| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hong Xu, Thomas W Rösler, Thomas Carlsson, Anderson de Andrade, Ondrej Fiala, Matthias Hollerhage, Wolfgang H Oertel, Michel Goedert, Achim Aigner, Gunter U Höglinge. Tau silencing by siRNA in the P301S mouse model of tauopathy. Current gene therapy. vol 14. issue 5. 2015-10-13. PMID:25687501. |
neun, gfap, iba-1, mhc ii immunoreactivities and the terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) assay showed neither signs of neurotoxicity or neuroinflammation nor apoptosis when mapt sirna is present in the hippocampus. |
2015-10-13 |
2023-08-13 |
mouse |
| Jessica L Seidel, Mathilde Faideau, Isamu Aiba, Ulrike Pannasch, Carole Escartin, Nathalie Rouach, Gilles Bonvento, C William Shuttlewort. Ciliary neurotrophic factor (CNTF) activation of astrocytes decreases spreading depolarization susceptibility and increases potassium clearance. Glia. vol 63. issue 1. 2015-09-14. PMID:25092804. |
injection of a lentiviral vector encoding ciliary neurotrophic factor (cntf) into the hippocampus in vivo, led to sustained astrocyte activation, verified by up-regulation of glial fibrillary acidic protein (gfap) at the mrna and protein levels, as compared to controls injected with vector encoding lacz. |
2015-09-14 |
2023-08-13 |
Not clear |
| Fernando Jauregui-Huerta, Limei Zhang, Griselda Yañez-Delgadillo, Pamela Hernandez-Carrillo, Joaquín García-Estrada, Sonia Luquí. Hippocampal cytogenesis and spatial learning in senile rats exposed to chronic variable stress: effects of previous early life exposure to mild stress. Frontiers in aging neuroscience. vol 7. 2015-09-08. PMID:26347648. |
immunohistochemistry against 5'bromodeoxyuridine (brdu) and glial fibrillar acidic protein (gfap) was also conducted in the dg, ca1, ca2 and ca3 regions of the hippocampus. |
2015-09-08 |
2023-08-13 |
human |
| Fernando Jauregui-Huerta, Limei Zhang, Griselda Yañez-Delgadillo, Pamela Hernandez-Carrillo, Joaquín García-Estrada, Sonia Luquí. Hippocampal cytogenesis and spatial learning in senile rats exposed to chronic variable stress: effects of previous early life exposure to mild stress. Frontiers in aging neuroscience. vol 7. 2015-09-08. PMID:26347648. |
using this procedure, we found that stress diminished the total number of brdu+ cells over the main proliferative area of the hippocampus (i.e., the dentate gyrus, dg) but increased the astrocyte phenotypes (gfap + brdu). |
2015-09-08 |
2023-08-13 |
human |
| José Christian Machado Ximenes, Kelly Rose Tavares Neves, Luzia Kalyne A M Leal, Marta Regina Santos do Carmo, Gerly Anne de Castro Brito, Maria da Graça Naffah-Mazzacoratti, Ésper Abrão Cavalheiro, Glauce Socorro de Barros Vian. Valproic Acid Neuroprotection in the 6-OHDA Model of Parkinson's Disease Is Possibly Related to Its Anti-Inflammatory and HDAC Inhibitory Properties. Journal of neurodegenerative diseases. vol 2015. 2015-08-28. PMID:26317011. |
then, they were sacrificed and had their mesencephalon, striatum, and hippocampus dissected for neurochemical (da and dopac determinations), histological (fluoro-jade staining), and immunohistochemistry evaluations (th, ox-42, gfap, tnf-alpha, and hdac). |
2015-08-28 |
2023-08-13 |
rat |
| Min Ning, Yiying Wu, Xiushi Ni, Yanling Zhao, Rujing Lin. Cerebral microemboli increase β-amyloid protein deposition, MMP-9, and GFAP expression in the Alzheimer`s model of APP/PS1 double transgenic mice. Current neurovascular research. vol 11. issue 3. 2015-08-21. PMID:24962158. |
after the mouse model was established for 1, 2 or 4 weeks, the aβ1-42 deposition in the left hippocampal region and the matrix metalloproteinase-9 (mmp-9) and glial fibrillary acidic protein (gfap) expression levels were determined through immunohistochemical staining. |
2015-08-21 |
2023-08-13 |
mouse |
| Yu-Wen Hung, Shao-Wen Hung, Yi-Chen Wu, Lin-King Wong, Ming-Tsong Lai, Yang-Hsin Shih, Tzong-Shyuan Lee, Yung-Yang Li. Soluble epoxide hydrolase activity regulates inflammatory responses and seizure generation in two mouse models of temporal lobe epilepsy. Brain, behavior, and immunity. vol 43. 2015-08-07. PMID:25135858. |
in the hippocampus of wt mice, seh was mainly expressed in astrocytes (gfap(+)), neurons (neun(+)) and scattered microglia (iba-1(+)) in the regions of ca1, ca3 and dentate gyrus. |
2015-08-07 |
2023-08-13 |
mouse |
| Shaimaa Nasr Amin, Sarah Mahmoud Gamal, Reham Shehab El Nemr Esmail, Tarek Mohamed Abdel Aziz, Laila Ahmed Rashe. Cognitive effects of acute restraint stress in male albino rats and the impact of pretreatment with quetiapine versus ghrelin. Journal of integrative neuroscience. vol 13. issue 4. 2015-07-22. PMID:25391717. |
this study aimed to investigate the effect of acute restraint stress (ars) on cognitive performance by measuring spatial working memory in y-maze, behavior (anxiety and exploratory behavior) in open field test, expression of synaptophysin and glial fibrillary acidic protein (gfap) in the hippocampus by immunohistochemistry, dopaminergic receptors (d2) in the basal ganglia by gene expression and comparing the effect of ghrelin and quetiapine on the previous parameters. |
2015-07-22 |
2023-08-13 |
rat |
| Dongling Zhang, Qian Xiao, Huiqiong Luo, Kexiang Zha. [Effects of angiotensin-(1-7) on hippocampal expressions of GFAP and GDNF and cognitive function in rats with diabetes mellitus]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 35. issue 5. 2015-07-20. PMID:26018256. |
[effects of angiotensin-(1-7) on hippocampal expressions of gfap and gdnf and cognitive function in rats with diabetes mellitus]. |
2015-07-20 |
2023-08-13 |
rat |
| Dongling Zhang, Qian Xiao, Huiqiong Luo, Kexiang Zha. [Effects of angiotensin-(1-7) on hippocampal expressions of GFAP and GDNF and cognitive function in rats with diabetes mellitus]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 35. issue 5. 2015-07-20. PMID:26018256. |
to explore the effects of angiotensin-(1-7) on the learning and memory abilities and the expressions of glial fibrillary acidic protein (gfap) and glial cell line-derived neurotrophic factor (gdnf) in the hippocampus of diabetic rats. |
2015-07-20 |
2023-08-13 |
rat |
| P Sampedro-Piquero, Paola De Bartolo, Laura Petrosini, C Zancada-Menendez, J L Arias, A Begeg. Astrocytic plasticity as a possible mediator of the cognitive improvements after environmental enrichment in aged rats. Neurobiology of learning and memory. vol 114. 2015-05-22. PMID:24727294. |
given the newly discovered role of the astrocytes in regulating the synaptic transmission and thereby, the cognitive functions, we aimed to study the impact of ee on the performance in a spatial memory task and on the number and morphology of gfap immunopositive cells in the dorsal hippocampus. |
2015-05-22 |
2023-08-13 |
rat |
| P Sampedro-Piquero, Paola De Bartolo, Laura Petrosini, C Zancada-Menendez, J L Arias, A Begeg. Astrocytic plasticity as a possible mediator of the cognitive improvements after environmental enrichment in aged rats. Neurobiology of learning and memory. vol 114. 2015-05-22. PMID:24727294. |
also, we found that aged rats submitted to ee had more gfap immunopositive cells in the dg and more complex astrocytes, revealed by sholl analysis, in all hippocampal subfields with respect to the other experimental conditions. |
2015-05-22 |
2023-08-13 |
rat |
| C L Jiang, M Huang, X F An, W Q Zhan. [Expression of regulation protein of glial fibrillary acidic protein gene in hippocampus of epileptic rats induced by kainic acid]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 17. issue 4. 2015-05-16. PMID:21207701. |
the dna binding protein from hippocampus of epileptic rats was investigated by southwestern blot, which regulated the expression of glial fibrillary acidic protein (gfap) gene. |
2015-05-16 |
2023-08-12 |
rat |
| Berta Anuncibay-Soto, Diego Pérez-Rodríguez, Irene L Llorente, Marta Regueiro-Purriños, José Manuel Gonzalo-Orden, Arsenio Fernández-Lópe. Age-dependent modifications in vascular adhesion molecules and apoptosis after 48-h reperfusion in a rat global cerebral ischemia model. Age (Dordrecht, Netherlands). vol 36. issue 5. 2015-05-12. PMID:25182537. |
the adhesion molecules e- and p-selectin, cell adhesion molecules (cams), both intercellular (icam-1) and vascular (vcam-1), as well as glial fibrillary acidic protein (gfap), and cleaved caspase-3 were measured at 48 h after ischemia in the cerebral cortex and hippocampus using western blot, qpcr and immunofluorescence techniques. |
2015-05-12 |
2023-08-13 |
rat |
| Ya A Zorkina, G M Yusubalieva, F A Koshkin, A Yu Chamorsov, A V Kistenev, G E Gorlachev, A V Golanov, A A Potapov, V P Chekhoni. Expression of VEGF, GFAP, and BDNF genes in the brain of rats after fractionated γ-irradiation according to different protocols. Bulletin of experimental biology and medicine. vol 157. issue 4. 2015-04-20. PMID:25110093. |
in the hippocampus, the expression of gfap was low only after week 12. |
2015-04-20 |
2023-08-13 |
rat |
| Patricia Rivera, Laura Bindila, Antoni Pastor, Margarita Pérez-Martín, Francisco J Pavón, Antonia Serrano, Rafael de la Torre, Beat Lutz, Fernando Rodríguez de Fonseca, Juan Suáre. Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothalamus and striatum in a negative energy context. Frontiers in cellular neuroscience. vol 9. 2015-04-14. PMID:25870539. |
cell proliferation (phospho-h3(+) or brdu(+) cells) of the main adult neurogenic zones as well as apoptosis (cleaved caspase-3(+)), astroglia (gfap(+)), and microglia (iba1(+) cells) were analyzed in the hippocampus, hypothalamus and striatum of rats intraperitoneally treated with urb597 (0.3 mg/kg/day) at one dose/4-days resting or 5 doses (1 dose/day). |
2015-04-14 |
2023-08-13 |
rat |
| Patricia Rivera, Laura Bindila, Antoni Pastor, Margarita Pérez-Martín, Francisco J Pavón, Antonia Serrano, Rafael de la Torre, Beat Lutz, Fernando Rodríguez de Fonseca, Juan Suáre. Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothalamus and striatum in a negative energy context. Frontiers in cellular neuroscience. vol 9. 2015-04-14. PMID:25870539. |
the hippocampi of repeated urb597-treated rats showed a reduced number of phospho-h3(+) and brdu(+) subgranular cells as well as gfap(+), iba1(+) and cleaved caspase-3(+) cells, which was accompanied with decreased hippocampal expression of the cannabinoid cb1 receptor gene cnr1 and faah. |
2015-04-14 |
2023-08-13 |
rat |
| Hai-Yan Hu, Lei Lei, Xiang Chen, Wen-Hua Wang, Xiao-Yan Zhan. [Effects of qingxin kaiqiao recipe volatile oil on expressions of GFAP and caspase-3 in the cortex and hippocampus of AD rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 33. issue 7. 2015-04-11. PMID:24063215. |
[effects of qingxin kaiqiao recipe volatile oil on expressions of gfap and caspase-3 in the cortex and hippocampus of ad rats]. |
2015-04-11 |
2023-08-12 |
rat |
| Hai-Yan Hu, Lei Lei, Xiang Chen, Wen-Hua Wang, Xiao-Yan Zhan. [Effects of qingxin kaiqiao recipe volatile oil on expressions of GFAP and caspase-3 in the cortex and hippocampus of AD rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 33. issue 7. 2015-04-11. PMID:24063215. |
to study effects of qingxin kaiqiao recipe (qkr) and its volatile oil on the expressions of abeta(25-35) glial fibrillary acidic protein (gfap), beta-amyloid (abeta), beta-amyloid precursor protein (betaapp), and caspase-3 in the cortex and hippocampus of alzheimer's disease (ad) rats induced by injecting abeta(25-35) into the bilateral amygdala. |
2015-04-11 |
2023-08-12 |
rat |
| Alicia Raquel Rossi, Maria Florencia Angelo, Alejandro Villarreal, Jerónimo Lukin, Alberto Javier Ramo. Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus. PloS one. vol 8. issue 11. 2015-03-30. PMID:24250797. |
during the latency period, the hippocampus and pyriform cortex of se-animals presented a profuse reactive astrogliosis, with increased gfap and nestin expression. |
2015-03-30 |
2023-08-12 |
human |