| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Wang, Zihao Xia, Peng Sheng, Yanggang Rui, Jianwen Cao, Jie Zhang, Manman Gao, Li Wang, Duonan Yu, Bing Chun Ya. Targeting MicroRNA-144/451-AKT-GSK3β Axis Affects the Proliferation and Differentiation of Radial Glial Cells in the Mouse Hippocampal Dentate Gyrus. ACS chemical neuroscience. 2022-03-09. PMID:35261236. |
it is well known that aging induces a progressive decline in the proliferation and neural differentiation of radial glial cells (rgcs) in the hippocampal dentate gyrus (dg). |
2022-03-09 |
2023-08-13 |
mouse |
| Jie Wang, Zihao Xia, Peng Sheng, Yanggang Rui, Jianwen Cao, Jie Zhang, Manman Gao, Li Wang, Duonan Yu, Bing Chun Ya. Targeting MicroRNA-144/451-AKT-GSK3β Axis Affects the Proliferation and Differentiation of Radial Glial Cells in the Mouse Hippocampal Dentate Gyrus. ACS chemical neuroscience. 2022-03-09. PMID:35261236. |
furthermore, the proliferation and neural differentiation of rgcs in the mouse hippocampal dg was decreased by mir-144/451 knockout (mir-144/451 |
2022-03-09 |
2023-08-13 |
mouse |
| Hongxuan Kuang, Wenji Zhou, Yingwei Zeng, Da Xu, Wanqi Zhu, Shengjie Lin, Ruifang Fa. Dose makes poison: Insights into the neurotoxicity of perinatal and juvenile exposure to environmental doses of 16 priority-controlled PAHs. Chemosphere. 2022-03-08. PMID:35257710. |
compared with the control mice, only those exposed to 50 μg/kg/day pahs had significantly lower ltp in hippocampal ca1 region and dendritic spine density in hippocampal dg region (p < 0.05). |
2022-03-08 |
2023-08-13 |
mouse |
| Dasiel O Borroto-Escuela, Ramón Fores, Mariana Pita, Miguel A Barbancho, Pablo Zamorano-Gonzalez, Natalia García Casares, Kjell Fuxe, Manuel Narváe. Intranasal Delivery of Galanin 2 and Neuropeptide Y1 Agonists Enhanced Spatial Memory Performance and Neuronal Precursor Cells Proliferation in the Dorsal Hippocampus in Rats. Frontiers in pharmacology. vol 13. 2022-03-07. PMID:35250569. |
moreover, we observed the ability of the co-agonist treatment to enhance the cell proliferation in the dg of the dorsal hippocampus through 5- bromo-2'-deoxyuridine (brdu) expression analysis at 24 hours. |
2022-03-07 |
2023-08-13 |
rat |
| Bin Qiu, Zhaohui Zhong, Shawn Righter, Yuxue Xu, Jun Wang, Ran Deng, Chao Wang, Kent E Williams, Yao-Ying Ma, Gavriil Tsechpenakis, Tiebing Liang, Weidong Yon. FKBP51 modulates hippocampal size and function in post-translational regulation of Parkin. Cellular and molecular life sciences : CMLS. vol 79. issue 3. 2022-03-04. PMID:35244772. |
artificial intelligence-assisted morphological analysis revealed that male fkbp51 knock-out (ko) mice possess more elongated dentate gyrus (dg) but shorter hippocampal height in coronal sections when compared to wt. |
2022-03-04 |
2023-08-13 |
mouse |
| Bin Qiu, Zhaohui Zhong, Shawn Righter, Yuxue Xu, Jun Wang, Ran Deng, Chao Wang, Kent E Williams, Yao-Ying Ma, Gavriil Tsechpenakis, Tiebing Liang, Weidong Yon. FKBP51 modulates hippocampal size and function in post-translational regulation of Parkin. Cellular and molecular life sciences : CMLS. vol 79. issue 3. 2022-03-04. PMID:35244772. |
ko has more flattened hippocampus using ai-assisted measurement both pyramidal cell layer (pcl) of ca and granular cell layer (gcl) of dg distinguishable as two layers: deep cell layer and superficial layer. distinct map2 expression between deep and superficial layer between ko and wt, higher parkin expression in ko brain mechanism of fkbp51 inhibition resulting in parkin, map2, tau, and tubulin expression differences between ko and wt mice, and resulting neurite outgrowth differences. |
2022-03-04 |
2023-08-13 |
mouse |
| Yasunori Takahashi, Hiromu Okano, Kazumi Takashima, Ryota Ojiro, Qian Tang, Shunsuke Ozawa, Bunichiro Ogawa, Gye-Hyeong Woo, Toshinori Yoshida, Makoto Shibutan. Oral exposure to high-dose ethanol for 28 days in rats reduces neural stem cells and immediate nascent neural progenitor cells as well as FOS-expressing newborn granule cells in adult hippocampal neurogenesis. Toxicology letters. 2022-03-01. PMID:35227807. |
in rats, developmental exposure to ethanol (etoh) at high doses has shown to induce aberrant neurogenesis in neural progenitor cells (npcs) during weaning and suppress synaptic plasticity of newborn granule cells after maturation; neuroinflammation was even sustained until the adult stage in the hippocampal dentate gyrus (dg). |
2022-03-01 |
2023-08-13 |
rat |
| Sung-Kuk Cho, Suhyun Gwon, Hyun Ah Kim, Jiwon Kim, Sung Yoo Cho, Dong-Eog Kim, Jong-Hee Chae, Dae Hwi Park, Yu Kyeong Hwan. Abnormal Development of Neural Stem Cell Niche in the Dentate Gyrus of Menkes Disease. International journal of stem cells. 2022-02-27. PMID:35220279. |
neural stem cells (nscs) in the hippocampal dentate gyrus (dg) produce new neurons throughout life, and defects in dg neurogenesis are often correlated with cognitive and behavioral problems. |
2022-02-27 |
2023-08-13 |
Not clear |
| Sang-Yoon Kim, Woochang Li. Dynamical origin for winner-take-all competition in a biological network of the hippocampal dentate gyrus. Physical review. E. vol 105. issue 1-1. 2022-02-23. PMID:35193268. |
we consider a biological network of the hippocampal dentate gyrus (dg). |
2022-02-23 |
2023-08-13 |
Not clear |
| Sang-Yoon Kim, Woochang Li. Dynamical origin for winner-take-all competition in a biological network of the hippocampal dentate gyrus. Physical review. E. vol 105. issue 1-1. 2022-02-23. PMID:35193268. |
computational models suggest that the dg would be a preprocessor for pattern separation (i.e., a process transforming a set of similar input patterns into distinct nonoverlapping output patterns) which could facilitate pattern storage and retrieval in the ca3 area of the hippocampus. |
2022-02-23 |
2023-08-13 |
Not clear |
| Jing Wu, Tingjia Chai, Hanping Zhang, Yu Huang, Seth W Perry, Yifan Li, Jiajia Duan, Xunmin Tan, Xi Hu, Yiyun Liu, Juncai Pu, Haiyang Wang, Jinlin Song, Xin Jin, Ping Ji, Peng Zheng, Peng Xi. Changes in gut viral and bacterial species correlate with altered 1,2-diacylglyceride levels and structure in the prefrontal cortex in a depression-like non-human primate model. Translational psychiatry. vol 12. issue 1. 2022-02-23. PMID:35194021. |
in addition, lipid-reaction analysis identified more active and inactive lipid pathways in pfc than in amygdala or hippocampus, with dg being a key nodal player in these lipid pathways. |
2022-02-23 |
2023-08-13 |
monkey |
| Hannah Twarkowksi, Victor Steininger, Min Jae Kim, Amar Saha. A dentate gyrus- CA3 inhibitory circuit promotes evolution of hippocampal-cortical ensembles during memory consolidation. eLife. vol 11. 2022-02-22. PMID:35191834. |
memories encoded in the dentate gyrus (dg) - ca3 circuit of the hippocampus are routed from ca1 to anterior cingulate cortex (acc) for consolidation. |
2022-02-22 |
2023-08-13 |
Not clear |
| Ying Hao Yu, Yeou San Lim, Chen Yin Ou, Kai Chieh Chang, Arthur C Tsai, Fang Chih Chang, Andrew Chih Wei Huan. The Medial Prefrontal Cortex, Nucleus Accumbens, Basolateral Amygdala, and Hippocampus Regulate the Amelioration of Environmental Enrichment and Cue in Fear Behavior in the Animal Model of PTSD. Behavioural neurology. vol 2022. 2022-02-18. PMID:35178125. |
the present study addressed this issue and examined whether the medial prefrontal cortex (mpfc, including the cingulate cortex 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), the nucleus accumbens (nac), the basolateral amygdala (bla), and the hippocampus (e.g., ca1, ca3, and dentate gyrus (dg)) regulated the amelioration of the ee, cue, or the combination of ee and cue. |
2022-02-18 |
2023-08-13 |
Not clear |
| Ying Hao Yu, Yeou San Lim, Chen Yin Ou, Kai Chieh Chang, Arthur C Tsai, Fang Chih Chang, Andrew Chih Wei Huan. The Medial Prefrontal Cortex, Nucleus Accumbens, Basolateral Amygdala, and Hippocampus Regulate the Amelioration of Environmental Enrichment and Cue in Fear Behavior in the Animal Model of PTSD. Behavioural neurology. vol 2022. 2022-02-18. PMID:35178125. |
the mpfc (i.e., the cg1, prl, and il) and the hippocampus (i.e., the ca1, ca3, and dg) downregulated the c-fos expression in the suppression of the cue in fear behavior. |
2022-02-18 |
2023-08-13 |
Not clear |
| Izabela Figiel, Ewa Bączyńska, Tomasz Wójtowicz, Marta Magnowska, Anna Buszka, Monika Bijata, Jakub Włodarczy. The cell adhesion protein dystroglycan affects the structural remodeling of dendritic spines. Scientific reports. vol 12. issue 1. 2022-02-16. PMID:35169214. |
here, we report for the first time that the deletion of dg in rat hippocampal cell cultures causes pronounced changes in the density and morphology of dendritic spines. |
2022-02-16 |
2023-08-13 |
rat |
| Claudius E Degro, Felix Bolduan, Imre Vida, Sam A Booke. Interneuron diversity in the rat dentate gyrus: An unbiased in vitro classification. Hippocampus. 2022-02-16. PMID:35171512. |
in the major input region of the hippocampus, the dentate gyrus (dg), a number of in types have been described which provide synaptic inhibition to distinct compartments of excitatory principal cells (prcs) and other ins. |
2022-02-16 |
2023-08-13 |
rat |
| Ana R Machado-Santos, Eduardo Loureiro-Campos, Patrícia Patrício, Bruna Araújo, Nuno Dinis Alves, António Mateus-Pinheiro, Joana Sofia Correia, Mónica Morais, João M Bessa, Nuno Sousa, Ana J Rodrigues, João Filipe Oliveira, Luísa Pint. Beyond New Neurons in the Adult Hippocampus: Imipramine Acts as a Pro-Astrogliogenic Factor and Rescues Cognitive Impairments Induced by Stress Exposure. Cells. vol 11. issue 3. 2022-02-15. PMID:35159199. |
therefore, we studied the modulation of astrocytes and adult astrogliogenesis in the hippocampal dentate gyrus (dg) of rats exposed to an unpredictable chronic mild stress (ucms) protocol, untreated and treated for two weeks with antidepressants-fluoxetine and imipramine. |
2022-02-15 |
2023-08-13 |
rat |
| Ana R Machado-Santos, Eduardo Loureiro-Campos, Patrícia Patrício, Bruna Araújo, Nuno Dinis Alves, António Mateus-Pinheiro, Joana Sofia Correia, Mónica Morais, João M Bessa, Nuno Sousa, Ana J Rodrigues, João Filipe Oliveira, Luísa Pint. Beyond New Neurons in the Adult Hippocampus: Imipramine Acts as a Pro-Astrogliogenic Factor and Rescues Cognitive Impairments Induced by Stress Exposure. Cells. vol 11. issue 3. 2022-02-15. PMID:35159199. |
as such, in addition to those resident, the newborn astrocytes in the hippocampal dg might also be promising therapeutic targets for future therapies in the neuropsychiatric field. |
2022-02-15 |
2023-08-13 |
rat |
| Roger McIntosh, Judith D Lobo, Nicole Carvalho, Gail Ironso. Learning to forget: Hippocampal-amygdala connectivity partially mediates the effect of sexual trauma severity on verbal recall in older women undiagnosed with posttraumatic stress disorder. Journal of traumatic stress. 2022-02-14. PMID:35156236. |
in the absence of ptsd sexual trauma symptoms partially relate to verbal learning deficits as a function of aberrant rsfc between left hippocampus dg and right amygdala cm nuclei. |
2022-02-14 |
2023-08-13 |
human |
| Huiqing Lu, Lili Gong, Huangfang Xu, Qiongjie Zhou, Huanqiang Zhao, Suwen Wu, Rong Hu, Xiaotian L. Environmental Enrichment Protects Offspring of a Rat Model of Preeclampsia from Cognitive Decline. Cellular and molecular neurobiology. 2022-02-04. PMID:35119541. |
immunofluorescence was performed to evaluate cell proliferation and apoptosis in the dg region of the hippocampus. |
2022-02-04 |
2023-08-13 |
rat |