| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Serova, E L Sabban, A Zangen, D H Overstreet, G Yadi. Altered gene expression for catecholamine biosynthetic enzymes and stress response in rat genetic model of depression. Brain research. Molecular brain research. vol 63. issue 1. 1999-01-21. PMID:9838081. |
in adrenals, basal levels of tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), phenylethanolamine n-methyltransferase (pnmt) and gtp cyclohydrolase i (gtpch) mrnas were markedly elevated in fsl rats compared to the control strain. |
1999-01-21 |
2023-08-12 |
rat |
| D A Demeter, H J Weintraub, J J Knitte. The local minima method (LMM) of pharmacophore determination: a protocol for predicting the bioactive conformation of small, conformationally flexible molecules. Journal of chemical information and computer sciences. vol 38. issue 6. 1999-01-06. PMID:9845967. |
lmm was used to develop a 3d-qsar model for dopamine beta-hydroxylase (dbh) inhibitors which was highly predictive (predictive r2 = 0.71 and standard error of predictions = 0.41). |
1999-01-06 |
2023-08-12 |
Not clear |
| E B Jacobsen, I Fristad, K J Heyeraa. Nerve fibers immunoreactive to calcitonin gene-related peptide, substance P, neuropeptide Y, and dopamine beta-hydroxylase in innervated and denervated oral tissues in ferrets. Acta odontologica Scandinavica. vol 56. issue 4. 1998-12-08. PMID:9765014. |
the effect of sensory and sympathetic denervation on the localization and distribution of nerve fibers immunoreactive (ir) to calcitonin gene-related peptide (cgrp), substance p (sp), neuropeptide y (npy), and dopamine beta-hydroxylase (dbh) was studied in the dental pulp, periodontal ligament (pdl), and gingiva in ferrets. |
1998-12-08 |
2023-08-12 |
Not clear |
| C Yang, H S Kim, H Seo, C H Kim, J F Brunet, K S Ki. Paired-like homeodomain proteins, Phox2a and Phox2b, are responsible for noradrenergic cell-specific transcription of the dopamine beta-hydroxylase gene. Journal of neurochemistry. vol 71. issue 5. 1998-11-30. PMID:9798905. |
in noradrenergic neurons, dopamine beta-hydroxylase (dbh) is a hallmark protein and catalyzes the conversion of dopamine to noradrenaline. |
1998-11-30 |
2023-08-12 |
Not clear |
| M B Hamner, P B Gol. Plasma dopamine beta-hydroxylase activity in psychotic and non-psychotic post-traumatic stress disorder. Psychiatry research. vol 77. issue 3. 1998-11-06. PMID:9707300. |
altered dopamine beta-hydroxylase (dbh) activity has been reported in mood disorders. |
1998-11-06 |
2023-08-12 |
human |
| M Srivastava, H B Pollard, P J Flemin. Mouse cytochrome b561: cDNA cloning and expression in rat brain, mouse embryos, and human glioma cell lines. DNA and cell biology. vol 17. issue 9. 1998-10-28. PMID:9778036. |
because non-neuronal cells in the central nervous system contained peptidyl alpha-amidating monooxygenase (pam), to which cytochrome b561 donates its electrons, we used rt-pcr to document the coexpression of cytochrome b561 with pam and dopamine beta-hydroxylase (dbh) in glioblastoma cells. |
1998-10-28 |
2023-08-12 |
mouse |
| H S Kim, H Seo, C Yang, J F Brunet, K S Ki. Noradrenergic-specific transcription of the dopamine beta-hydroxylase gene requires synergy of multiple cis-acting elements including at least two Phox2a-binding sites. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 20. 1998-10-23. PMID:9763470. |
dopamine beta-hydroxylase (dbh) catalyzes the conversion of dopamine to noradrenaline and is selectively expressed in noradrenergic and adrenergic neurons and neuroendocrine cells. |
1998-10-23 |
2023-08-12 |
human |
| J Rodrigo, P Fernández, M L Bentura, J M de Velasco, J Serrano, O Uttenthal, R Martínez-Murill. Distribution of catecholaminergic afferent fibres in the rat globus pallidus and their relations with cholinergic neurons. Journal of chemical neuroanatomy. vol 15. issue 1. 1998-10-22. PMID:9710145. |
peroxidase-antiperoxidase and two-colour immunoperoxidase staining procedures were used to demonstrate tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), phenylethanolamine n-methyltransferase (pnmt) and choline acetyltransferase (chat) immunoreactivities, combined with acetylcholinesterase (ache) pharmacohistochemistry. |
1998-10-22 |
2023-08-12 |
rat |
| K J Chambers, L A Tonkin, E Chang, D N Shelton, M H Linskens, W D Fun. Identification and cloning of a sequence homologue of dopamine beta-hydroxylase. Gene. vol 218. issue 1-2. 1998-10-22. PMID:9751809. |
this novel enzyme, which we call mox (monooxygenase x; unknown substrate) is a clear sequence homologue of the enzyme dopamine beta-hydroxylase (dbh). |
1998-10-22 |
2023-08-12 |
mouse |
| C Yang, H S Kim, H Seo, K S Ki. Identification and characterization of potential cis-regulatory elements governing transcriptional activation of the rat tyrosine hydroxylase gene. Journal of neurochemistry. vol 71. issue 4. 1998-10-14. PMID:9751166. |
first, using transient transfection assays, we examined the cell-specific promoter activities of th-reporter gene constructs and a dopamine beta-hydroxylase (dbh)-reporter construct containing the 5' upstream sequences of the rat th and human dbh genes, respectively, that had been shown to direct tissue-specific reporter expression in transgenic mice experiments. |
1998-10-14 |
2023-08-12 |
mouse |
| A Mayerhofer, G D Smith, M Danilchik, J E Levine, D P Wolf, G A Dissen, S R Ojed. Oocytes are a source of catecholamines in the primate ovary: evidence for a cell-cell regulatory loop. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 18. 1998-09-28. PMID:9724817. |
we now show that the primate ovary expresses both the genes encoding th and dopamine beta-hydroxylase (dbh), the key enzymes in norepinephrine (ne) biosynthesis. |
1998-09-28 |
2023-08-12 |
human |
| M A Elwan, R Thangavel, F Ono, N Sakuragaw. Synthesis and release of catecholamines by cultured monkey amniotic epithelial cells. Journal of neuroscience research. vol 53. issue 1. 1998-09-24. PMID:9670997. |
immunocytochemical techniques demonstrated the presence of tyrosine hydroxylase (th), aromatic l-amino acid decarboxylase (aadc), dopamine-beta-hydroxylase (dbh), and dopamine (da) immunoreactivities, suggesting the capability of these cells to synthesize ca. |
1998-09-24 |
2023-08-12 |
monkey |
| H Ishiguro, K Yamada, N Ichino, T Nagats. Identification and characterization of a novel phorbol ester-responsive DNA sequence in the 5'-flanking region of the human dopamine beta-hydroxylase gene. The Journal of biological chemistry. vol 273. issue 34. 1998-09-17. PMID:9705334. |
the phorbol ester, 12-o-tetradecanoylphorbol-13-acetate (tpa), enhances transcription of many eukaryotic genes, including that for dopamine beta-hydroxylase (dbh). |
1998-09-17 |
2023-08-12 |
human |
| J S Dixon, P Y Jen, J A Goslin. Immunohistochemical characteristics of human paraganglion cells and sensory corpuscles associated with the urinary bladder. A developmental study in the male fetus, neonate and infant. Journal of anatomy. vol 192 ( Pt 3). 1998-09-11. PMID:9688506. |
triple label immunohistochemistry was used to study the coexistence of the catecholamine-synthesising enzymes dopamine beta-hydroxylase (dbh) and tyrosine hydroxylase (th) and several neuropeptides including neuropeptide y (npy), vasoactive intestinal polypeptide (vip), substance p (sp), calcitonin gene-related peptide (cgrp), somatostatin (som) and galanin (gal) as well as nitric oxide synthase (nos) in developing pelvic paraganglion cells in a series of human male fetal, neonatal and infant specimens ranging in age from 13 wk of gestation to 3 y postnatal. |
1998-09-11 |
2023-08-12 |
human |
| D C Silveira, Z Liu, G L Holmes, D L Schomer, S C Schachte. Seizures in rats treated with kainic acid induce Fos-like immunoreactivity in locus coeruleus. Neuroreport. vol 9. issue 7. 1998-08-24. PMID:9631428. |
following kats, brain stem sections were stained for fos immunocytochemistry and double immunostained for fos and dopamine beta-hydroxylase (dbh). |
1998-08-24 |
2023-08-12 |
rat |
| T R Macedo, C A Ribeiro, T Morgadinho, M A Abre. Influence of concurrent heroin and cocaine abuse on the adrenergic and serotonergic systems in man. Annals of the New York Academy of Sciences. vol 844. 1998-08-13. PMID:9668679. |
free and sulfoconjugated catecholamines and serotonin (5-hydroxytryptamine, 5-ht) were measured by high-performance liquid chromatography with electrochemical detection (hplc-ecd); plasma dopamine (da)-beta-hydroxylase (dbh) activity was determined by a hplc technique. |
1998-08-13 |
2023-08-12 |
human |
| J F Cubells, D P van Kammen, M E Kelley, G M Anderson, D T O'Connor, L H Price, R Malison, P A Rao, K Kobayashi, T Nagatsu, J Gelernte. Dopamine beta-hydroxylase: two polymorphisms in linkage disequilibrium at the structural gene DBH associate with biochemical phenotypic variation. Human genetics. vol 102. issue 5. 1998-07-16. PMID:9654201. |
dopamine beta-hydroxylase: two polymorphisms in linkage disequilibrium at the structural gene dbh associate with biochemical phenotypic variation. |
1998-07-16 |
2023-08-12 |
human |
| H S Kim, C Yang, K S Ki. The cell-specific silencer region of the human dopamine beta-hydroxylase gene contains several negative regulatory elements. Journal of neurochemistry. vol 71. issue 1. 1998-07-09. PMID:9648849. |
dopamine beta-hydroxylase (dbh) catalyzes the conversion of dopamine to noradrenaline and is selectively expressed in noradrenergic and adrenergic neurons in the nervous system. |
1998-07-09 |
2023-08-12 |
human |
| J Wei, C N Ramchand, G P Hemming. TaqI polymorphic sites at the human dopamine beta-hydroxylase gene possibly associated with biochemical alterations of the catecholamine pathway in schizophrenia. Psychiatric genetics. vol 8. issue 1. 1998-06-08. PMID:9564683. |
two parts of the dopamine beta-hydroxylase (dbh) gene, one a 7.5-kb single copy fragment (f1) spanning the 5'-flanking region to exon 3 and the second a 9.0-kb single copy fragment (f2) spanning exon 3 to exon 7, were amplified by a long pcr procedure in 161 unrelated patients with schizophrenia and 67 unrelated control subjects. |
1998-06-08 |
2023-08-12 |
human |
| S A Thomas, B T Marck, R D Palmiter, A M Matsumot. Restoration of norepinephrine and reversal of phenotypes in mice lacking dopamine beta-hydroxylase. Journal of neurochemistry. vol 70. issue 6. 1998-06-05. PMID:9603211. |
mice with a targeted disruption of the dopamine beta-hydroxylase (dbh) gene are unable to synthesize norepinephrine (ne) and epinephrine. |
1998-06-05 |
2023-08-12 |
mouse |