| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sinead O'Donovan, Victoria Dalton, Andrew Harkin, Declan M McLoughli. Effects of brief pulse and ultrabrief pulse electroconvulsive stimulation on rodent brain and behaviour in the corticosterone model of depression. The international journal of neuropsychopharmacology. vol 17. issue 9. 2015-03-30. PMID:24607259. |
corticosterone administration resulted in an increase in immobility time in the forced swim test (fst) (p < 0.01) and decreases in the expression of brain-derived neurotrophic factor (bdnf) (p < 0.05) and glial fibrillary acidic protein (gfap) (p < 0.001) in the hippocampus and frontal cortex. |
2015-03-30 |
2023-08-12 |
rat |
| Sinead O'Donovan, Victoria Dalton, Andrew Harkin, Declan M McLoughli. Effects of brief pulse and ultrabrief pulse electroconvulsive stimulation on rodent brain and behaviour in the corticosterone model of depression. The international journal of neuropsychopharmacology. vol 17. issue 9. 2015-03-30. PMID:24607259. |
bp ecs (p < 0.05) but not ubp ecs induced a significant increase in gfap levels in the hippocampus and frontal cortex. |
2015-03-30 |
2023-08-12 |
rat |
| Juntian Liu, Baixiao Zhao, Yingxue Cui, Yuhai Huang, Chang Huang, Jian Huang, Li Han, Lixing La. Effects of shenque moxibustion on behavioral changes and brain oxidative state in apolipoprotein e-deficient mice. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-03-20. PMID:25793004. |
in immune-histochemical study, the moxibustion group expressed lower level of gfap and less aggregation of β-amyloid in the hippocampus than the sham control. |
2015-03-20 |
2023-08-13 |
mouse |
| Giuseppina Cantarella, Giulia Di Benedetto, Daniela Puzzo, Lucia Privitera, Carla Loreto, Salvatore Saccone, Salvatore Giunta, Agostino Palmeri, Renato Bernardin. Neutralization of TNFSF10 ameliorates functional outcome in a murine model of Alzheimer's disease. Brain : a journal of neurology. vol 138. issue Pt 1. 2015-03-02. PMID:25472798. |
the effects of tnfsf10 neutralization on either cognitive parameters, as well as on the expression of tnfsf10, amyloid-β, inflammatory mediators and gfap were studied in the hippocampus of 3xtg-ad mice. |
2015-03-02 |
2023-08-13 |
mouse |
| Giuseppina Cantarella, Giulia Di Benedetto, Daniela Puzzo, Lucia Privitera, Carla Loreto, Salvatore Saccone, Salvatore Giunta, Agostino Palmeri, Renato Bernardin. Neutralization of TNFSF10 ameliorates functional outcome in a murine model of Alzheimer's disease. Brain : a journal of neurology. vol 138. issue Pt 1. 2015-03-02. PMID:25472798. |
these results were correlated with decreased protein expression of tnfsf10, amyloid-β, inflammatory mediators and gfap in the hippocampus. |
2015-03-02 |
2023-08-13 |
mouse |
| Giordano Gubert Viola, Cássio Morais Los. Letter to Editor about: "Physical exercise increases GFAP expression and induces morphological changes in hippocampal astrocytes". Brain structure & function. vol 219. issue 4. 2015-02-23. PMID:23644588. |
letter to editor about: "physical exercise increases gfap expression and induces morphological changes in hippocampal astrocytes". |
2015-02-23 |
2023-08-12 |
Not clear |
| Daniela Boassa, Phuong Nguyen, Junru Hu, Mark H Ellisman, Gina E Sosinsk. Pannexin2 oligomers localize in the membranes of endosomal vesicles in mammalian cells while Pannexin1 channels traffic to the plasma membrane. Frontiers in cellular neuroscience. vol 8. 2015-02-20. PMID:25698922. |
confocal images of hippocampal sections immunolabeled for the astrocytic protein gfap, panx1 and panx2 demonstrated that the two isoforms, panx1 and panx2, localized at different subcellular compartments in both astrocytes and neurons. |
2015-02-20 |
2023-08-13 |
Not clear |
| Robert J Schloesser, Dennisse V Jimenez, Nicholas F Hardy, Daniel Paredes, Briony J Catlow, Husseini K Manji, Ronald D McKay, Keri Martinowic. Atrophy of pyramidal neurons and increased stress-induced glutamate levels in CA3 following chronic suppression of adult neurogenesis. Brain structure & function. vol 219. issue 3. 2015-02-04. PMID:23483239. |
we investigated whether loss of new neurons impacts dendrite morphology and glutamate levels in area ca3 of the hippocampus by utilizing a human gfap promoter-driven thymidine kinase genetic mouse model to conditionally suppress adult neurogenesis. |
2015-02-04 |
2023-08-12 |
mouse |
| b' Du\\xc5\\xa1an Mladenovi\\xc4\\x87, Dragan Hrn\\xc4\\x8di\\xc4\\x87, Nata\\xc5\\xa1a Petronijevi\\xc4\\x87, Gordana Jevti\\xc4\\x87, Tatjana Radosavljevi\\xc4\\x87, Aleksandra Ra\\xc5\\xa1i\\xc4\\x87-Markovi\\xc4\\x87, Nela Pu\\xc5\\xa1ka\\xc5\\xa1, Neboj\\xc5\\xa1a Maksi\\xc4\\x87, Olivera Stanojlovi\\xc4\\x8. Finasteride improves motor, EEG, and cellular changes in rat brain in thioacetamide-induced hepatic encephalopathy. American journal of physiology. Gastrointestinal and liver physiology. vol 307. issue 9. 2015-01-16. PMID:25104500.' |
cortical iba1 expression was significantly higher in experimental groups vs. control (p < 0.05), whereas hippocampal gfap expression was increased in taa and decreased in the fin + taa group vs. control (p < 0.05). |
2015-01-16 |
2023-08-13 |
rat |
| Diana I Rodrigues, Jessié Gutierres, Anna Pliássova, Catarina R Oliveira, Rodrigo A Cunha, Paula Agostinh. Synaptic and sub-synaptic localization of amyloid-β protein precursor in the rat hippocampus. Journal of Alzheimer's disease : JAD. vol 40. issue 4. 2015-01-06. PMID:24531160. |
we also observed a general lack of co-localization of aβpp and gfap immunoreactivities in the hippocampus of sections of adult rat brain, albeit we could detect the presence of aβpp in gliosomes (vesicular specializations of astrocytic membranes), suggesting that aβpp has a heterogeneous localization restricted to certain regions of astrocytes. |
2015-01-06 |
2023-08-12 |
rat |
| Marcus Boehme, Madlen Guenther, Anna Stahr, Marie Liebmann, Nadine Jaenisch, Otto W Witte, Christiane Frah. Impact of indomethacin on neuroinflammation and hippocampal neurogenesis in aged mice. Neuroscience letters. vol 572. 2014-12-23. PMID:24796813. |
during hippocampal aging, the transcript expression of pro-inflammatory cytokines (tnfα, il-1α, il-1β), the chemokine mip-1α, and markers for activated astrocytes (gfap, lcn2, but not vim and serpina3n) and microglia (iba1, f4/80, cd68, cd86) significantly increased. |
2014-12-23 |
2023-08-13 |
mouse |
| Marcus Boehme, Madlen Guenther, Anna Stahr, Marie Liebmann, Nadine Jaenisch, Otto W Witte, Christiane Frah. Impact of indomethacin on neuroinflammation and hippocampal neurogenesis in aged mice. Neuroscience letters. vol 572. 2014-12-23. PMID:24796813. |
of the age-related inflammatory mediators, only gfap and iba1 were affected by indomethacin treatment in the hippocampus, with a significantly reduced transcript expression being detected for both markers. |
2014-12-23 |
2023-08-13 |
mouse |
| L Pietranera, M E Brocca, P Roig, A Lima, L M Garcia-Segura, A F De Nicol. 17α-Oestradiol-induced neuroprotection in the brain of spontaneously hypertensive rats. Journal of neuroendocrinology. vol 26. issue 5. 2014-12-08. PMID:24730417. |
in the brain, we analysed steroid effects on hippocampus ki67+ proliferating cells, doublecortin (dcx) positive neuroblasts, glial fibrillary acidic protein (gfap)+ astrocyte density, aromatase immunostaining and brain-derived neurotrophic factor (bdnf) mrna. |
2014-12-08 |
2023-08-13 |
rat |
| Hamid Kalalian Moghaddam, Tourandokht Baluchnejadmojarad, Mehrdad Roghani, Mehdi Khaksari, Pirasteh Norouzi, Malihea Ahooie, Fatemeh Mahboob. Berberine ameliorate oxidative stress and astrogliosis in the hippocampus of STZ-induced diabetic rats. Molecular neurobiology. vol 49. issue 2. 2014-11-21. PMID:24113841. |
therefore, we examined the effects of berberine on glial reactivity of hippocampus in streptozotocin (stz)-induced diabetic rats, using gfap immunohistochemistry. |
2014-11-21 |
2023-08-12 |
rat |
| Hamid Kalalian Moghaddam, Tourandokht Baluchnejadmojarad, Mehrdad Roghani, Mehdi Khaksari, Pirasteh Norouzi, Malihea Ahooie, Fatemeh Mahboob. Berberine ameliorate oxidative stress and astrogliosis in the hippocampus of STZ-induced diabetic rats. Molecular neurobiology. vol 49. issue 2. 2014-11-21. PMID:24113841. |
eight weeks after diabetes induction, we observed increased numbers of gfap(+) astrocytes immunostaining associated with increased lipid peroxidation, decreased superoxide dismutase activity, and elevated nitrite levels in the hippocampus of stz-diabetic rats. |
2014-11-21 |
2023-08-12 |
rat |
| Ji-Zhong Bai, Janusz Lipsk. Involvement of TRPV4 channels in Aβ(40)-induced hippocampal cell death and astrocytic Ca(2+) signalling. Neurotoxicology. vol 41. 2014-11-14. PMID:24457011. |
in disassociated co-cultures of hippocampal neurons and astrocytes without bso preconditioning, aβ40 evoked pronounced neuronal damage, enhanced the expression of trpv4 and gfap proteins (indicative of reactive astrogliosis), and increased intracellular free ca(2+) concentration in astrocytes. |
2014-11-14 |
2023-08-12 |
rat |
| C R Yang, Z G Zhang, Y Y Bai, H Fiona Zhou, L Zhou, C S Ruan, F Li, C Q Li, H Y Zheng, L J Shen, X F Zho. Foraging activity is reduced in a mouse model of depression. Neurotoxicity research. vol 25. issue 3. 2014-11-05. PMID:23873577. |
in addition, the treatment of anti-depressant fluoxetine reversed most depressive symptoms and reduced glial fibrillary associated protein (gfap) expression in the hippocampus, but was less effective in the reduction of foraging activities. |
2014-11-05 |
2023-08-12 |
mouse |
| C R Yang, Z G Zhang, Y Y Bai, H Fiona Zhou, L Zhou, C S Ruan, F Li, C Q Li, H Y Zheng, L J Shen, X F Zho. Foraging activity is reduced in a mouse model of depression. Neurotoxicity research. vol 25. issue 3. 2014-11-05. PMID:23873577. |
however, clozapine reversed all symptoms of cums-exposed mice including reduction of gfap expression in the hippocampus and impaired foraging activity. |
2014-11-05 |
2023-08-12 |
mouse |
| Feng Liu, Fan Liao, Wei Li, Yongfeng Han, Daguang Lia. Progesterone alters Nogo-A, GFAP and GAP-43 expression in a rat model of traumatic brain injury. Molecular medicine reports. vol 9. issue 4. 2014-10-21. PMID:24567055. |
the protein expression of nogo-a, gfap and gap-43 in the cortex and the hippocampus was examined by immunocytochemistry. |
2014-10-21 |
2023-08-12 |
rat |
| Willem Kamphuis, Jinte Middeldorp, Lieneke Kooijman, Jacqueline A Sluijs, Evert-Jan Kooi, Martina Moeton, Michel Freriks, Mark R Mizee, Elly M Ho. Glial fibrillary acidic protein isoform expression in plaque related astrogliosis in Alzheimer's disease. Neurobiology of aging. vol 35. issue 3. 2014-09-29. PMID:24269023. |
we studied transcript levels and protein expression patterns of all known gfap isoforms in human hippocampal ad tissue at different stages of the disease. |
2014-09-29 |
2023-08-12 |
human |