| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Altomonte, A Zoli, G Ghirlanda, R Manna, A V Grec. Effect of fenfluramine on insulin/growth hormone ratio in obese subjects. Pharmacology. vol 36. issue 2. 1988-04-28. PMID:3281173. |
because insulin promotes fat and carbohydrate storage while gh stimulates lipolysis, the combination of high insulin and low gh concentrations may worsen the obese condition. |
1988-04-28 |
2023-08-11 |
human |
| M Kollind, U Adamson, P E Lins, T Cursted. Importance of growth hormone for blood glucose regulation following insulin-induced nocturnal hypoglycemia in insulin-dependent diabetes mellitus. Acta medica Scandinavica. vol 223. issue 2. 1988-04-21. PMID:2894751. |
it is concluded that when hypoglycemia is accompanied by a transient increase in plasma gh, insulin resistance occurs after a lag period of approximately 4 hours and that this effect persists for at least another 4 hours. |
1988-04-21 |
2023-08-11 |
Not clear |
| M Kelijman, L A Frohma. Discordant effects of insulin-hypoglycemia on growth hormone (GH)-releasing hormone-stimulated GH and thyrotropin (TSH)-releasing hormone-stimulated TSH secretion. The Journal of clinical endocrinology and metabolism. vol 66. issue 4. 1988-04-19. PMID:3126217. |
the hypothesis that insulin hypoglycemia-induced gh release is mediated by a decrease in hypothalamic somatostatin (srih) secretion was tested by investigating whether insulin administration enhanced the responses of srih-sensitive pituitary hormones to hypothalamic hormone stimulation. |
1988-04-19 |
2023-08-11 |
Not clear |
| M Kelijman, L A Frohma. Discordant effects of insulin-hypoglycemia on growth hormone (GH)-releasing hormone-stimulated GH and thyrotropin (TSH)-releasing hormone-stimulated TSH secretion. The Journal of clinical endocrinology and metabolism. vol 66. issue 4. 1988-04-19. PMID:3126217. |
insulin hypoglycemia augmented the maximal incremental (p less than 0.01) and integrated (p less than 0.025) plasma gh responses to ghrh. |
1988-04-19 |
2023-08-11 |
Not clear |
| M B Davidson, D C Shen, N Venkatesan, G Slade. In vivo insulin antagonism but evanescent in vitro tissue effect in rats with growth hormone-secreting tumors. Journal of endocrinological investigation. vol 10. issue 6. 1988-04-15. PMID:3326890. |
to determine if growth hormone (gh) secreted by these tumors causes insulin antagonism, pancreatic suppression tests utilizing infusions (per kg per min) of glucose (8 mg), insulin (200 ng) and somatostatin (1.4 micrograms) for 130 min were performed. |
1988-04-15 |
2023-08-11 |
rat |
| M B Davidson, D C Shen, N Venkatesan, G Slade. In vivo insulin antagonism but evanescent in vitro tissue effect in rats with growth hormone-secreting tumors. Journal of endocrinological investigation. vol 10. issue 6. 1988-04-15. PMID:3326890. |
this suggests that the changes induced by gh in vivo that lead to insulin antagonism are short-lived. |
1988-04-15 |
2023-08-11 |
rat |
| K Sanayama, H Noda, S Konda, F Ikeda, A Murata, N Sasaki, H Niimi, H Nakajim. Spontaneous growth hormone secretion and plasma somatomedin-C in children of short stature. Endocrinologia japonica. vol 34. issue 5. 1988-03-30. PMID:3436297. |
the mean concentration of gh (mcgh) was calculated and was compared with the subjects' gh responses to insulin and arginine tolerance tests (iatt) and plasma somatomedin-c (sm-c). |
1988-03-30 |
2023-08-11 |
human |
| C Wang, K S Lam, J T Ma, T Chan, M Y Liu, R T Yeun. Long-term treatment of hyperprolactinaemia with bromocriptine: effect of drug withdrawal. Clinical endocrinology. vol 27. issue 3. 1988-03-18. PMID:3427794. |
one of the patients had impaired gh response to insulin hypoglycaemia developing after radiotherapy. |
1988-03-18 |
2023-08-11 |
human |
| A T Soliman, M K Aref, A D Rogo. Arginine-induced insulin and growth hormone secretion in children with nutritional rickets. Journal of pediatric gastroenterology and nutrition. vol 6. issue 4. 1988-03-15. PMID:3323444. |
we evaluated arginine-induced insulin and growth hormone (gh) secretion in ten children with vitamin d deficiency rickets and compared these values with those of eight age-matched control children. |
1988-03-15 |
2023-08-11 |
Not clear |
| A T Soliman, M K Aref, A D Rogo. Arginine-induced insulin and growth hormone secretion in children with nutritional rickets. Journal of pediatric gastroenterology and nutrition. vol 6. issue 4. 1988-03-15. PMID:3323444. |
after an intravenous infusion of arginine-hcl (10% solution, 0.5 g/kg), blood samples were obtained for the measurement of serum insulin and gh concentrations. |
1988-03-15 |
2023-08-11 |
Not clear |
| D M Wilson, J W Frane, B Sherman, A J Johanson, R L Hintz, R G Rosenfel. Carbohydrate and lipid metabolism in Turner syndrome: effect of therapy with growth hormone, oxandrolone, and a combination of both. The Journal of pediatrics. vol 112. issue 2. 1988-03-14. PMID:3276862. |
to evaluate the effects of growth-promoting therapy on carbohydrate metabolism in girls with turner syndrome, we determined glucose and insulin concentrations during oral glucose tolerance tests (ogtts) at baseline and after 5 days, 2 months, and 12 months of treatment with growth hormone (gh), oxandrolone, or a combination of gh and oxandrolone, or after the same intervals with no therapy. |
1988-03-14 |
2023-08-11 |
human |
| M Obara, H Mizunuma, Y Ibuki, M Igarash. [Endocrinological background of pituitary desensitization during pulsatile LH-RH therapy for ovulation induction in amenorrheic women]. Nihon Sanka Fujinka Gakkai zasshi. vol 39. issue 10. 1988-03-03. PMID:3323357. |
however, in the desensitized group, all were obese, showed impaired gh response to both insulin tolerance and gh-rh tests, and had episodic lh secretion with higher frequency compared to the ovulated group. |
1988-03-03 |
2023-08-11 |
Not clear |
| M Rosenbaum, S Loche, S Balzano, J M Gertne. Short-term met-hGH infusion inhibits somatotroph response to growth hormone releasing hormone (1-44). Metabolism: clinical and experimental. vol 37. issue 2. 1988-03-02. PMID:3123873. |
they also suggest that acute mediation of gh release must occur, at least in part, at the pituitary somatotroph level and that igfs and/or insulin may not be the primary inhibitors. |
1988-03-02 |
2023-08-11 |
human |
| S Lacoumenta, T H Yeo, J M Burrin, J L Paterson, G M Hal. The effects of cortisol supplementation on the metabolic and hormonal response to surgery. Clinical physiology (Oxford, England). vol 7. issue 6. 1988-02-29. PMID:2827943. |
however, this marked hypercortisolaemia had no significant effects on circulating metabolites other than glucose, and did not alter plasma acth, gh and insulin values. |
1988-02-29 |
2023-08-11 |
human |
| S W Lambert. A guide to the clinical use of the somatostatin analogue SMS 201-995 (Sandostatin). Acta endocrinologica. Supplementum. vol 286. 1988-02-17. PMID:2892338. |
sms 201-995 (sandostatin) is an octapeptide which differs in its action from native somatostatin in four ways: 1) it inhibits gh hormone secretion in preference to insulin secretion; 2) it can be administered subcutaneously or even orally; 3) it is long-acting (t1/2 after sc administration 113 min), and 4) there is no rebound hypersecretion of hormones when the effect of the analogue lingers off. |
1988-02-17 |
2023-08-11 |
Not clear |
| R Rosskamp, M Becker, F Haverkamp, B Thomas, S Brühl, J Klumpp, N Liappi. Plasma levels of growth hormone-releasing hormone and somatostatin in response to a mixed meal and during sleep in children. Acta endocrinologica. vol 116. issue 4. 1988-02-08. PMID:2892332. |
following a mixed meal, plasma levels of ghrh, gh, srih and insulin were measured in 7 prepubertal children with constitutional delay of growth and adolescence (cdga) and in 3 children with proven gh-deficiency which responded to ghrh-injection. |
1988-02-08 |
2023-08-11 |
Not clear |
| R Rosskamp, M Becker, F Haverkamp, B Thomas, S Brühl, J Klumpp, N Liappi. Plasma levels of growth hormone-releasing hormone and somatostatin in response to a mixed meal and during sleep in children. Acta endocrinologica. vol 116. issue 4. 1988-02-08. PMID:2892332. |
no time relationship was present between circulating ghrh and gh, srih, or insulin, nor was there any correlation between their integrated hormone response areas. |
1988-02-08 |
2023-08-11 |
Not clear |
| M Iovino, P Monteleone, L Steard. Combined alpha-adrenergic stimulation results in biphasic response of growth hormone release in man. The Journal of clinical endocrinology and metabolism. vol 66. issue 1. 1988-02-02. PMID:2826526. |
to further characterize the role of adrenergic transmission in the regulation of gh release, the effects of combined administration of clonidine and insulin were investigated in 16 normal men randomly assigned to 2 groups. |
1988-02-02 |
2023-08-11 |
Not clear |
| M Iovino, P Monteleone, L Steard. Combined alpha-adrenergic stimulation results in biphasic response of growth hormone release in man. The Journal of clinical endocrinology and metabolism. vol 66. issue 1. 1988-02-02. PMID:2826526. |
insulin induced a clear-cut increase in plasma gh (f = 79.88; p less than 0.001) that was not affected by placebo, whereas it was significantly inhibited by oral clonidine (p less than 0.001 at 60, 90, and 120 min). |
1988-02-02 |
2023-08-11 |
Not clear |
| M Iovino, P Monteleone, L Steard. Combined alpha-adrenergic stimulation results in biphasic response of growth hormone release in man. The Journal of clinical endocrinology and metabolism. vol 66. issue 1. 1988-02-02. PMID:2826526. |
similarly, oral clonidine administration resulted in a clear-cut rise in plasma gh levels (f = 16.44; p less than 0.001) that was significantly reduced by insulin (p less than 0.001, p less than 0.02, and p less than 0.05 at 60, 90, and 120 min, respectively). |
1988-02-02 |
2023-08-11 |
Not clear |