All Relations between fatty acid amide hydrolase and cannabinoids

Publication Sentence Publish Date Extraction Date Species
M Egertov√°, D K Giang, B F Cravatt, M R Elphic. A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain. Proceedings. Biological sciences. vol 265. issue 1410. 1998-12-22. PMID:9842734. the close correspondence in the distribution of faah and cb1 in rat brain and the complementary pattern of faah and cb1 expression at the cellular level provides important new evidence that faah may participate in cannabinoid signalling mechanisms of the brain. 1998-12-22 2023-08-12 rat
J Barnett-Norris, F Guarnieri, D P Hurst, P H Reggi. Exploration of biologically relevant conformations of anandamide, 2-arachidonylglycerol, and their analogues using conformational memories. Journal of medicinal chemistry. vol 41. issue 24. 1998-12-17. PMID:9822555. such rigid analogues may be useful in deducing the bioactive conformation of these endogenous cannabinoids, not only at the cb receptors but also at the faah enzyme active site and possibly at the binding site(s) on the newly proposed anandamide transporter. 1998-12-17 2023-08-12 Not clear
T Bisogno, N Sepe, L De Petrocellis, R Mechoulam, V Di Marz. The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. Biochemical and biophysical research communications. vol 239. issue 2. 1997-11-17. PMID:9344854. the enzyme catalyzing the hydrolysis of the amide bond of oleamide as well as of anandamide, the putative endogenous ligand of cannabinoid receptors, was purified from rat liver, cloned, shown to be expressed also in brain and named fatty acid amide hydrolase (faah). 1997-11-17 2023-08-12 mouse