| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Núbia Broetto, Fernanda Hansen, Giovana Brolese, Cristiane Batassini, Franciane Lirio, Fabiana Galland, João Paulo Almeida Dos Santos, Márcio Ferreira Dutra, Carlos-Alberto Gonçalve. Intracerebroventricular administration of okadaic acid induces hippocampal glucose uptake dysfunction and tau phosphorylation. Brain research bulletin. vol 124. 2017-10-26. PMID:27108544. |
icv infusion of oka (at 200ng) induced a spatial cognitive deficit, hippocampal astrogliosis (based on gfap increment) and increase in tau phosphorylation at site 396 in this model. |
2017-10-26 |
2023-08-13 |
rat |
| Sindhu K Madathil, Shaun W Carlson, Jennifer M Brelsfoard, Ping Ye, A Joseph D'Ercole, Kathryn E Saatma. Astrocyte-Specific Overexpression of Insulin-Like Growth Factor-1 Protects Hippocampal Neurons and Reduces Behavioral Deficits following Traumatic Brain Injury in Mice. PloS one. vol 8. issue 6. 2017-10-17. PMID:23826235. |
following brain injury, igf-1tg mice exhibited a progressive increase in hippocampal igf-1 levels which was coupled with enhanced hippocampal reactive astrocytosis and significantly greater gfap levels relative to wt mice. |
2017-10-17 |
2023-08-12 |
mouse |
| b' Jo\\xc3\\xa3o Paulo Lopes Born, Heloisa de Carvalho Matos, Mykaella Andrade de Araujo, Olagide Wagner Castro, Marcelo Duzzioni, Jos\\xc3\\xa9 Eduardo Peixoto-Santos, Jo\\xc3\\xa3o Pereira Leite, Norberto Garcia-Cairasco, Maria Luisa Pa\\xc3\\xa7\\xc3\\xb3-Larson, Daniel Leite G\\xc3\\xb3es Gita\\xc3\\xa. Using Postmortem hippocampi tissue can interfere with differential gene expression analysis of the epileptogenic process. PloS one. vol 12. issue 8. 2017-10-06. PMID:28783762.' |
for this, we selected six genes (gfap, ppia, gad65, gad67, npy, and tnf-α) whose expression patterns in the hippocampus of pilo-injected rats are well known. |
2017-10-06 |
2023-08-13 |
rat |
| Nasra Naeim Ayuo. Evaluation of the antidepressant-like effect of musk in an animal model of depression: how it works. Anatomical science international. vol 92. issue 4. 2017-09-28. PMID:27444866. |
histopathological examination of the hippocampus and immunohistochemical techniques using glial fibrillary acidic protein (gfap), ki67, caspase-3, bdnf and gr were performed. |
2017-09-28 |
2023-08-13 |
mouse |
| Lin Chen, Xin Wang, Zi-Xuan Lin, Jian-Guo Dai, Yu-Fang Huang, Yu-Nan Zha. Preventive Effects of Ginseng Total Saponins on Chronic Corticosterone-Induced Impairment in Astrocyte Structural Plasticity and Hippocampal Atrophy. Phytotherapy research : PTR. vol 31. issue 9. 2017-09-25. PMID:28656606. |
at 6 h after the last dose of corticosterone (day 35), all mice were sacrificed followed by serum corticosterone assays, stereological analysis of hippocampal glial fibrillary acidic protein-positive (gfap |
2017-09-25 |
2023-08-13 |
mouse |
| M Martínez-Moreno, M Batlle, F J Ortega, J Gimeno-Bayón, C Andrade, N Mahy, M J Rodrígue. Diazoxide enhances excitotoxicity-induced neurogenesis and attenuates neurodegeneration in the rat non-neurogenic hippocampus. Neuroscience. vol 333. 2017-09-06. PMID:27471195. |
furthermore, glial fibrillary acidic protein (gfap)-positive cells in the injured hippocampus expressed transcription factor sp8 indicating that the excitotoxic lesion elicited the migration of progenitors from the subventricular zone and/or the reprograming of reactive astrocytes. |
2017-09-06 |
2023-08-13 |
rat |
| Nelson Perez-Urrutia, Cristhian Mendoza, Nathalie Alvarez-Ricartes, Patricia Oliveros-Matus, Florencia Echeverria, J Alex Grizzell, George E Barreto, Alexandre Iarkov, Valentina Echeverri. Intranasal cotinine improves memory, and reduces depressive-like behavior, and GFAP+ cells loss induced by restraint stress in mice. Experimental neurology. vol 295. 2017-08-14. PMID:28625590. |
posttraumatic stress disorder (ptsd), chronic psychological stress, and major depressive disorder have been found to be associated with a significant decrease in glial fibrillary acidic protein (gfap) immunoreactivity in the hippocampus of rodents. |
2017-08-14 |
2023-08-13 |
mouse |
| Gabriela Hurtado-Alvarado, Emilio Domínguez-Salazar, Javier Velázquez-Moctezuma, Beatriz Gómez-Gonzále. A2A Adenosine Receptor Antagonism Reverts the Blood-Brain Barrier Dysfunction Induced by Sleep Restriction. PloS one. vol 11. issue 11. 2017-08-01. PMID:27893847. |
in addition, we evaluated by western blot the expression of tight junction proteins (claudin-5, occludin, zo-1), adherens junction protein (e-cadherin), a2a adenosine receptor, adenosine-synthesizing enzyme (cd73), and neuroinflammatory markers (iba-1 and gfap) in the cerebral cortex, hippocampus, basal nuclei and cerebellar vermis. |
2017-08-01 |
2023-08-13 |
rat |
| Hai Song, Lincheng Xu, Rongping Zhang, Zhenzhen Cao, Huan Zhang, Li Yang, Zeyun Guo, Yongqiang Qu, Jianyun Y. Rosemary extract improves cognitive deficits in a rats model of repetitive mild traumatic brain injury associated with reduction of astrocytosis and neuronal degeneration in hippocampus. Neuroscience letters. vol 622. 2017-07-19. PMID:27113205. |
these behavioral alterations were accompanying with the increased neuronal degeneration and glial fibrillary acidic protein (gfap)-positive cells, increased reactive oxygen species (ros) generation, decreased activity of superoxide dismutase (sod), glutathione peroxidase (gpx) and catalase (cat), elevated protein level of il-1β, il-6 and tnf-α in hippocampus. |
2017-07-19 |
2023-08-13 |
rat |
| Daniela Pedroso, Ana R Nunes, Lucília N Diogo, Carole Oudot, Emília C Monteiro, Catherine Brenner, Helena L A Vieir. Hippocampal neurogenesis response: What can we expect from two different models of hypertension? Brain research. vol 1646. 2017-07-18. PMID:27235865. |
nevertheless, in hippocampus derived from cih-induced hypertensive rats, there was a decrease on neuronal population (map2 and neun positive cells) and an increase on astrocytic marker gfap. |
2017-07-18 |
2023-08-13 |
rat |
| He Huang, Cun-Ming Liu, Jie Sun, Ting Hao, Chun-Mei Xu, Dan Wang, Yu-Qing W. Ketamine Affects the Neurogenesis of the Hippocampal Dentate Gyrus in 7-Day-Old Rats. Neurotoxicity research. vol 30. issue 2. 2017-07-17. PMID:26966008. |
the expression of gfap in the hippocampal dg was measured by western blot analysis. |
2017-07-17 |
2023-08-13 |
rat |
| Juan Ji, Xiao-Ning Zeng, Lu-Lu Cao, Ling Zhang, Zhan Zhao, Dan-Dan Yang, Xiu-Lan Su. PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a. Neuropharmacology. vol 113. issue Pt A. 2017-07-11. PMID:27789312. |
corticosterone can significantly reduce the expression of glial fibrillary acid protein (gfap) in cultured rat hippocampal astrocytes in vitro, and induce astrocytic dysfunction. |
2017-07-11 |
2023-08-13 |
rat |
| Ya-Juan Zhu, Ke Peng, Xiao-Wen Meng, Fu-Hai J. Attenuation of neuroinflammation by dexmedetomidine is associated with activation of a cholinergic anti-inflammatory pathway in a rat tibial fracture model. Brain research. vol 1644. 2017-06-29. PMID:27163720. |
overexpression of microglial (cd11b) and astrocytic (gfap) responses to injury were observed in the hippocampus. |
2017-06-29 |
2023-08-13 |
rat |
| Camila P Almeida-Suhett, Alice Graham, Yifan Chen, Patricia Deuste. Behavioral changes in male mice fed a high-fat diet are associated with IL-1β expression in specific brain regions. Physiology & behavior. vol 169. 2017-06-28. PMID:27876639. |
additionally, hippocampal gfap and iba1 immunoreactivity were increased in hfd mice when compared to sd controls. |
2017-06-28 |
2023-08-13 |
mouse |
| Anne Günther, Vince Luczak, Ted Abel, Arnd Bauman. Caspase-3 and GFAP as early markers for apoptosis and astrogliosis in shRNA-induced hippocampal cytotoxicity. The Journal of experimental biology. vol 220. issue Pt 8. 2017-06-16. PMID:28167801. |
caspase-3 and gfap as early markers for apoptosis and astrogliosis in shrna-induced hippocampal cytotoxicity. |
2017-06-16 |
2023-08-13 |
mouse |
| Benjamin Seyer, Vi Pham, Anthony L Albiston, Siew Yeen Cha. Cannula implantation into the lateral ventricle does not adversely affect recognition or spatial working memory. Neuroscience letters. vol 628. 2017-06-13. PMID:27345383. |
both gfap and cd-11b mrna expression was elevated in the area immediately surrounding the cannulation site, but not in the contralateral hemisphere or the hippocampus. |
2017-06-13 |
2023-08-13 |
rat |
| Lina Clara Gayoso E Ibiapina Moreno, Elena Puerta, José Eduardo Suárez-Santiago, Nereide Stela Santos-Magalhães, Maria J Ramirez, Juan M Irach. Effect of the oral administration of nanoencapsulated quercetin on a mouse model of Alzheimer's disease. International journal of pharmaceutics. vol 517. issue 1-2. 2017-06-13. PMID:27915007. |
these observations appeared to be related with a decreased expression of the hippocampal astrocyte marker gfap. |
2017-06-13 |
2023-08-13 |
mouse |
| Daniel Juárez-Rebollar, Mario Alonso-Vanegas, Concepción Nava-Ruíz, Masao Buentello-García, Petra Yescas-Gómez, Araceli Díaz-Ruíz, Camilo Rios, Marisela Méndez-Arment. Immunohistochemical study of Metallothionein in patients with temporal lobe epilepsy. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 39. 2017-05-23. PMID:28087193. |
histopathological examination showed neun, gfap and mt immunopositive cells that were analyzed for determinate in hippocampal and parietal cortex samples. |
2017-05-23 |
2023-08-13 |
Not clear |
| Yang Liu, Yuanyuan Li, Tongwang Yang, Jing Yang, He Wang, Gang W. Acute changes in murine hippocampus and olfactory bulb after nasal instillation of varying size cerium dioxide particles. Journal of toxicology and environmental health. Part A. vol 79. issue 19. 2017-05-12. PMID:27599233. |
immunohistochemical data showed that glial fibrillary acidic protein expression (gfap) increased significantly in the hippocampus and olfactory bulb in all ce-administered groups. |
2017-05-12 |
2023-08-13 |
mouse |
| Mahboubeh Zarezadeh, Tourandokht Baluchnejadmojarad, Zahra Kiasalari, Siamak Afshin-Majd, Mehrdad Roghan. Garlic active constituent s-allyl cysteine protects against lipopolysaccharide-induced cognitive deficits in the rat: Possible involved mechanisms. European journal of pharmacology. vol 795. 2017-05-08. PMID:27915041. |
meanwhile, sac down-regulated hippocampal nuclear factor-b, toll-like receptor 4 (tlr4), glial fibrillary acidic protein (gfap), and interleukin 1β (il-1β) and up-regulated nuclear factor (erythroid-derived 2)-like 2 (nrf2) in addition to lowering iba1-immunoreactive intensity in the hippocampus of lps-injected group. |
2017-05-08 |
2023-08-13 |
rat |