| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Takemura, Y Seino, T Yamamura, K Yoshiya, Y Ishikawa, N Itoh, H Imur. The evidence for the regulatory role of endogenous GIP as a glucose dependent insulinotropic hormone in patients with duodenal ulcer. Clinical endocrinology. vol 19. issue 3. 1983-12-17. PMID:6354520. |
the degree of exaggerated plasma gip and insulin secretions was more prominent and earlier in totally gastrectomized patients than in duodenal ulcer patients, and was positively correlated with the blood glucose increase during glucose ingestion. |
1983-12-17 |
2023-08-12 |
human |
| W Creutzfeldt, R Ebert, M Nauck, F Stöckman. Disturbances of the entero-insular axis. Scandinavian journal of gastroenterology. Supplement. vol 82. 1983-12-17. PMID:6356314. |
in type ii diabetes hyper- and hyposecretion of gip has been found but no correlation between gip and insulin response. |
1983-12-17 |
2023-08-12 |
Not clear |
| K D Buchanan, J I Kerr, C F Johnston, A O Redmond, B G Crai. The diffuse endocrine system in cystic fibrosis. Scandinavian journal of gastroenterology. Supplement. vol 82. 1983-12-17. PMID:6356316. |
the post-prandial responses of insulin and gip can be improved by substituting an elemental meal, suggesting that malabsorption and local intestinal factors could be causative in the deficient responses. |
1983-12-17 |
2023-08-12 |
Not clear |
| M El-Salhy, S Falkmer, K J Kramer, R D Speir. Immunohistochemical investigations of neuropeptides in the brain, corpora cardiaca, and corpora allata of an adult lepidopteran insect, Manduca sexta (L). Cell and tissue research. vol 232. issue 2. 1983-10-21. PMID:6136331. |
the neurosecretory cells found in the brain were immunoreactive with at least one of the following mammalian antisera, namely those raised against the insulin b-chain, somatostatin, glucagon c-terminal, glucagon n-terminal, pancreatic polypeptide (pp), secretin, vasoactive intestinal polypeptide (vip), glucose-dependent insulinotropic peptide (gip), gastrin c-terminus, enkephalin, alpha- and beta-endorphin, substance p, and calcitonin. |
1983-10-21 |
2023-08-12 |
Not clear |
| K C Ellwood, O E Michaelis, J G Hallfrisch, T M O'Dorisio, S Catalan. Blood insulin, glucose, fructose and gastric inhibitory polypeptide levels in carbohydrate-sensitive and normal men given a sucrose or invert sugar tolerance test. The Journal of nutrition. vol 113. issue 9. 1983-10-21. PMID:6350543. |
in a crossover design, subjects were given 2 g/kg body weight of sucrose or invert sugar, and responses of insulin, glucose, fructose and gastric inhibitory polypeptide (gip) were determined. |
1983-10-21 |
2023-08-12 |
human |
| R Ebert, H Unger, W Creutzfeld. Preservation of incretin activity after removal of gastric inhibitory polypeptide (GIP) from rat gut extracts by immunoadsorption. Diabetologia. vol 24. issue 6. 1983-10-08. PMID:6350081. |
the action of watery rat gut extracts on glucose-induced insulin release in anaesthetized rats was examined before and after removal of gip by immunoadsorption. |
1983-10-08 |
2023-08-12 |
rat |
| R Ebert, H Unger, W Creutzfeld. Preservation of incretin activity after removal of gastric inhibitory polypeptide (GIP) from rat gut extracts by immunoadsorption. Diabetologia. vol 24. issue 6. 1983-10-08. PMID:6350081. |
after injection of gip antiserum in sufficient amounts to neutralize the gip activity in the gut extract preparation, the additional insulin release due to the gut extract was reduced by only 30%. |
1983-10-08 |
2023-08-12 |
rat |
| L S Vasilevskaia, L N Dagaeva, O I Podotykina, L F Poriadkov, T V Laktaev. [Participation of the gastrointestinal tract in regulating the processes of insulin liberation by the pancreas]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 69. issue 6. 1983-09-23. PMID:6347730. |
a later elevation of the insulin concentration in the blood is possibly connected with absorption of aminoacids and some other nutrients and/or liberation of gip in the small intestine. |
1983-09-23 |
2023-08-12 |
Not clear |
| E L Mazzaferri, L Ciofalo, L A Waters, G H Starich, J C Groshong, L DePalm. Effects of gastric inhibitory polypeptide on leucine- and arginine-stimulated insulin release. The American journal of physiology. vol 245. issue 2. 1983-09-20. PMID:6349379. |
insulin release stimulated by single amino acids, with and without gastric inhibitory polypeptide (gip), was studied in vivo in anesthetized rats and in vitro in collagenase-digested isolated rat pancreatic islets. |
1983-09-20 |
2023-08-12 |
rat |
| E L Mazzaferri, L Ciofalo, L A Waters, G H Starich, J C Groshong, L DePalm. Effects of gastric inhibitory polypeptide on leucine- and arginine-stimulated insulin release. The American journal of physiology. vol 245. issue 2. 1983-09-20. PMID:6349379. |
insulin release in vivo during a 15-min intravenous infusion of leucine (0.97 mm) or arginine (0.97 mm) with gip (17 ng/min) was greater than with infusion of either amino acid or gip alone. |
1983-09-20 |
2023-08-12 |
rat |
| E L Mazzaferri, L Ciofalo, L A Waters, G H Starich, J C Groshong, L DePalm. Effects of gastric inhibitory polypeptide on leucine- and arginine-stimulated insulin release. The American journal of physiology. vol 245. issue 2. 1983-09-20. PMID:6349379. |
in contrast, insulin release did not occur with valine infused alone or with gip. |
1983-09-20 |
2023-08-12 |
rat |
| E L Mazzaferri, L Ciofalo, L A Waters, G H Starich, J C Groshong, L DePalm. Effects of gastric inhibitory polypeptide on leucine- and arginine-stimulated insulin release. The American journal of physiology. vol 245. issue 2. 1983-09-20. PMID:6349379. |
insulin release in vitro by isolated islets was greater during a 45-min incubation period with leucine (5-20 mm) or arginine (20 mm) plus gip (10 ng to 10 micrograms/ml) than with either amino acid alone. |
1983-09-20 |
2023-08-12 |
rat |
| E L Mazzaferri, L Ciofalo, L A Waters, G H Starich, J C Groshong, L DePalm. Effects of gastric inhibitory polypeptide on leucine- and arginine-stimulated insulin release. The American journal of physiology. vol 245. issue 2. 1983-09-20. PMID:6349379. |
in vitro insulin release during paired perfusion studies of isolated islets was greater with leucine (20 mm) plus gip (50 ng/min) than with leucine alone, and augmentation of insulin release by gip was demonstrable in both the early and late phases of insulin release. |
1983-09-20 |
2023-08-12 |
rat |
| E L Mazzaferri, L Ciofalo, L A Waters, G H Starich, J C Groshong, L DePalm. Effects of gastric inhibitory polypeptide on leucine- and arginine-stimulated insulin release. The American journal of physiology. vol 245. issue 2. 1983-09-20. PMID:6349379. |
from these results it is concluded that insulin release is greater, both in vivo and in vitro, after leucine or arginine plus gip than with either amino acid or gip alone. |
1983-09-20 |
2023-08-12 |
rat |
| S M Hampton, P Kwasowski, K Tan, L M Morgan, V Mark. Effect of pretreatment with a high fat diet on the gastric inhibitory polypeptide and insulin responses to oral triolein and glucose in rats. Diabetologia. vol 24. issue 4. 1983-08-11. PMID:6345248. |
inhibition of fat-stimulated gip release by exogenous insulin was demonstrated in the untreated control group (plasma gip: 663 +/- 49 versus 853 +/- 92 ng/l, mean +/- sem p less than 0.025), but pretreatment with an oral fat load abolished this effect (plasma gip: 1008 +/- 95 versus 1116 +/- 100 ng/l, p ns). |
1983-08-11 |
2023-08-12 |
rat |
| S M Hampton, P Kwasowski, K Tan, L M Morgan, V Mark. Effect of pretreatment with a high fat diet on the gastric inhibitory polypeptide and insulin responses to oral triolein and glucose in rats. Diabetologia. vol 24. issue 4. 1983-08-11. PMID:6345248. |
pretreatment of rats on a high fat diet causes (1) increased gip secretion in response to an oral fat load, (2) abolition of the feed-back inhibition of exogenous insulin on fat-stimulated gip release, and (3) some degree of insulin resistance. |
1983-08-11 |
2023-08-12 |
rat |
| J Cassar, M A Ghatei, D L Sarson, G F Joplin, K Mashiter, S R Bloo. Enteroglucagon and GIP after oral glucose in patients with prolactinoma and acromegaly. Clinical endocrinology. vol 18. issue 1. 1983-07-08. PMID:6342859. |
we have performed oral glucose tolerance tests (ogtt) in nine patients with prolactinomas, eight patients with active acromegaly, five patients with acromegaly in remission and nine normal controls, and measured blood glucose, plasma insulin, pancreatic glucagon, enteroglucagon, gastric inhibitory polypeptide (gip) and gh during the test. |
1983-07-08 |
2023-08-12 |
Not clear |
| O Oektedalen, P K Opstad, R Jord. Increased plasma response of gastric inhibitory polypeptide to oral glucose and a liquid meal after prolonged starvation in healthy man. Digestion. vol 26. issue 3. 1983-07-08. PMID:6343163. |
the study shows that there is a dietary modulation of the gip response to nutrient stimulation in healthy man and that the augmented gip release is not attributable to insulin release. |
1983-07-08 |
2023-08-12 |
human |
| C Nakanome, H Akai, M Umezu, T Toyota, Y Got. Gastric inhibitory polypeptide (GIP) response to an oral glucose load in the patients with diabetes mellitus. The Tohoku journal of experimental medicine. vol 139. issue 3. 1983-07-08. PMID:6344327. |
diabetics showed significantly higher levels of plasma gip in association with delayed and diminished peak increases in plasma insulin levels. |
1983-07-08 |
2023-08-12 |
human |
| C Nakanome, H Akai, M Umezu, T Toyota, Y Got. Gastric inhibitory polypeptide (GIP) response to an oral glucose load in the patients with diabetes mellitus. The Tohoku journal of experimental medicine. vol 139. issue 3. 1983-07-08. PMID:6344327. |
this exaggerated gip response to an oral glucose load in proportion to the glucose intolerance indicates a relative failure of the beta cell response to gip in diabetics and that the mechanism involved in hypersecretion of gip would be diminution of the inhibition of gip release caused by insulin in diabetics. |
1983-07-08 |
2023-08-12 |
human |