| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Irena Baranowska-Bosiacka, Joanna Listos, Izabela Gutowska, Anna Machoy-Mokrzyńska, Agnieszka Kolasa-Wołosiuk, Maciej Tarnowski, Kamila Puchałowicz, Adam Prokopowicz, Sylwia Talarek, Piotr Listos, Agnieszka Wąsik, Dariusz Chlube. Effects of perinatal exposure to lead (Pb) on purine receptor expression in the brain and gliosis in rats tolerant to morphine analgesia. Toxicology. vol 339. 2016-05-23. PMID:26478469. |
the analysis revealed a significant up-regulation of protein and mrna p2x4 receptor expression in the striatum and prefrontal cortex but not in the hippocampus; p2x7 protein and mrna receptor expression in the striatum and hippocampus, but not in the prefrontal cortex; a1 protein receptor expression in all investigated structures and a1 mrna expression in the striatum and hippocampus; iba1 mrna expression in the striatum and hippocampus; and gfap mrna expression in the striatum and prefrontal cortex. |
2016-05-23 |
2023-08-13 |
rat |
| Xian-Jian Huang, Olena Glushakova, Stefania Mondello, Ken Van, Ronald L Hayes, Bruce G Lyet. Acute Temporal Profiles of Serum Levels of UCH-L1 and GFAP and Relationships to Neuronal and Astroglial Pathology following Traumatic Brain Injury in Rats. Journal of neurotrauma. vol 32. issue 16. 2016-05-06. PMID:25763798. |
histology revealed characteristic acute neuronal degeneration in the ipsilateral hippocampus and parietal cortex and reduction in gfap immunostaining in areas of neuronal cell loss. |
2016-05-06 |
2023-08-13 |
rat |
| Hyung-Mun Yun, Jin A Kim, Chul Ju Hwang, Peng Jin, Myung Ki Baek, Jin Moo Lee, Ji Eun Hong, Sang Min Lee, Sang Bae Han, Ki Wan Oh, Dong Young Choi, Do Young Yoon, Jin Tae Hon. Neuroinflammatory and Amyloidogenic Activities of IL-32β in Alzheimer's Disease. Molecular neurobiology. vol 52. issue 1. 2016-05-02. PMID:25159479. |
the expression of glial fibrillary acid protein (gfap), iba1, and β-secretase 1 (bace1) in the cortex and hippocampus was much higher in the aβ1-42-infused il-32β tg mice brain. |
2016-05-02 |
2023-08-13 |
mouse |
| Rubén García-Cabrerizo, M Julia García-Fuste. Chronic MDMA induces neurochemical changes in the hippocampus of adolescent and young adult rats: Down-regulation of apoptotic markers. Neurotoxicology. vol 49. 2016-04-25. PMID:26068050. |
the data, together with the observed lack of gfap activation, support the view that chronic mdma effects, regardless of the rat developmental age, extends beyond neurotransmitter systems to impair other hippocampal structural cell markers. |
2016-04-25 |
2023-08-13 |
rat |
| Benjamin Keller, Jesús A García-Sevill. Regulation of hippocampal Fas receptor and death-inducing signaling complex after kainic acid treatment in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 63. 2016-04-08. PMID:26044520. |
ka (45mg/kg) induced a severe behavioral syndrome with recurrent motor seizures (scores; maximal at 60-90min; minimal at 72h) with activation of hippocampal pro-apoptotic jnk (+2.5 fold) and increased gfap (+57%) and nuclear parp-1 fragmentation (+114%) 72h post-treatment (delayed neurotoxicity). |
2016-04-08 |
2023-08-13 |
mouse |
| Martín Gabriel Codagnone, María Fernanda Podestá, Nonthué Alejandra Uccelli, Analía Reiné. Differential Local Connectivity and Neuroinflammation Profiles in the Medial Prefrontal Cortex and Hippocampus in the Valproic Acid Rat Model of Autism. Developmental neuroscience. vol 37. issue 3. 2016-03-29. PMID:25895486. |
neuronal alterations were accompanied with increased tomato lectin and glial fibrillary acidic protein (gfap) immunostainings both in the mpfc and hippocampus. |
2016-03-29 |
2023-08-13 |
rat |
| Felipe V Gomes, Ricardo Llorente, Elaine A Del Bel, Maria-Paz Viveros, Meritxell López-Gallardo, Francisco S Guimarãe. Decreased glial reactivity could be involved in the antipsychotic-like effect of cannabidiol. Schizophrenia research. vol 164. issue 1-3. 2016-03-28. PMID:25680767. |
we also evaluated changes in neun (a neuronal marker), iba-1 (a microglia marker) and gfap (an astrocyte marker) expression in the medial prefrontal cortex (mpfc), dorsal striatum, nucleus accumbens core and shell, and dorsal hippocampus by immunohistochemistry. |
2016-03-28 |
2023-08-13 |
Not clear |
| Florencia M Bercum, Krista M Rodgers, Alex M Benison, Zachariah Z Smith, Jeremy Taylor, Elise Kornreich, Heidi L Grabenstatter, F Edward Dudek, Daniel S Bart. Maternal Stress Combined with Terbutaline Leads to Comorbid Autistic-Like Behavior and Epilepsy in a Rat Model. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 48. 2016-03-28. PMID:26631470. |
hippocampal gliosis (gfap reactivity) was correlated with both abnormal behavior and spontaneous seizures. |
2016-03-28 |
2023-08-13 |
human |
| Huai-bin Li, Feng Wu, Ke-ren Xiong, Hua-chun Miao, Xiu-ling Zh. [Effects of Electroacupuncture Intervention Combined with Gastrodin on Expression of Proteins Related to Proliferation-differentiation of Neural Stem Cells in Hippocampal CA 1 and CA 3 Regions in Focal Cerebral Ischemia Rats]. Zhen ci yan jiu = Acupuncture research. vol 40. issue 6. 2016-03-10. PMID:26887206. |
to observe the effect of electroacupuncture(ea) combined with medication on changes of expression of nestin, glial fibrillary acidic protein (gfap) and neuron specific enolase (nse) in the hippocampal ca 1 and ca 3 regions of focal cerebral ischemia (fc1) rats, so as to analyze its mechanisms underlying neuroprotection. |
2016-03-10 |
2023-08-13 |
rat |
| Bo Zhang, Jia Zou, Nicholas R Rensing, Meihua Yang, Michael Won. Inflammatory mechanisms contribute to the neurological manifestations of tuberous sclerosis complex. Neurobiology of disease. vol 80. 2016-02-29. PMID:26003087. |
real-time quantitative rt-pcr, immunohistochemistry, and western blotting demonstrated increased expression of specific cytokines and chemokines, particularly il-1β and cxcl10, in the neocortex and hippocampus of tsc1(gfap)cko mice, which was reversed by treatment with a mammalian target of rapamycin complex 1 (mtorc1) inhibitor. |
2016-02-29 |
2023-08-13 |
mouse |
| Sónia Sá Santos, Sara M Santos, Antónia R T Pinto, Vasanthakumar G Ramu, Montserrat Heras, Eduard Bardaji, Isaura Tavares, Miguel A R B Castanh. Amidated and Ibuprofen-Conjugated Kyotorphins Promote Neuronal Rescue and Memory Recovery in Cerebral Hypoperfusion Dementia Model. Frontiers in aging neuroscience. vol 8. 2016-02-09. PMID:26858637. |
after behavioral testing (week 6), coronal sections of hippocampus were h&e-stained or immunolabeled for the cellular markers gfap (astrocytes) and nfl (neurons). |
2016-02-09 |
2023-08-13 |
rat |
| Petra Sántha, Szilvia Veszelka, Zsófia Hoyk, Mária Mészáros, Fruzsina R Walter, Andrea E Tóth, Lóránd Kiss, András Kincses, Zita Oláh, György Seprényi, Gábor Rákhely, András Dér, Magdolna Pákáski, János Kálmán, Ágnes Kittel, Mária A Del. Restraint Stress-Induced Morphological Changes at the Blood-Brain Barrier in Adult Rats. Frontiers in molecular neuroscience. vol 8. 2016-02-02. PMID:26834555. |
frontal cortex and hippocampus sections were immunostained for markers of brain endothelial cells (claudin-5, occluding, and glucose transporter-1) and astroglia (gfap). |
2016-02-02 |
2023-08-13 |
rat |
| N Li, X Liu, P Zhang, M Qiao, H Li, X Li, H Zhang, Z Y. The effects of early life lead exposure on the expression of interleukin (IL) 1β, IL-6, and glial fibrillary acidic protein in the hippocampus of mouse pups. Human & experimental toxicology. vol 34. issue 4. 2016-01-29. PMID:25028260. |
the present study was undertaken to investigate the effects of maternal lead (pb) exposure on the expression of interleukin (il) 1β, il 6, and glial fibrillary acidic protein (gfap) in hippocampus of mice offspring. |
2016-01-29 |
2023-08-13 |
mouse |
| N Li, X Liu, P Zhang, M Qiao, H Li, X Li, H Zhang, Z Y. The effects of early life lead exposure on the expression of interleukin (IL) 1β, IL-6, and glial fibrillary acidic protein in the hippocampus of mouse pups. Human & experimental toxicology. vol 34. issue 4. 2016-01-29. PMID:25028260. |
the expression of il 1β, il 6, and gfap in hippocampus was measured by immunohistochemistry and western blotting. |
2016-01-29 |
2023-08-13 |
mouse |
| N Li, X Liu, P Zhang, M Qiao, H Li, X Li, H Zhang, Z Y. The effects of early life lead exposure on the expression of interleukin (IL) 1β, IL-6, and glial fibrillary acidic protein in the hippocampus of mouse pups. Human & experimental toxicology. vol 34. issue 4. 2016-01-29. PMID:25028260. |
the high expression of il-1β, il-6, and gfap in the hippocampus of pups may contribute to the neurotoxicity associated with maternal pb exposure. |
2016-01-29 |
2023-08-13 |
mouse |
| Isabell Lebkuechner, Ulrika Wilhelmsson, Elin Möllerström, Marcela Pekna, Milos Pekn. Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency. Journal of neurochemistry. vol 135. issue 2. 2016-01-11. PMID:26118771. |
here, we used real-time quantitative pcr to analyze gene expression in individual mouse astrocytes in primary cultures and in gfap(pos) or aldh1l1(pos) astrocytes freshly isolated from uninjured, contralesional and lesioned hippocampus 4 days after entorhinal cortex lesion. |
2016-01-11 |
2023-08-13 |
mouse |
| Daniela F de Souza, Krista M Wartchow, Paula S Lunardi, Giovana Brolese, Lucas S Tortorelli, Cristiane Batassini, Regina Biasibetti, Carlos-Alberto Gonçalve. Changes in Astroglial Markers in a Maternal Immune Activation Model of Schizophrenia in Wistar Rats are Dependent on Sex. Frontiers in cellular neuroscience. vol 9. 2016-01-06. PMID:26733814. |
moreover, we also found augmented gfap in the frontal cortex of the lps group at pnd 30, but not in the hippocampus. |
2016-01-06 |
2023-08-13 |
rat |
| Hyeonwi Son, Soonwoong Jung, Jun Young Kim, Young Min Goo, Kye Man Cho, Dong Hoon Lee, Gu Seob Roh, Sang Soo Kang, Gyeong Jae Cho, Wan Sung Choi, Hyun Joon Ki. Type 1 diabetes alters astrocytic properties related with neurotransmitter supply, causing abnormal neuronal activities. Brain research. vol 1602. 2015-12-14. PMID:25578257. |
in t1d mouse, gs expression increased in the prefrontal cortex (pfc) and hippocampus (hi), but decreased gs activity was only observed in the hi whereas gfap expression decreased in both regions. |
2015-12-14 |
2023-08-13 |
mouse |
| Judith M van der Harg, Leslie Eggels, Silvie R Ruigrok, Jeroen J M Hoozemans, Susanne E la Fleur, Wiep Schepe. Neuroinflammation is not a Prerequisite for Diabetes-induced Tau Phosphorylation. Frontiers in neuroscience. vol 9. 2015-11-30. PMID:26617484. |
remarkably, neither of the diabetic animal models showed reactive microglia or increased gfap and cox-2 levels in the cortex or hippocampus. |
2015-11-30 |
2023-08-13 |
rat |
| Sergio D Paredes, Lisa Rancan, Roman Kireev, Alberto González, Pedro Louzao, Pablo González, Cruz Rodríguez-Bobada, Cruz García, Elena Vara, Jesús A F Tresguerre. Melatonin Counteracts at a Transcriptional Level the Inflammatory and Apoptotic Response Secondary to Ischemic Brain Injury Induced by Middle Cerebral Artery Blockade in Aging Rats. BioResearch open access. vol 4. issue 1. 2015-11-23. PMID:26594596. |
hippocampal gfap was also significantly elevated, while bcl-2 and sirtuin 1 decreased significantly in response to ischemia. |
2015-11-23 |
2023-08-13 |
rat |