| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Kollin. Studies on posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus. Acta medica Scandinavica. Supplementum. vol 727. 1988-12-16. PMID:2903616. |
these studies therefore indicate that the gh suppressing hormone somatostatin may be of clinical value as an adjunct to insulin in the treatment of patients with insulin-dependent diabetes mellitus and labile blood glucose control. |
1988-12-16 |
2023-08-11 |
Not clear |
| D Prager, S Melme. Insulin regulates expression of the human growth hormone gene in transfected cells. The Journal of biological chemistry. vol 263. issue 32. 1988-12-14. PMID:2903152. |
insulin has been shown to inhibit rat growth hormone (gh) gene transcription. |
1988-12-14 |
2023-08-11 |
human |
| D Prager, S Melme. Insulin regulates expression of the human growth hormone gene in transfected cells. The Journal of biological chemistry. vol 263. issue 32. 1988-12-14. PMID:2903152. |
the effects of insulin were therefore tested on the expression of a transfected human gh gene. |
1988-12-14 |
2023-08-11 |
human |
| D Prager, S Melme. Insulin regulates expression of the human growth hormone gene in transfected cells. The Journal of biological chemistry. vol 263. issue 32. 1988-12-14. PMID:2903152. |
immunoprecipitation analysis showed that insulin (0.7-7 nm) suppressed both the basal as well as the hydrocortisone (100 nm)-stimulated expression of newly synthesized 22-kda gh in a dose-dependent fashion. |
1988-12-14 |
2023-08-11 |
human |
| D Prager, S Melme. Insulin regulates expression of the human growth hormone gene in transfected cells. The Journal of biological chemistry. vol 263. issue 32. 1988-12-14. PMID:2903152. |
insulin (7 nm) also suppressed the basal and hydrocortisone-stimulated gh mrna transcripts in these cells. |
1988-12-14 |
2023-08-11 |
human |
| D Prager, S Melme. Insulin regulates expression of the human growth hormone gene in transfected cells. The Journal of biological chemistry. vol 263. issue 32. 1988-12-14. PMID:2903152. |
cells transfected with the truncated pogh gene and ptkgh gene failed to respond to insulin treatment, whereas the human gh promoter was able to confer insulin responsiveness to the chloramphenicol acetyltransferase reporter gene. |
1988-12-14 |
2023-08-11 |
human |
| D Prager, S Melme. Insulin regulates expression of the human growth hormone gene in transfected cells. The Journal of biological chemistry. vol 263. issue 32. 1988-12-14. PMID:2903152. |
cis-acting regulatory sequences residing on the 497-base pair 5'-flanking region of the human gh gene therefore appear to be a requirement for human gh gene response to the insulin signal. |
1988-12-14 |
2023-08-11 |
human |
| D G McClary, J L Sartin, R J Kemppainen, J C William. Insulin and growth hormone responses to glucose infusion in mature and first-lactation dairy cows. American journal of veterinary research. vol 49. issue 10. 1988-12-12. PMID:3056137. |
serum was obtained and was assayed for glucose, immunoreactive insulin (iri), growth hormone (gh), and free fatty acid concentrations. |
1988-12-12 |
2023-08-11 |
cattle |
| J M Wit, M A van't Hof, J L Van den Brand. The effect of human growth hormone therapy on skinfold thickness in growth hormone-deficient children. European journal of pediatrics. vol 147. issue 6. 1988-12-01. PMID:3053189. |
a larger decrease of triceps st was associated with lower gh and insulin peaks, and lower age, bone age and initial weight-for-height. |
1988-12-01 |
2023-08-11 |
human |
| S Kajiwara, N Igarashi, E Imura, T Sat. Correlation between pituitary growth hormone reserve and degree of growth failure in children with short stature. European journal of pediatrics. vol 147. issue 6. 1988-12-01. PMID:3141190. |
based on the responsiveness of gh to gh-releasing hormone (ghrh), group i, with low gh responses (below 7 ng/ml) to both insulin and arginine, was classified into three subgroups; ia (peak value less than 10 ng/ml, n = 19), ib (10-20 ng/ml, n = 5) and ic (above 20 ng/ml, n = 6). |
1988-12-01 |
2023-08-11 |
Not clear |
| S Kajiwara, N Igarashi, E Imura, T Sat. Correlation between pituitary growth hormone reserve and degree of growth failure in children with short stature. European journal of pediatrics. vol 147. issue 6. 1988-12-01. PMID:3141190. |
group ii, with a gh response above 10 ng/ml to either insulin or arginine, was also divided into iia (below 20 ng/ml, n = 5) and iib (above 20 ng/ml, n = 14). |
1988-12-01 |
2023-08-11 |
Not clear |
| Y Okimura, K Chihara, T Kita, Y Kashio, M Sato, N Kitajima, H Abe, K Takahashi, T Fujit. Discordance between growth hormone (GH) responses after GH-releasing hormone and insulin hypoglycemia in myotonic dystrophy. The Journal of clinical endocrinology and metabolism. vol 67. issue 5. 1988-12-01. PMID:3141449. |
discordance between growth hormone (gh) responses after gh-releasing hormone and insulin hypoglycemia in myotonic dystrophy. |
1988-12-01 |
2023-08-11 |
human |
| R C Casper, G N Pandy, J B Jaspan, A H Rubenstei. Hormone and metabolite plasma levels after oral glucose in bulimia and healthy controls. Biological psychiatry. vol 24. issue 6. 1988-11-23. PMID:3048427. |
glucose utilization and the insulin, glucagon, growth hormone (gh), and pancreatic polypeptide (pp) response curves in the bulimic patients were within the normal range. |
1988-11-23 |
2023-08-11 |
Not clear |
| R C Casper, G N Pandy, J B Jaspan, A H Rubenstei. Hormone and metabolite plasma levels after oral glucose in bulimia and healthy controls. Biological psychiatry. vol 24. issue 6. 1988-11-23. PMID:3048427. |
fasting plasma levels of glucose, insulin, glucagon, gh, cortisol, free fatty acids (ffa), and pp were not different from controls. |
1988-11-23 |
2023-08-11 |
Not clear |
| N A Adamafio, C M Cameron, J L Kosty. Influence of cycloheximide on acute diabetogenic effects of S-carboxymethylated human growth hormone in obese (ob/ob) mice. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 7. 1988-11-22. PMID:3049288. |
acute treatment of ob/ob mice with s-carboxymethylated hgh (rcm-hgh), a diabetogenic derivative of gh which lacks significant insulin-like and growth-promoting activities, results in an increase in fasting plasma insulin and blood glucose levels and enhanced peripheral tissue insulin resistance. |
1988-11-22 |
2023-08-11 |
mouse |
| N A Adamafio, C M Cameron, J L Kosty. Influence of cycloheximide on acute diabetogenic effects of S-carboxymethylated human growth hormone in obese (ob/ob) mice. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 20. issue 7. 1988-11-22. PMID:3049288. |
also, the gh derivative attenuated the ability of insulin added in vitro to stimulate glucose oxidation by adipose tissue segments isolated from the animals. |
1988-11-22 |
2023-08-11 |
mouse |
| P G Kopelman, A C Mason, K Noonan, J P Monso. Growth hormone response to growth hormone releasing factor in diabetic men. Clinical endocrinology. vol 28. issue 1. 1988-11-22. PMID:3139333. |
this impairment of gh secretion was unrelated to either fasting plasma insulin or glucose concentration. |
1988-11-22 |
2023-08-11 |
Not clear |
| E Ghigo, E Mazza, E Imperiale, P Molinatti, A Bertagna, F Camanni, F Massar. Growth hormone responses to pyridostigmine in normal adults and in normal and short children. Clinical endocrinology. vol 27. issue 6. 1988-10-27. PMID:3331977. |
in sc the insulin hypoglycaemia (ih)-induced gh increase was also studied. |
1988-10-27 |
2023-08-11 |
Not clear |
| K C Glenn, K S Rose, G G Kriv. Somatotropin antagonism of insulin-stimulated glucose utilization in 3T3-L1 adipocytes. Journal of cellular biochemistry. vol 37. issue 4. 1988-10-25. PMID:3047155. |
it is well established that somatotropin (gh) antagonizes insulin action in vivo and that supraphysiologic concentrations of gh frequently result in insulin resistance and glucose intolerance. |
1988-10-25 |
2023-08-11 |
human |
| K C Glenn, K S Rose, G G Kriv. Somatotropin antagonism of insulin-stimulated glucose utilization in 3T3-L1 adipocytes. Journal of cellular biochemistry. vol 37. issue 4. 1988-10-25. PMID:3047155. |
it was found that glucose utilization in 3t3-l1 adipocytes is regulated in a reciprocal fashion by insulin and gh. |
1988-10-25 |
2023-08-11 |
human |