Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Zhipeng Tao, Zhiyong Chen. Hormonal regulation of metabolism-recent lessons learned from insulin and estrogen. Clinical science (London, England : 1979). vol 137. issue 6. 2023-03-21. PMID:36942499. |
in addition, we discuss the cross-talk between estrogen signaling and insulin signaling via sirt1, mtor, and pi3k, as well as new therapeutic options such as agonists of glp1 receptor, gip receptor, and β3-ar. |
2023-03-21 |
2023-08-14 |
Not clear |
Saiedeh Erfanian, Hamed Mir, Amir Abdoli, Abazar Roustazade. Association of gastric inhibitory polypeptide receptor (GIPR) gene polymorphism with type 2 diabetes mellitus in iranian patients. BMC medical genomics. vol 16. issue 1. 2023-03-07. PMID:36882778. |
gastric inhibitory polypeptide receptor (gipr) encodes a g-protein coupled receptor for gastric inhibitory polypeptide (gip), which was demonstrated to stimulate insulin secretion. |
2023-03-07 |
2023-08-14 |
Not clear |
Bo Ahré. Contribution of GIP and GLP-1 to the Insulin Response to Oral Administration of Glucose in Female Mice. Biomedicines. vol 11. issue 2. 2023-02-25. PMID:36831127. |
contribution of gip and glp-1 to the insulin response to oral administration of glucose in female mice. |
2023-02-25 |
2023-08-14 |
mouse |
Bo Ahré. Contribution of GIP and GLP-1 to the Insulin Response to Oral Administration of Glucose in Female Mice. Biomedicines. vol 11. issue 2. 2023-02-25. PMID:36831127. |
now, i have proceeded and studied the contribution of glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (glp-1) to the insulin response to oral glucose in female mice by using receptor antagonists. |
2023-02-25 |
2023-08-14 |
mouse |
Jarosław Nuszkiewicz, Jolanta Czuczejko, Wiktor Dróżdż, Alina Woźniak, Bogdan Małkowski, Karolina Szewczyk-Gole. Concentration of Selected Adipokines and Factors Regulating Carbohydrate Metabolism in Patients with Head and Neck Cancer in Respect to Their Body Mass Index. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36834693. |
the aim of the study was to determine the concentrations of ghrelin, omentin-1, adipsin, adiponectin, leptin, resistin, visfatin, glucagon, insulin, c-peptide, glucagon-like peptide-1 (glp-1), plasminogen activator inhibitor-1 (pai-1), and gastric inhibitory peptide (gip) in the blood serum of hnc patients depending on their body mass index (bmi). |
2023-02-25 |
2023-08-14 |
Not clear |
Amy L George, Rachel E Foreman, Mariwan H Sayda, Frank Reimann, Fiona M Gribble, Richard G Ka. Rapid and Quantitative Enrichment of Peptides from Plasma for Mass Spectrometric Analysis. Methods in molecular biology (Clifton, N.J.). vol 2628. 2023-02-13. PMID:36781802. |
peptides studied using this methodology include insulin, c-peptide, glucagon, pyy, gip, and a number of other challenging gut peptide hormones. |
2023-02-13 |
2023-08-14 |
Not clear |
Snehasish Nag, Samanwita Mandal, Tanmay Majumdar, Satinath Mukhopadhyay, Rakesh Kund. FFA-Fetuin-A regulates DPP-IV expression in pancreatic beta cells through TLR4-NFkB pathway. Biochemical and biophysical research communications. vol 647. 2023-01-30. PMID:36716646. |
dipeptidyl peptidase 4 (dpp-iv) is a ubiquitous proteolytic enzyme that cleaves incretin hormones, such as glucagon-like peptide 1 (glp1) and gastric inhibitory protein (gip), leading to reduced glucose stimulated insulin secretion from the pancreatic beta cells. |
2023-01-30 |
2023-08-14 |
mouse |
Eleonora Grespan, Andrea Mar. Does glucose lowering restore GIP effects on insulin secretion? Nutrition, metabolism, and cardiovascular diseases : NMCD. 2023-01-29. PMID:36710118. |
does glucose lowering restore gip effects on insulin secretion? |
2023-01-29 |
2023-08-14 |
Not clear |
Eleonora Grespan, Andrea Mar. Does glucose lowering restore GIP effects on insulin secretion? Nutrition, metabolism, and cardiovascular diseases : NMCD. 2023-01-29. PMID:36710118. |
some studies have shown that in type 2 diabetic patients the potentiation of insulin secretion by glucose-dependent insulinotropic polypeptide (gip) is compromised but can be partially restored if glucose is lowered. |
2023-01-29 |
2023-08-14 |
Not clear |
Reema Abu Khalaf, Ebtisam Alwarafi, Dima Sabba. Piperazine sulfonamides as DPP-IV inhibitors: Synthesis, induced-fit docking and Acta pharmaceutica (Zagreb, Croatia). vol 71. issue 4. 2023-01-18. PMID:36651550. |
dipeptidyl peptidase-iv (dpp-iv) inhibitors minimize glucagon and blood glucose levels by increasing the incretin levels, glucagon-like peptide (glp-1) and glucose-dependent insulinotropic poly-peptide (gip), leading to insulin secretion from pancreatic beta cells. |
2023-01-18 |
2023-08-14 |
Not clear |
Giovanni Targher, Alessandro Mantovani, Christopher D Byrn. Mechanisms and possible hepatoprotective effects of glucagon-like peptide-1 receptor agonists and other incretin receptor agonists in non-alcoholic fatty liver disease. The lancet. Gastroenterology & hepatology. vol 8. issue 2. 2023-01-09. PMID:36620987. |
glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are incretins that stimulate insulin secretion from pancreatic β cells in response to food ingestion. |
2023-01-09 |
2023-08-14 |
Not clear |
Nanna Thurmann Jørgensen, Trine Møller Erichsen, Morten Buus Jørgensen, Thomas Idorn, Bo Feldt-Rasmussen, Jens J Holst, Ulla Feldt-Rasmussen, Marianne Klos. Glucose metabolism, gut-brain hormones, and acromegaly treatment: an explorative single centre descriptive analysis. Pituitary. 2023-01-07. PMID:36609655. |
the objective of the study was to describe the differential effect of various treatment regimens on the secretion of glucose, insulin, glucagon, glucagon-like peptide-1 (glp-1), and glucose-dependent insulinotropic polypeptide (gip) in patients with acromegaly. |
2023-01-07 |
2023-08-14 |
Not clear |
Ioannis G Lempesis, Junli Liu, Maria Dalamag. The Metabolism open. vol 16. 2022-12-19. PMID:36530219. |
glp-1 and gip exert pleiotropic physiological actions, including enhancement of insulin secretion, glycemic and appetite control, cardioprotection, and adipose tissue improved function among others. |
2022-12-19 |
2023-08-14 |
Not clear |
Rola Hammoud, Daniel J Drucke. Beyond the pancreas: contrasting cardiometabolic actions of GIP and GLP1. Nature reviews. Endocrinology. 2022-12-12. PMID:36509857. |
glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide 1 (glp1) exhibit incretin activity, meaning that they potentiate glucose-dependent insulin secretion. |
2022-12-12 |
2023-08-14 |
Not clear |
Imma Forzano, Fahimeh Varzideh, Roberta Avvisato, Stanislovas S Jankauskas, Pasquale Mone, Gaetano Santull. Tirzepatide: A Systematic Update. International journal of molecular sciences. vol 23. issue 23. 2022-12-11. PMID:36498958. |
gip and glp1 are incretin hormones: they are released in the intestine in response to nutrient intake and stimulate pancreatic beta cell activity secreting insulin. |
2022-12-11 |
2023-08-14 |
Not clear |
Aya Yanagimoto, Yuji Matsui, Tohru Yamaguchi, Masanobu Hibi, Shigeru Kobayashi, Noriko Osak. Effects of Ingesting Both Catechins and Chlorogenic Acids on Glucose, Incretin, and Insulin Sensitivity in Healthy Men: A Randomized, Double-Blinded, Placebo-Controlled Crossover Trial. Nutrients. vol 14. issue 23. 2022-12-11. PMID:36501092. |
postprandial glucose, insulin, glucagon-like peptide-1 (glp-1), and glucose-dependent insulinotropic polypeptide (gip) responses were measured at baseline and after treatments. |
2022-12-11 |
2023-08-14 |
human |
Vivesh, Baljit Kaur, Sombir Jaglan, Sudesh Rani, Yatin Batra, Palwinder Sing. Proline Based Rationally Designed Peptide Esters against Dipeptidyl peptidase-4: Highly Potent Anti-Diabetic Agents. Bioorganic & medicinal chemistry letters. 2022-10-09. PMID:36209967. |
since dpp-4 cleaves the glucagon like peptide (glp-1) and glucose dependent insulinotropic polypeptide (gip) hormones which are responsible for inducing insulin secretion, the results of present studies could be significant in making control over glycemia. |
2022-10-09 |
2023-08-14 |
Not clear |
Bashaier Al-Zaid, Siby Chacko, Charles Ifeamalume Ezeamuzie, Moritz Bünemann, Cornelius Krasel, Tina Karimian, Peter Lanzerstorfer, Suleiman Al-Saba. Differential effects of glucose-dependent insulinotropic polypeptide receptor/glucagon-like peptide-1 receptor heteromerization on cell signaling when expressed in HEK-293 cells. Pharmacology research & perspectives. vol 10. issue 5. 2022-09-30. PMID:36177761. |
the incretin hormones: glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (glp-1) are important regulators of many aspects of metabolism including insulin secretion. |
2022-09-30 |
2023-08-14 |
Not clear |
Giuseppe Lisco, Anna De Tullio, Olga Disoteo, Vincenzo De Geronimo, Giuseppina Piazzolla, Giovanni De Pergola, Vito Angelo Giagulli, Emilio Jirillo, Edoardo Guastamacchia, Carlo Sabbà, Vincenzo Triggian. Basal insulin intensification with GLP-1RA and dual GIP and GLP-1RA in patients with uncontrolled type 2 diabetes mellitus: A rapid review of randomized controlled trials and meta-analysis. Frontiers in endocrinology. vol 13. 2022-09-26. PMID:36157450. |
basal insulin intensification with glp-1ra and dual gip and glp-1ra in patients with uncontrolled type 2 diabetes mellitus: a rapid review of randomized controlled trials and meta-analysis. |
2022-09-26 |
2023-08-14 |
Not clear |
Giuseppe Lisco, Anna De Tullio, Olga Disoteo, Vincenzo De Geronimo, Giuseppina Piazzolla, Giovanni De Pergola, Vito Angelo Giagulli, Emilio Jirillo, Edoardo Guastamacchia, Carlo Sabbà, Vincenzo Triggian. Basal insulin intensification with GLP-1RA and dual GIP and GLP-1RA in patients with uncontrolled type 2 diabetes mellitus: A rapid review of randomized controlled trials and meta-analysis. Frontiers in endocrinology. vol 13. 2022-09-26. PMID:36157450. |
herein, we overviewed the role of gip and glp-1 in the pathophysiology of type 2 diabetes and systematically reviewed the efficacy and safety of injectable incretin-based therapy added to basal insulin in light of the results of the surpass-5 trial. |
2022-09-26 |
2023-08-14 |
Not clear |