| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Krarup, S Madsbad, A J Moody, L Regeur, O K Faber, J J Holst, L Sestof. Diminished immunoreactive gastric inhibitory polypeptide response to a meal in newly diagnosed type I (insulin-dependent) diabetics. The Journal of clinical endocrinology and metabolism. vol 56. issue 6. 1983-06-23. PMID:6341393. |
as gip is known to potentiate glucose-induced insulin secretion and possibly the biosynthesis of insulin, the low ir-gip responses in subjects with type i diabetes may significantly influence insulin levels and hyperglycemia. |
1983-06-23 |
2023-08-12 |
human |
| J L Botha, A I Vinik, P T Chil. Gastric inhibitory polypeptide in acquired pancreatic diabetes: effects of insulin treatment. The Journal of clinical endocrinology and metabolism. vol 47. issue 3. 1983-06-17. PMID:400725. |
basal levels of gastric inhibitory polypeptide (gip), glucagon-like immunoreactivity, and immunoreactive glucagon levels rose on insulin withdrawal, more so in patients on short-acting insulin, and were lowered by insulin treatment. |
1983-06-17 |
2023-08-11 |
Not clear |
| J L Botha, A I Vinik, P T Chil. Gastric inhibitory polypeptide in acquired pancreatic diabetes: effects of insulin treatment. The Journal of clinical endocrinology and metabolism. vol 47. issue 3. 1983-06-17. PMID:400725. |
insulin treatment did not affect the gip, glucagon-like immunoreactivity, or irg responses to oral glucose. |
1983-06-17 |
2023-08-11 |
Not clear |
| J L Botha, A I Vinik, P T Chil. Gastric inhibitory polypeptide in acquired pancreatic diabetes: effects of insulin treatment. The Journal of clinical endocrinology and metabolism. vol 47. issue 3. 1983-06-17. PMID:400725. |
improved glucose tolerance was greater in patients receiving soluble insulin than in those receiving lente insulin, and there was a significant positive linear correlation between basal plasma gip and blood glucose levels in these patients. |
1983-06-17 |
2023-08-11 |
Not clear |
| S Cataland, T M O'Dorisio, S E Crockett, H S Mekhjia. Gastric inhibitory polypeptide (GIP) and insulin release in duodenal ulcer patients. The Journal of clinical endocrinology and metabolism. vol 47. issue 3. 1983-06-17. PMID:400727. |
gastric inhibitory polypeptide (gip) and insulin release in duodenal ulcer patients. |
1983-06-17 |
2023-08-11 |
human |
| S Cataland, T M O'Dorisio, S E Crockett, H S Mekhjia. Gastric inhibitory polypeptide (GIP) and insulin release in duodenal ulcer patients. The Journal of clinical endocrinology and metabolism. vol 47. issue 3. 1983-06-17. PMID:400727. |
to investigate the role of gastric inhibitory polypeptide (gip) in the hypersecretion of glucose-stimulated insulin release in duodenal ulcer disease, serum glucose, insulin, and immunoreactive gip (ir-gip) were measured in 18 healthy subjects and 10 duodenal ulcer patients after glucose ingestion. |
1983-06-17 |
2023-08-11 |
human |
| L J Miller, J R Malagelada, V L G. Intestinal nutrient influence on the enteroinsular axis. The Journal of clinical endocrinology and metabolism. vol 47. issue 5. 1983-06-17. PMID:400736. |
to learn the contributions to the enteroinsular axis from different levels of the gastrointestinal tract and different nutrients in chyme, we determined serum concentrations of glucose, gastric inhibitory peptide (gip), insulin, and glucagon postprandially in six normal subjects who underwent diversion of chyme just proximal to an occlusive balloon at the ligament of treitz and jejunal infusion of saline or chyme carbohydrate, protein, and lipid, separately or in combination. |
1983-06-17 |
2023-08-11 |
human |
| L J Miller, J R Malagelada, V L G. Intestinal nutrient influence on the enteroinsular axis. The Journal of clinical endocrinology and metabolism. vol 47. issue 5. 1983-06-17. PMID:400736. |
postprandial elevations of serum glucose, gip, and insulin and decrease of serum glucagon were elicited predominantly from the bowel and its contents distal to the ligament of treitz. |
1983-06-17 |
2023-08-11 |
human |
| L J Miller, J R Malagelada, V L G. Intestinal nutrient influence on the enteroinsular axis. The Journal of clinical endocrinology and metabolism. vol 47. issue 5. 1983-06-17. PMID:400736. |
the gastroduodenal segment, although containing several proposed insulinotropic hormones (gastrin, secretin, and cholecystokinin), had no effect on serum glucose of glucagon and stimulated only small insulin and gip responses. |
1983-06-17 |
2023-08-11 |
human |
| P R Flatt, C J Bailey, P Kwasowski, S K Swanston-Flatt, V Mark. Abnormalities of GIP in spontaneous syndromes of obesity and diabetes in mice. Diabetes. vol 32. issue 5. 1983-06-10. PMID:6341126. |
since glucose stimulation of insulin release is defective in both mutant strains, the results strongly implicate pathologically raised gip concentrations in the hyperinsulinemia and related metabolic abnormalities of the obesity-diabetes syndromes. |
1983-06-10 |
2023-08-12 |
mouse |
| P R Flatt, C J Bailey, P Kwasowski, S K Swanston-Flatt, V Mark. Abnormalities of GIP in spontaneous syndromes of obesity and diabetes in mice. Diabetes. vol 32. issue 5. 1983-06-10. PMID:6341126. |
it is suggested that hypersecretion of gip results in part from loss of normal feedback inhibition by endogenous insulin. |
1983-06-10 |
2023-08-12 |
mouse |
| A Ohneda, T Kobayashi, J Nihe. Response of gastric inhibitory polypeptide (GIP) to oral administration of nutrients in normal and pancreatectomized dogs. Regulatory peptides. vol 5. issue 3. 1983-06-10. PMID:6342065. |
in addition, the findings observed in the present study do not support the existence of feedback effect of insulin on gip secretion. |
1983-06-10 |
2023-08-12 |
Not clear |
| H R Berthoud, E R Trimble, A J Mood. Lack of gastric inhibitory polypeptide (GIP) response to vagal stimulation in the rat. Peptides. vol 3. issue 6. 1983-05-27. PMID:6762536. |
in contrast to gip, plasma insulin concentrations showed a rapid and phasic response during sham feeding in the absence of changes of glycemia. |
1983-05-27 |
2023-08-12 |
rat |
| H R Berthoud, E R Trimble, A J Mood. Lack of gastric inhibitory polypeptide (GIP) response to vagal stimulation in the rat. Peptides. vol 3. issue 6. 1983-05-27. PMID:6762536. |
in anesthetized rats electrical stimulation of the vagus nerve was without any effect on plasma gip concentration, while plasma insulin increased rapidly by as much as 150 percent. |
1983-05-27 |
2023-08-12 |
rat |
| R G Oganov, N A Sysoev. [Effect of a glucose-insulin-potassium mixture on the size and clinical course of myocardial infarct]. Kardiologiia. vol 23. issue 1. 1983-05-05. PMID:6339781. |
in order to limit the spread of myocardial infarction, 56 patients with acute myocardial infarction, admitted to hospital within 10 hours after the attack, for two days received continuous intravenous drip infusion of glucose-insulin-potassium mixture (gip) containing: 300 ml glucose, 50 u common insulin, 60 meqv potassium chloride per 1 1 of the solution, at the rate of 1 ml/kg/hour. |
1983-05-05 |
2023-08-12 |
Not clear |
| R A Pederson, A M Buchan, S Zahedi-Asl, C B Chan, J C Brow. Effect of jejunoileal bypass in the rat on the enteroinsular axis. Regulatory peptides. vol 5. issue 1. 1983-05-05. PMID:6762622. |
glucose, insulin and gip responses to oral glucose were compared in jib and control rats. |
1983-05-05 |
2023-08-12 |
rat |
| R A Pederson, A M Buchan, S Zahedi-Asl, C B Chan, J C Brow. Effect of jejunoileal bypass in the rat on the enteroinsular axis. Regulatory peptides. vol 5. issue 1. 1983-05-05. PMID:6762622. |
the effect of glucose and gip on insulin release from the isolated perfused pancreas of the same animals was investigated to determine if jib altered the sensitivity of the beta cell. |
1983-05-05 |
2023-08-12 |
rat |
| R A Pederson, A M Buchan, S Zahedi-Asl, C B Chan, J C Brow. Effect of jejunoileal bypass in the rat on the enteroinsular axis. Regulatory peptides. vol 5. issue 1. 1983-05-05. PMID:6762622. |
glucose, insulin and gip responses to a glucose load were blunted after jib, although basal gip levels were elevated in these animals. |
1983-05-05 |
2023-08-12 |
rat |
| R A Pederson, A M Buchan, S Zahedi-Asl, C B Chan, J C Brow. Effect of jejunoileal bypass in the rat on the enteroinsular axis. Regulatory peptides. vol 5. issue 1. 1983-05-05. PMID:6762622. |
the insulin response of the perfused jib pancreas to gip was 70% reduced from controls although the insulin response to glucose appeared normal. |
1983-05-05 |
2023-08-12 |
rat |
| R A Pederson, A M Buchan, S Zahedi-Asl, C B Chan, J C Brow. Effect of jejunoileal bypass in the rat on the enteroinsular axis. Regulatory peptides. vol 5. issue 1. 1983-05-05. PMID:6762622. |
this study confirms the findings of others that a relationship exists between reduced gip and insulin response to oral glucose after jib, and indicates that a decrease in sensitivity of the beta cell to gip occurs following jib that is not rapidly reversible. |
1983-05-05 |
2023-08-12 |
rat |