-05-21. PMID:7037370.' |
higher doses of gip significantly potentiated insulin release stimulated by glucose or arginine. |
1982-05-21 |
2023-08-12 |
rat |
| D L Sarson, S M Wood, D Holder, S R Bloo. The effect of glucose-dependent insulinotropic polypeptide infused at physiological concentrations on the release of insulin in man. Diabetologia. vol 22. issue 1. 1982-05-21. PMID:7037506. |
blood glucose and the responses of insulin and glucose-dependent insulinotropic polypeptide (gip) were measured in 12 healthy, normal weight subjects after drinking 50 g glucose. |
1982-05-21 |
2023-08-12 |
human |
| D L Sarson, S M Wood, D Holder, S R Bloo. The effect of glucose-dependent insulinotropic polypeptide infused at physiological concentrations on the release of insulin in man. Diabetologia. vol 22. issue 1. 1982-05-21. PMID:7037506. |
the insulin response to oral glucose was, however, far higher (431.3 +/- 58.2 pmol/l) than that obtained after gip and glucose infusion (191.6 +/- 30.9 pmol/l, p less than 0.001). |
1982-05-21 |
2023-08-12 |
human |
| D L Sarson, S M Wood, D Holder, S R Bloo. The effect of glucose-dependent insulinotropic polypeptide infused at physiological concentrations on the release of insulin in man. Diabetologia. vol 22. issue 1. 1982-05-21. PMID:7037506. |
thus it has not proved possible to explain completely the oral enhancement of insulin release by the action of gip alone. |
1982-05-21 |
2023-08-12 |
human |
| P J Hornnes, C Kühl, K B Lauritse. Gastro-entero-pancreatic hormones in normal pregnancy: response to a protein rich meal. European journal of clinical investigation. vol 11. issue 5. 1982-05-12. PMID:6800804. |
the plasma concentrations of gastrin, gastric inhibitory polypeptide (gip), gut glucagon-like-immunoreactivity (gut gli), insulin, glucagon, and pancreatic polypeptide (pp) were studied following the ingestion of a protein rich meal in late pregnancy and postpartum in 11 normal women. |
1982-05-12 |
2023-08-12 |
Not clear |
| P J Hornnes, C Kühl, K B Lauritse. Gastro-entero-pancreatic hormones in normal pregnancy: response to a protein rich meal. European journal of clinical investigation. vol 11. issue 5. 1982-05-12. PMID:6800804. |
in pregnancy, the fasting plasma concentrations of glucose (mean +/- sem in pregnancy: 4.1 +/- 0.1 mmol l-1, postpartum: 4.7 +/- 0.1 mmol l-1, p less than 0.01), gut gli (25 +/- 3 v. 33 +/- 2 pmol-eqv l-1, p less than 0.01), and pp (7.9 +/- 1.0 v. 13.0 +/- 1.2 pmol l-1, p less than 0.01) were decreased, gastrin and gip unaltered, and insulin (90 +/- 9 v. 72 +/- 5 pmol l-1, p less than 0.05) and glucagon (17 +/- 1 v. 13 +/- 1 pmol l-1, p less than 0.01) increased. |
1982-05-12 |
2023-08-12 |
Not clear |
| P J Hornnes, C Kühl, K B Lauritse. Gastro-entero-pancreatic hormones in normal pregnancy: response to a protein rich meal. European journal of clinical investigation. vol 11. issue 5. 1982-05-12. PMID:6800804. |
the gastrin, gip and glucagon responses to the meal were unaffected by pregnancy, whereas the responses of gut gli (integrated responses in pregnancy: 1217 +/- 325 pmol-eqv l-1, postpartum 2223 +/- 404 pmol-eqv l-1, p less than 0.05) and pp (9801 +/- 1440 v. 14,078 +/- 1543 pmol l-1, p less than 0.01) were impaired and the insulin response enhanced (27,973 +/- 6814 v. 11,409 +/- 3102 pmol l-1, p less than 0.01) in pregnancy. |
1982-05-12 |
2023-08-12 |
Not clear |