| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexander E Ropper, Xiang Zeng, Jamie E Anderson, Dou Yu, InBo Han, Hariprakash Haragopal, Yang D Ten. An efficient device to experimentally model compression injury of mammalian spinal cord. Experimental neurology. vol 271. 2015-12-22. PMID:26210871. |
importantly, there are significantly increased gfap and app expressions in spinal cord segments involved in eliciting post-sci allodynia. |
2015-12-22 |
2023-08-13 |
rat |
| Jaime L Watson, Tamara J Hala, Rajarshi Putatunda, Daniel Sannie, Angelo C Lepor. Persistent at-level thermal hyperalgesia and tactile allodynia accompany chronic neuronal and astrocyte activation in superficial dorsal horn following mouse cervical contusion spinal cord injury. PloS one. vol 9. issue 9. 2015-12-21. PMID:25268642. |
following injury, an increase in the number of neurons expressing Δfosb (a marker of chronic neuronal activation), persistent astrocyte activation and proliferation (as measured by gfap and ki67 expression), and a decrease in the expression of the astrocyte glutamate transporter glt1 are observed in the ipsilateral superficial dorsal horn of cervical spinal cord. |
2015-12-21 |
2023-08-13 |
mouse |
| Saïd M'Dahoma, Sylvie Bourgoin, Valérie Kayser, Sandrine Barthélémy, Caroline Chevarin, Farah Chali, Didier Orsal, Michel Hamo. Spinal cord transection-induced allodynia in rats--behavioral, physiopathological and pharmacological characterization. PloS one. vol 9. issue 7. 2015-11-17. PMID:25019623. |
a marked up-regulation of mrnas encoding atf3 (neuronal injury) and glial activation markers (ox-42, gfap, p2×4, p2×7, tlr4) was observed in spinal cord and/or dorsal root ganglia at t6-t11 levels from day 2 up to day 60 post surgery. |
2015-11-17 |
2023-08-13 |
rat |
| Leslie A Hammer, Ian S Zagon, Patricia J McLaughli. Improved clinical behavior of established relapsing-remitting experimental autoimmune encephalomyelitis following treatment with endogenous opioids: implications for the treatment of multiple sclerosis. Brain research bulletin. vol 112. 2015-11-17. PMID:25647234. |
neuropathological examination of lumbar spinal cord after 40 days of treatment revealed decreased numbers of iba-1 and cd3+ reactive cells, suggesting that ogf inhibited proliferation of microglia/macrophages and t lymphocytes, as well as decreasing the number of proliferating activated astrocytes (ki-67 and gfap dual labeled sections). |
2015-11-17 |
2023-08-13 |
mouse |
| Magdalena Zychowska, Ewelina Rojewska, Wioletta Makuch, Barbara Przewlocka, Joanna Mik. The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain. European journal of pharmacology. vol 749. 2015-11-16. PMID:25460025. |
our studies examined the neuropathic pain-relieving properties after intraperitoneal injection of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine 7 days after sciatic nerve injury (cci) in rats and its influence on microglia/macrophages (iba-1) and astroglia (gfap) activation in the spinal cord and dorsal root ganglia (drg) using western blot. |
2015-11-16 |
2023-08-13 |
rat |
| Tadasu Sato, Masatoshi Fujita, Yoshinaka Shimizu, Hiroyasu Kanetaka, Leona W G Chu, Patrice D Côté, Hiroyuki Ichikaw. Glial reaction in the spinal cord of the degenerating muscle mouse (Scn8a (dmu)). Neurochemical research. vol 40. issue 1. 2015-11-10. PMID:25380697. |
glial fibrillary acidic protein (gfap)- and iba1-immunoreactivity were detected in numerous cells throughout the spinal cord of wild type mice. |
2015-11-10 |
2023-08-13 |
mouse |
| Frederika Maria Byrne, Sharon Cheetham, Steven Vickers, Victoria Chapma. Characterisation of pain responses in the high fat diet/streptozotocin model of diabetes and the analgesic effects of antidiabetic treatments. Journal of diabetes research. vol 2015. 2015-10-29. PMID:25759824. |
hfd/stz rats had significantly lower numbers of spinal iba-1 positive cells (morphologically identified as activated microglia) and spinal gfap immunofluorescence (a marker of astrogliosis) in the spinal cord at day 50, compared to time-matched controls. |
2015-10-29 |
2023-08-13 |
rat |
| Tian-Zun Li, Yi Yan, Qiang Liu, Yong-Zhi Xi. [Effect of suppressing apoptosis signal regulating kinase 1 on GFAP and vimentin expression and hindlimb mobility in rats after spinal cord injury]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 35. issue 6. 2015-09-25. PMID:26111673. |
[effect of suppressing apoptosis signal regulating kinase 1 on gfap and vimentin expression and hindlimb mobility in rats after spinal cord injury]. |
2015-09-25 |
2023-08-13 |
rat |
| Tian-Zun Li, Yi Yan, Qiang Liu, Yong-Zhi Xi. [Effect of suppressing apoptosis signal regulating kinase 1 on GFAP and vimentin expression and hindlimb mobility in rats after spinal cord injury]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 35. issue 6. 2015-09-25. PMID:26111673. |
to investigate the effect of suppressing apoptosis signal regulating kinase 1 (ask1) on glial fibrillary acidic protein (gfap) and vimentin expressions at the injury site and on hindlimb mobility in rats after spinal cord injury (sci). |
2015-09-25 |
2023-08-13 |
rat |
| J Juhasova, S Juhas, M Hruska-Plochan, D Dolezalova, M Holubova, J Strnadel, S Marsala, J Motlik, M Marsal. Time course of spinal doublecortin expression in developing rat and porcine spinal cord: implication in in vivo neural precursor grafting studies. Cellular and molecular neurobiology. vol 35. issue 1. 2015-09-14. PMID:25487013. |
in addition, complementary temporospatial gfap expression study in porcine spinal cord was also performed. |
2015-09-14 |
2023-08-13 |
human |
| Yan-Mei Yin, Yu Lu, Li-Xin Zhang, Guang-Ping Zhang, Zhi-Qiang Zhan. Bone marrow stromal cells transplantation combined with ultrashortwave therapy promotes functional recovery on spinal cord injury in rats. Synapse (New York, N.Y.). vol 69. issue 3. 2015-09-10. PMID:25600592. |
bmscs + usw rats had a lower ratio of lesion/cavity to spinal cord area than the other injured rats, and also had expression of gfap in transplanted bmscs. |
2015-09-10 |
2023-08-13 |
rat |
| Haitao Sun, Zongliu Hou, Huaqiang Yang, Mingyao Meng, Peng Li, Qingjian Zou, Lujun Yang, Yuxin Chen, Huihui Chai, Huilin Zhong, Zara Zhuyun Yang, Jing Zhao, Liangxue Lai, Xiaodan Jiang, Zhicheng Xia. Multiple systemic transplantations of human amniotic mesenchymal stem cells exert therapeutic effects in an ALS mouse model. Cell and tissue research. vol 357. issue 3. 2015-09-01. PMID:24906288. |
hamscs were detected in the spinal cord at the final stage of the disease, in the form of isolates or clusters and were negative for β-tubulin iii and gfap. |
2015-09-01 |
2023-08-13 |
mouse |
| Jianing Zu, Yufu Wang, Gongping Xu, Jinpeng Zhuang, He Gong, Jinglong Ya. Curcumin improves the recovery of motor function and reduces spinal cord edema in a rat acute spinal cord injury model by inhibiting the JAK/STAT signaling pathway. Acta histochemica. vol 116. issue 8. 2015-08-20. PMID:25201116. |
in conclusion, our data demonstrate that curcumin exhibits a moderately protective effect on spinal cord injury, and this effect might be related to the inhibition of overexpressed aqp4 and gfap and the activated jak/stat signaling pathway. |
2015-08-20 |
2023-08-13 |
human |
| Chih-Yen Wang, Shang-Hsun Yang, Shun-Fen Tzen. MicroRNA-145 as one negative regulator of astrogliosis. Glia. vol 63. issue 2. 2015-08-19. PMID:25139829. |
to induce overexpression of mir-145 in astrocytes at the spinal cord lesion site, we developed a lentivirus-mediated pre-mirna delivery system using the promoter of glial fibrillary acidic protein (gfap), an astrocyte-specific intermediate filament. |
2015-08-19 |
2023-08-13 |
rat |
| Marzieh Darvishi, Taki Tiraihi, Seyed A Mesbah-Namin, AliReza Delshad, Taher Taher. Decreased GFAP expression and improved functional recovery in contused spinal cord of rats following valproic acid therapy. Neurochemical research. vol 39. issue 12. 2015-08-04. PMID:25205382. |
decreased gfap expression and improved functional recovery in contused spinal cord of rats following valproic acid therapy. |
2015-08-04 |
2023-08-13 |
rat |
| Wenzhan Tu, Wansheng Wang, Haiyan Xi, Rong He, Liping Gao, Songhe Jian. Regulation of Neurotrophin-3 and Interleukin-1β and Inhibition of Spinal Glial Activation Contribute to the Analgesic Effect of Electroacupuncture in Chronic Neuropathic Pain States of Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-07-10. PMID:26161124. |
we used immunofluorescence and western blots methods to investigate the effect of ea on the expression of nt-3 and il-1β in drg and spinal cord of cci rats; we also examined the expression of spinal gfap and ox-42 in spinal cord. |
2015-07-10 |
2023-08-13 |
rat |
| Mathieu Desclaux, Florence E Perrin, Anh Do-Thi, Monica Prieto-Cappellini, Minerva Gimenez Y Ribotta, Jacques Mallet, Alain Priva. Lentiviral-mediated silencing of glial fibrillary acidic protein and vimentin promotes anatomical plasticity and functional recovery after spinal cord injury. Journal of neuroscience research. vol 93. issue 1. 2015-07-08. PMID:25131829. |
to promote regeneration and sprouting of spared axons after spinal cord trauma and with the objective of translation to clinics, we designed an original in vivo gene transfer strategy to reduce glial scar formation after sci, based on the rna interference (rnai)-mediated inhibition of gfap and vim. |
2015-07-08 |
2023-08-13 |
mouse |
| Saeed Esmaeili-Mahani, Bahareh Ebrahimi, Mehdi Abbasnejad, Bahram Rasoulian, Vahid Sheiban. Satureja khuzestanica prevents the development of morphine analgesic tolerance through suppression of spinal glial cell activation in rats. Journal of natural medicines. vol 69. issue 2. 2015-06-02. PMID:23943205. |
the lumbar spinal cord was assayed to determine glial fibrillary acidic protein (gfap) and tumor necrosis factor alpha (tnfα) levels by the western blotting method. |
2015-06-02 |
2023-08-12 |
rat |
| Saeed Esmaeili-Mahani, Bahareh Ebrahimi, Mehdi Abbasnejad, Bahram Rasoulian, Vahid Sheiban. Satureja khuzestanica prevents the development of morphine analgesic tolerance through suppression of spinal glial cell activation in rats. Journal of natural medicines. vol 69. issue 2. 2015-06-02. PMID:23943205. |
in tolerant animals, a significant increase in gfap and tnfα levels was observed in the lumbar spinal cord, and was reversed to control levels by 100 mg/kg ske. |
2015-06-02 |
2023-08-12 |
rat |
| Yoshihiro Kuga, Hideki Ohnishi, Yuji Kodama, Shuji Takakura, Masato Hayashi, Ryokichi Yagi, Kenji Fukutome, Ken Matsushima, Kouichirou Okamoto, Katsushi Taomoto, Hitoshi Takahash. Cerebral and spinal cord tanycytic ependymomas in a young adult with a mutation in the NF2 gene. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 34. issue 4. 2015-05-11. PMID:24612193. |
immunohistochemical and ultrastructural observations revealed that all the tumors were ependymal in nature with positivity for gfap and epithelial membrane antigen and negativity for oligodendrocyte transcription factor 2, showing intra- and intercellular microrosettes, leading us to a diagnosis of tanycytic ependymoma for the frontal lobe tumor and tanycytic ependymoma with ordinary ependymomatous component for the spinal cord tumors. |
2015-05-11 |
2023-08-12 |
Not clear |