| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Signe Tellerup Nielsen, Nina Majlund Harder-Lauridsen, Fabiana Braga Benatti, Anne-Sophie Wedell-Neergaard, Mark Preben Lyngbæk, Kirsten Møller, Bente Klarlund Pedersen, Rikke Krogh-Madse. The effect of 8 days of strict bed rest on the incretin effect in healthy volunteers. Journal of applied physiology (Bethesda, Md. : 1985). vol 120. issue 6. 2016-12-13. PMID:26679616. |
concentrations of glucose, insulin, c-peptide, and gip measured during the ogtt were higher after the bed rest intervention (all p < 0.05), whereas there was no difference in the levels of glp-1 and glucagon. |
2016-12-13 |
2023-08-13 |
human |
| Tsuyoshi Yanagimachi, Yukihiro Fujita, Yasutaka Takeda, Jun Honjo, Kuralay K Atageldiyeva, Yumi Takiyama, Atsuko Abiko, Yuichi Makino, Timothy J Kieffer, Masakazu Haned. Pancreatic glucose-dependent insulinotropic polypeptide (GIP) (1-30) expression is upregulated in diabetes and PEGylated GIP(1-30) can suppress the progression of low-dose-STZ-induced hyperglycaemia in mice. Diabetologia. vol 59. issue 3. 2016-12-13. PMID:26693710. |
while the predominant form is gip(1-42), a shorter form, gip(1-30), is produced by pancreatic alpha cells and promotes insulin secretion in a paracrine manner. |
2016-12-13 |
2023-08-13 |
mouse |
| T Milewicz, K Migacz, M Kiałka, I Rogatko, A Kowalczuk, M Spalkowska, S Mrozińska, Z Czajkowska, K Sztefk. Basic and Meal Stimulated Plasma GIP Levels are Higher in Lean PCOS Women with FAI over 5. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. vol 124. issue 2. 2016-11-14. PMID:26895276. |
glucose dependent insulinotropic peptide (gip) belongs to the incretins which are responsible for 70% of the insulin release after oral glucose intake. |
2016-11-14 |
2023-08-13 |
Not clear |
| Eun Ky Kim, Tae Jung Oh, Lee-Kyung Kim, Young Min Ch. Improving Effect of the Acute Administration of Dietary Fiber-Enriched Cereals on Blood Glucose Levels and Gut Hormone Secretion. Journal of Korean medical science. vol 31. issue 2. 2016-10-28. PMID:26839476. |
on day 2, the levels of plasma glucose, glp-1, glucose-dependent insulinotropic polypeptide (gip), and insulin were measured. |
2016-10-28 |
2023-08-13 |
human |
| Eun Ky Kim, Tae Jung Oh, Lee-Kyung Kim, Young Min Ch. Improving Effect of the Acute Administration of Dietary Fiber-Enriched Cereals on Blood Glucose Levels and Gut Hormone Secretion. Journal of Korean medical science. vol 31. issue 2. 2016-10-28. PMID:26839476. |
however, there were no differences in the plasma insulin, glucagon, glp-1, and gip levels. |
2016-10-28 |
2023-08-13 |
human |
| J Hukkanen, J Rysa, K A Makela, K-H Herzig, J Hakkola, M J Savolaine. The effect of pregnane X receptor agonists on postprandial incretin hormone secretion in rats and humans. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 66. issue 6. 2016-10-24. PMID:26769831. |
rifampicin treatment did not affect glucose, insulin, glp-1, gip, glucagon, and peptide yy levels statistically significantly. |
2016-10-24 |
2023-08-13 |
human |
| Roger Reidelberger, Alvin Haver, Krista Anders, Bettye Apenteng, Craig Lani. Effects of solid-phase extraction of plasma in measuring gut metabolic hormones in fasted and fed blood of lean and diet-induced obese rats. Physiological reports. vol 4. issue 10. 2016-10-13. PMID:27207785. |
individual enzyme-linked immunoassays and a multiplex assay were used to measure active glp-1, total pyy, active amylin, active ghrelin, insulin, leptin, and total gip in response to (1) addition of known amounts of the peptides to lean and obese plasma, (2) a large meal in lean and obese rats, and (3) intravenous infusions of anorexigenic doses of glp-1, pyy(3-36), amylin, and leptin in lean rats. |
2016-10-13 |
2023-08-13 |
rat |
| Tiago P Guedes, Sofia Martins, Madalena Costa, Sofia S Pereira, Tiago Morais, Agostinho Santos, Mário Nora, Mariana P Monteir. Detailed characterization of incretin cell distribution along the human small intestine. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. vol 11. issue 6. 2016-10-05. PMID:26048514. |
incretin hormones, glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide 1 (glp-1), are physiologic stimulants of insulin release that have been implicated in diabetes remission after bariatric surgery. |
2016-10-05 |
2023-08-13 |
human |
| Yanwei Li, WeiZhen Liu, Lin Li, Christian Hölsche. Neuroprotective effects of a GIP analogue in the MPTP Parkinson's disease mouse model. Neuropharmacology. vol 101. 2016-10-05. PMID:26453962. |
glucose-dependent insulinotropic polypeptide (gip) belongs to the incretin hormone family, which can promote insulin release and improve insulin resistance. |
2016-10-05 |
2023-08-13 |
mouse |
| P J B Millar, V Pathak, R C Moffett, N M Pathak, A J Bjourson, M J O'Kane, P R Flatt, V A Gaul. Beneficial metabolic actions of a stable GIP agonist following pre-treatment with a SGLT2 inhibitor in high fat fed diabetic mice. Molecular and cellular endocrinology. vol 420. 2016-09-30. PMID:26607806. |
once-daily administration of (dala(2))gip for 14 days in high fat fed diabetic mice pre-treated with dapa demonstrated significant decrease in body weight, blood glucose and increased insulin concentrations which were independent of changes in energy intake. |
2016-09-30 |
2023-08-13 |
mouse |
| C J McMillan, R C Zapata, P K Chelikani, E C R Snead, K Cosfor. Circulating concentrations of glucagon-like peptide 1, glucose-dependent insulinotropic peptide, peptide YY, and insulin in client-owned lean, overweight, and diabetic cats. Domestic animal endocrinology. vol 54. 2016-09-30. PMID:26609567. |
results showed that plasma concentrations of glp-1, gip, pyy, and insulin increased in general after a meal in all study groups. |
2016-09-30 |
2023-08-13 |
Not clear |
| Baptist Gallwit. Glucagon-like peptide-1 and gastric inhibitory polypeptide: new advances. Current opinion in endocrinology, diabetes, and obesity. vol 23. issue 1. 2016-09-27. PMID:26702848. |
glucagon-like peptide-1 (glp-1) and gastric inhibitory polypeptide (gip) are gastrointestinal peptides that play an important role as incretin hormones in the regulation of plasma glucose and insulin secretion. |
2016-09-27 |
2023-08-13 |
Not clear |
| Hidetaka Hamasaki, Sumie Moriyama, Hidekatsu Yana. A possible difference in the mechanism for postprandial hypoglycemia associated with dumping syndrome between patients with and without type 2 diabetes. Obesity research & clinical practice. vol 9. issue 6. 2016-09-22. PMID:26321136. |
we investigated the changes in plasma glucose, serum insulin, plasma glucagon, glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (glp-1) by the 75 g oral glucose tolerance test (ogtt) in 3 patients with and without type 2 diabetes who had gastric surgery. |
2016-09-22 |
2023-08-13 |
Not clear |
| Ujwal R Yanala, Roger D Reidelberger, Jon S Thompson, Valerie K Shostrom, Mark A Carlso. Effect of proximal versus distal 50% enterectomy on nutritional parameters in rats preconditioned with a high-fat diet or regular chow. Scientific reports. vol 5. 2016-09-22. PMID:26612764. |
enterectomy moderated serum ghrelin, gip, ppy, insulin, and leptin. |
2016-09-22 |
2023-08-13 |
rat |
| Paul L McCormac. Evogliptin: First Global Approval. Drugs. vol 75. issue 17. 2016-09-09. PMID:26541763. |
dpp-4 inhibitors control glucose levels by preventing the breakdown of the incretin hormones glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (glp-1), which stimulate insulin secretion in response to the increased levels of glucose in the period following meals. |
2016-09-09 |
2023-08-13 |
Not clear |
| Csaba Hegedűs, Diána Kovács, Rita Kiss, Réka Sári, József Németh, Zoltán Szilvássy, Barna Peit. Effect of long-term olanzapine treatment on meal-induced insulin sensitization and on gastrointestinal peptides in female Sprague-Dawley rats. Journal of psychopharmacology (Oxford, England). vol 29. issue 12. 2016-09-07. PMID:26349558. |
fasted and post-prandial blood samples were obtained for plasma insulin, leptin, ghrelin, amylin, glp-1, gip, pyy and pp determination. |
2016-09-07 |
2023-08-13 |
rat |
| Maria S Svane, Kirstine N Bojsen-Møller, Signe Nielsen, Nils B Jørgensen, Carsten Dirksen, Flemming Bendtsen, Viggo B Kristiansen, Bolette Hartmann, Jens J Holst, Sten Madsba. Effects of endogenous GLP-1 and GIP on glucose tolerance after Roux-en-Y gastric bypass surgery. American journal of physiology. Endocrinology and metabolism. vol 310. issue 7. 2016-08-23. PMID:26786780. |
this study confirms the importance of glp-1 for glucose tolerance after rygb via increased insulin and attenuated glucagon secretion in the postprandial state, whereas amplification of the gip signal (or other dpp-4-sensitive glucose-lowering mechanisms) did not appear to contribute to the improved glucose tolerance seen after rygb. |
2016-08-23 |
2023-08-13 |
Not clear |
| Naresh Ramesh, Sima Mortazavi, Suraj Unniappa. Nesfatin-1 stimulates cholecystokinin and suppresses peptide YY expression and secretion in mice. Biochemical and biophysical research communications. vol 472. issue 1. 2016-08-08. PMID:26920055. |
post-prandial insulin secretion is predominantly regulated by incretins glucagon-like peptide 1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip). |
2016-08-08 |
2023-08-13 |
mouse |
| Simone Queiroz Pantaleão, Vinicius Gonçalves Maltarollo, Sheila Cruz Araujo, Jadson Castro Gertrudes, Kathia Maria Honori. Molecular docking studies and 2D analyses of DPP-4 inhibitors as candidates in the treatment of diabetes. Molecular bioSystems. vol 11. issue 11. 2016-08-01. PMID:26399297. |
dipeptidyl peptidase-4 (dpp-4) is an important biological target related to the treatment of diabetes as dpp-4 inhibitors can lead to an increase in the insulin levels and a prolonged activity of glucagon-like peptide-1 (glp-1) and gastric inhibitory polypeptide (gip), being effective in glycemic control. |
2016-08-01 |
2023-08-13 |
Not clear |
| Cathrine Laustrup Møller, Dorte Vistisen, Kristine Færch, Nanna Borup Johansen, Daniel R Witte, Anna Jonsson, Oluf Pedersen, Torben Hansen, Torsten Lauritzen, Marit E Jørgensen, Signe S Torekov, Jens Juul Hols. Glucose-Dependent Insulinotropic Polypeptide Is Associated With Lower Low-Density Lipoprotein But Unhealthy Fat Distribution, Independent of Insulin: The ADDITION-PRO Study. The Journal of clinical endocrinology and metabolism. vol 101. issue 2. 2016-07-06. PMID:26505824. |
however, given that gip promotes release of insulin by the pancreas and insulin is anti-lipolytic, the effect may be indirect. |
2016-07-06 |
2023-08-13 |
Not clear |