| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Kollind, U Adamson, P E Lin. Somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. Acta endocrinologica. vol 118. issue 2. 1988-08-04. PMID:2898855. |
it is therefore suggested that an analogue with a specific gh release inhibiting property may be useful in reducing glycemic instability when given as adjunct therapy to insulin in patients with labile glycemic control. |
1988-08-04 |
2023-08-11 |
Not clear |
| J O Jørgensen, A Flyvbjerg, T Lauritzen, K G Alberti, H Orskov, J S Christianse. Dose-response studies with biosynthetic human growth hormone (GH) in GH-deficient patients. The Journal of clinical endocrinology and metabolism. vol 67. issue 1. 1988-07-28. PMID:3288652. |
breakfast induced a plasma glucose rise when gh was administered, but no rise without gh, and a postprandial serum insulin response that was gh dose dependent. |
1988-07-28 |
2023-08-11 |
human |
| R Keret, Z Josefsberg, H Kinarti, A Silbergeld, B Szoke, A V Schally, Z Laro. Discrimination between growth hormone (GH) deficiency of hypothalamic or pituitary origin: an aid in selecting patients for GH-releasing hormone (RH) prolonged therapy. Israel journal of medical sciences. vol 24. issue 4-5. 1988-07-27. PMID:3132434. |
gh-rh tests (1 mu/kg); 7 had idiopathic gh deficiency (ighd) and 4 had multiple pituitary hormone deficiencies (mphd)--diagnosed on the basis of the insulin hypoglycemia, clonidine and sleep tests. |
1988-07-27 |
2023-08-11 |
human |
| N A Cole, C W Purdy, D M Hallfor. Influence of fasting and post-fast diet energy level on feed intake, feeding pattern and blood variables of lambs. Journal of animal science. vol 66. issue 3. 1988-07-27. PMID:3288601. |
trials were conducted to determine the influence of feed and water deprivation on feed intake, plasma glucose, free fatty acids (ffa), urea-n (pun), serum insulin and growth hormone (gh) in lambs. |
1988-07-27 |
2023-08-11 |
Not clear |
| N A Cole, C W Purdy, D M Hallfor. Influence of fasting and post-fast diet energy level on feed intake, feeding pattern and blood variables of lambs. Journal of animal science. vol 66. issue 3. 1988-07-27. PMID:3288601. |
on d 4 of realimentation, lambs previously fasted had higher insulin:gh ratios and lower pun than controls. |
1988-07-27 |
2023-08-11 |
Not clear |
| P Pietschmann, G Schernthane. The effect of pirenzepine on growth hormone and blood glucose levels in type I diabetes mellitus. A controlled study in patients on basal bolus insulin treatment. Acta endocrinologica. vol 117. issue 3. 1988-07-27. PMID:3289300. |
in 21 type i diabetic patients the effect of oral administration of the anticholinergic drug pirenzepine in addition to intensive insulin therapy on gh and blood glucose levels was studied. |
1988-07-27 |
2023-08-11 |
Not clear |
| P Hindmarsh, P J Smith, C G Brook, D R Matthew. The relationship between height velocity and growth hormone secretion in short prepubertal children. Clinical endocrinology. vol 27. issue 5. 1988-07-05. PMID:3450456. |
similar overlap was observed when the results of gh responses to insulin induced hypoglycaemia were considered; 14% of slowly growing children (height velocity sds less than -0.8), had a response greater than 15 mu/l. |
1988-07-05 |
2023-08-11 |
Not clear |
| J Słowińska-Srzednicka, S Zgliczyński, M Wierzbicki, P Soszyński, W Jesk. Growth hormone (GH) secretion during nocturnal sleep and after clonidine in patients with essential hypertension. Clinical and experimental hypertension. Part A, Theory and practice. vol 10. issue 2. 1988-07-01. PMID:3286064. |
however, the negative correlation between the fasting insulin concentration and gh response to clonidine shown in obese subjects only, points to a more complex mechanism of gh inhibition in obesity. |
1988-07-01 |
2023-08-11 |
human |
| N Rigaudière, S Loubassou, G Grizard, D Bouche. Characterization of insulin binding and comparative action of insulin and insulin-like growth factor I on purified Leydig cells from the adult rat. International journal of andrology. vol 11. issue 2. 1988-06-29. PMID:3286525. |
competition relative to porcine insulin (100) was as follows: insulin-like growth factor i (igf-i) : less than 1; proinsulin : 5; guinea-pig insulin : 2; hcg, ovine prolactin and bovine gh : 0. |
1988-06-29 |
2023-08-11 |
rat |
| L G Frigeri, C Teguh, N Ling, G L Wolff, U J Lewi. Increased sensitivity of adipose tissue to insulin after in vivo treatment of yellow Avy/A obese mice with amino-terminal peptides of human growth hormone. Endocrinology. vol 122. issue 6. 1988-06-28. PMID:3131129. |
treatment of obese yellow avy/a mice with the human gh (hgh) peptide hgh-(1-43) enhanced the in vitro sensitivity of their adipose tissue to insulin. |
1988-06-28 |
2023-08-11 |
mouse |
| B Formby, A Ullrich, L Coussens, L Walker, C M Peterso. Growth hormone stimulates insulin gene expression in cultured human fetal pancreatic islets. The Journal of clinical endocrinology and metabolism. vol 66. issue 5. 1988-06-03. PMID:3283160. |
since insulin has an essential growth-promoting influence in the fetus, these experiments were designed to determine whether gh can function as a growth factor with insulin-releasing activity by stimulating insulin gene expression during embryogenesis. |
1988-06-03 |
2023-08-11 |
human |
| B Formby, A Ullrich, L Coussens, L Walker, C M Peterso. Growth hormone stimulates insulin gene expression in cultured human fetal pancreatic islets. The Journal of clinical endocrinology and metabolism. vol 66. issue 5. 1988-06-03. PMID:3283160. |
we conclude that recombinant human gh significantly enhances the steady state level of insulin mrna concurrent with an increase in insulin secretory capacity, hence providing evidence for a regulatory function of gh on insulin gene expression during fetal development. |
1988-06-03 |
2023-08-11 |
human |
| S Guller, R E Corin, D C Mynarcik, B M London, M Sonenber. Role of insulin in growth hormone-stimulated 3T3 cell adipogenesis. Endocrinology. vol 122. issue 5. 1988-06-01. PMID:3282874. |
adipogenesis in defined medium (dm), as quantified by the level of glycerol-3-phosphate dehydrogenase activity, revealed that there existed a strict requirement for both insulin and gh during adipogenesis. |
1988-06-01 |
2023-08-11 |
human |
| S Guller, R E Corin, D C Mynarcik, B M London, M Sonenber. Role of insulin in growth hormone-stimulated 3T3 cell adipogenesis. Endocrinology. vol 122. issue 5. 1988-06-01. PMID:3282874. |
deletion of insulin from dm supplemented with 1 nm recombinant human gh reduced glycerol-3-phosphate dehydrogenase activity to uninduced levels. |
1988-06-01 |
2023-08-11 |
human |
| S Guller, R E Corin, D C Mynarcik, B M London, M Sonenber. Role of insulin in growth hormone-stimulated 3T3 cell adipogenesis. Endocrinology. vol 122. issue 5. 1988-06-01. PMID:3282874. |
these results suggest that insulin functions in concert with gh as a coinducer of the differentiating signals. |
1988-06-01 |
2023-08-11 |
human |
| D J Brunswick, A Frazer, S H Koslow, R Casper, P E Stokes, E Robins, J M Davi. Insulin-induced hypoglycaemic response and release of growth hormone in depressed patients and healthy controls. Psychological medicine. vol 18. issue 1. 1988-05-31. PMID:3283809. |
as part of the collaborative study of the psychobiology of depression, we have examined the pretreatment growth hormone response (delta gh) to insulin (0.1 u/kg) and the magnitude of the hypoglycaemic response in a large number of well-defined depressed patients (n = 132) and healthy controls (n = 80). |
1988-05-31 |
2023-08-11 |
Not clear |
| D J Brunswick, A Frazer, S H Koslow, R Casper, P E Stokes, E Robins, J M Davi. Insulin-induced hypoglycaemic response and release of growth hormone in depressed patients and healthy controls. Psychological medicine. vol 18. issue 1. 1988-05-31. PMID:3283809. |
these data do not support previous claims of a lowered delta gh response to insulin in depressed patients. |
1988-05-31 |
2023-08-11 |
Not clear |
| P Garnier, C Liapi, F Raynaud, D Evain-Brio. Comparison of growth hormone response to growth hormone-releasing factor 1-44 according to the combined study of sleep secretion with the responses to pharmacologic stimuli. Hormone research. vol 28. issue 1. 1988-05-27. PMID:3129352. |
the patients were also submitted to a standard evaluation of their gh secretion, consisting of at least two classical pharmacologic stimulation (cps) tests, such as ornithine, arginine and/or insulin, and one study of the gh sleep secretion (ss). |
1988-05-27 |
2023-08-11 |
Not clear |
| L Altomonte, A Zoli, G Ghirlanda, R Manna, A V Grec. Effect of fenfluramine on insulin/growth hormone ratio in obese subjects. Pharmacology. vol 36. issue 2. 1988-04-28. PMID:3281173. |
obesity is characterized by increased levels of insulin and by subnormal growth hormone (gh) release. |
1988-04-28 |
2023-08-11 |
human |
| L Altomonte, A Zoli, G Ghirlanda, R Manna, A V Grec. Effect of fenfluramine on insulin/growth hormone ratio in obese subjects. Pharmacology. vol 36. issue 2. 1988-04-28. PMID:3281173. |
blood samples were taken every 30 min until 270 min for gh and insulin radioimmunoassay. |
1988-04-28 |
2023-08-11 |
human |