| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eyad M T Ali, Hany M A Sonpo. Neuroprotective and Ameliorating Impacts of Omega-3 Against Aspartame-induced Neuronal and Astrocytic Degeneration. Anatomical record (Hoboken, N.J. : 2007). vol 300. issue 7. 2018-03-26. PMID:27998013. |
spinal cord sections were prepared and stained with hx&e, caspase-3 and gfap immunostaining. |
2018-03-26 |
2023-08-13 |
rat |
| Fangfang Sun, Tingchun Shi, Tao Zhou, Dongwei Dong, Jin Xie, Ruiyan Wang, Xiao An, Meihua Chen, Jianhui Ca. 3D Poly(Lactic-co-glycolic acid) Scaffolds for Treating Spinal Cord Injury. Journal of biomedical nanotechnology. vol 13. issue 3. 2018-02-23. PMID:29381284. |
histological assessment including glia fibrillary acidic protein (gfap) staining, nissl staining, luxol fast blue (lfb) staining and bielschowsky silver staining showed that the spinal cord recoveries considerably improved with the plga scaffolds, indicating that the plga scaffolds exhibited potential for applications in the management of spinal cord injuries. |
2018-02-23 |
2023-08-13 |
Not clear |
| Yuzhou Liu, Le Wang, Chong Meng, Yingjie Zhou, Jie Lao, Xin Zha. A new model for the study of neuropathic pain after brachial plexus injury. Injury. vol 48. issue 2. 2018-02-01. PMID:27863697. |
the injured level of spinal cord was resected and the sections were processed for gfap (astrocyte) and iba1 (microglia) immunohistochemistry 3 weeks after surgeries. |
2018-02-01 |
2023-08-13 |
rat |
| Wenjun Xu, Nadia Sachewsky, Ashkan Azimi, Maurita Hung, Andrew Gappasov, Cindi M Morshea. Myelin Basic Protein Regulates Primitive and Definitive Neural Stem Cell Proliferation from the Adult Spinal Cord. Stem cells (Dayton, Ohio). vol 35. issue 2. 2017-12-11. PMID:27573615. |
spinal cord derived pnscs are similarly rare, oct4 expressing cells that are responsive to leukemia inhibitory factor and dnscs are 4-5x more abundant and express gfap. |
2017-12-11 |
2023-08-13 |
Not clear |
| Arnulf H Koeppen, Alyssa B Becker, Jiang Qian, Benjamin B Gelman, Joseph E Mazurkiewic. Friedreich Ataxia: Developmental Failure of the Dorsal Root Entry Zone. Journal of neuropathology and experimental neurology. vol 76. issue 11. 2017-10-27. PMID:29044418. |
segments of formalin-fixed upper lumbar spinal cord of 13 homozygous and 2 compound heterozygous fa patients were sectioned longitudinally to represent drez and stained for glial fibrillary acidic protein (gfap), s100, vimentin, the central nervous system (cns)-specific myelin protein proteolipid protein, the peripheral nervous system (pns) myelin proteins pmp-22 and p0, and the schwann cell proteins laminin, alpha-dystroglycan, and periaxin. |
2017-10-27 |
2023-08-13 |
Not clear |
| Sara Adães, Lígia Almeida, Catarina S Potes, Ana Rita Ferreira, José M Castro-Lopes, Joana Ferreira-Gomes, Fani L Net. Glial activation in the collagenase model of nociception associated with osteoarthritis. Molecular pain. vol 13. 2017-10-19. PMID:28326927. |
gfap expression in astrocytes and iba-1 expression in microglia of the l3-l5 spinal cord segments was assessed by immunohistochemistry and western blot analysis. |
2017-10-19 |
2023-08-13 |
rat |
| Sara Adães, Lígia Almeida, Catarina S Potes, Ana Rita Ferreira, José M Castro-Lopes, Joana Ferreira-Gomes, Fani L Net. Glial activation in the collagenase model of nociception associated with osteoarthritis. Molecular pain. vol 13. 2017-10-19. PMID:28326927. |
in the spinal cord of collagenase-injected animals, an ipsilateral upregulation of gfap and iba-1 was also observed. |
2017-10-19 |
2023-08-13 |
rat |
| Mariana M Bertozzi, Ana C Rossaneis, Victor Fattori, Daniela T Longhi-Balbinot, Andressa Freitas, Fernando Q Cunha, José C Alves-Filho, Thiago M Cunha, Rubia Casagrande, Waldiceu A Verr. Diosmin reduces chronic constriction injury-induced neuropathic pain in mice. Chemico-biological interactions. vol 273. 2017-10-02. PMID:28625489. |
daily treatment during 7 days with diosmin inhibited cci-induced mechanical and thermal hyperalgesia by inhibiting spinal cord cytokine (il-1β, tnfα, and il-33/st2) and glial cells activation (astrocytes - gfap, iba-1, and olig2) markers mrna expression. |
2017-10-02 |
2023-08-13 |
mouse |
| Hyesook Yoon, Grant Walters, Alex R Paulsen, Isobel A Scarisbric. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PloS one. vol 12. issue 7. 2017-09-25. PMID:28700615. |
results demonstrate that gfap expression is higher in the developing and adult spinal cord relative to brain. |
2017-09-25 |
2023-08-13 |
Not clear |
| Hyesook Yoon, Grant Walters, Alex R Paulsen, Isobel A Scarisbric. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PloS one. vol 12. issue 7. 2017-09-25. PMID:28700615. |
comparisons between gfap and aldh1l1 expression suggest elevations in spinal cord gfap during the early postnatal period reflect an accelerated appearance of astrocytes, while elevations in adulthood reflect higher expression by individual astrocytes. |
2017-09-25 |
2023-08-13 |
Not clear |
| Hyesook Yoon, Grant Walters, Alex R Paulsen, Isobel A Scarisbric. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PloS one. vol 12. issue 7. 2017-09-25. PMID:28700615. |
notably, increases in spinal cord compared to whole brain gfap were paralleled by higher levels of il-6 and stat3. |
2017-09-25 |
2023-08-13 |
Not clear |
| Hyesook Yoon, Grant Walters, Alex R Paulsen, Isobel A Scarisbric. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PloS one. vol 12. issue 7. 2017-09-25. PMID:28700615. |
equivalent elevations in gfap, gfap/aldh1l1 ratios, and in il-6, were observed in primary astrocyte cultures derived from spinal cord compared to cortex. |
2017-09-25 |
2023-08-13 |
Not clear |
| Hyesook Yoon, Grant Walters, Alex R Paulsen, Isobel A Scarisbric. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PloS one. vol 12. issue 7. 2017-09-25. PMID:28700615. |
also, higher levels of gfap were observed in the spinal cord compared to the brain after focal demyelinating injury. |
2017-09-25 |
2023-08-13 |
Not clear |
| Hyesook Yoon, Grant Walters, Alex R Paulsen, Isobel A Scarisbric. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PloS one. vol 12. issue 7. 2017-09-25. PMID:28700615. |
altogether, these studies point to key differences in astrocyte abundance and the expression of gfap and il-6 across the brain and spinal cord that are positioned to influence regional specialization developmentally and responses occurring in the context of injury and disease. |
2017-09-25 |
2023-08-13 |
Not clear |
| Michal K Oklinski, Jung-Suk Lim, Hyo-Jung Choi, Paulina Oklinska, Mariusz T Skowronski, Tae-Hwan Kwo. Immunolocalization of Water Channel Proteins AQP1 and AQP4 in Rat Spinal Cord. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 62. issue 8. 2017-09-07. PMID:24828513. |
in contrast, aqp1 did not colocalize with gfap, an astrocyte marker, at any level of the spinal cord. |
2017-09-07 |
2023-08-13 |
rat |
| Hanzhang Liu, Wei Ji, Peipei Gong, Chun Liu, Chengwei Duan, Yilu Gao, Xiaojuan Liu, Dongmei Zhang, Shunxing Zhu, Leilei Gon. Spatiotemporal Patterns of RING1 Expression after Rat Spinal Cord Injury. Neurochemical research. vol 42. issue 4. 2017-08-04. PMID:28032293. |
furthermore, increased co-expression of ring1 and gfap confirmed activated astrocytes in injured spinal cord via double immunofluorescence staining. |
2017-08-04 |
2023-08-13 |
rat |
| Sergio M Borghi, Felipe A Pinho-Ribeiro, Victor Fattori, Allan J C Bussmann, Josiane A Vignoli, Doumit Camilios-Neto, Rubia Casagrande, Waldiceu A Verr. Quercetin Inhibits Peripheral and Spinal Cord Nociceptive Mechanisms to Reduce Intense Acute Swimming-Induced Muscle Pain in Mice. PloS one. vol 11. issue 9. 2017-08-02. PMID:27583449. |
beyond inhibiting those peripheral effects, quercetin also inhibited spinal cord cytokine production, oxidative stress and glial cells activation (glial fibrillary acidic protein [gfap] and ionized calcium-binding adapter molecule 1 [iba-1] mrna expression). |
2017-08-02 |
2023-08-13 |
mouse |
| Hannah R Wardill, Rachel J Gibson, Ysabella Z A Van Sebille, Kate R Secombe, Janet K Coller, Imogen A White, Jim Manavis, Mark R Hutchinson, Vasiliki Staikopoulos, Richard M Logan, Joanne M Bowe. Irinotecan-Induced Gastrointestinal Dysfunction and Pain Are Mediated by Common TLR4-Dependent Mechanisms. Molecular cancer therapeutics. vol 15. issue 6. 2017-06-27. PMID:27197307. |
gfap staining in the lumbar spinal cord, indicative of astrocytic activation, was increased at 6 and 72 hours in wt mice compared with balb/c-tlr4(-/-billy) mice (p = 0.008, p = 0.01). |
2017-06-27 |
2023-08-13 |
mouse |
| Vivien J Coulson-Thomas, Mark E Lauer, Sara Soleman, Chao Zhao, Vincent C Hascall, Anthony J Day, James W Fawcet. Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Is Constitutively Expressed in Adult Central Nervous System (CNS) and Associated with Astrocyte-mediated Glial Scar Formation following Spinal Cord Injury. The Journal of biological chemistry. vol 291. issue 38. 2017-05-19. PMID:27435674. |
we show that tsg-6 is expressed in the rat cns by gfap(+) and cd44(+) astrocytes, solely in the mature brain and spinal cord, and is not present during the development of the cns. |
2017-05-19 |
2023-08-13 |
mouse |
| Ryuji Terayama, Yuya Yamamoto, Noriko Kishimoto, Mitsuyasu Tabata, Kotaro Maruhama, Seiji Iida, Tomosada Sugimot. Differential Changes in Neuronal Excitability in the Spinal Dorsal Horn After Spinal Nerve Ligation in Rats. Neurochemical research. vol 41. issue 11. 2017-04-05. PMID:27418277. |
immunofluorescence labeling of ox-42 and gfap was also performed in histological sections of the spinal cord. |
2017-04-05 |
2023-08-13 |
rat |