| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yun Wang, Chun-Feng Liu, Qi-Ping Wang, Heng Gao, Han-Rong Na, Ru-Tong Y. Establishment of a spinal cord injury model in adult rats by an electrocircuit-controlled impacting device and its pathological observations. Cell biochemistry and biophysics. vol 69. issue 2. 2014-12-24. PMID:24338564. |
the changes of nse, nf, and gfap after spinal cord injury reflect the characteristics of pathological change, which are closely associated with the functional recovery from the spinal cord injury. |
2014-12-24 |
2023-08-12 |
rat |
| Cuicui Wang, Xiaohong Liu, Ruiqi Mao, Yongcheng Cao, Liquan Bi, Ming Gen. [Changes in levels of TNF-α and GFAP in brain and spinal cord of rabbits with decompression disease]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. vol 32. issue 8. 2014-12-22. PMID:25182994. |
[changes in levels of tnf-α and gfap in brain and spinal cord of rabbits with decompression disease]. |
2014-12-22 |
2023-08-13 |
Not clear |
| Jenny Schreiber, Melitta Schachner, Udo Schumacher, Dietrich Ernst Lork. Extracellular matrix alterations, accelerated leukocyte infiltration and enhanced axonal sprouting after spinal cord hemisection in tenascin-C-deficient mice. Acta histochemica. vol 115. issue 8. 2014-12-05. PMID:23701962. |
one, three, seven and fourteen days post-surgery, cryostat sections of the spinal cord were examined by conventional histology and by immunohistochemistry using antibodies against f4/80 (microglia/macrophage), gfap (astroglia), neurofilament, fibronectin, laminin and collagen type iv. |
2014-12-05 |
2023-08-12 |
mouse |
| Chuanyin Hu, Guoping Zhang, Yun-Tao Zha. Fucoidan attenuates the existing allodynia and hyperalgesia in a rat model of neuropathic pain. Neuroscience letters. vol 571. 2014-12-03. PMID:24792391. |
glial activation markers such as glial fibrillary acidic protein (gfap) and macrophage antigen complex-1 (mac-1), inflammatory cytokines such as tumor necrosis factor (tnf)-α, interleukin (il)-1β and il-6 activation, and extracellular signalregulated protein kinase (erk) activation in the lumbar spinal cord were determined on day 30 after operation. |
2014-12-03 |
2023-08-13 |
rat |
| Bao-ling Du, Chen-guang Zeng, Wei Zhang, Da-ping Quan, Eng-ang Ling, Yuan-shan Zen. A comparative study of gelatin sponge scaffolds and PLGA scaffolds transplanted to completely transected spinal cord of rat. Journal of biomedical materials research. Part A. vol 102. issue 6. 2014-12-01. PMID:23776140. |
western blot showed asic1a and gfap expression of injured spinal cord was downregulated in the gs group. |
2014-12-01 |
2023-08-12 |
rat |
| Qian Xu, Yong-Kwan Cheong, Shao-Qiu He, Vinod Tiwari, Jian Liu, Yun Wang, Srinivasa N Raja, Jinheng Li, Yun Guan, Weiyan L. Suppression of spinal connexin 43 expression attenuates mechanical hypersensitivity in rats after an L5 spinal nerve injury. Neuroscience letters. vol 566. 2014-11-11. PMID:24631560. |
furthermore, western blot analysis showed that the pain inhibition induced by cx43 sirna correlated with downregulation of cx43 expression, but not that of cx36 (the neuronal gap junction protein) or glial fibrillary acidic protein (gfap, a marker for reactive astrocytes) in the spinal cord of snl rats. |
2014-11-11 |
2023-08-12 |
rat |
| Qian Xu, Yong-Kwan Cheong, Shao-Qiu He, Vinod Tiwari, Jian Liu, Yun Wang, Srinivasa N Raja, Jinheng Li, Yun Guan, Weiyan L. Suppression of spinal connexin 43 expression attenuates mechanical hypersensitivity in rats after an L5 spinal nerve injury. Neuroscience letters. vol 566. 2014-11-11. PMID:24631560. |
western blot analysis and immunohistochemistry also showed that snl increased gfap expression, but decreased cx43 expression, in spinal cord. |
2014-11-11 |
2023-08-12 |
rat |
| Marta Pevida, Sara González-Rodríguez, Ana Lastra, Olivia García-Suárez, Agustín Hidalgo, Luis Menéndez, Ana Baamond. Involvement of spinal chemokine CCL2 in the hyperalgesia evoked by bone cancer in mice: a role for astroglia and microglia. Cellular and molecular neurobiology. vol 34. issue 1. 2014-09-28. PMID:24122510. |
in contrast, immunohistochemical assays demonstrated the spinal up-regulations of gfap and iba-1, respective markers of astroglia and microglia, and the expression of ccl2 in both types of glial cells at the superficial laminae of the spinal cord of tumor-bearing mice. |
2014-09-28 |
2023-08-12 |
mouse |
| Lan Li, Zhi-yong Xiong, Zhong Ming Qian, Tian-zhi Zhao, Hua Feng, Sengli Hu, Rong Hu, Ya Ke, Jiangkai Li. Complement C5a is detrimental to histological and functional locomotor recovery after spinal cord injury in mice. Neurobiology of disease. vol 66. 2014-09-24. PMID:24607885. |
furthermore, c5ara mice and c5ar-/- mice had less gfap expression in the injured spinal cord epicenter as compared to saline mice and c5ar+/+ mice at day 28 after sci. |
2014-09-24 |
2023-08-12 |
mouse |
| Dong Liu, Chaoxu Liu, Junqiang Li, Kazem Azadzoi, Yun Yang, Zhou Fei, Kefeng Dou, Neil W Kowall, Han-Pil Choi, Fernando Vieira, Jing-Hua Yan. Proteomic analysis reveals differentially regulated protein acetylation in human amyotrophic lateral sclerosis spinal cord. PloS one. vol 8. issue 12. 2014-08-18. PMID:24312501. |
immunoprecipitation followed by western blotting confirms that the larger form of gfap fragments are acetylated and upregulated in als spinal cord. |
2014-08-18 |
2023-08-12 |
human |
| Roberto Fiorelli, Arantxa Cebrian-Silla, Jose-Manuel Garcia-Verdugo, Olivier Rainetea. The adult spinal cord harbors a population of GFAP-positive progenitors with limited self-renewal potential. Glia. vol 61. issue 12. 2014-06-20. PMID:24123239. |
we demonstrate that a population of gfap(+) cells that share the morphology and the antigenic properties of svz-nscs mostly reside in the dorsal aspect of the central canal (cc) throughout the spinal cord. |
2014-06-20 |
2023-08-12 |
mouse |
| Dae-Hyun Roh, Min-Soo Seo, Hoon-Seong Choi, Sang-Bum Park, Ho-Jae Han, Alvin J Beitz, Kyung-Sun Kang, Jang-Hern Le. Transplantation of human umbilical cord blood or amniotic epithelial stem cells alleviates mechanical allodynia after spinal cord injury in rats. Cell transplantation. vol 22. issue 9. 2014-06-09. PMID:23294734. |
both hucb-mscs and haescs reduced the sci-induced increase in spinal cord expression of the microglial marker, f4/80, but not the increased expression of gfap or inos. |
2014-06-09 |
2023-08-12 |
human |
| Fen Liu, Yu Zou, Sujuan Liu, Jia Liu, Tinghua Wan. Electro-acupuncture treatment improves neurological function associated with downregulation of PDGF and inhibition of astrogliosis in rats with spinal cord transection. Journal of molecular neuroscience : MN. vol 51. issue 2. 2014-05-30. PMID:23749676. |
ea treatment not only decreased effectively the number of gfap immunostaining and gfap expression, but also downregulated the pdgf expression both gene and protein, in addition decreased the number of pdgf immunostaining in injured spinal cord of rats with transection. |
2014-05-30 |
2023-08-12 |
rat |
| Ying Ding, Qing Yan, Jing-Wen Ruan, Yan-Qing Zhang, Wen-Jie Li, Xiang Zeng, Si-Fan Huang, Yu-Jiao Zhang, Jin-Lang Wu, Danny Fisher, Hongxin Dong, Yuan-Shan Zen. Electroacupuncture promotes the differentiation of transplanted bone marrow mesenchymal stem cells overexpressing TrkC into neuron-like cells in transected spinal cord of rats. Cell transplantation. vol 22. issue 1. 2014-04-08. PMID:23006476. |
in the trkc-mscs + ea group, the injured spinal cord also showed upregulated expression of the proneurogenic factors laminin and gap-43 and downregulated gfap and chondroitin sulfate proteoglycans (cspgs), major inhibitors of axonal growth. |
2014-04-08 |
2023-08-12 |
rat |
| Ying Ding, Qing Yan, Jing-Wen Ruan, Yan-Qing Zhang, Wen-Jie Li, Xiang Zeng, Si-Fan Huang, Yu-Jiao Zhang, Jin-Lang Wu, Danny Fisher, Hongxin Dong, Yuan-Shan Zen. Electroacupuncture promotes the differentiation of transplanted bone marrow mesenchymal stem cells overexpressing TrkC into neuron-like cells in transected spinal cord of rats. Cell transplantation. vol 22. issue 1. 2014-04-08. PMID:23006476. |
together, our data suggest that trkc-msc transplantation combined with ea treatment spinal cord injury not only increased msc survival and differentiation into neuron-like cells but also promoted cst regeneration across injured sites to the caudal cord and functional improvement, perhaps due to increase of nt-3 levels, upregulation of laminin and gap-43, and downregulation of gfap and cspg proteins. |
2014-04-08 |
2023-08-12 |
rat |
| Nilesh K Mitra, Tiffanie E W Goh, Thalisha Bala Krishnan, Vishna D Nadarajah, Arun K Vasavaraj, Tomoko Sog. Effect of intra-cisternal application of kainic acid on the spinal cord and locomotor activity in rats. International journal of clinical and experimental pathology. vol 6. issue 8. 2014-03-21. PMID:23923068. |
gfap expression increased significantly in the lumbar section of the spinal cord with high dose of ka treatment (p<0.05). |
2014-03-21 |
2023-08-12 |
rat |
| T Berta, Y-C Liu, Z-Z Xu, R-R J. Tissue plasminogen activator contributes to morphine tolerance and induces mechanical allodynia via astrocytic IL-1β and ERK signaling in the spinal cord of mice. Neuroscience. vol 247. 2014-03-18. PMID:23707980. |
chronic morphine induces tpa expression in glial fibrillary acidic protein (gfap)-expressing spinal cord astrocytes. |
2014-03-18 |
2023-08-12 |
mouse |
| Rui Ge, Yue Zhu, Yao Diao, Lin Tao, Wei Yuan, Xiao-chuan Xion. Anti-edema effect of epigallocatechin gallate on spinal cord injury in rats. Brain research. vol 1527. 2014-03-14. PMID:23831998. |
the changes of aqp4 and gfap protein induced by egcg (100 mg/kg) treatment were accompanied by a reduction of spinal cord edema. |
2014-03-14 |
2023-08-12 |
rat |
| Rui Ge, Yue Zhu, Yao Diao, Lin Tao, Wei Yuan, Xiao-chuan Xion. Anti-edema effect of epigallocatechin gallate on spinal cord injury in rats. Brain research. vol 1527. 2014-03-14. PMID:23831998. |
our results indicated that egcg (100 mg/kg) could reduce spinal cord edema after sci, which could be correlated with the down-regulation the expression of aqp4 and gfap protein level after sci. |
2014-03-14 |
2023-08-12 |
rat |
| Xu Tao, Yang Ming-Kun, Sheng Wei-Bin, Guo Hai-Long, Kan Rui, Tu Lai-Yon. Role of telomerase reverse transcriptase in glial scar formation after spinal cord injury in rats. Neurochemical research. vol 38. issue 9. 2014-03-10. PMID:23793903. |
immunofluorescence detection showed a significant increase in gfap expression at all time points after spinal cord injury in the sci only group (81 %) compared with the tert sirna group (67 %) and sham group (2 %). |
2014-03-10 |
2023-08-12 |
rat |