| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shunyi Zhao, Jaclyn H DeFinis, Shaoping Ho. Alterations of Dopamine-Related Transcripts in A11 Diencephalospinal Pathways after Spinal Cord Injury. Neural plasticity. vol 2021. 2021-10-27. PMID:33510781. |
the results showed that, compared to naïve rats, mrna levels of tyrosine hydroxylase (th), dopamine decarboxylase (ddc), and d |
2021-10-27 |
2023-08-13 |
rat |
| Hsin-Yun Lin, Hsin-Wei Kuo, Yen-Ling Song, Winton Chen. Cloning and characterization of DOPA decarboxylase in Litopenaeus vannamei and its roles in catecholamine biosynthesis, immunocompetence, and antibacterial defense by dsRNA-mediated gene silencing. Developmental and comparative immunology. vol 108. 2021-09-06. PMID:32145295. |
dopa decarboxylase (ddc), an enzyme responsible for the decarboxylation step of dopamine synthesis, participates in neurotransmitter metabolism and innate immunity. |
2021-09-06 |
2023-08-13 |
Not clear |
| Ioanna Chalatsa, Nikolaos Arvanitis, Dimitrios Arvanitis, Anastasia C Tsakou, Evangelos D Kalantzis, Alice G Vassiliou, Diamantis C Sideris, Efseveia Frakolaki, Niki Vassilaki, Dido Vassilacopoulo. Human L-Dopa decarboxylase interaction with annexin V and expression during apoptosis. Biochimie. vol 177. 2021-05-27. PMID:32835737. |
l-dopa decarboxylase (ddc) is a pyridoxal requiring enzyme that catalyzes the decarboxylation of l-3,4-dihydroxyphenylalanine (l-dopa) to dopamine (da). |
2021-05-27 |
2023-08-13 |
human |
| Claire E Meyer, Juan Liu, Ioana Craciun, Dalin Wu, Hui Wang, Mingqi Xie, Martin Fussenegger, Cornelia G Paliva. Segregated Nanocompartments Containing Therapeutic Enzymes and Imaging Compounds within DNA-Zipped Polymersome Clusters for Advanced Nanotheranostic Platform. Small (Weinheim an der Bergstrasse, Germany). vol 16. issue 27. 2021-05-14. PMID:32130785. |
the therapeutic compartment, loaded with active ddc, triggers the cellular expression of a secreted reporter enzyme via production of dopamine and activation of dopaminergic receptors implicated in atherosclerosis. |
2021-05-14 |
2023-08-13 |
human |
| Yongxin Wen, Jiaping Wang, Qingping Zhang, Yan Chen, Xinhua Ba. The genetic and clinical characteristics of aromatic L-amino acid decarboxylase deficiency in mainland China. Journal of human genetics. vol 65. issue 9. 2021-02-08. PMID:32409695. |
aromatic l-amino acid decarboxylase deficiency (aadcd) is a rare neurotransmitter metabolic disorder caused by ddc gene mutations, which leads to the metabolic disturbance of dopamine and serotonin. |
2021-02-08 |
2023-08-13 |
Not clear |
| Zhong-Jian Shen, Yan-Jun Liu, Fang Zhu, Li-Mei Cai, Xiao-Ming Liu, Zhi-Qiang Tian, Jie Cheng, Zhen Li, Xiao-Xia Li. MicroRNA-277 regulates dopa decarboxylase to control larval-pupal and pupal-adult metamorphosis of Helicoverpa armigera. Insect biochemistry and molecular biology. vol 122. 2021-01-04. PMID:32360955. |
here we show that one mirna, mir-277 regulates larval-pupal and pupal-adult metamorphosis of cotton bollworm by targeting the 3'utr of dopa decarboxylase (ddc), a synthetic catalytic enzyme of dopamine. |
2021-01-04 |
2023-08-13 |
Not clear |
| Jose Pablo Miramontes-Gonzalez, C Makena Hightower, Kuixing Zhang, Hiroki Kurosaki, Andrew J Schork, Nilima Biswas, Sucheta Vaingankar, Manjula Mahata, Michael S Lipkowitz, Caroline M Nievergelt, Dewleen G Baker, Michael G Ziegler, David León-Jiménez, Rogelio González-Sarmiento, Hiroshi Ichinose, Daniel T O'Conno. A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function. Scientific reports. vol 9. issue 1. 2020-10-05. PMID:30911067. |
a new common functional coding variant at the ddc gene change renal enzyme activity and modify renal dopamine function. |
2020-10-05 |
2023-08-13 |
Not clear |
| Michael J Gratz, Stavroula Stavrou, Christina Kuhn, Simone Hofmann, Kerstin Hermelink, Helene Heidegger, Stefan Hutter, Doris Mayr, Sven Mahner, Udo Jeschke, Aurelia Vatta. Dopamine synthesis and dopamine receptor expression are disturbed in recurrent miscarriages. Endocrine connections. vol 7. issue 5. 2020-10-01. PMID:29686031. |
l-dopa decarboxylase (ddc) is responsible for the synthesis of dopamine. |
2020-10-01 |
2023-08-13 |
Not clear |
| Anna Vavřínová, Michal Behuliak, Michal Bencze, Ivana Vaněčková, Josef Zich. Which sympathoadrenal abnormalities of adult spontaneously hypertensive rats can be traced to a prehypertensive stage? Hypertension research : official journal of the Japanese Society of Hypertension. vol 42. issue 7. 2020-09-08. PMID:30651588. |
in the adrenal glands of adult shr, the expression of catecholamine biosynthetic enzymes th, ddc, dbh and pnmt was decreased along the amounts of dopamine and noradrenaline (50% and 38%, respectively, p < 0.001). |
2020-09-08 |
2023-08-13 |
rat |
| Laura Pineda-Cirera, Judit Cabana-Domínguez, Noelia Benetó, Hector Diez, Concepció Arenas, Bru Cormand, Noèlia Fernàndez-Castill. DDC expression is not regulated by NFAT5 (TonEBP) in dopaminergic neural cell lines. Gene. vol 742. 2020-06-01. PMID:32165301. |
a former study reported that nfat5 activation through hypertonic stress increases the expression of the dopa decarboxylase enzyme (ddc), also known as aromatic-l-amino-acid decarboxylase (aadc), in human renal proximal tubule cells, leading to an increase of dopamine synthesis. |
2020-06-01 |
2023-08-13 |
human |
| Laura Pineda-Cirera, Judit Cabana-Domínguez, Noelia Benetó, Hector Diez, Concepció Arenas, Bru Cormand, Noèlia Fernàndez-Castill. DDC expression is not regulated by NFAT5 (TonEBP) in dopaminergic neural cell lines. Gene. vol 742. 2020-06-01. PMID:32165301. |
therefore, to test the hypothesis that nfat5 may also affect dopamine levels in the nervous system through the regulation of ddc expression, we examined this regulation using two neural dopaminergic cell lines, sh-sy5y and pc12. |
2020-06-01 |
2023-08-13 |
human |
| Laura Pineda-Cirera, Judit Cabana-Domínguez, Noelia Benetó, Hector Diez, Concepció Arenas, Bru Cormand, Noèlia Fernàndez-Castill. DDC expression is not regulated by NFAT5 (TonEBP) in dopaminergic neural cell lines. Gene. vol 742. 2020-06-01. PMID:32165301. |
in conclusion, nfat5 does not regulate the expression of the neuronal isoform of ddc in neural dopaminergic cell lines and, consequently, it does not modulate dopamine synthesis through ddc. |
2020-06-01 |
2023-08-13 |
human |
| Efseveia Frakolaki, Katerina I Kalliampakou, Panagiota Kaimou, Maria Moraiti, Nikolaos Kolaitis, Haralabia Boleti, John Koskinas, Dido Vassilacopoulou, Niki Vassilak. Emerging Role of l-Dopa Decarboxylase in Flaviviridae Virus Infections. Cells. vol 8. issue 8. 2020-04-13. PMID:31387309. |
l-dopa decarboxylase (ddc) that catalyzes the biosynthesis of bioactive amines, such as dopamine and serotonin, is expressed in the nervous system and peripheral tissues, including the liver, where its physiological role remains unknown. |
2020-04-13 |
2023-08-13 |
Not clear |
| Jose Pablo Miramontes-Gonzalez, C Makena Hightower, Kuixing Zhang, Hiroki Kurosaki, Andrew J Schork, Nilima Biswas, Sucheta Vaingankar, Manjula Mahata, Michael S Lipkowitz, Caroline M Nievergelt, Dewleen G Baker, Michael G Ziegler, David León-Jiménez, Rogelio González-Sarmiento, Hiroshi Ichinose, Daniel T O'Conno. Author Correction: A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function. Scientific reports. vol 10. issue 1. 2020-02-25. PMID:32060363. |
author correction: a new common functional coding variant at the ddc gene change renal enzyme activity and modify renal dopamine function. |
2020-02-25 |
2023-08-13 |
Not clear |
| Jianqiang Lan, Zhongqiang Liu, Chenghong Liao, David J Merkler, Qian Han, Jianyong L. A Study for Therapeutic Treatment against Parkinson's Disease via Chou's 5-steps Rule. Current topics in medicinal chemistry. vol 19. issue 25. 2019-12-17. PMID:31629395. |
the enzyme l-dopa decarboxylase (ddc), also called aromatic-l-amino-acid decarboxylase, catalyzes the biosynthesis of dopamine, serotonin, and trace amines. |
2019-12-17 |
2023-08-13 |
Not clear |
| Kai Wang, Qian Ren, Xiu-Li Shen, Bo Li, Jie Du, Xiao-Dong Yu, Zhi-Qiang D. Molecular characterization and expression analysis of dopa decarboxylase involved in the antibacterial innate immunity of the freshwater crayfish, Procambarus clarkii. Fish & shellfish immunology. vol 91. 2019-10-29. PMID:31077848. |
dopa decarboxylase (ddc) is responsible for the synthesis of dopamine, which acts as an important modulator in the nervous systems of vertebrates and invertebrates. |
2019-10-29 |
2023-08-13 |
Not clear |
| Chi-Ren Tsai, Hsiu-Fen Lee, Ching-Shiang Chi, Ming-Te Yang, Chia-Chi Hs. Antisense oligonucleotides modulate dopa decarboxylase function in aromatic l-amino acid decarboxylase deficiency. Human mutation. vol 39. issue 12. 2019-10-07. PMID:30260058. |
aromatic l-amino acid decarboxylase deficiency (aadcd), attributed to mutations in the dopa decarboxylase (ddc) gene, is a rare neurometabolic disease resulting from a defect in the biosynthesis of dopamine and serotonin. |
2019-10-07 |
2023-08-13 |
Not clear |
| Jie Bi, Amita Sehgal, Julie A Williams, Yu-Feng Wan. Wolbachia affects sleep behavior in Drosophila melanogaster. Journal of insect physiology. vol 107. 2019-09-25. PMID:29499213. |
transcriptional analysis of the dopamine biosynthesis pathway revealed that two essential genes, pale and ddc, were significantly upregulated in wolbachia-infected flies. |
2019-09-25 |
2023-08-13 |
drosophila_melanogaster |
| Alice G Vassiliou, Maria-Zacharenia Siaterli, Efseveia Frakolaki, Panayiota Gkogkosi, Ioannis Paspaltsis, Theodoros Sklaviadis, Dido Vassilacopoulou, Niki Vassilak. L-Dopa decarboxylase interaction with the major signaling regulator ΡΙ3Κ in tissues and cells of neural and peripheral origin. Biochimie. vol 160. 2019-07-08. PMID:30796964. |
l-dopa decarboxylase (ddc) catalyzes the decarboxylation of l-dopa to dopamine and 5-hydroxytryptophan (5-htp) to serotonin. |
2019-07-08 |
2023-08-13 |
mouse |
| Andrew E Christie, Meredith E Stanhope, Helen I Gandler, Tess J Lameyer, Micah G Pascual, Devlin N Shea, Andy Yu, Patsy S Dickinson, J Joe Hul. Molecular characterization of putative neuropeptide, amine, diffusible gas and small molecule transmitter biosynthetic enzymes in the eyestalk ganglia of the American lobster, Homarus americanus. Invertebrate neuroscience : IN. vol 18. issue 4. 2019-05-28. PMID:30276482. |
similarly, transcripts encoding full complements of the enzymes responsible for dopamine [tryptophan-phenylalanine hydroxylase (tph), tyrosine hydroxylase and dopa decarboxylase (ddc)], octopamine (tph, tyrosine decarboxylase and tyramine β-hydroxylase), serotonin (tph or tryptophan hydroxylase and ddc) and histamine (histidine decarboxylase) biosynthesis were identified from the eyestalk ganglia, as were those responsible for the generation of the gases nitric oxide (nitric oxide synthase) and carbon monoxide (heme oxygenase), and the small molecule transmitters acetylcholine (choline acetyltransferase), glutamate (glutaminase) and gaba (glutamic acid decarboxylase). |
2019-05-28 |
2023-08-13 |
lobster |