| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kayoko Kamemoto, Yusei Tataka, Ayano Hiratsu, Chihiro Nagayama, Yuka Hamada, Koji Kurata, Michiko Chiyoda, Machi Ito, Masashi Miyashit. Effect of vegetable consumption with chewing on postprandial glucose metabolism in healthy young men: a randomised controlled study. Scientific reports. vol 14. issue 1. 2024-03-30. PMID:38555375. |
although plasma glucose concentrations did not differ between the trials, the plasma insulin and gip incremental area under the curve values were higher in the chewing than in the non-chewing trial. |
2024-03-30 |
2024-04-02 |
Not clear |
| Christopher Bannon, Claire Meek, Frank Reimann, Fiona M Gribbl. Fasting and Post Prandial Pancreatic and Enteroendocrine Hormone Levels in Obese and Non-Obese Participants. Peptides. 2024-03-15. PMID:38490484. |
participants: with healthy bmi (n=15), overweight bmi (n=29) and obesity (n=161) had samples taken fasting and 30min post mixed liquid meal for analysis of glucagon-like peptide-1 (glp-1), pyy, glucose-dependent insulinotropic polypeptide (gip), insulin and glucagon. |
2024-03-15 |
2024-03-18 |
human |
| Christopher Bannon, Claire Meek, Frank Reimann, Fiona M Gribbl. Fasting and Post Prandial Pancreatic and Enteroendocrine Hormone Levels in Obese and Non-Obese Participants. Peptides. 2024-03-15. PMID:38490484. |
data visualiation used linear discriminant analysis for dimensionality reduction, to visualise the data and assess scaling of each hormone fasting levels of insulin, gip and pyy were shown to be key classifiers between the 3 groups on ancova analysis, with an observation of increased gip levels in overweight, but not obese participants. |
2024-03-15 |
2024-03-18 |
human |
| Christopher Bannon, Claire Meek, Frank Reimann, Fiona M Gribbl. Fasting and Post Prandial Pancreatic and Enteroendocrine Hormone Levels in Obese and Non-Obese Participants. Peptides. 2024-03-15. PMID:38490484. |
in non-obese subjects, fasting gip, pyy and insulin correlated with bmi, whereas in obese people only the pancreatic hormones glucagon and insulin correlated with bmi. |
2024-03-15 |
2024-03-18 |
human |
| Dorte B Zilstorff, Michael M Richter, Jens Hannibal, Henrik L Jørgensen, Henriette P Sennels, Nicolai J Wewer Albrechtse. Secretion of glucagon, GLP-1 and GIP may be affected by circadian rhythm in healthy males. BMC endocrine disorders. vol 24. issue 1. 2024-03-14. PMID:38481208. |
glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are secreted from gut endocrine cells during meals and control glucose homeostasis by potentiating insulin secretion and inhibiting food intake. |
2024-03-14 |
2024-03-16 |
Not clear |
| Angyi Lin, Hideki Kitaura, Fumitoshi Ohori, Takahiro Noguchi, Aseel Marahleh, Jinghan Ma, Jiayi Ren, Mariko Miura, Ziqiu Fan, Kohei Narita, Itaru Mizoguch. (D-Ala International journal of molecular sciences. vol 25. issue 5. 2024-03-13. PMID:38473802. |
(d-ala glucose-insulinotropic polypeptide (gip) is an incretin hormone that induces insulin secretion and decreases blood glucose levels. |
2024-03-13 |
2024-03-15 |
Not clear |
| Kathleen M Sicinski, Damla Sürmeli, Jasper Du, Venkata S Raman, Vittorio Montanari, Minhee Lee, Benjamin N Harwood, Alan S Kopin, Martin Beinborn, Krishna Kuma. A Robust Platform for the Molecular Design of Potent, Protease-Stable, Long-Acting GIP Analogues. Journal of medicinal chemistry. 2024-03-08. PMID:38458970. |
gip binds to its cognate receptor, gipr, and mediates metabolic physiology by improved insulin sensitivity, β-cell proliferation, increased energy consumption, and stimulated glucagon secretion. |
2024-03-08 |
2024-03-11 |
Not clear |
| Samuel Mendoza-Pérez, Itzel Orta-Méndez-Y-Sánchez, Rolando Salvador García-Gómez, Guillermo Ordaz-Nava, María Isabel Gracia-Mora, Lucía Macías-Rosales, Héctor A Rico-Morales, Gerardo Salas-Garrido, María Del Carmen Durán-Domínguez-de-Bazú. Stevia rebaudiana Bertoni, an American plant used as sweetener: Study of its effects on body mass control and glycemia reduction in Wistar male and female rats. PloS one. vol 19. issue 2. 2024-02-27. PMID:38412182. |
euthanasia was done and blood serum was collected to evaluate the following biochemical parameters: glucose, triglycerides, cholesterol, insulin, glucagon, leptin, ghrelin, and glucose-dependent insulinotropic peptide, gip. |
2024-02-27 |
2024-03-01 |
rat |
| Xin Jiang, Ji Li, Xiaohui Yao, Hao Ding, Aihong Gu, Zhen Zho. Neuroprotective effects of dipeptidyl peptidase 4 inhibitor on Alzheimer's disease: a narrative review. Frontiers in pharmacology. vol 15. 2024-02-26. PMID:38405664. |
beyond dpp4i's benefits in alleviating insulin resistance and glucose-lowering, underlying mechanisms for the potential neuroprotection with dpp4i medications were categorized into the following sections: (ferrari et al., physiol rev, 2021, 101, 1,047-1,081): the benefits of dpp4is on directly ameliorating the burden of β-amyloid plaques and reducing the formation of neurofibrillary tangles; dpp4i increasing the bioactivity of neuroprotective dpp4 substrates including glucagon-like peptide-1 (glp-1), glucose-dependent insulinotropic peptide (gip), and stromal-derived factor-1α (sdf-1α) etc. |
2024-02-26 |
2024-02-28 |
Not clear |
| Rolien Bosch, Marcella Petrone, Rosalin Arends, Paolo Vicini, Eric J G Sijbrands, Sven Hoefman, Nelleke Snelde. Characterisation of cotadutide's dual GLP-1/glucagon receptor agonistic effects on glycaemic control using an in vivo human glucose regulation quantitative systems pharmacology model. British journal of pharmacology. 2024-02-25. PMID:38403793. |
we characterised the effects of cotadutide on glucose, insulin, glp-1, gip, and glucagon over time in a quantitative manner using our glucose dynamics systems model (4gi systems model), in combination with clinical data from a multiple ascending dose/phase 2a (mad/ph2a) study in overweight and obese subjects with a history of type 2 diabetes mellitus (nct02548585). |
2024-02-25 |
2024-02-28 |
human |
| Snehasish Nag, Samanwita Mandal, Oindrila Mukherjee, Tanmay Majumdar, Satinath Mukhopadhyay, Rakesh Kund. Vildagliptin inhibits high fat and fetuin-A mediated DPP-4 expression, intracellular lipid accumulation and improves insulin secretory defects in pancreatic beta cells. Biochimica et biophysica acta. Molecular basis of disease. vol 1870. issue 3. 2024-02-03. PMID:38296116. |
dipeptidyl peptidase-4 (dpp-4), a ubiquitous proteolytic enzyme, inhibits insulin secretion from pancreatic beta cells by inactivating circulating incretin hormones glp-1 and gip. |
2024-02-03 |
2024-02-06 |
mouse |
| Marta Santos Hernandez, Frank Reimann, Fiona M Gribbl. Cellular mechanisms of incretin hormone secretion. Journal of molecular endocrinology. 2024-01-19. PMID:38240302. |
the incretin hormones glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are involved in the regulation of insulin secretion, appetite, food intake and body weight after their nutrient-induced secretion from the gut. |
2024-01-19 |
2024-01-21 |
Not clear |
| Landon S Deru, Elizabeth Z Gipson, Katelynn E Hales, Benjamin T Bikman, Lance E Davidson, Benjamin D Horne, James D LeCheminant, Larry A Tucker, Bruce W Baile. The Effects of a High-Carbohydrate versus a High-Fat Shake on Biomarkers of Metabolism and Glycemic Control When Used to Interrupt a 38-h Fast: A Randomized Crossover Study. Nutrients. vol 16. issue 1. 2024-01-11. PMID:38201992. |
this study aimed to determine the impact of various fast-interrupting shakes on markers of glycemic control including glucose, β-hydroxybutyrate (bhb), insulin, glucagon, glp-1, and gip. |
2024-01-11 |
2024-01-13 |
Not clear |
| Vijaya Subramanian, Jonatan I Bagger, Vinayak Harihar, Jens J Holst, Filip K Knop, Tina Vilsbøl. An Extended Minimal Model of OGTT: Estimation of Alpha- and Beta-Cell Dysfunction, Insulin Resistance, and the Incretin Effect. American journal of physiology. Endocrinology and metabolism. 2023-12-13. PMID:38088864. |
the extended model describes glucose and hormone dynamics in ogtt including the contribution of the incretins, glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip), to insulin secretion. |
2023-12-13 |
2023-12-17 |
human |
| Karlijn A C Meeks, Amy R Bentley, Themistocles L Assimes, Nora Franceschini, Adebowale A Adeyemo, Charles N Rotimi, Ayo P Doumate. Mendelian randomization analyses suggest a causal role for circulating GIP and IL-1RA levels in homeostatic model assessment-derived measures of β-cell function and insulin sensitivity in Africans without type 2 diabetes. Genome medicine. vol 15. issue 1. 2023-12-04. PMID:38049854. |
mendelian randomization analyses suggest a causal role for circulating gip and il-1ra levels in homeostatic model assessment-derived measures of β-cell function and insulin sensitivity in africans without type 2 diabetes. |
2023-12-04 |
2023-12-10 |
Not clear |
| Rikke Viggers, Nicklas Højgaard-Hessellund Rasmussen, Peter Vestergaar. Effects of Incretin Therapy on Skeletal Health in Type 2 Diabetes-A Systematic Review. JBMR plus. vol 7. issue 11. 2023-12-01. PMID:38025038. |
the group of hormones known as incretins, which includes gastric inhibitory peptide (gip) and glucagon-like peptide 1 (glp-1), play a role in regulating bowel function and insulin secretion during feeding. |
2023-12-01 |
2023-12-07 |
human |
| Rikke Viggers, Nicklas Højgaard-Hessellund Rasmussen, Peter Vestergaar. Effects of Incretin Therapy on Skeletal Health in Type 2 Diabetes-A Systematic Review. JBMR plus. vol 7. issue 11. 2023-12-01. PMID:38025038. |
the group of hormones known as incretins, which includes gastric inhibitory peptide (gip) and glucagon-like peptide 1 (glp-1), play a role in regulating bowel function and insulin secretion during feeding. |
2023-11-29 |
2023-12-07 |
human |
| Julia Herrou, Guillaume Mabilleau, Jean-Michel Lecerf, Thierry Thomas, Emmanuel Biver, Julien Pacco. Narrative Review of Effects of Glucagon-Like Peptide-1 Receptor Agonists on Bone Health in People Living with Obesity. Calcified tissue international. 2023-11-24. PMID:37999750. |
further studies are needed to investigate the bone impact of glp-1ra, dual- and triple-receptor agonists for glp-1, glucose-dependent insulin releasing polypeptide (gip), and glucagon in pwo. |
2023-11-24 |
2023-11-29 |
Not clear |
| Sara Becerril, Javier A Cienfuegos, Amaia Rodríguez, Victoria Catalán, Beatriz Ramírez, Víctor Valentí, Rafael Moncada, Xabier Unamuno, Javier Gómez-Ambrosi, Gema Frühbec. Single anastomosis duodeno-ileal bypass with sleeve gastrectomy generates sustained improvement of glycemic control compared with sleeve gastrectomy in the diet-induced obese rat model. Journal of physiology and biochemistry. 2023-11-07. PMID:37935948. |
body weight and food intake were weekly monitored, and 6 weeks after interventions, fasting plasma glucose, oral glucose and insulin tolerance tests, plasma insulin, adiponectin, gip, glp-1, and ghrelin levels were determined.the body weight of sadi-s rats was significantly (p < 0.001) lower as compared to the sham-operated, sg, and pair-fed groups. |
2023-11-07 |
2023-11-20 |
rat |
| Bijayashree Sahu, Sunil Pani, Gourabamani Swalsingh, Unmod Senapati, Punyadhara Pani, Benudhara Pati, Subhasmita Rout, Rimjhim Trivedi, Ritu Raj, Suchanda Dey, Amar Jeet, Dinesh Kumar, Naresh C Ba. Long-term physical inactivity induces significant changes in biochemical pathways related to metabolism of proteins and glycerophospholipids in mice. Molecular omics. 2023-11-01. PMID:37909389. |
our data suggest that cytokines linked to glycemic excursions (insulin, c-peptide, glucagon) and their passive regulators (leptin, bdnf, active ghrelin, and gip) exhibit changes in the sed group. |
2023-11-01 |
2023-11-08 |
mouse |