| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juris J Meier, Michael A Nauck, Daniel Kranz, Jens J Holst, Carolyn F Deacon, Dirk Gaeckler, Wolfgang E Schmidt, Baptist Gallwit. Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects. Diabetes. vol 53. issue 3. 2004-06-08. PMID:14988249. |
venous blood samples were drawn for the determination of glucose (glucose oxidase), insulin, c-peptide, glp-1 (total and intact), and gip (total and intact; specific immunoassays). |
2004-06-08 |
2023-08-12 |
human |
| M F McCart. The A54T polymorphism of fatty acid-binding protein 2 may entail a reduction in fat-stimulated secretion of GIP that potentiates the adverse impact of fatty diets on insulin sensitivity. Medical hypotheses. vol 61. issue 4. 2004-06-02. PMID:13679012. |
the a54t polymorphism of fatty acid-binding protein 2 may entail a reduction in fat-stimulated secretion of gip that potentiates the adverse impact of fatty diets on insulin sensitivity. |
2004-06-02 |
2023-08-12 |
human |
| M F McCart. The A54T polymorphism of fatty acid-binding protein 2 may entail a reduction in fat-stimulated secretion of GIP that potentiates the adverse impact of fatty diets on insulin sensitivity. Medical hypotheses. vol 61. issue 4. 2004-06-02. PMID:13679012. |
if this thesis proves to be correct, it will help to clarify the importance of appropriate gip secretion to maintenance of insulin sensitivity in the context of fatty diets. |
2004-06-02 |
2023-08-12 |
human |
| Juris J Meier, Oliver Goetze, Jens Anstipp, Dirk Hagemann, Jens J Holst, Wolfgang E Schmidt, Baptist Gallwitz, Michael A Nauc. Gastric inhibitory polypeptide does not inhibit gastric emptying in humans. American journal of physiology. Endocrinology and metabolism. vol 286. issue 4. 2004-04-15. PMID:14678954. |
venous blood was drawn in 30-min intervals for the determination of glucose, insulin, c-peptide, and gip (total and intact). |
2004-04-15 |
2023-08-12 |
human |
| Juris J Meier, Oliver Goetze, Jens Anstipp, Dirk Hagemann, Jens J Holst, Wolfgang E Schmidt, Baptist Gallwitz, Michael A Nauc. Gastric inhibitory polypeptide does not inhibit gastric emptying in humans. American journal of physiology. Endocrinology and metabolism. vol 286. issue 4. 2004-04-15. PMID:14678954. |
there were no differences in glucose, insulin, and c-peptide between the experiments with the infusion of gip or placebo. |
2004-04-15 |
2023-08-12 |
human |
| Torsten P Vahl, David A D'Alessi. Gut peptides in the treatment of diabetes mellitus. Expert opinion on investigational drugs. vol 13. issue 3. 2004-04-13. PMID:15013938. |
since they are potent insulin secretagogues, gip and glp-1 have received considerable attention as potential diabetes therapeutics. |
2004-04-13 |
2023-08-12 |
Not clear |
| Tina Vilsbøll, Thure Krarup, Sten Madsbad, Jens J Hols. Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects. Regulatory peptides. vol 114. issue 2-3. 2004-04-07. PMID:12832099. |
glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are both incretin hormones regulating postprandial insulin secretion. |
2004-04-07 |
2023-08-12 |
human |
| Tina Vilsbøll, Thure Krarup, Sten Madsbad, Jens J Hols. Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects. Regulatory peptides. vol 114. issue 2-3. 2004-04-07. PMID:12832099. |
insulin concentrations at the end of the three infusion periods (60, 150 and 240 min) during the gip clamp amounted to 53+/-5, 79+/-8 and 113+/-15 pmol/l, respectively. |
2004-04-07 |
2023-08-12 |
human |
| Simon A Hinke, Susanne Manhart, Kerstin Kühn-Wache, Cuilan Nian, Hans-Ulrich Demuth, Raymond A Pederson, Christopher H S McIntos. [Ser2]- and [SerP2] incretin analogs: comparison of dipeptidyl peptidase IV resistance and biological activities in vitro and in vivo. The Journal of biological chemistry. vol 279. issue 6. 2004-04-01. PMID:14610075. |
glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip; also known as gastric inhibitory polypeptide) are incretin hormones that reduce postprandial glycemic excursions via enhancing insulin release but are rapidly inactivated by enzymatic n-terminal truncation. |
2004-04-01 |
2023-08-12 |
rat |
| Frédéric Preitner, Mark Ibberson, Isobel Franklin, Christophe Binnert, Mario Pende, Asllan Gjinovci, Tanya Hansotia, Daniel J Drucker, Claes Wollheim, Rémy Burcelin, Bernard Thoren. Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors. The Journal of clinical investigation. vol 113. issue 4. 2004-03-26. PMID:14966573. |
gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking glp-1 and gip receptors. |
2004-03-26 |
2023-08-12 |
mouse |
| Ronald H Clements, Quintin H Gonzalez, Calvin I Long, Gary Wittert, Henry L Law. Hormonal changes after Roux-en Y gastric bypass for morbid obesity and the control of type-II diabetes mellitus. The American surgeon. vol 70. issue 1. 2004-03-12. PMID:14964537. |
preoperatively, 20 mo patients with dm-ii were evaluated for demographics and fasting levels of the following: glucose, insulin, c-peptide, glucagon, cortisol, gastric inhibitory polypeptide (gip), and glucagon-like peptide-1 (glp-1). |
2004-03-12 |
2023-08-12 |
Not clear |
| S Bakhøj, A Flint, J J Holst, I Teten. Lower glucose-dependent insulinotropic polypeptide (GIP) response but similar glucagon-like peptide 1 (GLP-1), glycaemic, and insulinaemic response to ancient wheat compared to modern wheat depends on processing. European journal of clinical nutrition. vol 57. issue 10. 2004-03-08. PMID:14506486. |
to test the hypothesis that bread made from the ancient wheat einkorn (triticum monococcum) reduces the insulin and glucose responses through modulation of the gastrointestinal responses of glucose-dependent insulinotrophic polypeptide (gip) and glucagon-like peptide 1 (glp-1) compared to the responses to bread of modern wheat (triticum aestivum). |
2004-03-08 |
2023-08-12 |
Not clear |
| Juris J Meier, Baptist Gallwitz, Nina Siepmann, Jens J Holst, Carolyn F Deacon, Wolfgang E Schmidt, Michael A Nauc. The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP). Regulatory peptides. vol 113. issue 1-3. 2004-02-26. PMID:12686467. |
the reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (gip). |
2004-02-26 |
2023-08-12 |
human |
| Juris J Meier, Baptist Gallwitz, Nina Siepmann, Jens J Holst, Carolyn F Deacon, Wolfgang E Schmidt, Michael A Nauc. The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP). Regulatory peptides. vol 113. issue 1-3. 2004-02-26. PMID:12686467. |
since the c-peptide/insulin ratio is reduced after oral glucose ingestion, the incretin hormone gastric inhibitory polypeptide (gip) has been assumed to decrease hepatic insulin extraction. |
2004-02-26 |
2023-08-12 |
human |
| Juris J Meier, Baptist Gallwitz, Nina Siepmann, Jens J Holst, Carolyn F Deacon, Wolfgang E Schmidt, Michael A Nauc. The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP). Regulatory peptides. vol 113. issue 1-3. 2004-02-26. PMID:12686467. |
it was the aim of the present study to evaluate the effects of gip on insulin extraction. |
2004-02-26 |
2023-08-12 |
human |
| Juris J Meier, Baptist Gallwitz, Nina Siepmann, Jens J Holst, Carolyn F Deacon, Wolfgang E Schmidt, Michael A Nauc. The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP). Regulatory peptides. vol 113. issue 1-3. 2004-02-26. PMID:12686467. |
an intravenous injection of 20 pmol gip/kg body weight, with capillary and venous blood samples collected over 30 min for insulin, c-peptide and gip (specific immunoassays). |
2004-02-26 |
2023-08-12 |
human |
| Juris J Meier, Baptist Gallwitz, Nina Siepmann, Jens J Holst, Carolyn F Deacon, Wolfgang E Schmidt, Michael A Nauc. The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP). Regulatory peptides. vol 113. issue 1-3. 2004-02-26. PMID:12686467. |
the rise in insulin after oral glucose and after intravenous gip administration significantly exceeded the rise in c-peptide (p<0.0001). |
2004-02-26 |
2023-08-12 |
human |
| Juris J Meier, Baptist Gallwitz, Nina Siepmann, Jens J Holst, Carolyn F Deacon, Wolfgang E Schmidt, Michael A Nauc. The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP). Regulatory peptides. vol 113. issue 1-3. 2004-02-26. PMID:12686467. |
estimating insulin extraction from the total integrated insulin and c-peptide concentrations (aucs), only the oral glucose load (p<0.0001), but not the intravenous gip administration (p=0.18) significantly reduced insulin clearance. |
2004-02-26 |
2023-08-12 |
human |
| Lisa I Jepeal, Michael O Boylan, M Michael Wolf. Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene functions through a GATA and an ISL-1 motif in a mouse neuroendocrine tumor cell line. Regulatory peptides. vol 113. issue 1-3. 2004-02-26. PMID:12686473. |
glucose-dependent insulinotropic polypeptide (gip) is a 42-amino acid gastrointestinal regulatory peptide that, in the presence of glucose, stimulates insulin secretion from beta-cells. |
2004-02-26 |
2023-08-12 |
mouse |
| Marian Dalgaard, Claus Thomsen, Birthe M Rasmussen, Jens J Holst, Kjeld Hermanse. Ethanol with a mixed meal decreases the incretin levels early postprandially and increases postprandial lipemia in type 2 diabetic patients. Metabolism: clinical and experimental. vol 53. issue 1. 2004-02-18. PMID:14681846. |
the incretins, glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide 1 (glp-1), are important hormones from the gut that enhance nutrient-stimulated insulin secretion. |
2004-02-18 |
2023-08-12 |
human |