| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L T Chow, S S Chow, R H Anderson, J A Goslin. Autonomic innervation of the human cardiac conduction system: changes from infancy to senility--an immunohistochemical and histochemical analysis. The Anatomical record. vol 264. issue 2. 2001-12-05. PMID:11590594. |
the pattern of distribution and density of nerves exhibiting immunoreactivity against protein gene product 9.5 (pgp), a general neural marker, dopamine beta-hydroxylase (dbh) and tyrosine hydroxylase (th), indicators for presumptive sympathetic neural tissue, and those demonstrating positive acetylcholinesterase (ache) activity, were studied. |
2001-12-05 |
2023-08-12 |
human |
| S Y Choi, B H Choi, B C Suh, H D Chae, J S Kim, M J Shin, S S Kang, M Negishi, K T Ki. Potentiation of PGE(2)-mediated cAMP production during neuronal differentiation of human neuroblastoma SK-N-BE(2)C cells. Journal of neurochemistry. vol 79. issue 2. 2001-12-04. PMID:11677258. |
northern blot analysis using the human cdna probes shows that the ep(2) mrna level was about seven times higher in differentiated cells, while the dopamine beta-hydroxylase (dbh) mrna completely disappeared. |
2001-12-04 |
2023-08-12 |
human |
| A K Goodchild, J K Phillips, J Lipski, P M Pilowsk. Differential expression of catecholamine synthetic enzymes in the caudal ventral pons. The Journal of comparative neurology. vol 438. issue 4. 2001-10-25. PMID:11559901. |
in extending this study to include the caudal pons, it was shown for the first time that the a5 cell group could be distinguished by the presence of immunoreactivity to tyrosine hydroxylase (th), aromatic l-amino acid decarboxylase (aadc), and dopamine beta hydroxylase (dbh). |
2001-10-25 |
2023-08-12 |
rat |
| D Weinshenker, P Szot, N S Miller, N C Rust, J G Hohmann, U Pyati, S S White, R D Palmite. Genetic comparison of seizure control by norepinephrine and neuropeptide Y. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 19. 2001-10-11. PMID:11567066. |
npy knock-out (npy ko) and dopamine beta-hydroxylase knock-out (dbh ko) mice that lack ne are susceptible to seizures, and agonists of ne and npy receptors protect against seizures. |
2001-10-11 |
2023-08-12 |
mouse |
| P Szot, D Weinshenker, J M Rho, T W Storey, P A Schwartzkroi. Norepinephrine is required for the anticonvulsant effect of the ketogenic diet. Brain research. Developmental brain research. vol 129. issue 2. 2001-09-27. PMID:11506865. |
to determine if the noradrenergic system has a role in mediating the anticonvulsant action of the kd, dopamine beta-hydroxylase knockout (dbh -/-) mice that lack norepinephrine (ne) and dbh +/- littermates that have normal ne content were fed either a standard rodent chow or the kd. |
2001-09-27 |
2023-08-12 |
mouse |
| H Q Yan, A E Kline, X Ma, E L Hooghe-Peters, D W Marion, C E Dixo. Tyrosine hydroxylase, but not dopamine beta-hydroxylase, is increased in rat frontal cortex after traumatic brain injury. Neuroreport. vol 12. issue 11. 2001-09-20. PMID:11496104. |
to test this, tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) levels were examined by immunohistochemistry and western blot at 1, 7, 14, and 28 days after tbi or sham surgery. |
2001-09-20 |
2023-08-12 |
rat |
| D Weinshenker, P Szot, N S Miller, R D Palmite. Alpha(1) and beta(2) adrenoreceptor agonists inhibit pentylenetetrazole-induced seizures in mice lacking norepinephrine. The Journal of pharmacology and experimental therapeutics. vol 298. issue 3. 2001-09-13. PMID:11504801. |
we sought to circumvent these problems by testing the anticonvulsant activity of selective agonists for most known adrenoreceptors (ars) in dopamine beta-hydroxylase knockout (dbh -/-) mice that lack endogenous ne. |
2001-09-13 |
2023-08-12 |
mouse |
| N Markoglou, I W Waine. Synthesis and characterization of immobilized dopamine beta-hydroxylase in membrane-bound and solubilized formats. Journal of biochemical and biophysical methods. vol 48. issue 1. 2001-08-02. PMID:11282402. |
dopamine beta-hydroxylase (dbh) catalyzes the beta-hydroxylation of dopamine to norepinephrine. |
2001-08-02 |
2023-08-12 |
Not clear |
| P D Robinson, C K Schutz, F Macciardi, B N White, J J Holde. Genetically determined low maternal serum dopamine beta-hydroxylase levels and the etiology of autism spectrum disorders. American journal of medical genetics. vol 100. issue 1. 2001-07-26. PMID:11337745. |
since previous findings showed that some families with autistic children have a low level of serum dopamine beta-hydroxylase (dbetah), which catalyzes the conversion of dopamine to norepinephrine, we examined the dbh gene as a candidate locus in families with two or more children with autism spectrum disorder using the affected sib-pair method. |
2001-07-26 |
2023-08-12 |
Not clear |
| A K Knecht, M Bronner-Frase. DBHR, a gene with homology to dopamine beta-hydroxylase, is expressed in the neural crest throughout early development. Developmental biology. vol 234. issue 2. 2001-07-26. PMID:11397006. |
in a screen for genes involved in neural crest development, we identified dbhr (dbh-related), a putative monooxygenase with low homology to dopamine beta-hydroxylase (dbh). |
2001-07-26 |
2023-08-12 |
Not clear |
| J K Phillips, R Dubey, E Sesiashvilvi, M Takeda, D L Christie, J Lipsk. Differential expression of the noradrenaline transporter in adrenergic chromaffin cells, ganglion cells and nerve fibres of the rat adrenal medulla. Journal of chemical neuroanatomy. vol 21. issue 1. 2001-05-10. PMID:11173223. |
immunoreactivity for the catecholamine biosynthetic enzymes tyrosine hydroxylase (th), aromatic-l-amino-acid decarboxylase (aadc) and dopamine beta-hydroxylase (dbh) was present in all chromaffin cells, while phenylethanolamine n-methyltransferase (pnmt) was used to determine adrenergic chromaffin cell groups. |
2001-05-10 |
2023-08-12 |
rat |
| J K Phillips, A K Goodchild, R Dubey, E Sesiashvili, M Takeda, J Chalmers, P M Pilowsky, J Lipsk. Differential expression of catecholamine biosynthetic enzymes in the rat ventrolateral medulla. The Journal of comparative neurology. vol 432. issue 1. 2001-05-03. PMID:11241375. |
however, no studies have simultaneously demonstrated the expression of aromatic l-amino acid decarboxylase (aadc) and dopamine beta-hydroxylase (dbh) in these neurons. |
2001-05-03 |
2023-08-12 |
rat |
| P Slama, F Jabre, T Tron, M Réglie. Dopamine beta-hydroxylase inactivation generates a protein-bound quinone derivative. FEBS letters. vol 491. issue 1-2. 2001-04-26. PMID:11226418. |
bovine dopamine beta-hydroxylase (dbh) was inactivated by hydrogen peroxide and ascorbate in the presence of dioxygen. |
2001-04-26 |
2023-08-12 |
cattle |
| R A Lea, A Dohy, K Jordan, S Quinlan, P J Brimage, L R Griffith. Evidence for allelic association of the dopamine beta-hydroxylase gene (DBH) with susceptibility to typical migraine. Neurogenetics. vol 3. issue 1. 2001-02-22. PMID:11085595. |
evidence for allelic association of the dopamine beta-hydroxylase gene (dbh) with susceptibility to typical migraine. |
2001-02-22 |
2023-08-12 |
Not clear |
| R A Lea, A Dohy, K Jordan, S Quinlan, P J Brimage, L R Griffith. Evidence for allelic association of the dopamine beta-hydroxylase gene (DBH) with susceptibility to typical migraine. Neurogenetics. vol 3. issue 1. 2001-02-22. PMID:11085595. |
polymorphisms within the dopamine beta-hydroxylase (dbh) gene, serotonin transporter gene (sert), and dopamine receptor gene (drd2) were tested in 177 unrelated caucasian migraineurs and 182 control individuals. |
2001-02-22 |
2023-08-12 |
Not clear |
| H S Kim, S J Hong, M S LeDoux, K S Ki. Regulation of the tyrosine hydroxylase and dopamine beta-hydroxylase genes by the transcription factor AP-2. Journal of neurochemistry. vol 76. issue 1. 2001-02-08. PMID:11146001. |
in this study, transcriptional regulation of tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) genes by ap-2 was investigated. |
2001-02-08 |
2023-08-12 |
Not clear |
| E F McKinney, R T Walton, P Yudkin, A Fuller, N A Haldar, D Mant, M Murphy, K I Welsh, S E Marshal. Association between polymorphisms in dopamine metabolic enzymes and tobacco consumption in smokers. Pharmacogenetics. vol 10. issue 6. 2001-01-25. PMID:10975602. |
we developed assays for polymorphisms in dopamine beta-hydroxylase (dbh), monoamine oxidase (mao) and catechol o-methyl transferase (comt) using the polymerase chain reaction with sequence specific primers (pcr-ssp). |
2001-01-25 |
2023-08-12 |
Not clear |
| C Thibault, C Lai, N Wilke, B Duong, M F Olive, S Rahman, H Dong, C W Hodge, D J Lockhart, M F Mile. Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression. Molecular pharmacology. vol 58. issue 6. 2001-01-18. PMID:11093800. |
ethanol treatment elevated dopamine beta-hydroxylase (dbh, ec 1.14.17.1) mrna and protein levels and increased releasable norepinephrine in sh-sy5y cultures. |
2001-01-18 |
2023-08-12 |
mouse |
| V D Gueorguiev, R J Zeman, E M Meyer, E L Sabba. Involvement of alpha7 nicotinic acetylcholine receptors in activation of tyrosine hydroxylase and dopamine beta-hydroxylase gene expression in PC12 cells. Journal of neurochemistry. vol 75. issue 5. 2000-11-09. PMID:11032889. |
nicotine treatment increases intracellular free ca(2+) concentration [ca(2+)](i), stimulates catecholamine release, and elevates gene expression for the catecholamine biosynthetic enzymes tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh). |
2000-11-09 |
2023-08-12 |
Not clear |
| M H Gladden, D J Maxwell, A Sahal, E Jankowsk. Coupling between serotoninergic and noradrenergic neurones and gamma-motoneurones in the cat. The Journal of physiology. vol 527 Pt 2. 2000-11-07. PMID:10970424. |
eight gamma-motoneurones were labelled with rhodamine-dextran, and 50 micrometer thick sagittal sections of the spinal cord containing them were exposed to antibodies against dopamine beta-hydroxylase (dbh) and 5-ht. |
2000-11-07 |
2023-08-12 |
cat |