| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M D Katz, B L Ersta. Octreotide, a new somatostatin analogue. Clinical pharmacy. vol 8. issue 4. 1989-06-22. PMID:2653711. |
like ss, octreotide suppresses secretion of pituitary growth hormone (gh) and thyrotropin and decreases release of a variety of pancreatic islet cell hormones including insulin, glucagon, and vasoactive intestinal peptide (vip). |
1989-06-22 |
2023-08-11 |
Not clear |
| R Aihara, T Hashimot. [Neuroendocrinologic studies on autism]. No to hattatsu = Brain and development. vol 21. issue 2. 1989-06-19. PMID:2713159. |
in insulin provocation test, the peak values of gh and delta gh (peak gh level minus baseline gh level) in add were significantly higher than those in mr (p less than 0.05). |
1989-06-19 |
2023-08-11 |
human |
| J M Horodnicki, J Pobocha, S Czekalski, J Wdowiak, A Szakowsk. [Relations between therapeutic and hormonal response to neuroleptics of patients with paranoid schizophrenia. III. Secretion of growth hormone (GH), adrenocorticotropic hormone (ACTH), cortisol (CORT) and insulin (INS)]. Psychiatria polska. vol 22. issue 4. 1989-06-19. PMID:2907811. |
secretion of growth hormone (gh), adrenocorticotropic hormone (acth), cortisol (cort) and insulin (ins)]. |
1989-06-19 |
2023-08-11 |
Not clear |
| P J Pringle, P C Hindmarsh, L Di Silvio, J D Teale, A B Kurtz, C G Broo. The measurement and effect of growth hormone in the presence of growth hormone-binding antibodies. The Journal of endocrinology. vol 121. issue 1. 1989-06-15. PMID:2654322. |
the presence of gh antibodies did not affect the growth, plasma insulin-like growth factor-i concentrations or fasting serum insulin concentration responses to 1 year of therapy with biosynthetic human gh. |
1989-06-15 |
2023-08-11 |
human |
| D D Lazarus, C G Scane. Acute effects of hypophysectomy and administration of pancreatic and thyroid hormones on circulating concentrations of somatomedin-C in young chickens: relationship between growth hormone and somatomedin-C. Domestic animal endocrinology. vol 5. issue 4. 1989-06-15. PMID:3073038. |
on the other hand, the administration of either glucagon or insulin decreased the plasma concentration of both gh and smc. |
1989-06-15 |
2023-08-11 |
Not clear |
| Y F Shi, X D Fan. Reduction of the effects of growth hormone release inhibiting factor enhances plasma growth hormone response to GHRH. Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao. vol 4. issue 1. 1989-06-07. PMID:2565570. |
these results may further confirm our previous postulation (1986) that insulin hypoglycemia may increase hgh release by inhibiting hypothalamic cell secretion of gh release inhibiting factor. |
1989-06-07 |
2023-08-11 |
Not clear |
| D Maiter, T Fliesen, L E Underwood, M Maes, G Gerard, M L Davenport, J M Ketelsleger. Dietary protein restriction decreases insulin-like growth factor I independent of insulin and liver growth hormone binding. Endocrinology. vol 124. issue 5. 1989-06-06. PMID:2523305. |
to determine the role of hypoinsulinemia and liver somatogenic (gh) receptors in growth retardation and decreased serum insulin-like growth factor i (igf-i) levels during protein restriction, we have used a rat model where the effects of a low protein intake on body weight (bw), serum igf-i concentration, and liver gh binding could be evaluated in the presence of low or high insulin concentrations. |
1989-06-06 |
2023-08-11 |
rat |
| D Maiter, T Fliesen, L E Underwood, M Maes, G Gerard, M L Davenport, J M Ketelsleger. Dietary protein restriction decreases insulin-like growth factor I independent of insulin and liver growth hormone binding. Endocrinology. vol 124. issue 5. 1989-06-06. PMID:2523305. |
in the nondiabetic animals, 7 days of protein restriction reduced bw gain by 50% (p less than 0.001), serum insulin by 44% (p less than 0.025), and serum igf-i concentrations by 28% (p less than 0.001) without significantly changing liver gh binding. |
1989-06-06 |
2023-08-11 |
rat |
| D Maiter, T Fliesen, L E Underwood, M Maes, G Gerard, M L Davenport, J M Ketelsleger. Dietary protein restriction decreases insulin-like growth factor I independent of insulin and liver growth hormone binding. Endocrinology. vol 124. issue 5. 1989-06-06. PMID:2523305. |
by day 9, bw was decreased in the diabetic animals by 12%, serum insulin by 80%, serum igf-i by 55%, and liver gh binding by 62%; these effects were similar in the 5% and 15% protein-fed rats (p less than 0.001 vs. the corresponding controls). |
1989-06-06 |
2023-08-11 |
rat |
| D Maiter, T Fliesen, L E Underwood, M Maes, G Gerard, M L Davenport, J M Ketelsleger. Dietary protein restriction decreases insulin-like growth factor I independent of insulin and liver growth hormone binding. Endocrinology. vol 124. issue 5. 1989-06-06. PMID:2523305. |
in the diabetes fed the normal diet, insulin treatment restored bw gain, serum igf-i, and liver gh binding to normal values. |
1989-06-06 |
2023-08-11 |
rat |
| D Maiter, T Fliesen, L E Underwood, M Maes, G Gerard, M L Davenport, J M Ketelsleger. Dietary protein restriction decreases insulin-like growth factor I independent of insulin and liver growth hormone binding. Endocrinology. vol 124. issue 5. 1989-06-06. PMID:2523305. |
this diet-induced growth attenuation was observed despite high circulating insulin (2-3 times normal values), appropriate glucose control (63 +/- 9 mg/dl), and near restoration of liver gh binding. |
1989-06-06 |
2023-08-11 |
rat |
| B Froger-Gaillard, P Hossenlopp, M Adolphe, M Binou. Production of insulin-like growth factors and their binding proteins by rabbit articular chondrocytes: relationships with cell multiplication. Endocrinology. vol 124. issue 5. 1989-06-06. PMID:2539977. |
the effects were studied of gh, insulin-like growth factors (igfs), and insulin on the production of igf-i, igf-ii, and their binding proteins (bps) and on cell multiplication. |
1989-06-06 |
2023-08-11 |
human |
| B Froger-Gaillard, P Hossenlopp, M Adolphe, M Binou. Production of insulin-like growth factors and their binding proteins by rabbit articular chondrocytes: relationships with cell multiplication. Endocrinology. vol 124. issue 5. 1989-06-06. PMID:2539977. |
under the various conditions of culture with different doses of gh and insulin, cell multiplication, relative to the control value was positively correlated to the igf-i/igf-ii production ratio (r = 0.77). |
1989-06-06 |
2023-08-11 |
human |
| H P Guler, C Schmid, J Zapf, E R Froesc. Effects of recombinant insulin-like growth factor I on insulin secretion and renal function in normal human subjects. Proceedings of the National Academy of Sciences of the United States of America. vol 86. issue 8. 1989-05-24. PMID:2649897. |
our preliminary data allow us to distinguish between the effects of gh per se and those of igf-i: gh causes hyperinsulinism, whereas igf-i leads to decreased insulin secretion. |
1989-05-24 |
2023-08-11 |
human |
| R R Davies, S J Turner, K G Alberti, D G Johnsto. Somatostatin analogues in diabetes mellitus. Diabetic medicine : a journal of the British Diabetic Association. vol 6. issue 2. 1989-05-16. PMID:2564819. |
pharmacological suppression of gh release at this stage might reverse the metabolic changes, with the possible added benefit of lower plasma insulin concentrations. |
1989-05-16 |
2023-08-11 |
Not clear |
| R R Davies, S J Turner, K G Alberti, D G Johnsto. Somatostatin analogues in diabetes mellitus. Diabetic medicine : a journal of the British Diabetic Association. vol 6. issue 2. 1989-05-16. PMID:2564819. |
in type 1 diabetes insulin requirement is decreased by octreotide, but as in type 2 diabetes gh suppression has been observed consistently only when the drug was given at bed-time. |
1989-05-16 |
2023-08-11 |
Not clear |
| M Losa, R Oeckler, J Schopohl, O A Müller, J Alba-Lopez, K von Werde. Evaluation of selective transsphenoidal adenomectomy by endocrinological testing and somatomedin-C measurement in acromegaly. Journal of neurosurgery. vol 70. issue 4. 1989-05-05. PMID:2647918. |
pre- and postoperative evaluation consisted of measuring growth hormone (gh) secretory dynamics during an oral glucose tolerance test (ogtt), the insulin hypoglycemia test, and the thyrotropin- and gonadotropin-releasing hormone (trh/gnrh) test, and by obtaining the basal somatomedin-c level. |
1989-05-05 |
2023-08-11 |
human |
| M Losa, R Oeckler, J Schopohl, O A Müller, J Alba-Lopez, K von Werde. Evaluation of selective transsphenoidal adenomectomy by endocrinological testing and somatomedin-C measurement in acromegaly. Journal of neurosurgery. vol 70. issue 4. 1989-05-05. PMID:2647918. |
evaluation of gh secretion by insulin hypoglycemia testing was useless in assessing the outcome after neurosurgery. |
1989-05-05 |
2023-08-11 |
human |
| J A Fagin, C T Roberts, D LeRoith, A T Brow. Coordinate decrease of tissue insulinlike growth factor I posttranscriptional alternative mRNA transcripts in diabetes mellitus. Diabetes. vol 38. issue 4. 1989-05-04. PMID:2925006. |
the ratio of igf-ia to igf-ib mrna remained relatively constant for each tissue and was not affected by the diabetic state, chronic gh hyperstimulation, or insulin therapy, suggesting that posttranscriptional splicing is not a regulated event in these conditions. |
1989-05-04 |
2023-08-11 |
rat |
| K Oberg, I Norheim, E Theodorsson, H Ahlman, G Lundqvist, L Wid. The effects of octreotide on basal and stimulated hormone levels in patients with carcinoid syndrome. The Journal of clinical endocrinology and metabolism. vol 68. issue 4. 1989-04-14. PMID:2466045. |
a sc injection of 50 micrograms octreotide caused a significant (p less than 0.001) decrease in median plasma tachykinins and serum pancreatic polypeptide, gh, and insulin for up to 4 h. administration of octreotide (50 micrograms, twice daily, sc) caused a 26% decrease in urinary 5-hydroxyindoleacetia acid excretion, but the number of flushing attacks or bowel movements did not change significantly. |
1989-04-14 |
2023-08-11 |
Not clear |