| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Raenier V Reyes, Keiko Hino, Cesar Patricio Canales, Eamonn James Dickson, Anna La Torre, Sergi Sim\\xc3\\xb. The E3 Ubiquitin Ligase CRL5 Regulates Dentate Gyrus Morphogenesis, Adult Neurogenesis, and Animal Behavior. Frontiers in neuroscience. vol 16. 2022-07-08. PMID:35801174.' |
given the importance of dg in hippocampal function, it is imperative to understand the molecular mechanisms driving dg development and homeostasis. |
2022-07-08 |
2023-08-14 |
mouse |
| Ying Wei, Li Xiao, Weihao Fan, Jing Zou, Hong Yang, Bo Liu, Yi Ye, Di Wen, Linchuan Lia. Astrocyte Activation, but not Microglia, Is Associated with the Experimental Mouse Model of Schizophrenia Induced by Chronic Ketamine. Journal of molecular neuroscience : MN. 2022-07-08. PMID:35802289. |
moreover, chronic ketamine treatment enhanced gfap expression in ca1 and dg regions of the hippocampus but did not influence the expression of iba-1. |
2022-07-08 |
2023-08-14 |
mouse |
| Yan Liu, Yongliang Pan, Thomas J Curtis, Zuoxin Wan. Amphetamine exposure alters behaviors, and neuronal and neurochemical activation in the brain of female prairie voles. Neuroscience. 2022-07-07. PMID:35798262. |
amph treatment also decreased neuronal activation indicated by the labeling of the early growth response protein 1 (egr-1) as well as the number of neurons double-labeled for egr-1 and corticotrophin-releasing hormone (crh) in the dentate gyrus (dg) of the hippocampus and paraventricular nucleus of the hypothalamus (pvn) in the brain. |
2022-07-07 |
2023-08-14 |
Not clear |
| Saobo Lei, Cody A Boyle, Morgan Mastru. PLCβ-mediated depletion of PIP eNeuro. 2022-07-05. PMID:35788107. |
the dentate gyrus (dg) granule cells (gcs) serve as a gate governing the inflow of information to the hippocampus. |
2022-07-05 |
2023-08-14 |
rat |
| Saobo Lei, Cody A Boyle, Morgan Mastru. PLCβ-mediated depletion of PIP eNeuro. 2022-07-05. PMID:35788107. |
we addressed this question by recording from the dg gcs in rat hippocampal slices. |
2022-07-05 |
2023-08-14 |
rat |
| Wenxin Zhang, Mingqian Yu, Qiyue Zhang, Zhuo Yang, Tao Zhan. DFO treatment protects against depression-like behaviors and cognitive impairment in CUMS mice. Brain research bulletin. 2022-07-02. PMID:35779818. |
additionally, cums exposure significantly decreased the expression of hippocampal synapse related proteins and the spine density of neurons in the dg region, accompanied by increasing the expression of hippocampal inflammatory cytokines, and promoted the activation of microglia in the hippocampus. |
2022-07-02 |
2023-08-14 |
mouse |
| Nick Diederich, Martin Ziegler, Christian Kaernbac. Artificial neural network performance based on correlation analysis qualitatively comparable with human performance in behavioral signal detection experiments. Journal of neurophysiology. 2022-06-29. PMID:35766442. |
to do so, modeling the interaction between the entorhinal cortex (ec) and the hippocampal subnetwork dentate gyrus (dg) via the perforant path reveals the decorrelation network's mode of operation. |
2022-06-29 |
2023-08-14 |
human |
| Marina Mirchandani-Duque, Miguel A Barbancho, Alexander López-Salas, Jose Erik Alvarez-Contino, Natalia García-Casares, Kjell Fuxe, Dasiel O Borroto-Escuela, Manuel Narváe. Galanin and Neuropeptide Y Interaction Enhances Proliferation of Granule Precursor Cells and Expression of Neuroprotective Factors in the Rat Hippocampus with Consequent Augmented Spatial Memory. Biomedicines. vol 10. issue 6. 2022-06-24. PMID:35740319. |
our results suggest the development of heterobivalent agonist pharmacophores, targeting y1r-galr2 heterocomplexes, therefore acting on the neuronal precursor cells of the dg in the dorsal hippocampus for the novel therapy of neurodegenerative cognitive-affecting diseases. |
2022-06-24 |
2023-08-14 |
rat |
| Cristine de Paula Nascimento-Castro, Elisa C Winkelmann-Duarte, Gianni Mancini, Priscilla Gomes Welter, Evelini Plácido, Marcelo Farina, Joana Gil-Mohapel, Ana Lúcia S Rodrigues, Andreza Fabro de Bem, Patricia S Brocard. Temporal Characterization of Behavioral and Hippocampal Dysfunction in the YAC128 Mouse Model of Huntington's Disease. Biomedicines. vol 10. issue 6. 2022-06-24. PMID:35740454. |
however, light and electron microscopy analysis revealed the presence of dark neurons characterized by the intense staining of granule cell bodies and shrunken nuclei and cytoplasm in the hippocampal dentate gyrus (dg) of late symptomatic yac128 mice. |
2022-06-24 |
2023-08-14 |
mouse |
| Cristine de Paula Nascimento-Castro, Elisa C Winkelmann-Duarte, Gianni Mancini, Priscilla Gomes Welter, Evelini Plácido, Marcelo Farina, Joana Gil-Mohapel, Ana Lúcia S Rodrigues, Andreza Fabro de Bem, Patricia S Brocard. Temporal Characterization of Behavioral and Hippocampal Dysfunction in the YAC128 Mouse Model of Huntington's Disease. Biomedicines. vol 10. issue 6. 2022-06-24. PMID:35740454. |
furthermore, structural alterations in the rough endoplasmic reticulum and golgi apparatus were detected in the hippocampal dg of yac128 mice by electron microscopy. |
2022-06-24 |
2023-08-14 |
mouse |
| Cristine de Paula Nascimento-Castro, Elisa C Winkelmann-Duarte, Gianni Mancini, Priscilla Gomes Welter, Evelini Plácido, Marcelo Farina, Joana Gil-Mohapel, Ana Lúcia S Rodrigues, Andreza Fabro de Bem, Patricia S Brocard. Temporal Characterization of Behavioral and Hippocampal Dysfunction in the YAC128 Mouse Model of Huntington's Disease. Biomedicines. vol 10. issue 6. 2022-06-24. PMID:35740454. |
these results clearly show a degenerative process in the hippocampal dg in late symptomatic yac128 animals. |
2022-06-24 |
2023-08-14 |
mouse |
| Yuki Onishi, Yusuke Yamamura, Misa Hosogi, Hiroshi Higashi, Kiyokazu Ogita, Toshihiko Kinjo, Kyosuke Uno, Yukio Yoneda, Nobuyuki Kuramot. Delayed Expression of Both GABA Neurochemical research. 2022-06-23. PMID:35737203. |
the systemic administration of tmt led to declined fluorescence of znaf-2 da staining as a marker of intact mossy fibers and increased fluorescence of fluoro-jade b staining as a marker of degenerated neurons during the initial 2 to 5 days after the administration with later ameliorations within 30 days in the hippocampal dentate gyrus (dg) and ca3 region in mice. |
2022-06-23 |
2023-08-14 |
mouse |
| Zhen Zhang, Jian Li, Bangyue Wang, Changkai Hou, Quanlei Liu, Weihan Wang, Yan Zhao, Qiang Yin, Shuyuan Yang, Hao Zhang, Xinyu Yan. USP22 promotes NSCs stemness maintenance and adult hippocampal neurogenesis, contributing to cognitive recovery following TBI. Neuroscience. 2022-06-14. PMID:35700816. |
interestingly, our data showed that usp22 promotes the proliferation but inhibits the differentiation of nscs in the dentate gyrus (dg)of the hippocampus soon after tbi. |
2022-06-14 |
2023-08-14 |
mouse |
| Cai-N Cheng, Shaw-Jye Wu, Andrew Chih Wei Huan. Environmental Enrichment Components Required to Reduce Methamphetamine-Induced Behavioral Sensitization in Mice: Examination of Behaviors and Neural Substrates. Journal of clinical medicine. vol 11. issue 11. 2022-06-10. PMID:35683439. |
the c-fos expression analysis showed that the medial prefrontal cortex (i.e., cingulate cortex 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), nucleus accumbens (nac), basolateral amygdala (bla), ventral tegmental area (vta), caudate-putamen (cpu), and hippocampus (i.e., ca1, ca3, and dentate gyrus (dg)) contributed to mamph-induced behavioral sensitization. |
2022-06-10 |
2023-08-14 |
mouse |
| Ryuki Tsuchida, Taisei Yamaguchi, Daisuke Funabashi, Yusuke Koumi, Ichiro Kita, Takeshi Nishijim. Exercise type influences the effect of an acute bout of exercise on hippocampal neuronal activation in mice. Neuroscience letters. 2022-06-06. PMID:35660647. |
immunohistochemical examination of c-fos, a marker of neuronal activation, revealed that treadmill exercise at 15 m/min (t15) significantly increased c-fos expression in all subfields of the hippocampus (dentate gyrus dg, ca1, ca3), but rotarod exercise at 30 rpm (r30) did not, as compared with the respective control groups. |
2022-06-06 |
2023-08-14 |
mouse |
| Hu-Jiang Shi, Dan-Lian Wu, Rong Chen, Na Li, Li-Juan Zh. Requirement of hippocampal DG nNOS-CAPON dissociation for the anxiolytic and antidepressant effects of fluoxetine. Theranostics. vol 12. issue 8. 2022-06-06. PMID:35664081. |
requirement of hippocampal dg nnos-capon dissociation for the anxiolytic and antidepressant effects of fluoxetine. |
2022-06-06 |
2023-08-14 |
Not clear |
| Alena Kalinina, Diane Lagac. Single-Cell and Single-Nucleus RNAseq Analysis of Adult Neurogenesis. Cells. vol 11. issue 10. 2022-05-28. PMID:35626670. |
this review summarizes 33 published studies in the field of adult neurogenesis that have used sc- or sn-rnaseq methods to answer questions about the three main regions that host adult neural stem cells (nscs): the subventricular zone (svz), the dentate gyrus (dg) of the hippocampus, and the hypothalamus. |
2022-05-28 |
2023-08-13 |
Not clear |
| Sojeong Pak, Gona Choi, Jaydeep Roy, Chi Him Poon, Jinho Lee, Dajin Cho, Minseok Lee, Lee Wei Lim, Shaowen Bao, Sunggu Yang, Sungchil Yan. Altered synaptic plasticity of the longitudinal dentate gyrus network in noise-induced anxiety. iScience. vol 25. issue 6. 2022-05-27. PMID:35620435. |
anxiety is characteristic comorbidity of noise-induced hearing loss (nihl), which causes physiological changes within the dentate gyrus (dg), a subfield of the hippocampus that modulates anxiety. |
2022-05-27 |
2023-08-13 |
mouse |
| Hyo In Kim, Juhee Lim, Hyo-Jung Choi, Seok-Ho Kim, Hyun Jin Cho. ERRγ Ligand Regulates Adult Neurogenesis and Depression-like Behavior in a LRRK2-G2019S-associated Young Female Mouse Model of Parkinson's Disease. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2022-05-25. PMID:35614294. |
a synthetic errγ ligand, (e)-4-hydroxy-n'-(4-(phenylethynyl)benzylidene)benzohydrazide (hpb2), ameliorated depression-like behavior in young female lrrk2-g2019s mice and enhanced neurogenesis in the hippocampus, as evidenced by increases in the number of bromodeoxyuridine/neuronal nuclei-positive cells and in the intensity and number of doublecortin-positive cells in the hippocampal dentate gyrus (dg). |
2022-05-25 |
2023-08-13 |
mouse |
| Sang-Yoon Kim, Woochang Li. Population and individual firing behaviors in sparsely synchronized rhythms in the hippocampal dentate gyrus. Cognitive neurodynamics. vol 16. issue 3. 2022-05-23. PMID:35603046. |
we investigate population and individual firing behaviors in sparsely synchronized rhythms (ssrs) in a spiking neural network of the hippocampal dentate gyrus (dg). |
2022-05-23 |
2023-08-13 |
Not clear |